Project measure / variable:   GMC02   front_paws1

ID, description, units MPD:55111   front_paws1   forelimb grip strength   [g]  trial1  
Data set, strains GMC02   inbred w/CC8   8 strains     sex: both     age: 8-10wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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GMC02 - forelimb grip strength trial1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means99.5   g 111   g
Median of the strain means102   g 114   g
SD of the strain means± 15.4 ± 20.5
Coefficient of variation (CV)0.155 0.185
Min–max range of strain means81.7   –   121   g 86.2   –   142   g
Mean sample size per strain17.5   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 8606.9004 8606.9004 33.6114 < 0.0001
strain 7 78133.3832 11161.9119 43.5891 < 0.0001
sex:strain 7 2685.9851 383.7122 1.4985 0.168
Residuals 259 66322.4076 256.0711


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 105.0 12.0   16 3.01 0.115 88.0, 130.0 0.35
129S1/SvImJ m 118.0 13.4   16 3.34 0.113 89.0, 145.0 0.35
A/J f 117.0 20.1   16 5.03 0.172 83.0, 152.0 1.13
A/J m 125.0 26.4   16 6.59 0.21 91.0, 177.0 0.69
C57BL/6J f 104.0 12.9   16 3.21 0.123 82.0, 122.0 0.29
C57BL/6J m 126.0 18.8   16 4.7 0.149 100.0, 155.0 0.74
CAST/EiJ f 81.9 12.8   19 2.93 0.156 63.0, 100.0 -1.14
CAST/EiJ m 86.2 9.78   17 2.37 0.113 67.0, 102.0 -1.2
NOD/ShiLtJ f 121.0 15.6   18 3.68 0.129 91.0, 147.0 1.39
NOD/ShiLtJ m 142.0 18.8   16 4.71 0.133 109.0, 169.0 1.52
NZO/HlLtJ f 101.0 12.3   17 2.99 0.122 81.0, 130.0 0.1
NZO/HlLtJ m 110.0 12.4   17 3.01 0.112 85.0, 134.0 -0.04
PWK/PhJ f 81.7 12.7   20 2.83 0.155 59.0, 116.0 -1.15
PWK/PhJ m 88.0 18.8   21 4.11 0.214 61.0, 136.0 -1.11
WSB/EiJ f 84.6 13.6   18 3.21 0.161 62.0, 109.0 -0.97
WSB/EiJ m 91.7 18.5   16 4.62 0.201 66.0, 127.0 -0.93


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 105.0 4.0006 112.8778 97.1222
129S1/SvImJ m 117.6875 4.0006 125.5653 109.8097
A/J f 117.0 4.0006 124.8778 109.1222
A/J m 125.25 4.0006 133.1278 117.3722
C57BL/6J f 104.5 4.0006 112.3778 96.6222
C57BL/6J m 126.5 4.0006 134.3778 118.6222
CAST/EiJ f 81.9474 3.6712 89.1765 74.7182
CAST/EiJ m 86.2353 3.8811 93.8778 78.5927
NOD/ShiLtJ f 120.9444 3.7718 128.3717 113.5172
NOD/ShiLtJ m 142.0625 4.0006 149.9403 134.1847
NZO/HlLtJ f 100.6471 3.8811 108.2896 93.0045
NZO/HlLtJ m 110.4118 3.8811 118.0543 102.7692
PWK/PhJ f 81.7 3.5782 88.7461 74.6539
PWK/PhJ m 88.0 3.492 94.8763 81.1237
WSB/EiJ f 84.5556 3.7718 91.9828 77.1283
WSB/EiJ m 91.6875 4.0006 99.5653 83.8097


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 111.3437 2.8288 116.9142 105.7733
A/J both 121.125 2.8288 126.6954 115.5546
C57BL/6J both 115.5 2.8288 121.0704 109.9296
CAST/EiJ both 84.0913 2.6712 89.3513 78.8314
NOD/ShiLtJ both 131.5035 2.7491 136.9169 126.09
NZO/HlLtJ both 105.5294 2.7444 110.9335 100.1253
PWK/PhJ both 84.85 2.4999 89.7727 79.9273
WSB/EiJ both 88.1215 2.7491 93.535 82.7081




  GWAS USING LINEAR MIXED MODELS