Project measure / variable:   GMC05   ASR_bn

ID, description, units MPD:55411   ASR_bn   acoustic startle response (ASR)   [amplitude]  evoked by background noise  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR) evoked by background noise



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means93.6   amplitude 88.2   amplitude
Median of the strain means63.1   amplitude 64.8   amplitude
SD of the strain means± 86.3 ± 53.2
Coefficient of variation (CV)0.922 0.603
Min–max range of strain means36.1   –   300   amplitude 31.7   –   182   amplitude
Mean sample size per strain17.5   mice 17.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2086.0693 2086.0693 0.0841 0.7721
strain 7 1120474.8385 160067.8341 6.451 < 0.0001
sex:strain 7 149389.109 21341.3013 0.8601 0.5387
Residuals 261 6476195.9472 24813.0113


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 36.1 11.2   16 2.81 0.311 24.1, 62.6 -0.67
129S1/SvImJ m 31.7 9.33   16 2.33 0.294 18.8, 47.9 -1.06
A/J f 61.5 22.1   16 5.53 0.359 40.9, 106.0 -0.37
A/J m 66.6 26.9   16 6.72 0.403 41.1, 139.0 -0.41
C57BL/6J f 44.8 20.7   16 5.16 0.461 18.6, 79.8 -0.57
C57BL/6J m 55.1 14.7   16 3.67 0.267 33.5, 75.3 -0.62
CAST/EiJ f 49.2 19.9   19 4.56 0.404 21.9, 86.2 -0.51
CAST/EiJ m 47.5 21.5   18 5.06 0.451 19.4, 98.7 -0.77
NOD/ShiLtJ f 99.9 33.4   18 7.87 0.334 45.4, 188.0 0.07
NOD/ShiLtJ m 114.0 33.5   16 8.37 0.295 67.2, 176.0 0.48
NZO/HlLtJ f 64.7 26.8   17 6.49 0.414 18.7, 118.0 -0.34
NZO/HlLtJ m 63.1 26.3   17 6.38 0.417 22.1, 131.0 -0.47
PWK/PhJ f 92.8 35.5   20 7.94 0.383 34.5, 143.0 -0.01
PWK/PhJ m 146.0 37.7   22 8.04 0.258 69.0, 253.0 1.08
WSB/EiJ f 300.0 553.0   18 130.0 1.84 22.6, 1850.0 2.39
WSB/EiJ m 182.0 272.0   16 68.1 1.49 20.8, 671.0 1.76


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 36.1437 39.3804 113.6874 -41.3999
129S1/SvImJ m 31.7 39.3804 109.2437 -45.8437
A/J f 61.5063 39.3804 139.0499 -16.0374
A/J m 66.65 39.3804 144.1937 -10.8937
C57BL/6J f 44.7687 39.3804 122.3124 -32.7749
C57BL/6J m 55.0625 39.3804 132.6062 -22.4812
CAST/EiJ f 49.2 36.1379 120.359 -21.959
CAST/EiJ m 47.5333 37.1282 120.6422 -25.5755
NOD/ShiLtJ f 99.9222 37.1282 173.0311 26.8133
NOD/ShiLtJ m 113.5062 39.3804 191.0499 35.9626
NZO/HlLtJ f 64.7059 38.2046 139.9343 -10.5225
NZO/HlLtJ m 63.0882 38.2046 138.3166 -12.1402
PWK/PhJ f 92.78 35.2229 162.1372 23.4228
PWK/PhJ m 146.2091 33.5837 212.3386 80.0796
WSB/EiJ f 300.2056 37.1282 373.3144 227.0967
WSB/EiJ m 182.3438 39.3804 259.8874 104.8001


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 33.9219 27.8461 88.7535 -20.9098
A/J both 64.0781 27.8461 118.9098 9.2465
C57BL/6J both 49.9156 27.8461 104.7473 -4.916
CAST/EiJ both 48.3667 25.9058 99.3777 -2.6444
NOD/ShiLtJ both 106.7142 27.0616 160.001 53.4274
NZO/HlLtJ both 63.8971 27.0147 117.0916 10.7025
PWK/PhJ both 119.4945 24.3337 167.4099 71.5792
WSB/EiJ both 241.2747 27.0616 294.5614 187.9879




  GWAS USING LINEAR MIXED MODELS