Project measure / variable:   GMC05   PPI_81

ID, description, units MPD:55434   PPI_81   percent prepulse inhibition (PPI), 110 db sound pressure level   [%]  with 81 dB prepulse stimulus  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - percent prepulse inhibition (PPI), 110 db sound pressure level with 81 dB prepulse stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means46.9   % 46.3   %
Median of the strain means49.6   % 41.8   %
SD of the strain means± 26.1 ± 21.1
Coefficient of variation (CV)0.556 0.455
Min–max range of strain means-4.03   –   86.1   % 9.11   –   81.1   %
Mean sample size per strain17.5   mice 17.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 93.43 93.43 0.2419 0.6232
strain 7 122635.4303 17519.3472 45.3667 < 0.0001
sex:strain 7 4816.214 688.0306 1.7817 0.0912
Residuals 261 100790.7925 386.1716


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 86.1 5.26   16 1.31 0.0611 74.3, 92.3 1.5
129S1/SvImJ m 81.1 6.77   16 1.69 0.0835 69.2, 91.1 1.66
A/J f -4.03 29.4   16 7.36 -7.3 -79.0, 26.8 -1.95
A/J m 9.11 29.9   16 7.48 3.28 -38.2, 65.9 -1.76
C57BL/6J f 61.3 9.09   16 2.27 0.148 43.3, 74.0 0.55
C57BL/6J m 64.0 8.59   16 2.15 0.134 47.6, 78.5 0.84
CAST/EiJ f 60.1 7.55   19 1.73 0.126 49.4, 74.7 0.5
CAST/EiJ m 53.5 11.4   18 2.69 0.214 33.3, 78.2 0.34
NOD/ShiLtJ f 46.6 18.5   18 4.36 0.397 9.5, 73.8 -0.01
NOD/ShiLtJ m 42.2 26.6   16 6.66 0.631 5.2, 82.2 -0.19
NZO/HlLtJ f 37.4 16.8   17 4.07 0.449 9.4, 65.3 -0.37
NZO/HlLtJ m 41.3 19.8   17 4.81 0.48 2.7, 64.0 -0.24
PWK/PhJ f 52.6 17.1   20 3.82 0.325 13.1, 74.0 0.22
PWK/PhJ m 37.7 16.6   22 3.54 0.441 -9.0, 62.0 -0.41
WSB/EiJ f 35.4 30.2   18 7.12 0.854 -35.1, 61.9 -0.44
WSB/EiJ m 41.1 30.1   16 7.51 0.732 -22.6, 70.6 -0.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 86.0812 4.9128 95.755 76.4075
129S1/SvImJ m 81.1437 4.9128 90.8175 71.47
A/J f -4.0313 4.9128 5.6425 -13.705
A/J m 9.1125 4.9128 18.7863 -0.5613
C57BL/6J f 61.2562 4.9128 70.93 51.5825
C57BL/6J m 64.0375 4.9128 73.7113 54.3637
CAST/EiJ f 60.0579 4.5083 68.9352 51.1806
CAST/EiJ m 53.4944 4.6318 62.615 44.3739
NOD/ShiLtJ f 46.5833 4.6318 55.7039 37.4628
NOD/ShiLtJ m 42.2125 4.9128 51.8863 32.5387
NZO/HlLtJ f 37.4 4.7661 46.785 28.015
NZO/HlLtJ m 41.3353 4.7661 50.7203 31.9503
PWK/PhJ f 52.555 4.3942 61.2075 43.9025
PWK/PhJ m 37.6909 4.1897 45.9407 29.4411
WSB/EiJ f 35.4111 4.6318 44.5317 26.2906
WSB/EiJ m 41.0875 4.9128 50.7613 31.4137


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 83.6125 3.4739 90.4529 76.7721
A/J both 2.5406 3.4739 9.381 -4.2998
C57BL/6J both 62.6469 3.4739 69.4873 55.8065
CAST/EiJ both 56.7762 3.2318 63.1399 50.4124
NOD/ShiLtJ both 44.3979 3.376 51.0456 37.7502
NZO/HlLtJ both 39.3676 3.3702 46.0038 32.7315
PWK/PhJ both 45.123 3.0357 51.1005 39.1454
WSB/EiJ both 38.2493 3.376 44.897 31.6016




  GWAS USING LINEAR MIXED MODELS