Phenotype measure:   HMDPpheno7   malate

ID, description, units MPD:50242   malate   malate (16h fast), relative abundance  
Data set, strains HMDPpheno7   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno7 - malate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means3978155   None
Median of the strain means3941425   None
SD of the strain means± 841063
Coefficient of variation (CV)0.211
Min–max range of strain means2244680   –   6901535   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 7692904018363.92 366328762779.234 1.275 0.258
Residuals 34 9768809573229.02 287317928624.383


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 4919892.0 0.0   1   0.0 0.0 4919892.0, 4919892.0 1.12
A/J m 3165560.0 411052.0   2   290658.0 0.13 2874902.0, 3456217.0 -0.97
AKR/J m 3392097.0 0.0   1   0.0 0.0 3392097.0, 3392097.0 -0.7
AXB10/PgnJ m 3946010.0 0.0   1   0.0 0.0 3946010.0, 3946010.0 -0.04
AXB12/PgnJ m 4151808.0 0.0   1   0.0 0.0 4151808.0, 4151808.0 0.21
AXB13/PgnJ m 3596076.0 0.0   1   0.0 0.0 3596076.0, 3596076.0 -0.45
AXB15/PgnJ m 3452149.0 0.0   1   0.0 0.0 3452149.0, 3452149.0 -0.63
AXB19a/PgnJ m 4517440.0 0.0   1   0.0 0.0 4517440.0, 4517440.0 0.64
AXB19b/PgnJ m 4572764.0 157848.0   2   111615.0 0.0345 4461148.0, 4684380.0 0.71
AXB19/PgnJ m 3681166.0 0.0   1   0.0 0.0 3681166.0, 3681166.0 -0.35
AXB1/PgnJ m 4316766.0 0.0   1   0.0 0.0 4316766.0, 4316766.0 0.4
AXB23/PgnJ m 3223629.0 0.0   1   0.0 0.0 3223629.0, 3223629.0 -0.9
AXB24/PgnJ m 3966870.0 816071.0   2   577050.0 0.206 3389821.0, 4543920.0 -0.01
AXB2/PgnJ m 2682346.0 0.0   1   0.0 0.0 2682346.0, 2682346.0 -1.54
AXB4/PgnJ m 4205657.0 0.0   1   0.0 0.0 4205657.0, 4205657.0 0.27
AXB5/PgnJ m 3096867.0 0.0   1   0.0 0.0 3096867.0, 3096867.0 -1.05
AXB6/PgnJ m 4142132.0 0.0   1   0.0 0.0 4142132.0, 4142132.0 0.19
AXB8/PgnJ m 3615419.0 0.0   1   0.0 0.0 3615419.0, 3615419.0 -0.43
BALB/cJ m 4348823.0 404577.0   3 233583.0 0.093 4050752.0, 4809384.0 0.44
BTBR T+ Itpr3tf/J m 3876680.0 0.0   1   0.0 0.0 3876680.0, 3876680.0 -0.12
BUB/BnJ m 3952589.0 0.0   1   0.0 0.0 3952589.0, 3952589.0 -0.03
BXA11/PgnJ m 3633221.0 0.0   1   0.0 0.0 3633221.0, 3633221.0 -0.41
BXA12/PgnJ m 2244680.0 0.0   1   0.0 0.0 2244680.0, 2244680.0 -2.06
BXA13/PgnJ m 3742804.0 0.0   1   0.0 0.0 3742804.0, 3742804.0 -0.28
