Project measure / variable:   HMDPpheno10   aminoisobutyrate

ID, description, units MPD:50518   aminoisobutyrate   3-aminoisobutyrate (16h fast), relative abundance    
Data set, strains HMDPpheno10   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno10 - 3-aminoisobutyrate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means173599   None
Median of the strain means159889   None
SD of the strain means± 86575
Coefficient of variation (CV)0.499
Min–max range of strain means57900   –   720540   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 72178416908.1798 3437067471.8181 2.1349 0.0238
Residuals 34 54738677952.9939 1609961116.2645


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 125788.0 0.0   1   0.0 0.0 125788.0, 125788.0 -0.55
A/J m 111017.0 13257.0   2   9374.0 0.119 101642.0, 120391.0 -0.72
AKR/J m 115765.0 0.0   1   0.0 0.0 115765.0, 115765.0 -0.67
AXB10/PgnJ m 106538.0 0.0   1   0.0 0.0 106538.0, 106538.0 -0.77
AXB12/PgnJ m 154996.0 0.0   1   0.0 0.0 154996.0, 154996.0 -0.21
AXB13/PgnJ m 105223.0 0.0   1   0.0 0.0 105223.0, 105223.0 -0.79
AXB15/PgnJ m 110201.0 0.0   1   0.0 0.0 110201.0, 110201.0 -0.73
AXB19a/PgnJ m 126595.0 0.0   1   0.0 0.0 126595.0, 126595.0 -0.54
AXB19b/PgnJ m 176116.0 3379.0   2   2389.0 0.0192 173727.0, 178506.0 0.03
AXB19/PgnJ m 155251.0 0.0   1   0.0 0.0 155251.0, 155251.0 -0.21
AXB1/PgnJ m 600699.0 0.0   1   0.0 0.0 600699.0, 600699.0 4.93
AXB23/PgnJ m 141747.0 0.0   1   0.0 0.0 141747.0, 141747.0 -0.37
AXB24/PgnJ m 228139.0 141805.0   2   100271.0 0.622 127867.0, 328410.0 0.63
AXB2/PgnJ m 329400.0 0.0   1   0.0 0.0 329400.0, 329400.0 1.8
AXB4/PgnJ m 329892.0 0.0   1   0.0 0.0 329892.0, 329892.0 1.81
AXB5/PgnJ m 226831.0 0.0   1   0.0 0.0 226831.0, 226831.0 0.61
AXB6/PgnJ m 182137.0 0.0   1   0.0 0.0 182137.0, 182137.0 0.1
AXB8/PgnJ m 136360.0 0.0   1   0.0 0.0 136360.0, 136360.0 -0.43
BALB/cJ m 219927.0 53501.0   3 30889.0 0.243 170188.0, 276528.0 0.54
BTBR T+ Itpr3tf/J m 96076.0 0.0   1   0.0 0.0 96076.0, 96076.0 -0.9
BUB/BnJ m 296849.0 0.0   1   0.0 0.0 296849.0, 296849.0 1.42
BXA11/PgnJ m 143234.0 0.0   1   0.0 0.0 143234.0, 143234.0 -0.35
BXA12/PgnJ m 126975.0 0.0   1   0.0 0.0 126975.0, 126975.0 -0.54
BXA13/PgnJ m 177254.0 0.0   1   0.0 0.0 177254.0, 177254.0 0.04
BXA14/PgnJ m 192329.0 0.0   1   0.0 0.0 192329.0, 192329.0 0.22
BXA16/PgnJ m 157582.0 2831.0   2   2002.0 0.018 155580.0, 159583.0 -0.19
BXA1/PgnJ m 118209.0 0.0   1   0.0 0.0 118209.0, 118209.0 -0.64
BXA24/PgnJ m 155756.0 0.0   1   0.0 0.0 155756.0, 155756.0 -0.21
BXA25/PgnJ m 131854.0 0.0   1   0.0 0.0 131854.0, 131854.0 -0.48
BXA26/PgnJ m 172949.0 0.0   1   0.0 0.0 172949.0, 172949.0 -0.01
BXA2/PgnJ m 175602.0 0.0   1   0.0 0.0 175602.0, 175602.0 0.02
BXA4/PgnJ m 61777.0 0.0   1   0.0 0.0 61777.0, 61777.0 -1.29
BXA7/PgnJ m 166755.0 0.0   1   0.0 0.0 166755.0, 166755.0 -0.08
BXA8/PgnJ m 96657.0 0.0   1   0.0 0.0 96657.0, 96657.0 -0.89
BXD11/TyJ m 155800.0 0.0   1   0.0 0.0 155800.0, 155800.0 -0.21
