Project measure / variable:   Korstanje2   pct_MME_M20

ID, description, units MPD:51003   pct_MME_M20   percentage of glomeruli exhibiting mesangial matrix expansion   [%]  at age 20mo  
Data set, strains Korstanje2   inbred   27 strains     sex: m     age: 87wks
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  STRAIN COMPARISON PLOT
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Korstanje2 - percentage of glomeruli exhibiting mesangial matrix expansion at age 20mo



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested27 strains
Mean of the strain means15.2   %
Median of the strain means10.7   %
SD of the strain means± 10.9
Coefficient of variation (CV)0.717
Min–max range of strain means0.333   –   35.0   %
Mean sample size per strain5.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 26 16641.0027 640.0386 5.8777 < 0.0001
Residuals 120 13067.1333 108.8928


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 5.67 2.66   6 1.09 0.469 2.0, 8.0 -0.88
BALB/cByJ m 15.0 15.4   6 6.3 1.03 6.0, 46.0 -0.02
BTBR T+ Itpr3tf/J m 9.0 3.29   6 1.34 0.365 4.0, 14.0 -0.57
BUB/BnJ m 35.0 32.5   2   23.0 0.929 12.0, 58.0 1.81
C3H/HeJ m 4.33 2.34   6 0.955 0.54 2.0, 8.0 -1.0
C57BL/10J m 22.7 19.2   6 7.83 0.846 2.0, 54.0 0.68
C57BL/6J m 15.7 11.8   6 4.8 0.751 0.04
C57BLKS/J m 6.67 3.01   6 1.23 0.452 2.0, 10.0 -0.78
C57BR/cdJ m 34.0 24.8   6 10.1 0.729 12.0, 80.0 1.72
C57L/J m 9.0 5.76   6 2.35 0.64 4.0, 20.0 -0.57
CBA/J m 10.7 3.93   6 1.61 0.369 4.0, 14.0 -0.42
DBA/2J m 6.67 4.32   6 1.76 0.648 -0.78
FVB/NJ m 8.67 3.27   6 1.33 0.377 4.0, 12.0 -0.6
KK/HlJ m 34.7 19.0   6 7.77 0.549 14.0, 56.0 1.78
LP/J m 0.333 0.816   6 0.333 2.45 -1.36
MRL/MpJ m 26.5 9.29   4 4.65 0.351 14.0, 36.0 1.03
NOD.B10Sn-H2b/J m 35.0 7.46   6 3.04 0.213 24.0, 46.0 1.81
NON/ShiLtJ m 10.7 7.55   6 3.08 0.708 2.0, 22.0 -0.42
NZO/HlLtJ m 20.0 5.66   2   4.0 0.283 16.0, 24.0 0.44
NZW/LacJ m 28.0 13.0   6 5.32 0.465 12.0, 50.0 1.17
P/J m 17.2 4.38   5 1.96 0.255 12.0, 24.0 0.18
PL/J m 14.0 11.3   2   8.0 0.808 6.0, 22.0 -0.11
PWD/PhJ m 6.0 4.56   6 1.86 0.76 -0.85
RIIIS/J m 4.67 2.73   6 1.12 0.586 -0.97
SM/J m 22.3 11.3   6 4.6 0.505 2.0, 32.0 0.65
SWR/J m 6.0 4.73   6 1.93 0.789 -0.85
WSB/EiJ m 3.0 3.29   6 1.34 1.1 -1.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 5.6667 4.2601 14.1014 0.0
BALB/cByJ m 15.0 4.2601 23.4348 6.5652
BTBR T+ Itpr3tf/J m 9.0 4.2601 17.4348 0.5652
BUB/BnJ m 35.0 7.3788 49.6095 20.3905
C3H/HeJ m 4.3333 4.2601 12.7681 0.0
C57BL/10J m 22.6667 4.2601 31.1014 14.2319
C57BL/6J m 15.6667 4.2601 24.1014 7.2319
C57BLKS/J m 6.6667 4.2601 15.1014 0.0
C57BR/cdJ m 34.0 4.2601 42.4348 25.5652
C57L/J m 9.0 4.2601 17.4348 0.5652
CBA/J m 10.6667 4.2601 19.1014 2.2319
DBA/2J m 6.6667 4.2601 15.1014 0.0
FVB/NJ m 8.6667 4.2601 17.1014 0.2319
KK/HlJ m 34.6667 4.2601 43.1014 26.2319
LP/J m 0.3333 4.2601 8.7681 0.0
MRL/MpJ m 26.5 5.2176 36.8305 16.1695
NOD.B10Sn-H2b/J m 35.0 4.2601 43.4348 26.5652
NON/ShiLtJ m 10.6667 4.2601 19.1014 2.2319
NZO/HlLtJ m 20.0 7.3788 34.6095 5.3905
NZW/LacJ m 28.0 4.2601 36.4348 19.5652
P/J m 17.2 4.6667 26.4398 7.9602
PL/J m 14.0 7.3788 28.6095 0.0
PWD/PhJ m 6.0 4.2601 14.4348 0.0
RIIIS/J m 4.6667 4.2601 13.1014 0.0
SM/J m 22.3333 4.2601 30.7681 13.8986
SWR/J m 6.0 4.2601 14.4348 0.0
WSB/EiJ m 3.0 4.2601 11.4348 0.0




  GWAS USING LINEAR MIXED MODELS