Phenotype measure:   HMDPpheno7   nicotinamide

ID, description, units MPD:50232   nicotinamide   liver nicotinamide (16h fast), relative abundance  
Data set, strains HMDPpheno7   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno7 - liver nicotinamide (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means7728549   None
Median of the strain means7676008   None
SD of the strain means± 1560775
Coefficient of variation (CV)0.202
Min–max range of strain means3955419   –   13806594   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 79063559331120.4 3764931396720.02 3.1897 0.0013
Residuals 34 40131460612606.8 1180337076841.38


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 7155529.0 0.0   1   0.0 0.0 7155529.0, 7155529.0 -0.37
A/J m 7821689.0 282824.0   2   199986.0 0.0362 7621702.0, 8021676.0 0.06
AKR/J m 8126412.0 0.0   1   0.0 0.0 8126412.0, 8126412.0 0.25
AXB10/PgnJ m 7495432.0 0.0   1   0.0 0.0 7495432.0, 7495432.0 -0.15
AXB12/PgnJ m 7093628.0 0.0   1   0.0 0.0 7093628.0, 7093628.0 -0.41
AXB13/PgnJ m 7507380.0 0.0   1   0.0 0.0 7507380.0, 7507380.0 -0.14
AXB15/PgnJ m 7847516.0 0.0   1   0.0 0.0 7847516.0, 7847516.0 0.08
AXB19a/PgnJ m 8919866.0 0.0   1   0.0 0.0 8919866.0, 8919866.0 0.76
AXB19b/PgnJ m 11141012.0 2594151.0   2   1834342.0 0.233 9306670.0, 12975354.0 2.19
AXB19/PgnJ m 10870443.0 0.0   1   0.0 0.0 10870443.0, 10870443.0 2.01
AXB1/PgnJ m 7451436.0 0.0   1   0.0 0.0 7451436.0, 7451436.0 -0.18
AXB23/PgnJ m 6746587.0 0.0   1   0.0 0.0 6746587.0, 6746587.0 -0.63
AXB24/PgnJ m 8071317.0 2581934.0   2   1825703.0 0.32 6245614.0, 9897020.0 0.22
AXB2/PgnJ m 6213414.0 0.0   1   0.0 0.0 6213414.0, 6213414.0 -0.97
AXB4/PgnJ m 8383020.0 0.0   1   0.0 0.0 8383020.0, 8383020.0 0.42
AXB5/PgnJ m 7347237.0 0.0   1   0.0 0.0 7347237.0, 7347237.0 -0.24
AXB6/PgnJ m 8495830.0 0.0   1   0.0 0.0 8495830.0, 8495830.0 0.49
AXB8/PgnJ m 6961861.0 0.0   1   0.0 0.0 6961861.0, 6961861.0 -0.49
BALB/cJ m 6991282.0 1480632.0   3 854843.0 0.212 5779668.0, 8641725.0 -0.47
BTBR T+ Itpr3tf/J m 6924125.0 0.0   1   0.0 0.0 6924125.0, 6924125.0 -0.52
BUB/BnJ m 7457531.0 0.0   1   0.0 0.0 7457531.0, 7457531.0 -0.17
BXA11/PgnJ m 6286657.0 0.0   1   0.0 0.0 6286657.0, 6286657.0 -0.92
BXA12/PgnJ m 3955419.0 0.0   1   0.0 0.0 3955419.0, 3955419.0 -2.42
BXA13/PgnJ m 6929311.0 0.0   1   0.0 0.0 6929311.0, 6929311.0 -0.51
