Phenotype measure:   HMDPpheno7   MeTHF

ID, description, units MPD:50230   MeTHF   liver 5-methyltetrahydrofolate (5MeTHF) (16h fast), relative abundance  
Data set, strains HMDPpheno7   HMDP   93 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno7 - liver 5-methyltetrahydrofolate (5MeTHF) (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested93 strains
Mean of the strain means22753   None
Median of the strain means21302   None
SD of the strain means± 10377
Coefficient of variation (CV)0.456
Min–max range of strain means4248   –   59933   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 18 3949932644.0611 219440702.4478 2.4396 0.0157
Residuals 29 2608515431.627 89948807.9871


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J m 5136.0 0.0   1   0.0 0.0 5136.0, 5136.0 -1.7
AKR/J m 10158.0 0.0   1   0.0 0.0 10158.0, 10158.0 -1.21
AXB12/PgnJ m 19618.0 0.0   1   0.0 0.0 19618.0, 19618.0 -0.3
AXB13/PgnJ m 35958.0 0.0   1   0.0 0.0 35958.0, 35958.0 1.27
AXB15/PgnJ m 16551.0 0.0   1   0.0 0.0 16551.0, 16551.0 -0.6
AXB19a/PgnJ m 11896.0 0.0   1   0.0 0.0 11896.0, 11896.0 -1.05
AXB19b/PgnJ m 21123.0 3721.0   2   2631.0 0.176 18492.0, 23754.0 -0.16
AXB19/PgnJ m 19222.0 0.0   1   0.0 0.0 19222.0, 19222.0 -0.34
AXB1/PgnJ m 15200.0 0.0   1   0.0 0.0 15200.0, 15200.0 -0.73
AXB23/PgnJ m 18404.0 0.0   1   0.0 0.0 18404.0, 18404.0 -0.42
AXB24/PgnJ m 21302.0 10153.0   2   7179.0 0.477 14123.0, 28481.0 -0.14
AXB2/PgnJ m 22081.0 0.0   1   0.0 0.0 22081.0, 22081.0 -0.06
AXB4/PgnJ m 9939.0 0.0   1   0.0 0.0 9939.0, 9939.0 -1.23
AXB5/PgnJ m 21371.0 0.0   1   0.0 0.0 21371.0, 21371.0 -0.13
AXB6/PgnJ m 22081.0 0.0   1   0.0 0.0 22081.0, 22081.0 -0.06
AXB8/PgnJ m 20098.0 0.0   1   0.0 0.0 20098.0, 20098.0 -0.26
BALB/cJ m 18651.0 871.0   3 503.0 0.0467 17787.0, 19530.0 -0.4
BUB/BnJ m 16956.0 0.0   1   0.0 0.0 16956.0, 16956.0 -0.56
BXA11/PgnJ m 28920.0 0.0   1   0.0 0.0 28920.0, 28920.0 0.59
BXA13/PgnJ m 26335.0 0.0   1   0.0 0.0 26335.0, 26335.0 0.35
BXA14/PgnJ m 22081.0 0.0   1   0.0 0.0 22081.0, 22081.0 -0.06
BXA16/PgnJ m 8128.0 0.0   1   0.0 0.0 8128.0, 8128.0 -1.41
BXA1/PgnJ m 59933.0 0.0   1   0.0 0.0 59933.0, 59933.0 3.58
BXA24/PgnJ m 39258.0 0.0   1   0.0 0.0 39258.0, 39258.0 1.59
BXA26/PgnJ m 37087.0 0.0   1   0.0 0.0 37087.0, 37087.0 1.38
BXA2/PgnJ m 31565.0 0.0   1   0.0 0.0 31565.0, 31565.0 0.85
BXA7/PgnJ m 32891.0 0.0   1   0.0 0.0 32891.0, 32891.0 0.98
BXA8/PgnJ m 16509.0 0.0   1   0.0 0.0 16509.0, 16509.0 -0.6
BXD11/TyJ m 22081.0 0.0   1   0.0 0.0 22081.0, 22081.0 -0.06
BXD12/TyJ m 32481.0 0.0   1   0.0 0.0 32481.0, 32481.0 0.94
BXD14/TyJ m 30842.0 0.0   1   0.0 0.0 30842.0, 30842.0 0.78
BXD18/TyJ m 13134.0 0.0   1   0.0 0.0 13134.0, 13134.0 -0.93
BXD19/TyJ m 23365.0 11965.0   2   8461.0 0.512 14905.0, 31826.0 0.06
BXD1/TyJ m 14305.0 0.0   1   0.0 0.0 14305.0, 14305.0 -0.81
BXD20/TyJ m 14720.0 0.0   1   0.0 0.0 14720.0, 14720.0 -0.77
