Phenotype measure:   HMDPpheno8   alpha_muricholate

ID, description, units MPD:50301   alpha_muricholate   alpha-muricholate (16h fast), relative abundance  
Data set, strains HMDPpheno8   HMDP   104 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno8 - alpha-muricholate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested104 strains
Mean of the strain means1260921   None
Median of the strain means1125018   None
SD of the strain means± 744989
Coefficient of variation (CV)0.591
Min–max range of strain means102158   –   4038471   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 9588473518253.82 456593977059.706 0.9172 0.5739
Residuals 34 16925302223307.2 497803006567.859


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 341819.0 0.0   1   0.0 0.0 341819.0, 341819.0 -1.23
A/J m 1152911.0 459655.0   2   325025.0 0.399 827885.0, 1477936.0 -0.14
AKR/J m 2023136.0 0.0   1   0.0 0.0 2023136.0, 2023136.0 1.02
AXB10/PgnJ m 1795806.0 0.0   1   0.0 0.0 1795806.0, 1795806.0 0.72
AXB12/PgnJ m 1034328.0 0.0   1   0.0 0.0 1034328.0, 1034328.0 -0.3
AXB13/PgnJ m 1373805.0 0.0   1   0.0 0.0 1373805.0, 1373805.0 0.15
AXB15/PgnJ m 656256.0 0.0   1   0.0 0.0 656256.0, 656256.0 -0.81
AXB19a/PgnJ m 1128965.0 0.0   1   0.0 0.0 1128965.0, 1128965.0 -0.18
AXB19b/PgnJ m 2071221.0 1205687.0   2   852549.0 0.582 1218672.0, 2923770.0 1.09
AXB19/PgnJ m 1206335.0 0.0   1   0.0 0.0 1206335.0, 1206335.0 -0.07
AXB1/PgnJ m 548266.0 0.0   1   0.0 0.0 548266.0, 548266.0 -0.96
AXB23/PgnJ m 509475.0 0.0   1   0.0 0.0 509475.0, 509475.0 -1.01
AXB24/PgnJ m 669080.0 45138.0   2   31917.0 0.0675 637162.0, 700997.0 -0.79
AXB2/PgnJ m 1205019.0 0.0   1   0.0 0.0 1205019.0, 1205019.0 -0.08
AXB4/PgnJ m 510883.0 0.0   1   0.0 0.0 510883.0, 510883.0 -1.01
AXB5/PgnJ m 1451702.0 0.0   1   0.0 0.0 1451702.0, 1451702.0 0.26
AXB6/PgnJ m 1080752.0 0.0   1   0.0 0.0 1080752.0, 1080752.0 -0.24
AXB8/PgnJ m 1999917.0 0.0   1   0.0 0.0 1999917.0, 1999917.0 0.99
BALB/cJ m 1766153.0 1275349.0   3 736323.0 0.722 775803.0, 3205214.0 0.68
BTBR T+ Itpr3tf/J m 483566.0 0.0   1   0.0 0.0 483566.0, 483566.0 -1.04
BUB/BnJ m 1080752.0 0.0   1   0.0 0.0 1080752.0, 1080752.0 -0.24
BXA11/PgnJ m 1674260.0 0.0   1   0.0 0.0 1674260.0, 1674260.0 0.55
BXA12/PgnJ m 813212.0 0.0   1   0.0 0.0 813212.0, 813212.0 -0.6
BXA13/PgnJ m 1428084.0 0.0   1   0.0 0.0 1428084.0, 1428084.0 0.22
BXA14/PgnJ m 2333820.0 0.0   1   0.0 0.0 2333820.0, 2333820.0 1.44
BXA16/PgnJ m 585453.0 379247.0   2   268168.0 0.648 317286.0, 853621.0 -0.91
BXA1/PgnJ m 468627.0 0.0   1   0.0 0.0 468627.0, 468627.0 -1.06
BXA24/PgnJ m 1190730.0 0.0   1   0.0 0.0 1190730.0, 1190730.0 -0.09
BXA25/PgnJ m 1067343.0 0.0   1   0.0 0.0 1067343.0, 1067343.0 -0.26
BXA26/PgnJ m 970773.0 0.0   1   0.0 0.0 970773.0, 970773.0 -0.39
BXA2/PgnJ m 1249096.0 0.0   1   0.0 0.0 1249096.0, 1249096.0 -0.02
BXA4/PgnJ m 421031.0 0.0   1   0.0 0.0 421031.0, 421031.0 -1.13
BXA7/PgnJ m 1150570.0 0.0   1   0.0 0.0 1150570.0, 1150570.0 -0.15
BXA8/PgnJ m 1872644.0 0.0   1   0.0 0.0 1872644.0, 1872644.0 0.82