BXA14/PgnJ m 13806594.0 0.0   1   0.0 0.0 13806594.0, 13806594.0 3.89
BXA16/PgnJ m 8231308.0 2244413.0   2   1587040.0 0.273 6644268.0, 9818348.0 0.32
BXA1/PgnJ m 9109592.0 0.0   1   0.0 0.0 9109592.0, 9109592.0 0.88
BXA24/PgnJ m 8795063.0 0.0   1   0.0 0.0 8795063.0, 8795063.0 0.68
BXA25/PgnJ m 7699463.0 0.0   1   0.0 0.0 7699463.0, 7699463.0 -0.02
BXA26/PgnJ m 6589894.0 0.0   1   0.0 0.0 6589894.0, 6589894.0 -0.73
BXA2/PgnJ m 9281356.0 0.0   1   0.0 0.0 9281356.0, 9281356.0 0.99
BXA4/PgnJ m 6461068.0 0.0   1   0.0 0.0 6461068.0, 6461068.0 -0.81
BXA7/PgnJ m 8234772.0 0.0   1   0.0 0.0 8234772.0, 8234772.0 0.32
BXA8/PgnJ m 7565126.0 0.0   1   0.0 0.0 7565126.0, 7565126.0 -0.1
BXD11/TyJ m 4562459.0 0.0   1   0.0 0.0 4562459.0, 4562459.0 -2.03
BXD12/TyJ m 7716867.0 0.0   1   0.0 0.0 7716867.0, 7716867.0 -0.01
BXD13/TyJ m 8289844.0 0.0   1   0.0 0.0 8289844.0, 8289844.0 0.36
BXD14/TyJ m 8420978.0 0.0   1   0.0 0.0 8420978.0, 8420978.0 0.44
BXD15/TyJ m 7871291.0 0.0   1   0.0 0.0 7871291.0, 7871291.0 0.09
BXD18/TyJ m 6697326.0 0.0   1   0.0 0.0 6697326.0, 6697326.0 -0.66
BXD19/TyJ m 7115325.0 296446.0   2   209619.0 0.0417 6905706.0, 7324944.0 -0.39
BXD1/TyJ m 7328154.0 0.0   1   0.0 0.0 7328154.0, 7328154.0 -0.26
BXD20/TyJ m 9240658.0 0.0   1   0.0 0.0 9240658.0, 9240658.0 0.97
BXD21/TyJ m 6349444.0 0.0   1   0.0 0.0 6349444.0, 6349444.0 -0.88
BXD22/TyJ m 9141461.0 0.0   1   0.0 0.0 9141461.0, 9141461.0 0.91
BXD24/TyJ m 6658188.0 0.0   1   0.0 0.0 6658188.0, 6658188.0 -0.69
BXD24/TyJ-Cep290rd16/J m 6084732.0 0.0   1   0.0 0.0 6084732.0, 6084732.0 -1.05
BXD28/TyJ m 8567938.0 738456.0   2   522167.0 0.0862 8045770.0, 9090105.0 0.54
BXD29-Tlr4lps-2J/J m 7060560.0 0.0   1   0.0 0.0 7060560.0, 7060560.0 -0.43
BXD2/TyJ m 6605024.0 0.0   1   0.0 0.0 6605024.0, 6605024.0 -0.72
BXD32/TyJ m 8577995.0 0.0   1   0.0 0.0 8577995.0, 8577995.0 0.54
BXD33/TyJ m 8359780.0 0.0   1   0.0 0.0 8359780.0, 8359780.0 0.4
BXD34/TyJ m 5636402.0 0.0   1   0.0 0.0 5636402.0, 5636402.0 -1.34
BXD36/TyJ m 5152054.0 0.0   1   0.0 0.0 5152054.0, 5152054.0 -1.65
BXD38/TyJ m 4600561.0 0.0   1   0.0 0.0 4600561.0, 4600561.0 -2.0
BXD39/TyJ m 9549035.0 0.0   1   0.0 0.0 9549035.0, 9549035.0 1.17
BXD40/TyJ m 6417766.0 0.0   1   0.0 0.0 6417766.0, 6417766.0 -0.84
BXD42/TyJ m 7226228.0 0.0   1   0.0 0.0 7226228.0, 7226228.0 -0.32
