Project measure / variable:   GMC05   ASR_PP_67

ID, description, units MPD:55421   ASR_PP_67   acoustic startle response (ASR), 110 db sound pressure level   [amplitude]  with 67 dB prepulse stimulus  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR), 110 db sound pressure level with 67 dB prepulse stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means544   amplitude 677   amplitude
Median of the strain means310   amplitude 400   amplitude
SD of the strain means± 667 ± 651
Coefficient of variation (CV)1.22 0.962
Min–max range of strain means205   –   2179   amplitude 202   –   2188   amplitude
Mean sample size per strain17.5   mice 17.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1203366.6083 1203366.6083 11.5658 0.0008
strain 7 101471469.2403 14495924.1772 139.3235 < 0.0001
sex:strain 7 2250628.0791 321518.297 3.0902 0.0038
Residuals 261 27155764.4854 104045.0747


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 397.0 211.0   16 52.6 0.531 112.0, 927.0 -0.22
129S1/SvImJ m 892.0 375.0   16 93.8 0.42 400.0, 1653.0 0.33
A/J f 229.0 247.0   16 61.7 1.08 52.4, 1091.0 -0.47
A/J m 202.0 83.5   16 20.9 0.413 95.5, 379.0 -0.73
C57BL/6J f 323.0 195.0   16 48.8 0.604 104.0, 776.0 -0.33
C57BL/6J m 690.0 223.0   16 55.8 0.324 352.0, 1110.0 0.02
CAST/EiJ f 247.0 81.6   19 18.7 0.33 135.0, 382.0 -0.45
CAST/EiJ m 386.0 150.0   18 35.2 0.387 193.0, 633.0 -0.45
NOD/ShiLtJ f 205.0 89.3   18 21.0 0.436 77.4, 395.0 -0.51
NOD/ShiLtJ m 301.0 222.0   16 55.4 0.737 162.0, 981.0 -0.58
NZO/HlLtJ f 2179.0 705.0   17 171.0 0.324 929.0, 3486.0 2.45
NZO/HlLtJ m 2188.0 818.0   17 198.0 0.374 594.0, 3309.0 2.32
PWK/PhJ f 297.0 62.6   20 14.0 0.211 220.0, 424.0 -0.37
PWK/PhJ m 341.0 121.0   22 25.7 0.353 170.0, 679.0 -0.52
WSB/EiJ f 479.0 300.0   18 70.6 0.626 216.0, 1278.0 -0.1
WSB/EiJ m 413.0 89.9   16 22.5 0.218 282.0, 588.0 -0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 396.8063 80.64 555.5941 238.0184
129S1/SvImJ m 892.3875 80.64 1051.1754 733.5996
A/J f 229.375 80.64 388.1629 70.5871
A/J m 202.1937 80.64 360.9816 43.4059
C57BL/6J f 323.15 80.64 481.9379 164.3621
C57BL/6J m 689.6938 80.64 848.4816 530.9059
CAST/EiJ f 247.2684 74.0004 392.9822 101.5547
CAST/EiJ m 386.3 76.0282 536.0067 236.5933
NOD/ShiLtJ f 204.7722 76.0282 354.4789 55.0656
NOD/ShiLtJ m 300.9125 80.64 459.7004 142.1246
NZO/HlLtJ f 2179.3118 78.2323 2333.3586 2025.2649
NZO/HlLtJ m 2187.6412 78.2323 2341.6881 2033.5943
PWK/PhJ f 296.93 72.1267 438.9542 154.9058
PWK/PhJ m 341.3591 68.7701 476.7739 205.9443
WSB/EiJ f 478.6778 76.0282 628.3844 328.9711
WSB/EiJ m 413.125 80.64 571.9129 254.3371


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 644.5969 57.0211 756.8769 532.3169
A/J both 215.7844 57.0211 328.0644 103.5044
C57BL/6J both 506.4219 57.0211 618.7019 394.1419
CAST/EiJ both 316.7842 53.0479 421.2406 212.3278
NOD/ShiLtJ both 252.8424 55.4146 361.9589 143.7258
NZO/HlLtJ both 2183.4765 55.3186 2292.4041 2074.5489
PWK/PhJ both 319.1445 49.8286 417.2619 221.0272
WSB/EiJ both 445.9014 55.4146 555.0179 336.7848




  GWAS USING LINEAR MIXED MODELS