BXA14/PgnJ m 6901535.0 0.0   1   0.0 0.0 6901535.0, 6901535.0 3.48
BXA16/PgnJ m 4238350.0 329652.0   2   233099.0 0.0778 4005250.0, 4471449.0 0.31
BXA1/PgnJ m 3173811.0 0.0   1   0.0 0.0 3173811.0, 3173811.0 -0.96
BXA24/PgnJ m 4000009.0 0.0   1   0.0 0.0 4000009.0, 4000009.0 0.03
BXA25/PgnJ m 2677026.0 0.0   1   0.0 0.0 2677026.0, 2677026.0 -1.55
BXA26/PgnJ m 4135904.0 0.0   1   0.0 0.0 4135904.0, 4135904.0 0.19
BXA2/PgnJ m 4182380.0 0.0   1   0.0 0.0 4182380.0, 4182380.0 0.24
BXA4/PgnJ m 3243656.0 0.0   1   0.0 0.0 3243656.0, 3243656.0 -0.87
BXA7/PgnJ m 3516539.0 0.0   1   0.0 0.0 3516539.0, 3516539.0 -0.55
BXA8/PgnJ m 2591093.0 0.0   1   0.0 0.0 2591093.0, 2591093.0 -1.65
BXD11/TyJ m 3329548.0 0.0   1   0.0 0.0 3329548.0, 3329548.0 -0.77
BXD12/TyJ m 4853431.0 0.0   1   0.0 0.0 4853431.0, 4853431.0 1.04
BXD13/TyJ m 4517699.0 0.0   1   0.0 0.0 4517699.0, 4517699.0 0.64
BXD14/TyJ m 5360550.0 0.0   1   0.0 0.0 5360550.0, 5360550.0 1.64
BXD15/TyJ m 3656464.0 0.0   1   0.0 0.0 3656464.0, 3656464.0 -0.38
BXD18/TyJ m 3991309.0 0.0   1   0.0 0.0 3991309.0, 3991309.0 0.02
BXD19/TyJ m 4718622.0 810699.0   2   573251.0 0.172 4145371.0, 5291872.0 0.88
BXD1/TyJ m 3911873.0 0.0   1   0.0 0.0 3911873.0, 3911873.0 -0.08
BXD20/TyJ m 5185058.0 0.0   1   0.0 0.0 5185058.0, 5185058.0 1.43
BXD21/TyJ m 3045100.0 0.0   1   0.0 0.0 3045100.0, 3045100.0 -1.11
BXD22/TyJ m 3569110.0 0.0   1   0.0 0.0 3569110.0, 3569110.0 -0.49
BXD24/TyJ m 3343956.0 0.0   1   0.0 0.0 3343956.0, 3343956.0 -0.75
BXD24/TyJ-Cep290rd16/J m 3853426.0 0.0   1   0.0 0.0 3853426.0, 3853426.0 -0.15
BXD28/TyJ m 3924348.0 406896.0   2   287719.0 0.104 3636630.0, 4212068.0 -0.06
BXD29-Tlr4lps-2J/J m 4125043.0 0.0   1   0.0 0.0 4125043.0, 4125043.0 0.17
BXD2/TyJ m 5019022.0 0.0   1   0.0 0.0 5019022.0, 5019022.0 1.24
BXD32/TyJ m 3620046.0 0.0   1   0.0 0.0 3620046.0, 3620046.0 -0.43
BXD33/TyJ m 6549928.0 0.0   1   0.0 0.0 6549928.0, 6549928.0 3.06
BXD34/TyJ m 2487046.0 0.0   1   0.0 0.0 2487046.0, 2487046.0 -1.77
BXD36/TyJ m 4410412.0 0.0   1   0.0 0.0 4410412.0, 4410412.0 0.51
BXD38/TyJ m 3003460.0 0.0   1   0.0 0.0 3003460.0, 3003460.0 -1.16
BXD39/TyJ m 3226239.0 0.0   1   0.0 0.0 3226239.0, 3226239.0 -0.89
BXD40/TyJ m 4133734.0 0.0   1   0.0 0.0 4133734.0, 4133734.0 0.18
BXD42/TyJ m 4209454.0 0.0   1   0.0 0.0 4209454.0, 4209454.0 0.28
BXD5/TyJ m 4079326.0 0.0   1   0.0 0.0 4079326.0, 4079326.0 0.12
