Project measure / variable:   GMC05   PPI_ISI_5

ID, description, units MPD:55451   PPI_ISI_5   prepulse inhibition (PPI)   [%]  PP2 inter-stimulus interval: 5  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - prepulse inhibition (PPI) PP2 inter-stimulus interval: 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means34.7   % 31.3   %
Median of the strain means30.9   % 25.2   %
SD of the strain means± 25.8 ± 26.2
Coefficient of variation (CV)0.745 0.838
Min–max range of strain means-4.17   –   75.5   % -2.29   –   72.2   %
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 923.3853 923.3853 2.3188 0.1291
strain 7 136689.4524 19527.0646 49.037 < 0.0001
sex:strain 7 16715.4984 2387.9283 5.9966 < 0.0001
Residuals 250 99552.795 398.2112


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 75.5 13.7   16 3.42 0.181 31.4, 86.5 1.58
129S1/SvImJ m 72.2 13.0   16 3.25 0.18 35.1, 85.2 1.56
A/J f -4.17 25.5   16 6.38 -6.12 -48.3, 41.4 -1.5
A/J m 14.3 22.7   16 5.68 1.59 -44.1, 41.8 -0.65
C57BL/6J f 62.6 11.5   16 2.87 0.183 33.2, 81.9 1.08
C57BL/6J m 65.3 10.3   16 2.58 0.158 43.4, 82.9 1.29
CAST/EiJ f 30.4 14.0   19 3.2 0.459 5.5, 58.9 -0.16
CAST/EiJ m 24.4 12.9   18 3.05 0.531 -3.5, 46.6 -0.26
NOD/ShiLtJ f 45.6 18.5   18 4.35 0.405 7.1, 78.7 0.42
NOD/ShiLtJ m 10.7 30.5   16 7.62 2.86 -60.0, 74.1 -0.79
NZO/HlLtJ f 18.9 22.7   16 5.66 1.2 -12.9, 54.5 -0.61
NZO/HlLtJ m 26.0 27.7   16 6.93 1.07 -8.0, 63.6 -0.2
PWK/PhJ f 16.9 20.8   16 5.21 1.23 -13.0, 44.7 -0.69
PWK/PhJ m -2.29 21.4   17 5.18 -9.31 -41.9, 43.9 -1.28
WSB/EiJ f 31.5 20.2   18 4.77 0.642 -33.3, 57.8 -0.12
WSB/EiJ m 40.0 21.7   16 5.42 0.542 -2.0, 68.7 0.33


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 75.5438 4.9888 85.3692 65.7183
129S1/SvImJ m 72.1625 4.9888 81.9879 62.3371
A/J f -4.1687 4.9888 5.6567 -13.9942
A/J m 14.2562 4.9888 24.0817 4.4308
C57BL/6J f 62.5625 4.9888 72.3879 52.7371
C57BL/6J m 65.3312 4.9888 75.1567 55.5058
CAST/EiJ f 30.4 4.578 39.4164 21.3836
CAST/EiJ m 24.3611 4.7035 33.6246 15.0976
NOD/ShiLtJ f 45.5778 4.7035 54.8413 36.3143
NOD/ShiLtJ m 10.675 4.9888 20.5004 0.8496
NZO/HlLtJ f 18.8812 4.9888 28.7067 9.0558
NZO/HlLtJ m 26.0188 4.9888 35.8442 16.1933
PWK/PhJ f 16.9 4.9888 26.7254 7.0746
PWK/PhJ m -2.2941 4.8399 7.238 -11.8262
WSB/EiJ f 31.5278 4.7035 40.7913 22.2643
WSB/EiJ m 39.9688 4.9888 49.7942 30.1433


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 73.8531 3.5276 80.8008 66.9055
A/J both 5.0438 3.5276 11.9914 -1.9039
C57BL/6J both 63.9469 3.5276 70.8945 56.9992
CAST/EiJ both 27.3806 3.2818 33.8441 20.917
NOD/ShiLtJ both 28.1264 3.4282 34.8783 21.3745
NZO/HlLtJ both 22.45 3.5276 29.3976 15.5024
PWK/PhJ both 7.3029 3.4754 14.1476 0.4582
WSB/EiJ both 35.7483 3.4282 42.5002 28.9964




  GWAS USING LINEAR MIXED MODELS