Project measure / variable:   GMC02   all_paws2

ID, description, units MPD:55122   all_paws2   forelimb and hindlimb grip strength   [g]  trial2  
Data set, strains GMC02   inbred w/CC8   8 strains     sex: both     age: 8-10wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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GMC02 - forelimb and hindlimb grip strength trial2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means187   g 207   g
Median of the strain means190   g 222   g
SD of the strain means± 30.8 ± 38.1
Coefficient of variation (CV)0.165 0.184
Min–max range of strain means148   –   230   g 160   –   252   g
Mean sample size per strain17.4   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 25707.664 25707.664 46.0937 < 0.0001
strain 7 278557.8156 39793.9737 71.3503 < 0.0001
sex:strain 7 11074.5021 1582.0717 2.8366 0.0073
Residuals 258 143893.4636 557.7266


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 179.0 15.1   16 3.77 0.0844 150.0, 203.0 -0.27
129S1/SvImJ m 226.0 29.3   16 7.32 0.129 189.0, 299.0 0.5
A/J f 210.0 35.1   16 8.78 0.168 151.0, 279.0 0.74
A/J m 227.0 21.8   16 5.46 0.0963 183.0, 258.0 0.53
C57BL/6J f 214.0 26.7   16 6.67 0.125 173.0, 273.0 0.87
C57BL/6J m 244.0 38.3   16 9.58 0.157 195.0, 322.0 0.97
CAST/EiJ f 157.0 16.1   19 3.7 0.103 138.0, 187.0 -0.98
CAST/EiJ m 160.0 21.3   17 5.18 0.133 129.0, 203.0 -1.24
NOD/ShiLtJ f 230.0 30.4   18 7.17 0.132 179.0, 268.0 1.39
NOD/ShiLtJ m 252.0 16.9   16 4.24 0.0672 217.0, 272.0 1.18
NZO/HlLtJ f 202.0 17.4   17 4.23 0.0865 175.0, 239.0 0.48
NZO/HlLtJ m 218.0 17.7   17 4.29 0.0814 184.0, 243.0 0.29
PWK/PhJ f 158.0 19.9   19 4.58 0.126 117.0, 192.0 -0.95
PWK/PhJ m 169.0 17.5   21 3.82 0.104 141.0, 201.0 -1.0
WSB/EiJ f 148.0 21.6   18 5.08 0.146 108.0, 188.0 -1.27
WSB/EiJ m 160.0 20.3   16 5.07 0.127 98.0, 188.0 -1.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 178.5625 5.9041 190.1888 166.9362
129S1/SvImJ m 226.5 5.9041 238.1263 214.8737
A/J f 209.5 5.9041 221.1263 197.8737
A/J m 226.75 5.9041 238.3763 215.1237
C57BL/6J f 214.0 5.9041 225.6263 202.3737
C57BL/6J m 243.6875 5.9041 255.3138 232.0612
CAST/EiJ f 156.7368 5.4179 167.4058 146.0678
CAST/EiJ m 160.1765 5.7278 171.4556 148.8973
NOD/ShiLtJ f 229.8333 5.5664 240.7947 218.872
NOD/ShiLtJ m 252.25 5.9041 263.8763 240.6237
NZO/HlLtJ f 201.5294 5.7278 212.8086 190.2503
NZO/HlLtJ m 217.5294 5.7278 228.8086 206.2503
PWK/PhJ f 158.0526 5.4179 168.7216 147.3836
PWK/PhJ m 168.5238 5.1535 178.6721 158.3756
WSB/EiJ f 147.8889 5.5664 158.8503 136.9275
WSB/EiJ m 160.25 5.9041 171.8763 148.6237


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 202.5313 4.1748 210.7523 194.3102
A/J both 218.125 4.1748 226.346 209.904
C57BL/6J both 228.8438 4.1748 237.0648 220.6227
CAST/EiJ both 158.4567 3.9421 166.2195 150.6938
NOD/ShiLtJ both 241.0417 4.0572 249.0311 233.0523
NZO/HlLtJ both 209.5294 4.0502 217.505 201.5538
PWK/PhJ both 163.2882 3.7387 170.6505 155.9259
WSB/EiJ both 154.0694 4.0572 162.0588 146.08




  GWAS USING LINEAR MIXED MODELS