BXD6/TyJ m 4704248.0 0.0   1   0.0 0.0 4704248.0, 4704248.0 0.86
BXD8/TyJ m 4316944.0 0.0   1   0.0 0.0 4316944.0, 4316944.0 0.4
BXD9/TyJ m 4123056.0 0.0   1   0.0 0.0 4123056.0, 4123056.0 0.17
BXH10/TyJ m 3056610.0 0.0   1   0.0 0.0 3056610.0, 3056610.0 -1.1
BXH19/TyJ m 3157706.0 0.0   1   0.0 0.0 3157706.0, 3157706.0 -0.98
BXH20/KccJ m 4590737.0 0.0   1   0.0 0.0 4590737.0, 4590737.0 0.73
BXH22/KccJ m 3677992.0 0.0   1   0.0 0.0 3677992.0, 3677992.0 -0.36
BXH2/TyJ m 4166980.0 0.0   1   0.0 0.0 4166980.0, 4166980.0 0.22
BXH4/TyJ m 3711643.0 29089.0   2   20569.0 0.00784 3691074.0, 3732212.0 -0.32
BXH6/TyJ m 4068220.0 0.0   1   0.0 0.0 4068220.0, 4068220.0 0.11
BXH7/TyJ m 4503614.0 0.0   1   0.0 0.0 4503614.0, 4503614.0 0.62
BXH8/TyJ m 4563644.0 0.0   1   0.0 0.0 4563644.0, 4563644.0 0.7
BXH9/TyJ m 2861374.0 0.0   1   0.0 0.0 2861374.0, 2861374.0 -1.33
C3H/HeJ m 3944722.0 652350.0   2   461281.0 0.165 3483441.0, 4406003.0 -0.04
C57BL/6J m 3784429.0 293978.0   5 131471.0 0.0777 3337230.0, 4155543.0 -0.23
C57L/J m 3194344.0 0.0   1   0.0 0.0 3194344.0, 3194344.0 -0.93
C58/J m 6435189.0 0.0   1   0.0 0.0 6435189.0, 6435189.0 2.92
CAST/EiJ m 6397072.0 0.0   1   0.0 0.0 6397072.0, 6397072.0 2.88
CBA/J m 3342435.0 0.0   1   0.0 0.0 3342435.0, 3342435.0 -0.76
CE/J m 3505464.0 0.0   1   0.0 0.0 3505464.0, 3505464.0 -0.56
CXB11/HiAJ m 3445884.0 1312481.0   2   928064.0 0.381 2517820.0, 4373948.0 -0.63
CXB12/HiAJ m 3820993.0 341032.0   2   241146.0 0.0893 3579848.0, 4062139.0 -0.19
CXB13/HiAJ m 4608696.0 135480.0   3 78219.0 0.0294 4492966.0, 4757718.0 0.75
CXB1/ByJ m 4537681.0 831743.0   3 480207.0 0.183 4040696.0, 5497898.0 0.67
CXB2/ByJ m 3858191.0 114771.0   3 66263.0 0.0297 3755964.0, 3982344.0 -0.14
CXB3/ByJ m 3942613.0 453303.0   2   320534.0 0.115 3622080.0, 4263146.0 -0.04
CXB4/ByJ m 4263344.0 47139.0   2   33332.0 0.0111 4230012.0, 4296676.0 0.34
CXB6/ByJ m 3940237.0 1002848.0   3 578995.0 0.255 3302177.0, 5096145.0 -0.05
CXB7/ByJ m 3877107.0 667180.0   2   471767.0 0.172 3405339.0, 4348874.0 -0.12
CXB8/HiAJ m 4142172.0 527502.0   3 304553.0 0.127 3543491.0, 4538695.0 0.2
CXB9/HiAJ m 3521305.0 80968.0   3 46747.0 0.023 3439064.0, 3600937.0 -0.54
DBA/2J m 3871052.0 345734.0   4 172867.0 0.0893 3368238.0, 4156526.0 -0.13
FVB/NJ m 5439817.0 0.0   1   0.0 0.0 5439817.0, 5439817.0 1.74
