Project measure / variable:   GMC05   ASR_70

ID, description, units MPD:55412   ASR_70   acoustic startle response (ASR)   [amplitude]  evoked by 70 dB  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR) evoked by 70 dB



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means113   amplitude 134   amplitude
Median of the strain means100   amplitude 118   amplitude
SD of the strain means± 61.3 ± 61.9
Coefficient of variation (CV)0.541 0.463
Min–max range of strain means47.6   –   245   amplitude 64.4   –   231   amplitude
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 24539.3706 24539.3706 2.7297 0.0998
strain 7 838828.1701 119832.5957 13.33 < 0.0001
sex:strain 7 71670.2887 10238.6127 1.1389 0.3392
Residuals 250 2247422.0705 8989.6883


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 100.0 29.7   16 7.43 0.296 51.6, 161.0 -0.22
129S1/SvImJ m 120.0 47.7   16 11.9 0.397 48.4, 184.0 -0.22
A/J f 60.1 12.0   16 3.01 0.201 41.9, 81.0 -0.87
A/J m 64.4 15.4   16 3.84 0.238 43.0, 105.0 -1.12
C57BL/6J f 100.0 29.6   16 7.4 0.295 63.2, 148.0 -0.22
C57BL/6J m 116.0 29.7   16 7.42 0.256 70.3, 169.0 -0.29
CAST/EiJ f 47.6 17.9   19 4.1 0.375 22.1, 81.9 -1.07
CAST/EiJ m 68.6 28.0   18 6.59 0.407 34.1, 127.0 -1.05
NOD/ShiLtJ f 94.8 34.7   18 8.17 0.366 49.5, 188.0 -0.3
NOD/ShiLtJ m 97.6 30.7   16 7.67 0.314 44.3, 156.0 -0.58
NZO/HlLtJ f 147.0 171.0   16 42.8 1.16 25.3, 626.0 0.55
NZO/HlLtJ m 231.0 194.0   16 48.6 0.84 31.0, 600.0 1.57
PWK/PhJ f 112.0 26.1   16 6.54 0.233 72.2, 167.0 -0.02
PWK/PhJ m 163.0 26.8   17 6.51 0.165 119.0, 234.0 0.47
WSB/EiJ f 245.0 222.0   18 52.4 0.907 86.5, 858.0 2.15
WSB/EiJ m 209.0 128.0   16 32.0 0.612 84.6, 498.0 1.22


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 100.4875 23.7035 147.1715 53.8035
129S1/SvImJ m 120.1562 23.7035 166.8402 73.4723
A/J f 60.0813 23.7035 106.7652 13.3973
A/J m 64.4313 23.7035 111.1152 17.7473
C57BL/6J f 100.3125 23.7035 146.9965 53.6285
C57BL/6J m 115.825 23.7035 162.509 69.141
CAST/EiJ f 47.5842 21.7518 90.4244 4.744
CAST/EiJ m 68.6111 22.3479 112.6252 24.597
NOD/ShiLtJ f 94.8056 22.3479 138.8196 50.7915
NOD/ShiLtJ m 97.5688 23.7035 144.2527 50.8848
NZO/HlLtJ f 147.475 23.7035 194.159 100.791
NZO/HlLtJ m 231.3375 23.7035 278.0215 184.6535
PWK/PhJ f 112.275 23.7035 158.959 65.591
PWK/PhJ m 162.7941 22.9958 208.0842 117.504
WSB/EiJ f 245.2278 22.3479 289.2419 201.2137
WSB/EiJ m 209.0625 23.7035 255.7465 162.3785


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 110.3219 16.7609 143.3324 77.3113
A/J both 62.2563 16.7609 95.2668 29.2457
C57BL/6J both 108.0688 16.7609 141.0793 75.0582
CAST/EiJ both 58.0977 15.593 88.8081 27.3872
NOD/ShiLtJ both 96.1872 16.2887 128.2677 64.1066
NZO/HlLtJ both 189.4063 16.7609 222.4168 156.3957
PWK/PhJ both 137.5346 16.5126 170.0561 105.0131
WSB/EiJ both 227.1451 16.2887 259.2256 195.0646




  GWAS USING LINEAR MIXED MODELS