Project measure / variable:   GMC02   all_paws_mean

ID, description, units MPD:55124   all_paws_mean   forelimb and hindlimb grip strength, mean   [g]  
Data set, strains GMC02   inbred w/CC8   8 strains     sex: both     age: 8-10wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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GMC02 - forelimb and hindlimb grip strength, mean



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means187   g 207   g
Median of the strain means190   g 222   g
SD of the strain means± 31.3 ± 38.1
Coefficient of variation (CV)0.167 0.184
Min–max range of strain means149   –   232   g 159   –   251   g
Mean sample size per strain17.4   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 24815.0517 24815.0517 50.0928 < 0.0001
strain 7 280631.8548 40090.265 80.928 < 0.0001
sex:strain 7 10909.5748 1558.5107 3.1461 0.0033
Residuals 258 127808.5675 495.382


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 177.0 13.1   16 3.27 0.0738 152.0, 197.0 -0.33
129S1/SvImJ m 224.0 18.8   16 4.71 0.0842 188.0, 261.0 0.45
A/J f 209.0 33.7   16 8.42 0.161 152.0, 274.0 0.69
A/J m 225.0 21.1   16 5.26 0.0934 183.0, 257.0 0.48
C57BL/6J f 215.0 24.7   16 6.16 0.114 174.0, 263.0 0.89
C57BL/6J m 247.0 36.0   16 9.0 0.146 197.0, 312.0 1.05
CAST/EiJ f 158.0 15.0   19 3.45 0.0954 141.0, 185.0 -0.93
CAST/EiJ m 159.0 19.0   17 4.6 0.119 120.0, 194.0 -1.26
NOD/ShiLtJ f 232.0 31.6   18 7.45 0.136 179.0, 274.0 1.43
NOD/ShiLtJ m 251.0 21.7   16 5.42 0.0864 190.0, 280.0 1.16
NZO/HlLtJ f 202.0 16.3   17 3.96 0.0809 180.0, 238.0 0.47
NZO/HlLtJ m 219.0 19.1   17 4.62 0.0872 174.0, 244.0 0.32
PWK/PhJ f 156.0 18.5   19 4.24 0.118 124.0, 189.0 -1.0
PWK/PhJ m 170.0 17.2   21 3.75 0.101 148.0, 205.0 -0.97
WSB/EiJ f 149.0 19.0   18 4.48 0.127 113.0, 178.0 -1.22
WSB/EiJ m 160.0 19.3   16 4.81 0.12 107.0, 184.0 -1.23


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 177.3331 5.5643 188.2903 166.3759
129S1/SvImJ m 223.6469 5.5643 234.6041 212.6897
A/J f 209.1456 5.5643 220.1028 198.1884
A/J m 225.2913 5.5643 236.2485 214.334
C57BL/6J f 215.3331 5.5643 226.2903 204.3759
C57BL/6J m 246.6038 5.5643 257.561 235.6465
CAST/EiJ f 157.6668 5.1061 167.7219 147.6118
CAST/EiJ m 158.9612 5.3982 169.5912 148.3311
NOD/ShiLtJ f 231.5378 5.2461 241.8683 221.2072
NOD/ShiLtJ m 251.125 5.5643 262.0822 240.1678
NZO/HlLtJ f 201.7059 5.3982 212.3359 191.0758
NZO/HlLtJ m 218.5494 5.3982 229.1795 207.9193
PWK/PhJ f 156.2458 5.1061 166.3008 146.1908
PWK/PhJ m 170.3814 4.8569 179.9457 160.8172
WSB/EiJ f 149.445 5.2461 159.7756 139.1144
WSB/EiJ m 160.1669 5.5643 171.1241 149.2097


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 200.49 3.9346 208.2379 192.7421
A/J both 217.2184 3.9346 224.9664 209.4705
C57BL/6J both 230.9684 3.9346 238.7164 223.2205
CAST/EiJ both 158.314 3.7153 165.6301 150.9979
NOD/ShiLtJ both 241.3314 3.8237 248.861 233.8018
NZO/HlLtJ both 210.1276 3.8171 217.6442 202.6111
PWK/PhJ both 163.3136 3.5236 170.2522 156.375
WSB/EiJ both 154.8059 3.8237 162.3356 147.2763




  GWAS USING LINEAR MIXED MODELS