BXD11/TyJ m 2754409.0 0.0   1   0.0 0.0 2754409.0, 2754409.0 2.0
BXD12/TyJ m 624080.0 0.0   1   0.0 0.0 624080.0, 624080.0 -0.85
BXD13/TyJ m 1073933.0 0.0   1   0.0 0.0 1073933.0, 1073933.0 -0.25
BXD14/TyJ m 1196766.0 0.0   1   0.0 0.0 1196766.0, 1196766.0 -0.09
BXD15/TyJ m 1505983.0 0.0   1   0.0 0.0 1505983.0, 1505983.0 0.33
BXD18/TyJ m 102158.0 0.0   1   0.0 0.0 102158.0, 102158.0 -1.56
BXD19/TyJ m 1343102.0 667229.0   2   471802.0 0.497 871300.0, 1814904.0 0.11
BXD1/TyJ m 883178.0 0.0   1   0.0 0.0 883178.0, 883178.0 -0.51
BXD20/TyJ m 619546.0 0.0   1   0.0 0.0 619546.0, 619546.0 -0.86
BXD21/TyJ m 711596.0 0.0   1   0.0 0.0 711596.0, 711596.0 -0.74
BXD22/TyJ m 984544.0 0.0   1   0.0 0.0 984544.0, 984544.0 -0.37
BXD24/TyJ m 1810424.0 0.0   1   0.0 0.0 1810424.0, 1810424.0 0.74
BXD24/TyJ-Cep290rd16/J m 2326144.0 0.0   1   0.0 0.0 2326144.0, 2326144.0 1.43
BXD28/TyJ m 718004.0 14276.0   2   10095.0 0.0199 707909.0, 728099.0 -0.73
BXD29-Tlr4lps-2J/J m 529122.0 0.0   1   0.0 0.0 529122.0, 529122.0 -0.98
BXD2/TyJ m 734650.0 0.0   1   0.0 0.0 734650.0, 734650.0 -0.71
BXD32/TyJ m 1519770.0 0.0   1   0.0 0.0 1519770.0, 1519770.0 0.35
BXD33/TyJ m 1391363.0 0.0   1   0.0 0.0 1391363.0, 1391363.0 0.18
BXD34/TyJ m 2382282.0 0.0   1   0.0 0.0 2382282.0, 2382282.0 1.51
BXD36/TyJ m 1351158.0 0.0   1   0.0 0.0 1351158.0, 1351158.0 0.12
BXD38/TyJ m 3991370.0 0.0   1   0.0 0.0 3991370.0, 3991370.0 3.67
BXD39/TyJ m 772050.0 0.0   1   0.0 0.0 772050.0, 772050.0 -0.66
BXD40/TyJ m 1121072.0 0.0   1   0.0 0.0 1121072.0, 1121072.0 -0.19
BXD42/TyJ m 510681.0 0.0   1   0.0 0.0 510681.0, 510681.0 -1.01
BXD5/TyJ m 902207.0 0.0   1   0.0 0.0 902207.0, 902207.0 -0.48
BXD6/TyJ m 1022790.0 0.0   1   0.0 0.0 1022790.0, 1022790.0 -0.32
BXD8/TyJ m 782106.0 0.0   1   0.0 0.0 782106.0, 782106.0 -0.64
BXD9/TyJ m 976606.0 0.0   1   0.0 0.0 976606.0, 976606.0 -0.38
BXH10/TyJ m 316376.0 0.0   1   0.0 0.0 316376.0, 316376.0 -1.27
BXH19/TyJ m 1684328.0 0.0   1   0.0 0.0 1684328.0, 1684328.0 0.57
BXH20/KccJ m 911000.0 0.0   1   0.0 0.0 911000.0, 911000.0 -0.47
BXH22/KccJ m 286412.0 0.0   1   0.0 0.0 286412.0, 286412.0 -1.31
BXH2/TyJ m 736443.0 0.0   1   0.0 0.0 736443.0, 736443.0 -0.7
BXH4/TyJ m 644099.0 636482.0   2   450061.0 0.988 194039.0, 1094160.0 -0.83
BXH6/TyJ m 1765047.0 0.0   1   0.0 0.0 1765047.0, 1765047.0 0.68
BXH7/TyJ m 610728.0 0.0   1   0.0 0.0 610728.0, 610728.0 -0.87
BXH9/TyJ m 3247539.0 0.0   1   0.0 0.0 3247539.0, 3247539.0 2.67
C3H/HeJ m 1134562.0 836617.0   2   591577.0 0.737 542985.0, 1726139.0 -0.17
C57BL/6J m 1843428.0 931802.0   5 416714.0 0.505 1098791.0, 3364606.0 0.78
C57L/J m 815506.0 0.0   1   0.0 0.0 815506.0, 815506.0 -0.6
C58/J m 1942672.0 0.0   1   0.0 0.0 1942672.0, 1942672.0 0.92
CBA/J m 649699.0 0.0   1   0.0 0.0 649699.0, 649699.0 -0.82
CE/J m 599892.0 0.0   1   0.0 0.0 599892.0, 599892.0 -0.89
CXB11/HiAJ m 1238864.0 579355.0   2   409666.0 0.468 829198.0, 1648530.0 -0.03
CXB12/HiAJ m 1317110.0 560755.0   2   396514.0 0.426 920596.0, 1713624.0 0.08
