Project measure / variable:   GMC04   LatFall_2

ID, description, units MPD:55312   LatFall_2   latency to fall from accelerating rotarod (8rpm/min)   [s]  trial2  
Data set, strains GMC04   inbred w/CC7   7 strains     sex: both     age: 9-10wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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GMC04 - latency to fall from accelerating rotarod (8rpm/min) trial2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means153   s 152   s
Median of the strain means163   s 173   s
SD of the strain means± 36.9 ± 38.6
Coefficient of variation (CV)0.242 0.254
Min–max range of strain means86.7   –   192   s 77.4   –   189   s
Mean sample size per strain17.4   mice 17.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 40.4419 40.4419 0.0055 0.941
strain 6 277527.6993 46254.6166 6.2879 < 0.0001
sex:strain 6 11538.5123 1923.0854 0.2614 0.9542
Residuals 228 1677208.0118 7356.1755


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 119.0 48.2   16 12.1 0.405 56.0, 235.0 -0.91
129S1/SvImJ m 137.0 44.5   16 11.1 0.326 69.0, 237.0 -0.39
A/J f 86.7 21.4   16 5.34 0.246 52.0, 120.0 -1.79
A/J m 77.4 41.4   16 10.3 0.535 20.0, 133.0 -1.93
C57BL/6J f 181.0 69.6   16 17.4 0.384 53.0, 274.0 0.77
C57BL/6J m 176.0 70.3   16 17.6 0.399 55.0, 300.0 0.62
CAST/EiJ f 163.0 108.0   19 24.9 0.664 24.0, 300.0 0.28
CAST/EiJ m 173.0 113.0   17 27.3 0.652 0.55
NOD/ShiLtJ f 163.0 99.5   18 23.5 0.609 25.0, 300.0 0.28
NOD/ShiLtJ m 175.0 122.0   16 30.6 0.7 14.0, 300.0 0.6
NZO/HlLtJ f 163.0 54.8   17 13.3 0.337 22.0, 239.0 0.28
NZO/HlLtJ m 136.0 72.5   17 17.6 0.534 16.0, 300.0 -0.41
PWK/PhJ f 192.0 114.0   20 25.4 0.591 15.0, 300.0 1.07
PWK/PhJ m 189.0 109.0   22 23.2 0.576 17.0, 300.0 0.96


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 119.0625 21.442 161.3124 76.8126
129S1/SvImJ m 136.6875 21.442 178.9374 94.4376
A/J f 86.6875 21.442 128.9374 44.4376
A/J m 77.4375 21.442 119.6874 35.1876
C57BL/6J f 181.3125 21.442 223.5624 139.0626
C57BL/6J m 176.0625 21.442 218.3124 133.8126
CAST/EiJ f 163.1053 19.6766 201.8764 124.3341
CAST/EiJ m 172.7647 20.8018 213.7531 131.7763
NOD/ShiLtJ f 163.3889 20.2157 203.2225 123.5553
NOD/ShiLtJ m 174.75 21.442 216.9999 132.5001
NZO/HlLtJ f 162.5882 20.8018 203.5766 121.5998
NZO/HlLtJ m 135.7059 20.8018 176.6943 94.7175
PWK/PhJ f 192.25 19.1783 230.0394 154.4606
PWK/PhJ m 188.7273 18.2858 224.7581 152.6964


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 127.875 15.1618 157.7502 97.9998
A/J both 82.0625 15.1618 111.9377 52.1873
C57BL/6J both 178.6875 15.1618 208.5627 148.8123
CAST/EiJ both 167.935 14.3168 196.1451 139.7248
NOD/ShiLtJ both 169.0694 14.7346 198.1029 140.036
NZO/HlLtJ both 149.1471 14.7091 178.1302 120.1639
PWK/PhJ both 190.4886 13.2493 216.5954 164.3818




  GWAS USING LINEAR MIXED MODELS