Project measure / variable:   GMC05   ASR_85

ID, description, units MPD:55414   ASR_85   acoustic startle response (ASR)   [amplitude]  evoked by 85 dB  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR) evoked by 85 dB



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means201   amplitude 270   amplitude
Median of the strain means183   amplitude 263   amplitude
SD of the strain means± 122 ± 165
Coefficient of variation (CV)0.607 0.612
Min–max range of strain means60.1   –   417   amplitude 64.2   –   475   amplitude
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 285788.1175 285788.1175 13.2081 0.0003
strain 7 4429870.6182 632838.6597 29.2476 < 0.0001
sex:strain 7 523316.1374 74759.4482 3.4551 0.0015
Residuals 250 5409317.5686 21637.2703


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 249.0 124.0   16 31.1 0.499 132.0, 663.0 0.39
129S1/SvImJ m 354.0 159.0   16 39.8 0.449 140.0, 744.0 0.51
A/J f 60.1 15.9   16 3.98 0.265 40.0, 106.0 -1.16
A/J m 64.2 18.3   16 4.57 0.285 36.0, 103.0 -1.24
C57BL/6J f 191.0 51.2   16 12.8 0.268 120.0, 349.0 -0.08
C57BL/6J m 441.0 183.0   16 45.8 0.415 185.0, 801.0 1.03
CAST/EiJ f 65.4 17.2   19 3.94 0.263 29.0, 97.4 -1.11
CAST/EiJ m 94.4 24.8   18 5.84 0.262 63.2, 153.0 -1.06
NOD/ShiLtJ f 175.0 87.2   18 20.5 0.499 68.1, 378.0 -0.22
NOD/ShiLtJ m 157.0 117.0   16 29.2 0.744 66.4, 520.0 -0.68
NZO/HlLtJ f 314.0 238.0   16 59.6 0.76 114.0, 914.0 0.92
NZO/HlLtJ m 475.0 387.0   16 96.8 0.816 39.0, 1251.0 1.24
PWK/PhJ f 139.0 30.1   16 7.52 0.217 105.0, 204.0 -0.51
PWK/PhJ m 172.0 42.9   17 10.4 0.249 99.4, 285.0 -0.59
WSB/EiJ f 417.0 169.0   18 39.8 0.405 223.0, 947.0 1.76
WSB/EiJ m 402.0 133.0   16 33.2 0.33 224.0, 783.0 0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 249.4875 36.774 321.9139 177.0611
129S1/SvImJ m 354.4813 36.774 426.9076 282.0549
A/J f 60.15 36.774 132.5764 -12.2764
A/J m 64.1563 36.774 136.5826 -8.2701
C57BL/6J f 190.825 36.774 263.2514 118.3986
C57BL/6J m 441.175 36.774 513.6014 368.7486
CAST/EiJ f 65.3684 33.7462 131.8314 -1.0946
CAST/EiJ m 94.4444 34.6709 162.7287 26.1602
NOD/ShiLtJ f 174.8333 34.6709 243.1176 106.5491
NOD/ShiLtJ m 156.9438 36.774 229.3701 84.5174
NZO/HlLtJ f 313.7188 36.774 386.1451 241.2924
NZO/HlLtJ m 474.675 36.774 547.1014 402.2486
PWK/PhJ f 138.7 36.774 211.1264 66.2736
PWK/PhJ m 172.4412 35.6761 242.7051 102.1773
WSB/EiJ f 417.0056 34.6709 485.2898 348.7213
WSB/EiJ m 401.9625 36.774 474.3889 329.5361


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 301.9844 26.0032 353.1976 250.7712
A/J both 62.1531 26.0032 113.3663 10.9399
C57BL/6J both 316.0 26.0032 367.2132 264.7868
CAST/EiJ both 79.9064 24.1913 127.5511 32.2617
NOD/ShiLtJ both 165.8885 25.2705 215.6588 116.1183
NZO/HlLtJ both 394.1969 26.0032 445.4101 342.9837
PWK/PhJ both 155.5706 25.6179 206.025 105.1161
WSB/EiJ both 409.484 25.2705 459.2543 359.7137




  GWAS USING LINEAR MIXED MODELS