BXD5/TyJ m 9034349.0 0.0   1   0.0 0.0 9034349.0, 9034349.0 0.84
BXD6/TyJ m 7954722.0 0.0   1   0.0 0.0 7954722.0, 7954722.0 0.14
BXD8/TyJ m 5548335.0 0.0   1   0.0 0.0 5548335.0, 5548335.0 -1.4
BXD9/TyJ m 7137169.0 0.0   1   0.0 0.0 7137169.0, 7137169.0 -0.38
BXH10/TyJ m 7766618.0 0.0   1   0.0 0.0 7766618.0, 7766618.0 0.02
BXH19/TyJ m 8437730.0 0.0   1   0.0 0.0 8437730.0, 8437730.0 0.45
BXH20/KccJ m 9399751.0 0.0   1   0.0 0.0 9399751.0, 9399751.0 1.07
BXH22/KccJ m 7697379.0 0.0   1   0.0 0.0 7697379.0, 7697379.0 -0.02
BXH2/TyJ m 10103340.0 0.0   1   0.0 0.0 10103340.0, 10103340.0 1.52
BXH4/TyJ m 9157088.0 268978.0   2   190196.0 0.0294 8966892.0, 9347284.0 0.92
BXH6/TyJ m 11705604.0 0.0   1   0.0 0.0 11705604.0, 11705604.0 2.55
BXH7/TyJ m 6256498.0 0.0   1   0.0 0.0 6256498.0, 6256498.0 -0.94
BXH8/TyJ m 9407223.0 0.0   1   0.0 0.0 9407223.0, 9407223.0 1.08
BXH9/TyJ m 7329346.0 0.0   1   0.0 0.0 7329346.0, 7329346.0 -0.26
C3H/HeJ m 8263458.0 1403748.0   2   992600.0 0.17 7270858.0, 9256057.0 0.34
C57BL/6J m 6872864.0 1053117.0   5 470968.0 0.153 5148150.0, 7842249.0 -0.55
C57L/J m 5365483.0 0.0   1   0.0 0.0 5365483.0, 5365483.0 -1.51
C58/J m 11350278.0 0.0   1   0.0 0.0 11350278.0, 11350278.0 2.32
CAST/EiJ m 7139291.0 0.0   1   0.0 0.0 7139291.0, 7139291.0 -0.38
CBA/J m 7071336.0 0.0   1   0.0 0.0 7071336.0, 7071336.0 -0.42
CE/J m 8002316.0 0.0   1   0.0 0.0 8002316.0, 8002316.0 0.18
CXB11/HiAJ m 7007984.0 1007117.0   2   712139.0 0.144 6295846.0, 7720124.0 -0.46
CXB12/HiAJ m 7920904.0 708730.0   2   501148.0 0.0895 7419756.0, 8422052.0 0.12
CXB13/HiAJ m 7128676.0 435738.0   3 251574.0 0.0611 6760508.0, 7609756.0 -0.38
CXB1/ByJ m 8700607.0 681206.0   3 393295.0 0.0783 8057574.0, 9414454.0 0.62
CXB2/ByJ m 8436476.0 934492.0   3 539529.0 0.111 7468584.0, 9333537.0 0.45
CXB3/ByJ m 7862515.0 274465.0   2   194076.0 0.0349 7668439.0, 8056592.0 0.09
CXB4/ByJ m 10716304.0 749297.0   2   529833.0 0.0699 10186471.0, 11246137.0 1.91
CXB6/ByJ m 7170551.0 241070.0   3 139182.0 0.0336 7021952.0, 7448696.0 -0.36
CXB7/ByJ m 8826977.0 778408.0   2   550417.0 0.0882 8276560.0, 9377394.0 0.7
CXB8/HiAJ m 8170912.0 738727.0   3 426504.0 0.0904 7359278.0, 8804006.0 0.28
CXB9/HiAJ m 7654638.0 586305.0   3 338503.0 0.0766 7228472.0, 8323286.0 -0.05
DBA/2J m 5735848.0 896742.0   4 448371.0 0.156 4908020.0, 7001930.0 -1.28
