Project measure / variable:   GMC02   front_paws3

ID, description, units MPD:55113   front_paws3   forelimb grip strength   [g]  trial3  
Data set, strains GMC02   inbred w/CC8   8 strains     sex: both     age: 8-10wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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GMC02 - forelimb grip strength trial3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means102   g 115   g
Median of the strain means104   g 118   g
SD of the strain means± 15.3 ± 21.5
Coefficient of variation (CV)0.151 0.188
Min–max range of strain means79.7   –   120   g 86.6   –   147   g
Mean sample size per strain17.5   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 11139.1204 11139.1204 44.0899 < 0.0001
strain 7 80877.6657 11553.9522 45.7319 < 0.0001
sex:strain 7 3395.5802 485.0829 1.92 0.0667
Residuals 259 65435.1756 252.6455


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 106.0 9.42   16 2.35 0.0889 80.0, 116.0 0.28
129S1/SvImJ m 126.0 13.1   16 3.28 0.104 107.0, 152.0 0.53
A/J f 119.0 20.6   16 5.14 0.173 88.0, 150.0 1.13
A/J m 131.0 24.0   16 5.99 0.182 99.0, 177.0 0.76
C57BL/6J f 112.0 13.2   16 3.29 0.118 92.0, 134.0 0.67
C57BL/6J m 128.0 21.1   16 5.29 0.165 94.0, 161.0 0.62
CAST/EiJ f 79.7 10.0   19 2.3 0.126 71.0, 101.0 -1.44
CAST/EiJ m 86.6 13.4   17 3.25 0.155 64.0, 115.0 -1.3
NOD/ShiLtJ f 120.0 13.1   18 3.09 0.109 94.0, 140.0 1.19
NOD/ShiLtJ m 147.0 15.9   16 3.97 0.108 120.0, 169.0 1.51
NZO/HlLtJ f 102.0 11.7   17 2.85 0.115 79.0, 128.0 0.02
NZO/HlLtJ m 109.0 10.0   17 2.43 0.092 95.0, 128.0 -0.26
PWK/PhJ f 86.6 19.0   20 4.24 0.219 55.0, 126.0 -0.99
PWK/PhJ m 95.0 20.0   21 4.36 0.21 69.0, 133.0 -0.91
WSB/EiJ f 88.5 14.0   18 3.31 0.159 62.0, 113.0 -0.86
WSB/EiJ m 94.2 16.1   16 4.02 0.171 61.0, 120.0 -0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 105.875 3.9737 113.6999 98.0501
129S1/SvImJ m 126.375 3.9737 134.1999 118.5501
A/J f 118.875 3.9737 126.6999 111.0501
A/J m 131.3125 3.9737 139.1374 123.4876
C57BL/6J f 111.875 3.9737 119.6999 104.0501
C57BL/6J m 128.125 3.9737 135.9499 120.3001
CAST/EiJ f 79.7368 3.6465 86.9174 72.5562
CAST/EiJ m 86.6471 3.8551 94.2383 79.0558
NOD/ShiLtJ f 120.3333 3.7464 127.7107 112.956
NOD/ShiLtJ m 146.6875 3.9737 154.5124 138.8626
NZO/HlLtJ f 102.2941 3.8551 109.8854 94.7029
NZO/HlLtJ m 108.8824 3.8551 116.4736 101.2911
PWK/PhJ f 86.6 3.5542 93.5988 79.6012
PWK/PhJ m 94.9524 3.4685 101.7825 88.1223
WSB/EiJ f 88.5 3.7464 95.8774 81.1226
WSB/EiJ m 94.1875 3.9737 102.0124 86.3626


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 116.125 2.8098 121.658 110.592
A/J both 125.0937 2.8098 130.6268 119.5607
C57BL/6J both 120.0 2.8098 125.533 114.467
CAST/EiJ both 83.192 2.6532 88.4166 77.9673
NOD/ShiLtJ both 133.5104 2.7307 138.8876 128.1333
NZO/HlLtJ both 105.5882 2.7259 110.9561 100.2204
PWK/PhJ both 90.7762 2.4831 95.6658 85.8866
WSB/EiJ both 91.3437 2.7307 96.7209 85.9666




  GWAS USING LINEAR MIXED MODELS