Project measure / variable:   GMC02   front_paws_adj

ID, description, units MPD:55115   front_paws_adj   forelimb grip strength (mean) normalized to body weight   [ratio]  
Data set, strains GMC02   inbred w/CC8   8 strains     sex: both     age: 8-10wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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GMC02 - forelimb grip strength (mean) normalized to body weight



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means5.40   ratio 4.91   ratio
Median of the strain means5.80   ratio 5.25   ratio
SD of the strain means± 1.22 ± 1.06
Coefficient of variation (CV)0.225 0.216
Min–max range of strain means2.58   –   6.37   ratio 2.42   –   5.79   ratio
Mean sample size per strain17.5   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 18.2353 18.2353 30.701 < 0.0001
strain 7 308.4123 44.0589 74.1776 < 0.0001
sex:strain 7 4.3987 0.6284 1.058 0.3912
Residuals 259 153.8369 0.594


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.09 0.5   16 0.125 0.0984 4.14, 6.16 -0.25
129S1/SvImJ m 4.81 0.287   16 0.0718 0.0597 4.46, 5.43 -0.09
A/J f 5.97 0.924   16 0.231 0.155 4.34, 7.52 0.47
A/J m 5.47 1.05   16 0.263 0.193 4.16, 7.43 0.53
C57BL/6J f 5.64 0.674   16 0.168 0.12 4.67, 6.88 0.2
C57BL/6J m 4.84 0.718   16 0.18 0.148 3.78, 6.04 -0.07
CAST/EiJ f 6.37 0.748   19 0.172 0.117 5.5, 8.29 0.8
CAST/EiJ m 5.45 0.484   17 0.117 0.0887 4.2, 6.12 0.51
NOD/ShiLtJ f 5.36 0.633   18 0.149 0.118 4.37, 6.84 -0.03
NOD/ShiLtJ m 5.11 0.522   16 0.13 0.102 4.36, 6.21 0.19
NZO/HlLtJ f 2.58 0.344   17 0.0834 0.134 2.01, 3.57 -2.32
NZO/HlLtJ m 2.42 0.237   17 0.0576 0.098 1.92, 2.72 -2.35
PWK/PhJ f 5.99 1.11   20 0.249 0.186 4.05, 7.93 0.48
PWK/PhJ m 5.39 1.15   21 0.251 0.214 3.72, 7.8 0.45
WSB/EiJ f 6.2 0.854   18 0.201 0.138 5.06, 7.66 0.66
WSB/EiJ m 5.79 0.995   16 0.249 0.172 3.91, 7.02 0.83


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.0856 0.1927 5.465 4.7062
129S1/SvImJ m 4.8125 0.1927 5.1919 4.4331
A/J f 5.9719 0.1927 6.3513 5.5925
A/J m 5.4662 0.1927 5.8457 5.0868
C57BL/6J f 5.6387 0.1927 6.0182 5.2593
C57BL/6J m 4.8369 0.1927 5.2163 4.4575
CAST/EiJ f 6.3695 0.1768 6.7176 6.0213
CAST/EiJ m 5.4541 0.1869 5.8222 5.086
NOD/ShiLtJ f 5.3639 0.1817 5.7216 5.0062
NOD/ShiLtJ m 5.1112 0.1927 5.4907 4.7318
NZO/HlLtJ f 2.5759 0.1869 2.944 2.2078
NZO/HlLtJ m 2.4229 0.1869 2.791 2.0549
PWK/PhJ f 5.9895 0.1723 6.3288 5.6502
PWK/PhJ m 5.3867 0.1682 5.7178 5.0555
WSB/EiJ f 6.2039 0.1817 6.5616 5.8462
WSB/EiJ m 5.7887 0.1927 6.1682 5.4093


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.9491 0.1362 5.2173 4.6808
A/J both 5.7191 0.1362 5.9873 5.4508
C57BL/6J both 5.2378 0.1362 5.5061 4.9695
CAST/EiJ both 5.9118 0.1286 6.1651 5.6585
NOD/ShiLtJ both 5.2376 0.1324 5.4983 4.9768
NZO/HlLtJ both 2.4994 0.1322 2.7597 2.2391
PWK/PhJ both 5.6881 0.1204 5.9252 5.451
WSB/EiJ both 5.9963 0.1324 6.257 5.7356




  GWAS USING LINEAR MIXED MODELS