FVB/NJ m 6898084.0 0.0   1   0.0 0.0 6898084.0, 6898084.0 -0.53
I/LnJ m 7246912.0 0.0   1   0.0 0.0 7246912.0, 7246912.0 -0.31
KK/HlJ m 6154142.0 0.0   1   0.0 0.0 6154142.0, 6154142.0 -1.01
LG/J m 11512392.0 0.0   1   0.0 0.0 11512392.0, 11512392.0 2.42
LP/J m 7964491.0 0.0   1   0.0 0.0 7964491.0, 7964491.0 0.15
MA/MyJ m 5994314.0 0.0   1   0.0 0.0 5994314.0, 5994314.0 -1.11
NOD/ShiLtJ m 7021536.0 0.0   1   0.0 0.0 7021536.0, 7021536.0 -0.45
NON/ShiLtJ m 5850906.0 0.0   1   0.0 0.0 5850906.0, 5850906.0 -1.2
NZW/LacJ m 7748576.0 0.0   1   0.0 0.0 7748576.0, 7748576.0 0.01
PL/J m 7806280.0 0.0   1   0.0 0.0 7806280.0, 7806280.0 0.05
RIIIS/J m 8717891.0 0.0   1   0.0 0.0 8717891.0, 8717891.0 0.63
SEA/GnJ m 6728650.0 0.0   1   0.0 0.0 6728650.0, 6728650.0 -0.64
SJL/J m 8259218.0 0.0   1   0.0 0.0 8259218.0, 8259218.0 0.34
SM/J m 5214990.0 0.0   1   0.0 0.0 5214990.0, 5214990.0 -1.61
SWR/J m 8577039.0 0.0   1   0.0 0.0 8577039.0, 8577039.0 0.54


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 7821689.0 768224.2761 9382908.5671 6260469.4329
AXB19b/PgnJ m 11141012.0 768224.2761 12702231.5671 9579792.4329
AXB24/PgnJ m 8071317.0 768224.2761 9632536.5671 6510097.4329
BALB/cJ m 6991281.8333 627252.4948 8266012.2719 5716551.3947
BXA16/PgnJ m 8231308.0 768224.2761 9792527.5671 6670088.4329
BXD19/TyJ m 7115324.75 768224.2761 8676544.3171 5554105.1829
BXD28/TyJ m 8567937.75 768224.2761 10129157.3171 7006718.1829
BXH4/TyJ m 9157088.0 768224.2761 10718307.5671 7595868.4329
C3H/HeJ m 8263457.5 768224.2761 9824677.0671 6702237.9329
C57BL/6J m 6872864.3 485867.6933 7860266.2519 5885462.3481
CXB11/HiAJ m 7007984.5 768224.2761 8569204.0671 5446764.9329
CXB12/HiAJ m 7920904.25 768224.2761 9482123.8171 6359684.6829
CXB13/HiAJ m 7128675.5 627252.4948 8403405.9386 5853945.0614
CXB1/ByJ m 8700606.8333 627252.4948 9975337.2719 7425876.3947
CXB2/ByJ m 8436475.8333 627252.4948 9711206.2719 7161745.3947
CXB3/ByJ m 7862515.25 768224.2761 9423734.8171 6301295.6829
CXB4/ByJ m 10716304.0 768224.2761 12277523.5671 9155084.4329
CXB6/ByJ m 7170550.6667 627252.4948 8445281.1053 5895820.2281
CXB7/ByJ m 8826976.75 768224.2761 10388196.3171 7265757.1829
CXB8/HiAJ m 8170912.0 627252.4948 9445642.4386 6896181.5614
CXB9/HiAJ m 7654637.8333 627252.4948 8929368.2719 6379907.3947
DBA/2J m 5735847.5 543216.5951 6839796.4428 4631898.5572




  GWAS USING LINEAR MIXED MODELS