BXD12/TyJ m 199414.0 0.0   1   0.0 0.0 199414.0, 199414.0 0.3
BXD13/TyJ m 134184.0 0.0   1   0.0 0.0 134184.0, 134184.0 -0.46
BXD14/TyJ m 100543.0 0.0   1   0.0 0.0 100543.0, 100543.0 -0.84
BXD15/TyJ m 168604.0 0.0   1   0.0 0.0 168604.0, 168604.0 -0.06
BXD18/TyJ m 158092.0 0.0   1   0.0 0.0 158092.0, 158092.0 -0.18
BXD19/TyJ m 139495.0 26396.0   2   18665.0 0.189 120830.0, 158159.0 -0.39
BXD1/TyJ m 175749.0 0.0   1   0.0 0.0 175749.0, 175749.0 0.02
BXD20/TyJ m 192020.0 0.0   1   0.0 0.0 192020.0, 192020.0 0.21
BXD21/TyJ m 170128.0 0.0   1   0.0 0.0 170128.0, 170128.0 -0.04
BXD22/TyJ m 174560.0 0.0   1   0.0 0.0 174560.0, 174560.0 0.01
BXD24/TyJ m 103815.0 0.0   1   0.0 0.0 103815.0, 103815.0 -0.81
BXD24/TyJ-Cep290rd16/J m 100266.0 0.0   1   0.0 0.0 100266.0, 100266.0 -0.85
BXD28/TyJ m 144713.0 22093.0   2   15622.0 0.153 129091.0, 160336.0 -0.33
BXD29-Tlr4lps-2J/J m 129064.0 0.0   1   0.0 0.0 129064.0, 129064.0 -0.51
BXD2/TyJ m 261114.0 0.0   1   0.0 0.0 261114.0, 261114.0 1.01
BXD32/TyJ m 180445.0 0.0   1   0.0 0.0 180445.0, 180445.0 0.08
BXD33/TyJ m 276297.0 0.0   1   0.0 0.0 276297.0, 276297.0 1.19
BXD34/TyJ m 380226.0 0.0   1   0.0 0.0 380226.0, 380226.0 2.39
BXD36/TyJ m 158538.0 0.0   1   0.0 0.0 158538.0, 158538.0 -0.17
BXD38/TyJ m 162364.0 0.0   1   0.0 0.0 162364.0, 162364.0 -0.13
BXD39/TyJ m 84492.0 0.0   1   0.0 0.0 84492.0, 84492.0 -1.03
BXD40/TyJ m 187310.0 0.0   1   0.0 0.0 187310.0, 187310.0 0.16
BXD42/TyJ m 117214.0 0.0   1   0.0 0.0 117214.0, 117214.0 -0.65
BXD5/TyJ m 112939.0 0.0   1   0.0 0.0 112939.0, 112939.0 -0.7
BXD6/TyJ m 162984.0 0.0   1   0.0 0.0 162984.0, 162984.0 -0.12
BXD8/TyJ m 219866.0 0.0   1   0.0 0.0 219866.0, 219866.0 0.53
BXD9/TyJ m 112128.0 0.0   1   0.0 0.0 112128.0, 112128.0 -0.71
BXH10/TyJ m 165104.0 0.0   1   0.0 0.0 165104.0, 165104.0 -0.1
BXH19/TyJ m 57900.0 0.0   1   0.0 0.0 57900.0, 57900.0 -1.34
BXH20/KccJ m 130830.0 0.0   1   0.0 0.0 130830.0, 130830.0 -0.49
BXH22/KccJ m 160161.0 0.0   1   0.0 0.0 160161.0, 160161.0 -0.16
BXH2/TyJ m 162811.0 0.0   1   0.0 0.0 162811.0, 162811.0 -0.12
BXH4/TyJ m 141353.0 34811.0   2   24615.0 0.246 116738.0, 165968.0 -0.37
BXH6/TyJ m 181211.0 0.0   1   0.0 0.0 181211.0, 181211.0 0.09
BXH7/TyJ m 199895.0 0.0   1   0.0 0.0 199895.0, 199895.0 0.3
BXH8/TyJ m 135139.0 0.0   1   0.0 0.0 135139.0, 135139.0 -0.44
BXH9/TyJ m 124697.0 0.0   1   0.0 0.0 124697.0, 124697.0 -0.56
C3H/HeJ m 135068.0 9219.0   2   6519.0 0.0683 128549.0, 141586.0 -0.45
C57BL/6J m 201601.0 23366.0   5 10450.0 0.116 166540.0, 228375.0 0.32
C57L/J m 230791.0 0.0   1   0.0 0.0 230791.0, 230791.0 0.66
C58/J m 720540.0 0.0   1   0.0 0.0 720540.0, 720540.0 6.32
CAST/EiJ m 126540.0 0.0   1   0.0 0.0 126540.0, 126540.0 -0.54
CBA/J m 160567.0 0.0   1   0.0 0.0 160567.0, 160567.0 -0.15
CE/J m 227640.0 0.0   1   0.0 0.0 227640.0, 227640.0 0.62
CXB11/HiAJ m 192980.0 79376.0   2   56127.0 0.411 136852.0, 249107.0 0.22
CXB12/HiAJ m 189877.0 12343.0   2   8727.0 0.065 181149.0, 198604.0 0.19
