Project measure / variable:   GMC05   ASR_90

ID, description, units MPD:55415   ASR_90   acoustic startle response (ASR)   [amplitude]  evoked by 90 dB  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR) evoked by 90 dB



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means327   amplitude 430   amplitude
Median of the strain means273   amplitude 338   amplitude
SD of the strain means± 253 ± 338
Coefficient of variation (CV)0.774 0.787
Min–max range of strain means70.7   –   834   amplitude 62.8   –   1018   amplitude
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 681730.8564 681730.8564 18.0425 < 0.0001
strain 7 19092150.7875 2727450.1125 72.1839 < 0.0001
sex:strain 7 1320948.0094 188706.8585 4.9943 < 0.0001
Residuals 250 9446191.4406 37784.7658


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 413.0 220.0   16 54.9 0.531 190.0, 982.0 0.34
129S1/SvImJ m 584.0 222.0   16 55.5 0.38 248.0, 1143.0 0.45
A/J f 70.7 21.9   16 5.48 0.31 49.7, 140.0 -1.01
A/J m 62.8 16.6   16 4.16 0.265 38.4, 95.4 -1.09
C57BL/6J f 326.0 152.0   16 37.9 0.465 190.0, 791.0 0.0
C57BL/6J m 748.0 222.0   16 55.5 0.297 312.0, 1123.0 0.94
CAST/EiJ f 104.0 30.5   19 7.0 0.295 54.2, 151.0 -0.88
CAST/EiJ m 172.0 59.0   18 13.9 0.344 87.9, 282.0 -0.76
NOD/ShiLtJ f 220.0 135.0   18 31.9 0.614 61.0, 613.0 -0.42
NOD/ShiLtJ m 181.0 142.0   16 35.4 0.785 52.7, 641.0 -0.74
NZO/HlLtJ f 834.0 355.0   16 88.8 0.426 405.0, 1534.0 2.0
NZO/HlLtJ m 1018.0 481.0   16 120.0 0.472 214.0, 1956.0 1.74
PWK/PhJ f 156.0 24.7   16 6.17 0.158 119.0, 213.0 -0.68
PWK/PhJ m 179.0 38.1   17 9.24 0.213 109.0, 274.0 -0.74
WSB/EiJ f 492.0 169.0   18 39.9 0.344 223.0, 1026.0 0.65
WSB/EiJ m 496.0 145.0   16 36.2 0.292 276.0, 723.0 0.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 413.475 48.5958 509.1843 317.7657
129S1/SvImJ m 584.0562 48.5958 679.7655 488.347
A/J f 70.6563 48.5958 166.3655 -25.053
A/J m 62.8125 48.5958 158.5218 -32.8968
C57BL/6J f 326.1 48.5958 421.8093 230.3907
C57BL/6J m 747.8875 48.5958 843.5968 652.1782
CAST/EiJ f 103.5421 44.5945 191.371 15.7133
CAST/EiJ m 171.7722 45.8165 262.0078 81.5367
NOD/ShiLtJ f 220.4 45.8165 310.6356 130.1644
NOD/ShiLtJ m 180.55 48.5958 276.2593 84.8407
NZO/HlLtJ f 833.8438 48.5958 929.553 738.1345
NZO/HlLtJ m 1018.4375 48.5958 1114.1468 922.7282
PWK/PhJ f 156.35 48.5958 252.0593 60.6407
PWK/PhJ m 179.1235 47.1448 271.9752 86.2719
WSB/EiJ f 491.9944 45.8165 582.23 401.7589
WSB/EiJ m 495.8625 48.5958 591.5718 400.1532


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 498.7656 34.3624 566.4423 431.089
A/J both 66.7344 34.3624 134.411 -0.9423
C57BL/6J both 536.9937 34.3624 604.6704 469.3171
CAST/EiJ both 137.6572 31.9681 200.6182 74.6961
NOD/ShiLtJ both 200.475 33.3942 266.2449 134.7051
NZO/HlLtJ both 926.1406 34.3624 993.8173 858.464
PWK/PhJ both 167.7368 33.8533 234.4108 101.0628
WSB/EiJ both 493.9285 33.3942 559.6984 428.1586




  GWAS USING LINEAR MIXED MODELS