Project measure / variable:   GMC05   PPI_ISI_100

ID, description, units MPD:55453   PPI_ISI_100   prepulse inhibition (PPI)   [%]  PP2 inter-stimulus interval: 100  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - prepulse inhibition (PPI) PP2 inter-stimulus interval: 100



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means28.4   % 22.8   %
Median of the strain means30.9   % 23.7   %
SD of the strain means± 18.1 ± 18.9
Coefficient of variation (CV)0.636 0.829
Min–max range of strain means-3.09   –   50.1   % -6.26   –   47.5   %
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2131.4903 2131.4903 4.6636 0.0318
strain 7 69119.6477 9874.2354 21.6045 < 0.0001
sex:strain 7 8009.4265 1144.2038 2.5035 0.0167
Residuals 250 114261.5509 457.0462


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 47.8 17.5   16 4.38 0.367 11.1, 70.2 1.07
129S1/SvImJ m 36.3 14.6   16 3.65 0.402 13.1, 59.6 0.71
A/J f -3.09 39.2   16 9.81 -12.7 -84.6, 43.6 -1.74
A/J m -6.26 27.1   16 6.77 -4.32 -46.9, 41.3 -1.54
C57BL/6J f 50.1 9.34   16 2.33 0.186 32.8, 68.8 1.2
C57BL/6J m 47.5 12.4   16 3.11 0.261 23.1, 69.6 1.31
CAST/EiJ f 31.0 13.2   19 3.04 0.427 10.8, 51.2 0.14
CAST/EiJ m 35.3 15.1   18 3.56 0.427 6.8, 63.7 0.66
NOD/ShiLtJ f 34.1 19.8   18 4.66 0.581 -1.2, 65.9 0.32
NOD/ShiLtJ m 8.68 22.8   16 5.7 2.63 -38.5, 48.0 -0.75
NZO/HlLtJ f 8.44 16.2   16 4.05 1.92 -16.4, 30.1 -1.11
NZO/HlLtJ m 12.1 17.5   16 4.38 1.45 -15.7, 39.0 -0.57
PWK/PhJ f 28.1 18.2   16 4.56 0.648 -1.0, 58.5 -0.02
PWK/PhJ m 10.4 17.0   17 4.12 1.63 -33.9, 34.9 -0.66
WSB/EiJ f 30.7 36.5   18 8.61 1.19 -42.5, 73.3 0.13
WSB/EiJ m 38.4 20.7   16 5.18 0.54 -1.6, 66.3 0.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 47.7812 5.3447 58.3075 37.255
129S1/SvImJ m 36.325 5.3447 46.8513 25.7987
A/J f -3.0875 5.3447 7.4388 -13.6138
A/J m -6.2625 5.3447 4.2638 -16.7888
C57BL/6J f 50.0875 5.3447 60.6138 39.5612
C57BL/6J m 47.5187 5.3447 58.045 36.9925
CAST/EiJ f 30.9947 4.9046 40.6543 21.3351
CAST/EiJ m 35.3222 5.039 45.2465 25.3979
NOD/ShiLtJ f 34.0611 5.039 43.9854 24.1368
NOD/ShiLtJ m 8.6813 5.3447 19.2075 -1.845
NZO/HlLtJ f 8.4375 5.3447 18.9638 -2.0888
NZO/HlLtJ m 12.0875 5.3447 22.6138 1.5612
PWK/PhJ f 28.1375 5.3447 38.6638 17.6112
PWK/PhJ m 10.4059 5.1851 20.6179 0.1939
WSB/EiJ f 30.7 5.039 40.6243 20.7757
WSB/EiJ m 38.375 5.3447 48.9013 27.8487


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 42.0531 3.7792 49.4963 34.6099
A/J both -4.675 3.7792 2.7682 -12.1182
C57BL/6J both 48.8031 3.7792 56.2463 41.3599
CAST/EiJ both 33.1585 3.5159 40.0831 26.2339
NOD/ShiLtJ both 21.3712 3.6728 28.6047 14.1377
NZO/HlLtJ both 10.2625 3.7792 17.7057 2.8193
PWK/PhJ both 19.2717 3.7233 26.6046 11.9387
WSB/EiJ both 34.5375 3.6728 41.771 27.304




  GWAS USING LINEAR MIXED MODELS