Project measure / variable:   GMC05   ASR_PP_69

ID, description, units MPD:55422   ASR_PP_69   acoustic startle response (ASR), 110 db sound pressure level   [amplitude]  with 69 dB prepulse stimulus  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR), 110 db sound pressure level with 69 dB prepulse stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means505   amplitude 621   amplitude
Median of the strain means292   amplitude 370   amplitude
SD of the strain means± 660 ± 644
Coefficient of variation (CV)1.31 1.04
Min–max range of strain means178   –   2133   amplitude 235   –   2169   amplitude
Mean sample size per strain17.5   mice 17.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 942198.5579 942198.5579 9.5486 0.0022
strain 7 100628990.0302 14375570.0043 145.6882 < 0.0001
sex:strain 7 1089186.2189 155598.0313 1.5769 0.1424
Residuals 261 25753785.1518 98673.5063


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 299.0 168.0   16 42.0 0.562 116.0, 714.0 -0.31
129S1/SvImJ m 679.0 296.0   16 73.9 0.435 224.0, 1170.0 0.09
A/J f 219.0 180.0   16 44.9 0.82 43.4, 794.0 -0.43
A/J m 256.0 136.0   16 33.9 0.53 84.3, 567.0 -0.57
C57BL/6J f 302.0 175.0   16 43.7 0.58 131.0, 770.0 -0.31
C57BL/6J m 582.0 223.0   16 55.6 0.383 313.0, 1095.0 -0.06
CAST/EiJ f 255.0 94.5   19 21.7 0.37 128.0, 433.0 -0.38
CAST/EiJ m 358.0 132.0   18 31.1 0.369 171.0, 694.0 -0.41
NOD/ShiLtJ f 178.0 80.8   18 19.0 0.454 103.0, 373.0 -0.5
NOD/ShiLtJ m 235.0 156.0   16 39.0 0.662 115.0, 666.0 -0.6
NZO/HlLtJ f 2133.0 719.0   17 174.0 0.337 954.0, 3143.0 2.47
NZO/HlLtJ m 2169.0 866.0   17 210.0 0.399 507.0, 3306.0 2.4
PWK/PhJ f 286.0 90.5   20 20.2 0.317 183.0, 494.0 -0.33
PWK/PhJ m 309.0 113.0   22 24.0 0.364 158.0, 621.0 -0.48
WSB/EiJ f 369.0 135.0   18 31.8 0.366 222.0, 730.0 -0.21
WSB/EiJ m 382.0 94.7   16 23.7 0.248 264.0, 592.0 -0.37


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 298.5375 78.5308 453.1722 143.9028
129S1/SvImJ m 679.1062 78.5308 833.7409 524.4716
A/J f 219.1125 78.5308 373.7472 64.4778
A/J m 255.725 78.5308 410.3597 101.0903
C57BL/6J f 301.6562 78.5308 456.2909 147.0216
C57BL/6J m 581.7187 78.5308 736.3534 427.0841
CAST/EiJ f 255.2053 72.0648 397.1078 113.3027
CAST/EiJ m 358.3889 74.0396 504.1799 212.5979
NOD/ShiLtJ f 177.9111 74.0396 323.7021 32.1201
NOD/ShiLtJ m 235.3375 78.5308 389.9722 80.7028
NZO/HlLtJ f 2132.8059 76.1861 2282.8236 1982.7882
NZO/HlLtJ m 2168.9882 76.1861 2319.0059 2018.9706
PWK/PhJ f 285.52 70.2401 423.8295 147.2105
PWK/PhJ m 309.2955 66.9713 441.1684 177.4226
WSB/EiJ f 369.3833 74.0396 515.1743 223.5924
WSB/EiJ m 381.5375 78.5308 536.1722 226.9028


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 488.8219 55.5297 598.1651 379.4786
A/J both 237.4187 55.5297 346.762 128.0755
C57BL/6J both 441.6875 55.5297 551.0307 332.3443
CAST/EiJ both 306.7971 51.6604 408.5214 205.0728
NOD/ShiLtJ both 206.6243 53.9652 312.8868 100.3618
NZO/HlLtJ both 2150.8971 53.8717 2256.9756 2044.8185
PWK/PhJ both 297.4077 48.5253 392.9587 201.8567
WSB/EiJ both 375.4604 53.9652 481.7229 269.1979




  GWAS USING LINEAR MIXED MODELS