Project measure / variable:   GMC05   ASR_110

ID, description, units MPD:55417   ASR_110   acoustic startle response (ASR)   [amplitude]  evoked by 110 dB  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR) evoked by 110 dB



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means801   amplitude 1007   amplitude
Median of the strain means532   amplitude 672   amplitude
SD of the strain means± 751 ± 859
Coefficient of variation (CV)0.937 0.853
Min–max range of strain means208   –   2465   amplitude 254   –   2695   amplitude
Mean sample size per strain17.5   mice 17.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2831425.0156 2831425.0156 36.0044 < 0.0001
strain 7 151791826.6064 21684546.6581 275.7408 < 0.0001
sex:strain 7 3308702.4803 472671.7829 6.0105 < 0.0001
Residuals 261 20525313.3687 78641.0474


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1303.0 259.0   16 64.7 0.199 786.0, 1800.0 0.67
129S1/SvImJ m 1781.0 349.0   16 87.3 0.196 1072.0, 2348.0 0.9
A/J f 208.0 180.0   16 45.0 0.867 69.5, 798.0 -0.79
A/J m 254.0 124.0   16 31.0 0.488 88.2, 506.0 -0.88
C57BL/6J f 623.0 327.0   16 81.7 0.525 236.0, 1431.0 -0.24
C57BL/6J m 1262.0 341.0   16 85.2 0.27 580.0, 1828.0 0.3
CAST/EiJ f 439.0 106.0   19 24.4 0.242 266.0, 676.0 -0.48
CAST/EiJ m 610.0 124.0   18 29.2 0.203 409.0, 830.0 -0.46
NOD/ShiLtJ f 299.0 127.0   18 30.0 0.425 110.0, 521.0 -0.67
NOD/ShiLtJ m 305.0 207.0   16 51.8 0.679 142.0, 924.0 -0.82
NZO/HlLtJ f 2465.0 485.0   17 118.0 0.197 1643.0, 3212.0 2.22
NZO/HlLtJ m 2695.0 662.0   17 161.0 0.246 534.0, 3354.0 1.97
PWK/PhJ f 442.0 116.0   20 25.9 0.263 280.0, 717.0 -0.48
PWK/PhJ m 412.0 115.0   22 24.4 0.278 250.0, 692.0 -0.69
WSB/EiJ f 629.0 159.0   18 37.4 0.252 259.0, 869.0 -0.23
WSB/EiJ m 734.0 181.0   16 45.3 0.247 405.0, 1006.0 -0.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1302.7312 70.1075 1440.7796 1164.6829
129S1/SvImJ m 1781.0812 70.1075 1919.1296 1643.0329
A/J f 207.7625 70.1075 345.8109 69.7141
A/J m 254.1875 70.1075 392.2359 116.1391
C57BL/6J f 622.7062 70.1075 760.7546 484.6579
C57BL/6J m 1261.5562 70.1075 1399.6046 1123.5079
CAST/EiJ f 438.6263 64.3351 565.3082 311.9444
CAST/EiJ m 609.9556 66.098 740.1088 479.8023
NOD/ShiLtJ f 299.2111 66.098 429.3644 169.0579
NOD/ShiLtJ m 305.325 70.1075 443.3734 167.2766
NZO/HlLtJ f 2464.5059 68.0143 2598.4325 2330.5793
NZO/HlLtJ m 2695.3471 68.0143 2829.2736 2561.4205
PWK/PhJ f 441.62 62.7061 565.0942 318.1458
PWK/PhJ m 412.3545 59.7879 530.0826 294.6265
WSB/EiJ f 629.0444 66.098 759.1977 498.8912
WSB/EiJ m 734.0687 70.1075 872.1171 596.0204


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1541.9062 49.5735 1639.5212 1444.2913
A/J both 230.975 49.5735 328.5899 133.3601
C57BL/6J both 942.1312 49.5735 1039.7462 844.5163
CAST/EiJ both 524.2909 46.1193 615.1042 433.4777
NOD/ShiLtJ both 302.2681 48.1768 397.1327 207.4034
NZO/HlLtJ both 2579.9265 48.0934 2674.6269 2485.2261
PWK/PhJ both 426.9873 43.3204 512.2893 341.6852
WSB/EiJ both 681.5566 48.1768 776.4213 586.6919




  GWAS USING LINEAR MIXED MODELS