Project measure / variable:   GMC02   front_paws_mean

ID, description, units MPD:55114   front_paws_mean   forelimb grip strength, mean   [g]  
Data set, strains GMC02   inbred w/CC8   8 strains     sex: both     age: 8-10wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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GMC02 - forelimb grip strength, mean



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means101   g 113   g
Median of the strain means104   g 116   g
SD of the strain means± 15.2 ± 20.8
Coefficient of variation (CV)0.151 0.185
Min–max range of strain means81.5   –   120   g 86.1   –   143   g
Mean sample size per strain17.5   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9825.4147 9825.4147 49.9331 < 0.0001
strain 7 78199.2603 11171.3229 56.773 < 0.0001
sex:strain 7 2753.9969 393.4281 1.9994 0.0556
Residuals 259 50963.869 196.7717


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 106.0 7.53   16 1.88 0.0713 83.7, 115.0 0.35
129S1/SvImJ m 123.0 10.0   16 2.51 0.0815 107.0, 140.0 0.49
A/J f 118.0 18.9   16 4.73 0.16 87.3, 153.0 1.13
A/J m 128.0 23.5   16 5.88 0.184 100.0, 172.0 0.73
C57BL/6J f 109.0 10.6   16 2.66 0.0981 86.3, 126.0 0.54
C57BL/6J m 128.0 19.3   16 4.83 0.151 96.3, 156.0 0.73
CAST/EiJ f 81.5 10.2   19 2.34 0.125 72.0, 106.0 -1.26
CAST/EiJ m 86.1 9.02   17 2.19 0.105 67.7, 105.0 -1.28
NOD/ShiLtJ f 120.0 12.6   18 2.96 0.104 98.7, 145.0 1.27
NOD/ShiLtJ m 143.0 15.4   16 3.84 0.107 115.0, 163.0 1.45
NZO/HlLtJ f 101.0 8.75   17 2.12 0.0867 81.0, 118.0 0.02
NZO/HlLtJ m 110.0 8.52   17 2.07 0.0775 95.7, 125.0 -0.14
PWK/PhJ f 84.2 14.9   20 3.34 0.177 58.7, 119.0 -1.09
PWK/PhJ m 92.2 17.9   21 3.91 0.194 68.0, 137.0 -0.99
WSB/EiJ f 86.2 11.2   18 2.63 0.13 66.7, 103.0 -0.96
WSB/EiJ m 92.5 14.3   16 3.58 0.155 65.0, 116.0 -0.98


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 105.73 3.5069 112.6356 98.8244
129S1/SvImJ m 123.1669 3.5069 130.0725 116.2612
A/J f 118.2494 3.5069 125.155 111.3437
A/J m 127.7512 3.5069 134.6569 120.8456
C57BL/6J f 108.5412 3.5069 115.4469 101.6356
C57BL/6J m 127.7087 3.5069 134.6144 120.8031
CAST/EiJ f 81.4563 3.2181 87.7934 75.1193
CAST/EiJ m 86.0594 3.4022 92.7589 79.36
NOD/ShiLtJ f 120.2789 3.3063 126.7896 113.7682
NOD/ShiLtJ m 143.3956 3.5069 150.3013 136.49
NZO/HlLtJ f 101.0 3.4022 107.6994 94.3006
NZO/HlLtJ m 109.9029 3.4022 116.6024 103.2035
PWK/PhJ f 84.1835 3.1367 90.3601 78.0069
PWK/PhJ m 92.2062 3.0611 98.2339 86.1785
WSB/EiJ f 86.1661 3.3063 92.6768 79.6554
WSB/EiJ m 92.4581 3.5069 99.3638 85.5525


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 114.4484 2.4797 119.3315 109.5654
A/J both 123.0003 2.4797 127.8833 118.1173
C57BL/6J both 118.125 2.4797 123.008 113.242
CAST/EiJ both 83.7579 2.3415 88.3687 79.147
NOD/ShiLtJ both 131.8373 2.4099 136.5827 127.0918
NZO/HlLtJ both 105.4515 2.4057 110.1887 100.7142
PWK/PhJ both 88.1948 2.1914 92.51 83.8796
WSB/EiJ both 89.3121 2.4099 94.0576 84.5667




  GWAS USING LINEAR MIXED MODELS