I/LnJ m 4758180.0 0.0   1   0.0 0.0 4758180.0, 4758180.0 0.93
KK/HlJ m 3466674.0 0.0   1   0.0 0.0 3466674.0, 3466674.0 -0.61
LG/J m 2781215.0 0.0   1   0.0 0.0 2781215.0, 2781215.0 -1.42
LP/J m 4492364.0 0.0   1   0.0 0.0 4492364.0, 4492364.0 0.61
MA/MyJ m 3943889.0 0.0   1   0.0 0.0 3943889.0, 3943889.0 -0.04
NOD/ShiLtJ m 3148184.0 0.0   1   0.0 0.0 3148184.0, 3148184.0 -0.99
NON/ShiLtJ m 3654005.0 0.0   1   0.0 0.0 3654005.0, 3654005.0 -0.39
NZW/LacJ m 3528878.0 0.0   1   0.0 0.0 3528878.0, 3528878.0 -0.53
PL/J m 4180612.0 0.0   1   0.0 0.0 4180612.0, 4180612.0 0.24
RIIIS/J m 2536452.0 0.0   1   0.0 0.0 2536452.0, 2536452.0 -1.71
SEA/GnJ m 4216117.0 0.0   1   0.0 0.0 4216117.0, 4216117.0 0.28
SJL/J m 3422320.0 0.0   1   0.0 0.0 3422320.0, 3422320.0 -0.66
SM/J m 5198006.0 0.0   1   0.0 0.0 5198006.0, 5198006.0 1.45
SWR/J m 5754016.0 0.0   1   0.0 0.0 5754016.0, 5754016.0 2.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 3165559.65 379023.6989 3935828.4809 2395290.8191
AXB19b/PgnJ m 4572764.0 379023.6989 5343032.8309 3802495.1691
AXB24/PgnJ m 3966870.4 379023.6989 4737139.2309 3196601.5691
BALB/cJ m 4348823.1667 309471.5542 4977745.0335 3719901.2998
BXA16/PgnJ m 4238349.65 379023.6989 5008618.4809 3468080.8191
BXD19/TyJ m 4718621.65 379023.6989 5488890.4809 3948352.8191
BXD28/TyJ m 3924348.5 379023.6989 4694617.3309 3154079.6691
BXH4/TyJ m 3711643.0 379023.6989 4481911.8309 2941374.1691
C3H/HeJ m 3944722.0 379023.6989 4714990.8309 3174453.1691
C57BL/6J m 3784428.72 239715.6351 4271589.5033 3297267.9367
CXB11/HiAJ m 3445883.75 379023.6989 4216152.5809 2675614.9191
CXB12/HiAJ m 3820993.25 379023.6989 4591262.0809 3050724.4191
CXB13/HiAJ m 4608696.0 309471.5542 5237617.8669 3979774.1331
CXB1/ByJ m 4537680.9333 309471.5542 5166602.8002 3908759.0665
CXB2/ByJ m 3858190.6667 309471.5542 4487112.5335 3229268.7998
CXB3/ByJ m 3942613.0 379023.6989 4712881.8309 3172344.1691
CXB4/ByJ m 4263344.0 379023.6989 5033612.8309 3493075.1691
CXB6/ByJ m 3940237.3667 309471.5542 4569159.2335 3311315.4998
CXB7/ByJ m 3877106.65 379023.6989 4647375.4809 3106837.8191
CXB8/HiAJ m 4142171.5 309471.5542 4771093.3669 3513249.6331
CXB9/HiAJ m 3521304.9333 309471.5542 4150226.8002 2892383.0665
DBA/2J m 3871052.075 268010.2277 4415714.3887 3326389.7613




  GWAS USING LINEAR MIXED MODELS