Project measure / variable:   GMC05   ASR_120

ID, description, units MPD:55418   ASR_120   acoustic startle response (ASR)   [amplitude]  evoked by 120 dB  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR) evoked by 120 dB



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means843   amplitude 1038   amplitude
Median of the strain means524   amplitude 666   amplitude
SD of the strain means± 797 ± 900
Coefficient of variation (CV)0.946 0.866
Min–max range of strain means328   –   2620   amplitude 250   –   2860   amplitude
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2780450.3461 2780450.3461 42.2314 < 0.0001
strain 7 160854208.1594 22979172.5942 349.0232 < 0.0001
sex:strain 7 2744499.2779 392071.3254 5.955 < 0.0001
Residuals 250 16459629.5602 65838.5182


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1393.0 255.0   16 63.6 0.183 904.0, 1870.0 0.69
129S1/SvImJ m 1835.0 317.0   16 79.2 0.173 1328.0, 2337.0 0.89
A/J f 328.0 275.0   16 68.9 0.84 74.2, 1213.0 -0.65
A/J m 250.0 173.0   16 43.3 0.693 94.7, 759.0 -0.88
C57BL/6J f 620.0 320.0   16 80.0 0.516 252.0, 1437.0 -0.28
C57BL/6J m 1204.0 353.0   16 88.2 0.293 593.0, 1826.0 0.18
CAST/EiJ f 441.0 96.9   19 22.2 0.22 285.0, 647.0 -0.5
CAST/EiJ m 617.0 161.0   18 37.9 0.261 365.0, 957.0 -0.47
NOD/ShiLtJ f 330.0 152.0   18 35.9 0.461 78.0, 632.0 -0.64
NOD/ShiLtJ m 379.0 246.0   16 61.6 0.65 178.0, 1090.0 -0.73
NZO/HlLtJ f 2620.0 458.0   16 114.0 0.175 1722.0, 3369.0 2.23
NZO/HlLtJ m 2860.0 413.0   16 103.0 0.144 2054.0, 3398.0 2.02
PWK/PhJ f 406.0 107.0   16 26.8 0.264 269.0, 678.0 -0.55
PWK/PhJ m 447.0 128.0   17 30.9 0.285 293.0, 743.0 -0.66
WSB/EiJ f 606.0 134.0   18 31.5 0.221 290.0, 788.0 -0.3
WSB/EiJ m 716.0 208.0   16 52.0 0.291 277.0, 1060.0 -0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1393.4813 64.1475 1519.8197 1267.1428
129S1/SvImJ m 1834.8437 64.1475 1961.1822 1708.5053
A/J f 327.7938 64.1475 454.1322 201.4553
A/J m 249.85 64.1475 376.1885 123.5115
C57BL/6J f 620.375 64.1475 746.7135 494.0365
C57BL/6J m 1203.7375 64.1475 1330.076 1077.399
CAST/EiJ f 440.6526 58.8658 556.5888 324.7165
CAST/EiJ m 617.2444 60.4789 736.3575 498.1314
NOD/ShiLtJ f 329.7889 60.4789 448.902 210.6758
NOD/ShiLtJ m 379.0 64.1475 505.3385 252.6615
NZO/HlLtJ f 2620.0313 64.1475 2746.3697 2493.6928
NZO/HlLtJ m 2859.925 64.1475 2986.2635 2733.5865
PWK/PhJ f 406.2625 64.1475 532.601 279.924
PWK/PhJ m 447.0765 62.2323 569.6428 324.5101
WSB/EiJ f 606.3667 60.4789 725.4797 487.2536
WSB/EiJ m 716.2125 64.1475 842.551 589.874


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1614.1625 45.3592 1703.4973 1524.8277
A/J both 288.8219 45.3592 378.1567 199.4871
C57BL/6J both 912.0563 45.3592 1001.391 822.7215
CAST/EiJ both 528.9485 42.1986 612.0586 445.8385
NOD/ShiLtJ both 354.3944 44.0812 441.2123 267.5766
NZO/HlLtJ both 2739.9781 45.3592 2829.3129 2650.6433
PWK/PhJ both 426.6695 44.6871 514.6807 338.6582
WSB/EiJ both 661.2896 44.0812 748.1074 574.4718




  GWAS USING LINEAR MIXED MODELS