Project measure / variable:   GMC02   front_paws2

ID, description, units MPD:55112   front_paws2   forelimb grip strength   [g]  trial2  
Data set, strains GMC02   inbred w/CC8   8 strains     sex: both     age: 8-10wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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GMC02 - forelimb grip strength trial2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means101   g 113   g
Median of the strain means103   g 118   g
SD of the strain means± 15.2 ± 20.7
Coefficient of variation (CV)0.151 0.183
Min–max range of strain means82.9   –   120   g 85.4   –   141   g
Mean sample size per strain17.5   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9693.9945 9693.9945 41.4774 < 0.0001
strain 7 76556.3406 10936.6201 46.7942 < 0.0001
sex:strain 7 2950.7417 421.5345 1.8036 0.0868
Residuals 259 60532.8651 233.7176


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 106.0 9.86   16 2.46 0.0927 83.0, 123.0 0.34
129S1/SvImJ m 125.0 13.4   16 3.35 0.107 103.0, 149.0 0.59
A/J f 119.0 19.2   16 4.81 0.162 89.0, 156.0 1.19
A/J m 127.0 24.1   16 6.03 0.19 96.0, 175.0 0.69
C57BL/6J f 109.0 11.3   16 2.84 0.104 83.0, 126.0 0.54
C57BL/6J m 129.0 20.6   16 5.14 0.16 86.0, 162.0 0.78
CAST/EiJ f 82.9 12.8   19 2.94 0.155 68.0, 119.0 -1.18
CAST/EiJ m 85.4 9.5   17 2.3 0.111 64.0, 97.0 -1.33
NOD/ShiLtJ f 120.0 13.6   18 3.2 0.113 95.0, 149.0 1.26
NOD/ShiLtJ m 141.0 15.1   16 3.77 0.107 116.0, 163.0 1.36
NZO/HlLtJ f 100.0 11.9   17 2.89 0.119 81.0, 123.0 -0.05
NZO/HlLtJ m 110.0 14.7   17 3.56 0.133 96.0, 139.0 -0.14
PWK/PhJ f 84.4 16.8   20 3.75 0.199 60.0, 125.0 -1.08
PWK/PhJ m 93.8 19.1   21 4.16 0.203 73.0, 146.0 -0.92
WSB/EiJ f 85.3 11.6   18 2.73 0.136 60.0, 111.0 -1.02
WSB/EiJ m 91.4 12.3   16 3.08 0.135 69.0, 119.0 -1.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 106.375 3.822 113.9011 98.8489
129S1/SvImJ m 125.375 3.822 132.9011 117.8489
A/J f 118.9375 3.822 126.4636 111.4114
A/J m 126.75 3.822 134.2761 119.2239
C57BL/6J f 109.4375 3.822 116.9636 101.9114
C57BL/6J m 128.5625 3.822 136.0886 121.0364
CAST/EiJ f 82.8947 3.5073 89.8011 75.9883
CAST/EiJ m 85.3529 3.7078 92.6543 78.0516
NOD/ShiLtJ f 119.6111 3.6034 126.7068 112.5155
NOD/ShiLtJ m 141.375 3.822 148.9011 133.8489
NZO/HlLtJ f 100.1176 3.7078 107.419 92.8163
NZO/HlLtJ m 110.4118 3.7078 117.7131 103.1104
PWK/PhJ f 84.4 3.4185 91.1315 77.6685
PWK/PhJ m 93.7619 3.3361 100.3312 87.1926
WSB/EiJ f 85.2778 3.6034 92.3734 78.1821
WSB/EiJ m 91.375 3.822 98.9011 83.8489


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 115.875 2.7025 121.1967 110.5533
A/J both 122.8437 2.7025 128.1655 117.522
C57BL/6J both 119.0 2.7025 124.3217 113.6783
CAST/EiJ both 84.1238 2.5519 89.149 79.0987
NOD/ShiLtJ both 130.4931 2.6264 135.6648 125.3213
NZO/HlLtJ both 105.2647 2.6218 110.4275 100.1019
PWK/PhJ both 89.081 2.3883 93.7838 84.3781
WSB/EiJ both 88.3264 2.6264 93.4982 83.1546




  GWAS USING LINEAR MIXED MODELS