Project measure / variable:   GMC05   ASR_ISI_25

ID, description, units MPD:55442   ASR_ISI_25   acoustic startle response (ASR)   [amplitude]  PP2 inter-stimulus interval: 25  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR) PP2 inter-stimulus interval: 25



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means495   amplitude 583   amplitude
Median of the strain means252   amplitude 384   amplitude
SD of the strain means± 667 ± 636
Coefficient of variation (CV)1.35 1.09
Min–max range of strain means173   –   2136   amplitude 215   –   2140   amplitude
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 590501.18 590501.18 7.4347 0.0069
strain 7 95214777.7228 13602111.1033 171.2565 < 0.0001
sex:strain 7 515858.2972 73694.0425 0.9278 0.4854
Residuals 250 19856338.6534 79425.3546


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 256.0 154.0   16 38.5 0.6 116.0, 704.0 -0.36
129S1/SvImJ m 504.0 260.0   16 65.0 0.516 210.0, 1103.0 -0.12
A/J f 224.0 183.0   16 45.6 0.817 61.6, 824.0 -0.41
A/J m 215.0 99.1   16 24.8 0.461 75.3, 425.0 -0.58
C57BL/6J f 247.0 135.0   16 33.6 0.546 89.1, 581.0 -0.37
C57BL/6J m 448.0 149.0   16 37.3 0.333 218.0, 664.0 -0.21
CAST/EiJ f 237.0 91.4   19 21.0 0.386 115.0, 427.0 -0.39
CAST/EiJ m 350.0 120.0   18 28.2 0.342 160.0, 593.0 -0.37
NOD/ShiLtJ f 173.0 79.6   18 18.8 0.461 83.7, 416.0 -0.48
NOD/ShiLtJ m 253.0 170.0   16 42.5 0.672 130.0, 718.0 -0.52
NZO/HlLtJ f 2136.0 681.0   16 170.0 0.319 1003.0, 3141.0 2.46
NZO/HlLtJ m 2140.0 705.0   16 176.0 0.329 895.0, 3209.0 2.45
PWK/PhJ f 266.0 69.9   16 17.5 0.262 156.0, 361.0 -0.34
PWK/PhJ m 336.0 157.0   17 38.0 0.467 161.0, 835.0 -0.39
WSB/EiJ f 421.0 246.0   18 58.1 0.585 216.0, 1090.0 -0.11
WSB/EiJ m 418.0 159.0   16 39.8 0.381 237.0, 807.0 -0.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 256.3875 70.4563 395.151 117.624
129S1/SvImJ m 503.575 70.4563 642.3385 364.8115
A/J f 223.5062 70.4563 362.2697 84.7428
A/J m 215.0375 70.4563 353.801 76.274
C57BL/6J f 246.6375 70.4563 385.401 107.874
C57BL/6J m 448.3563 70.4563 587.1197 309.5928
CAST/EiJ f 237.1947 64.6551 364.5329 109.8566
CAST/EiJ m 349.8389 66.4268 480.6664 219.0114
NOD/ShiLtJ f 172.6278 66.4268 303.4553 41.8003
NOD/ShiLtJ m 253.2625 70.4563 392.026 114.499
NZO/HlLtJ f 2135.8 70.4563 2274.5635 1997.0365
NZO/HlLtJ m 2139.9 70.4563 2278.6635 2001.1365
PWK/PhJ f 266.3312 70.4563 405.0947 127.5678
PWK/PhJ m 336.2 68.3526 470.8204 201.5796
WSB/EiJ f 420.7556 66.4268 551.583 289.9281
WSB/EiJ m 417.7625 70.4563 556.526 278.999


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 379.9813 49.8201 478.1019 281.8606
A/J both 219.2719 49.8201 317.3925 121.1513
C57BL/6J both 347.4969 49.8201 445.6175 249.3763
CAST/EiJ both 293.5168 46.3487 384.8005 202.2332
NOD/ShiLtJ both 212.9451 48.4164 308.3012 117.589
NZO/HlLtJ both 2137.85 49.8201 2235.9706 2039.7294
PWK/PhJ both 301.2656 49.082 397.9325 204.5987
WSB/EiJ both 419.259 48.4164 514.6151 323.9029




  GWAS USING LINEAR MIXED MODELS