Project measure / variable:   GMC05   PPI_ISI_25

ID, description, units MPD:55452   PPI_ISI_25   prepulse inhibition (PPI)   [%]  PP2 inter-stimulus interval: 25  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - prepulse inhibition (PPI) PP2 inter-stimulus interval: 25



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means35.8   % 35.8   %
Median of the strain means34.9   % 31.1   %
SD of the strain means± 27.9 ± 22.5
Coefficient of variation (CV)0.779 0.628
Min–max range of strain means-12.7   –   80.0   % 11.5   –   71.9   %
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.3957 1.3957 0.0024 0.9607
strain 7 131736.3595 18819.4799 32.8871 < 0.0001
sex:strain 7 12698.0205 1814.0029 3.17 0.0031
Residuals 250 143061.3515 572.2454


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 80.0 12.0   16 3.0 0.15 43.0, 89.5 1.59
129S1/SvImJ m 71.9 12.6   16 3.15 0.175 42.4, 90.2 1.6
A/J f -12.7 39.1   16 9.77 -3.08 -85.4, 32.8 -1.74
A/J m 11.5 21.2   16 5.29 1.84 -20.3, 46.4 -1.08
C57BL/6J f 59.0 11.3   16 2.83 0.192 41.9, 75.8 0.83
C57BL/6J m 63.5 10.0   16 2.5 0.158 45.9, 86.5 1.23
CAST/EiJ f 45.8 16.3   19 3.74 0.356 17.0, 66.2 0.36
CAST/EiJ m 42.7 15.2   18 3.59 0.356 16.1, 69.6 0.31
NOD/ShiLtJ f 37.9 20.8   18 4.9 0.548 -12.7, 71.6 0.08
NOD/ShiLtJ m 13.8 24.0   16 6.0 1.74 -31.5, 53.6 -0.98
NZO/HlLtJ f 14.9 19.9   16 4.97 1.33 -25.6, 40.5 -0.75
NZO/HlLtJ m 24.5 24.1   16 6.02 0.984 -13.5, 63.1 -0.5
PWK/PhJ f 31.9 28.7   16 7.17 0.898 -17.8, 72.1 -0.14
PWK/PhJ m 20.9 20.3   17 4.93 0.971 -20.5, 49.7 -0.66
WSB/EiJ f 29.5 41.1   18 9.68 1.39 -67.7, 65.0 -0.23
WSB/EiJ m 37.7 35.1   16 8.77 0.93 -50.6, 66.1 0.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 79.9875 5.9804 91.7659 68.2091
129S1/SvImJ m 71.8875 5.9804 83.6659 60.1091
A/J f -12.6812 5.9804 -0.9028 -24.4597
A/J m 11.4875 5.9804 23.2659 -0.2909
C57BL/6J f 58.95 5.9804 70.7284 47.1716
C57BL/6J m 63.525 5.9804 75.3034 51.7466
CAST/EiJ f 45.8158 5.488 56.6244 35.0072
CAST/EiJ m 42.7333 5.6384 53.8381 31.6285
NOD/ShiLtJ f 37.9444 5.6384 49.0492 26.8396
NOD/ShiLtJ m 13.775 5.9804 25.5534 1.9966
NZO/HlLtJ f 14.9062 5.9804 26.6847 3.1278
NZO/HlLtJ m 24.4688 5.9804 36.2472 12.6903
PWK/PhJ f 31.925 5.9804 43.7034 20.1466
PWK/PhJ m 20.9412 5.8019 32.3679 9.5144
WSB/EiJ f 29.5 5.6384 40.6048 18.3952
WSB/EiJ m 37.725 5.9804 49.5034 25.9466


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 75.9375 4.2288 84.2661 67.6089
A/J both -0.5969 4.2288 7.7317 -8.9255
C57BL/6J both 61.2375 4.2288 69.5661 52.9089
CAST/EiJ both 44.2746 3.9341 52.0228 36.5263
NOD/ShiLtJ both 25.8597 4.1096 33.9537 17.7658
NZO/HlLtJ both 19.6875 4.2288 28.0161 11.3589
PWK/PhJ both 26.4331 4.1661 34.6383 18.2279
WSB/EiJ both 33.6125 4.1096 41.7064 25.5186




  GWAS USING LINEAR MIXED MODELS