Project measure / variable:   GMC11   GLU_30

ID, description, units MPD:56013   GLU_30   intraperitoneal glucose tolerance test (20% glucose i.p., 16h fast)   [mmol/L]  at 30 min  
Data set, strains GMC11   inbred   6 strains     sex: both     age: 13-14wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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GMC11 - intraperitoneal glucose tolerance test (20% glucose i.p., 16h fast) at 30 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means16.4   mmol/L 19.5   mmol/L
Median of the strain means15.6   mmol/L 18.6   mmol/L
SD of the strain means± 4.64 ± 3.53
Coefficient of variation (CV)0.282 0.181
Min–max range of strain means10.8   –   22.3   mmol/L 15.1   –   23.9   mmol/L
Mean sample size per strain13.7   mice 15.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 244.5688 244.5688 16.4112 0.0001
strain 4 2385.7923 596.4481 40.0232 < 0.0001
sex:strain 4 51.7361 12.934 0.8679 0.4848
Residuals 150 2235.3843 14.9026


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.8 2.15   16 0.537 0.198 8.16, 14.9 -1.22
129S1/SvImJ m 15.1 3.34   16 0.836 0.221 8.94, 20.0 -1.23
A/J f 15.9 2.94   15 0.758 0.185 11.1, 20.5 -0.12
A/J m 19.3 3.64   16 0.911 0.189 13.4, 28.0 -0.04
C57BL/6J f 21.6 2.3   16 0.575 0.106 17.5, 26.5 1.11
C57BL/6J m 23.9 2.89   16 0.722 0.121 20.3, 32.8 1.26
NOD/ShiLtJ f 15.3 6.8   17 1.65 0.445 5.94, 32.0 -0.25
NOD/ShiLtJ m 17.1 3.14   16 0.786 0.184 12.5, 22.5 -0.67
NZO/HlLtJ f 22.3 4.69   17 1.14 0.21 11.4, 31.3 1.26
NZO/HlLtJ m 23.4 4.08   15 1.05 0.174 16.1, 31.3 1.12
PWK/PhJ f 12.8 0.0   1   0.0 0.0 12.8, 12.8 -0.79
PWK/PhJ m 17.9 4.09   12 1.18 0.228 11.5, 25.0 -0.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.8356 0.9651 12.7426 8.9287
129S1/SvImJ m 15.1231 0.9651 17.0301 13.2162
A/J f 15.886 0.9967 17.8555 13.9165
A/J m 19.2737 0.9651 21.1807 17.3668
C57BL/6J f 21.6344 0.9651 23.5413 19.7274
C57BL/6J m 23.9456 0.9651 25.8526 22.0387
NOD/ShiLtJ f 15.3035 0.9363 17.1535 13.4535
NOD/ShiLtJ m 17.1094 0.9651 19.0163 15.2024
NZO/HlLtJ f 22.33 0.9363 24.18 20.48
NZO/HlLtJ m 23.4133 0.9967 25.3828 21.4439


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 12.9794 0.6824 14.3278 11.631
A/J both 17.5799 0.6937 18.9506 16.2092
C57BL/6J both 22.79 0.6824 24.1384 21.4416
NOD/ShiLtJ both 16.2065 0.6723 17.5349 14.878
NZO/HlLtJ both 22.8717 0.6838 24.2227 21.5206




  GWAS USING LINEAR MIXED MODELS