CXB13/HiAJ m 1540643.0 923801.0   3 533357.0 0.6 487046.0, 2211864.0 0.38
CXB1/ByJ m 1271114.0 663877.0   3 383289.0 0.522 505185.0, 1681418.0 0.01
CXB2/ByJ m 646785.0 384121.0   3 221772.0 0.594 383612.0, 1087570.0 -0.82
CXB3/ByJ m 1517872.0 896337.0   2   633806.0 0.591 884066.0, 2151678.0 0.34
CXB4/ByJ m 1451863.0 370532.0   2   262005.0 0.255 1189858.0, 1713868.0 0.26
CXB6/ByJ m 997135.0 592915.0   3 342319.0 0.595 438267.0, 1619056.0 -0.35
CXB7/ByJ m 1365507.0 670829.0   2   474348.0 0.491 891159.0, 1839855.0 0.14
CXB8/HiAJ m 1428452.0 335947.0   3 193959.0 0.235 1210989.0, 1815379.0 0.22
CXB9/HiAJ m 713023.0 225912.0   3 130430.0 0.317 452754.0, 858356.0 -0.74
DBA/2J m 1249473.0 542494.0   4 271247.0 0.434 621602.0, 1829886.0 -0.02
FVB/NJ m 2154050.0 0.0   1   0.0 0.0 2154050.0, 2154050.0 1.2
I/LnJ m 1872102.0 0.0   1   0.0 0.0 1872102.0, 1872102.0 0.82
KK/HlJ m 991023.0 0.0   1   0.0 0.0 991023.0, 991023.0 -0.36
LG/J m 4038471.0 0.0   1   0.0 0.0 4038471.0, 4038471.0 3.73
LP/J m 2140219.0 0.0   1   0.0 0.0 2140219.0, 2140219.0 1.18
MA/MyJ m 3488028.0 0.0   1   0.0 0.0 3488028.0, 3488028.0 2.99
NOD/ShiLtJ m 496138.0 0.0   1   0.0 0.0 496138.0, 496138.0 -1.03
NON/ShiLtJ m 2533354.0 0.0   1   0.0 0.0 2533354.0, 2533354.0 1.71
NZW/LacJ m 837981.0 0.0   1   0.0 0.0 837981.0, 837981.0 -0.57
PL/J m 1575284.0 0.0   1   0.0 0.0 1575284.0, 1575284.0 0.42
RIIIS/J m 264676.0 0.0   1   0.0 0.0 264676.0, 264676.0 -1.34
SEA/GnJ m 770206.0 0.0   1   0.0 0.0 770206.0, 770206.0 -0.66
SJL/J m 2017688.0 0.0   1   0.0 0.0 2017688.0, 2017688.0 1.02
SM/J m 1001238.0 0.0   1   0.0 0.0 1001238.0, 1001238.0 -0.35
SWR/J m 1072902.0 0.0   1   0.0 0.0 1072902.0, 1072902.0 -0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 1152910.75 498900.2939 2166798.133 139023.367
AXB19b/PgnJ m 2071221.1 498900.2939 3085108.483 1057333.717
AXB24/PgnJ m 669079.55 498900.2939 1682966.933 0.0
BALB/cJ m 1766153.4333 407350.3842 2593989.015 938317.8516
BXA16/PgnJ m 585453.3 498900.2939 1599340.683 0.0
BXD19/TyJ m 1343102.15 498900.2939 2356989.533 329214.767
BXD28/TyJ m 718004.1 498900.2939 1731891.483 0.0
BXH4/TyJ m 644099.45 498900.2939 1657986.833 0.0
C3H/HeJ m 1134562.05 498900.2939 2148449.433 120674.667
C57BL/6J m 1843428.18 315532.2508 2484666.8643 1202189.4957
CXB11/HiAJ m 1238864.4 498900.2939 2252751.783 224977.017
CXB12/HiAJ m 1317110.0 498900.2939 2330997.383 303222.617
CXB13/HiAJ m 1540643.1667 407350.3842 2368478.7484 712807.585
CXB1/ByJ m 1271113.5 407350.3842 2098949.0817 443277.9183
CXB2/ByJ m 646784.7 407350.3842 1474620.2817 0.0
CXB3/ByJ m 1517871.6 498900.2939 2531758.983 503984.217
CXB4/ByJ m 1451862.9 498900.2939 2465750.283 437975.517
CXB6/ByJ m 997134.8667 407350.3842 1824970.4484 169299.285
CXB7/ByJ m 1365507.1 498900.2939 2379394.483 351619.717
CXB8/HiAJ m 1428452.3667 407350.3842 2256287.9484 600616.785
CXB9/HiAJ m 713023.0667 407350.3842 1540858.6484 0.0
DBA/2J m 1249472.625 352775.781 1966399.2689 532545.9811




  GWAS USING LINEAR MIXED MODELS