CXB13/HiAJ m 216875.0 25532.0   3 14741.0 0.118 188445.0, 237848.0 0.5
CXB1/ByJ m 196904.0 61895.0   3 35735.0 0.314 128284.0, 248518.0 0.27
CXB2/ByJ m 209364.0 43761.0   3 25265.0 0.209 165757.0, 253276.0 0.41
CXB3/ByJ m 201040.0 11377.0   2   8045.0 0.0566 192996.0, 209085.0 0.32
CXB4/ByJ m 130438.0 9862.0   2   6973.0 0.0756 123465.0, 137412.0 -0.5
CXB6/ByJ m 219611.0 14001.0   3 8084.0 0.0638 209065.0, 235496.0 0.53
CXB7/ByJ m 174136.0 24045.0   2   17002.0 0.138 157134.0, 191138.0 0.01
CXB8/HiAJ m 163524.0 27707.0   3 15997.0 0.169 140524.0, 194284.0 -0.12
CXB9/HiAJ m 148932.0 14771.0   3 8528.0 0.0992 136274.0, 165161.0 -0.28
DBA/2J m 117326.0 23291.0   4 11645.0 0.199 101868.0, 151714.0 -0.65
FVB/NJ m 219999.0 0.0   1   0.0 0.0 219999.0, 219999.0 0.54
I/LnJ m 230710.0 0.0   1   0.0 0.0 230710.0, 230710.0 0.66
KK/HlJ m 159617.0 0.0   1   0.0 0.0 159617.0, 159617.0 -0.16
LG/J m 128569.0 0.0   1   0.0 0.0 128569.0, 128569.0 -0.52
LP/J m 127740.0 0.0   1   0.0 0.0 127740.0, 127740.0 -0.53
MA/MyJ m 167230.0 0.0   1   0.0 0.0 167230.0, 167230.0 -0.07
NOD/ShiLtJ m 180252.0 0.0   1   0.0 0.0 180252.0, 180252.0 0.08
NON/ShiLtJ m 109833.0 0.0   1   0.0 0.0 109833.0, 109833.0 -0.74
NZW/LacJ m 109394.0 0.0   1   0.0 0.0 109394.0, 109394.0 -0.74
PL/J m 157919.0 0.0   1   0.0 0.0 157919.0, 157919.0 -0.18
RIIIS/J m 127025.0 0.0   1   0.0 0.0 127025.0, 127025.0 -0.54
SEA/GnJ m 167240.0 0.0   1   0.0 0.0 167240.0, 167240.0 -0.07
SJL/J m 155340.0 0.0   1   0.0 0.0 155340.0, 155340.0 -0.21
SM/J m 183654.0 0.0   1   0.0 0.0 183654.0, 183654.0 0.12
SWR/J m 139319.0 0.0   1   0.0 0.0 139319.0, 139319.0 -0.4


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 111016.65 28372.1793 168675.8556 53357.4444
AXB19b/PgnJ m 176116.3 28372.1793 233775.5056 118457.0944
AXB24/PgnJ m 228138.55 28372.1793 285797.7556 170479.3444
BALB/cJ m 219926.5667 23165.7874 267005.1109 172848.0224
BXA16/PgnJ m 157581.55 28372.1793 215240.7556 99922.3444
BXD19/TyJ m 139494.55 28372.1793 197153.7556 81835.3444
BXD28/TyJ m 144713.35 28372.1793 202372.5556 87054.1444
BXH4/TyJ m 141353.25 28372.1793 199012.4556 83694.0444
C3H/HeJ m 135067.85 28372.1793 192727.0556 77408.6444
C57BL/6J m 201601.08 17944.1418 238067.9636 165134.1964
CXB11/HiAJ m 192979.85 28372.1793 250639.0556 135320.6444
CXB12/HiAJ m 189876.7 28372.1793 247535.9056 132217.4944
CXB13/HiAJ m 216875.1333 23165.7874 263953.6776 169796.5891
CXB1/ByJ m 196903.5333 23165.7874 243982.0776 149824.9891
CXB2/ByJ m 209364.4 23165.7874 256442.9442 162285.8558
CXB3/ByJ m 201040.2 28372.1793 258699.4056 143380.9944
CXB4/ByJ m 130438.4 28372.1793 188097.6056 72779.1944
CXB6/ByJ m 219610.9333 23165.7874 266689.4776 172532.3891
CXB7/ByJ m 174136.15 28372.1793 231795.3556 116476.9444
CXB8/HiAJ m 163524.3333 23165.7874 210602.8776 116445.7891
CXB9/HiAJ m 148931.5 23165.7874 196010.0442 101852.9558
DBA/2J m 117325.925 20062.1604 158097.1403 76554.7097




  GWAS USING LINEAR MIXED MODELS