Project measure / variable:   GMC05   ASR_80

ID, description, units MPD:55413   ASR_80   acoustic startle response (ASR)   [amplitude]  evoked by 80 dB  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR) evoked by 80 dB



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means150   amplitude 202   amplitude
Median of the strain means129   amplitude 210   amplitude
SD of the strain means± 85.9 ± 107
Coefficient of variation (CV)0.574 0.531
Min–max range of strain means55.8   –   322   amplitude 61.3   –   336   amplitude
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 167753.5938 167753.5938 12.8057 0.0004
strain 7 2021108.3981 288729.7712 22.0406 < 0.0001
sex:strain 7 212559.9449 30365.7064 2.318 0.0263
Residuals 250 3274981.1848 13099.9247


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 210.0 105.0   16 26.3 0.5 113.0, 524.0 0.7
129S1/SvImJ m 261.0 128.0   16 32.0 0.491 101.0, 602.0 0.55
A/J f 62.9 18.7   16 4.68 0.297 45.8, 124.0 -1.01
A/J m 61.3 13.2   16 3.31 0.216 37.3, 91.7 -1.31
C57BL/6J f 134.0 38.1   16 9.53 0.285 75.9, 226.0 -0.18
C57BL/6J m 254.0 107.0   16 26.7 0.42 104.0, 454.0 0.48
CAST/EiJ f 55.8 17.9   19 4.11 0.322 28.9, 102.0 -1.09
CAST/EiJ m 84.1 24.8   18 5.85 0.295 46.9, 154.0 -1.1
NOD/ShiLtJ f 124.0 61.2   18 14.4 0.491 62.8, 288.0 -0.3
NOD/ShiLtJ m 128.0 36.3   16 9.07 0.284 97.6, 220.0 -0.69
NZO/HlLtJ f 167.0 165.0   16 41.3 0.988 33.2, 523.0 0.2
NZO/HlLtJ m 336.0 329.0   16 82.2 0.98 38.8, 1038.0 1.24
PWK/PhJ f 122.0 26.7   16 6.67 0.218 77.2, 169.0 -0.32
PWK/PhJ m 165.0 40.9   17 9.91 0.247 106.0, 246.0 -0.35
WSB/EiJ f 322.0 129.0   18 30.4 0.4 118.0, 654.0 2.01
WSB/EiJ m 329.0 118.0   16 29.6 0.36 197.0, 610.0 1.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 210.2188 28.6137 266.5734 153.8641
129S1/SvImJ m 260.8688 28.6137 317.2234 204.5141
A/J f 62.9125 28.6137 119.2672 6.5578
A/J m 61.2688 28.6137 117.6234 4.9141
C57BL/6J f 133.7125 28.6137 190.0672 77.3578
C57BL/6J m 254.15 28.6137 310.5047 197.7953
CAST/EiJ f 55.7526 26.2578 107.4672 4.038
CAST/EiJ m 84.1167 26.9773 137.2484 30.985
NOD/ShiLtJ f 124.4611 26.9773 177.5928 71.3294
NOD/ShiLtJ m 127.6937 28.6137 184.0484 71.3391
NZO/HlLtJ f 167.075 28.6137 223.4297 110.7203
NZO/HlLtJ m 335.6062 28.6137 391.9609 279.2516
PWK/PhJ f 122.225 28.6137 178.5797 65.8703
PWK/PhJ m 165.3235 27.7594 219.9956 110.6515
WSB/EiJ f 322.1389 26.9773 375.2706 269.0072
WSB/EiJ m 328.6937 28.6137 385.0484 272.3391


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 235.5438 20.233 275.3925 195.695
A/J both 62.0906 20.233 101.9394 22.2418
C57BL/6J both 193.9313 20.233 233.78 154.0825
CAST/EiJ both 69.9346 18.8231 107.0068 32.8625
NOD/ShiLtJ both 126.0774 19.6629 164.8035 87.3514
NZO/HlLtJ both 251.3406 20.233 291.1894 211.4918
PWK/PhJ both 143.7743 19.9332 183.0327 104.5159
WSB/EiJ both 325.4163 19.6629 364.1424 286.6903




  GWAS USING LINEAR MIXED MODELS