BXD21/TyJ m 32665.0 0.0   1   0.0 0.0 32665.0, 32665.0 0.96
BXD22/TyJ m 37128.0 0.0   1   0.0 0.0 37128.0, 37128.0 1.39
BXD24/TyJ m 25670.0 0.0   1   0.0 0.0 25670.0, 25670.0 0.28
BXD28/TyJ m 28437.0 3095.0   2   2189.0 0.109 26248.0, 30626.0 0.55
BXD29-Tlr4lps-2J/J m 22013.0 0.0   1   0.0 0.0 22013.0, 22013.0 -0.07
BXD2/TyJ m 24509.0 0.0   1   0.0 0.0 24509.0, 24509.0 0.17
BXD32/TyJ m 24256.0 0.0   1   0.0 0.0 24256.0, 24256.0 0.14
BXD33/TyJ m 18000.0 0.0   1   0.0 0.0 18000.0, 18000.0 -0.46
BXD34/TyJ m 21023.0 0.0   1   0.0 0.0 21023.0, 21023.0 -0.17
BXD36/TyJ m 4248.0 0.0   1   0.0 0.0 4248.0, 4248.0 -1.78
BXD38/TyJ m 9102.0 0.0   1   0.0 0.0 9102.0, 9102.0 -1.32
BXD39/TyJ m 23472.0 0.0   1   0.0 0.0 23472.0, 23472.0 0.07
BXD40/TyJ m 25640.0 0.0   1   0.0 0.0 25640.0, 25640.0 0.28
BXD42/TyJ m 14483.0 0.0   1   0.0 0.0 14483.0, 14483.0 -0.8
BXD5/TyJ m 29160.0 0.0   1   0.0 0.0 29160.0, 29160.0 0.62
BXD6/TyJ m 16091.0 0.0   1   0.0 0.0 16091.0, 16091.0 -0.64
BXD8/TyJ m 9908.0 0.0   1   0.0 0.0 9908.0, 9908.0 -1.24
BXD9/TyJ m 37253.0 0.0   1   0.0 0.0 37253.0, 37253.0 1.4
BXH10/TyJ m 29247.0 0.0   1   0.0 0.0 29247.0, 29247.0 0.63
BXH20/KccJ m 20494.0 0.0   1   0.0 0.0 20494.0, 20494.0 -0.22
BXH22/KccJ m 41462.0 0.0   1   0.0 0.0 41462.0, 41462.0 1.8
BXH2/TyJ m 54399.0 0.0   1   0.0 0.0 54399.0, 54399.0 3.05
BXH4/TyJ m 33680.0 1594.0   2   1127.0 0.0473 32553.0, 34807.0 1.05
BXH6/TyJ m 18750.0 0.0   1   0.0 0.0 18750.0, 18750.0 -0.39
BXH7/TyJ m 24870.0 0.0   1   0.0 0.0 24870.0, 24870.0 0.2
BXH8/TyJ m 19778.0 0.0   1   0.0 0.0 19778.0, 19778.0 -0.29
BXH9/TyJ m 4440.0 0.0   1   0.0 0.0 4440.0, 4440.0 -1.76
C3H/HeJ m 24887.0 2471.0   2   1747.0 0.0993 23139.0, 26634.0 0.21
C57BL/6J m 17679.0 5100.0   5 2281.0 0.288 14315.0, 26641.0 -0.49
C57L/J m 14682.0 0.0   1   0.0 0.0 14682.0, 14682.0 -0.78
C58/J m 18053.0 0.0   1   0.0 0.0 18053.0, 18053.0 -0.45
CAST/EiJ m 22459.0 0.0   1   0.0 0.0 22459.0, 22459.0 -0.03
CBA/J m 18086.0 0.0   1   0.0 0.0 18086.0, 18086.0 -0.45
CE/J m 11476.0 0.0   1   0.0 0.0 11476.0, 11476.0 -1.09
CXB11/HiAJ m 20763.0 13519.0   2   9560.0 0.651 11204.0, 30323.0 -0.19
CXB12/HiAJ m 26670.0 27105.0   2   19166.0 1.02 7504.0, 45837.0 0.38
CXB13/HiAJ m 21241.0 8346.0   2   5901.0 0.393 15340.0, 27143.0 -0.15
CXB1/ByJ m 31070.0 7986.0   3 4610.0 0.257 25072.0, 40134.0 0.8
CXB2/ByJ m 16796.0 13544.0   2   9577.0 0.806 7219.0, 26373.0 -0.57
CXB3/ByJ m 26941.0 0.0   1   0.0 0.0 26941.0, 26941.0 0.4
CXB4/ByJ m 21727.0 12536.0   2   8864.0 0.577 12863.0, 30591.0 -0.1
CXB6/ByJ m 33194.0 9559.0   3 5519.0 0.288 23209.0, 42262.0 1.01
CXB7/ByJ m 52085.0 9487.0   2   6708.0 0.182 45377.0, 58794.0 2.83
CXB8/HiAJ m 36410.0 10708.0   3 6182.0 0.294 26759.0, 47929.0 1.32
CXB9/HiAJ m 37501.0 9411.0   3 5433.0 0.251 29704.0, 47954.0 1.42
DBA/2J m 13923.0 5484.0   4 2742.0 0.394 10843.0, 22115.0 -0.85
I/LnJ m 12284.0 0.0   1   0.0 0.0 12284.0, 12284.0 -1.01
KK/HlJ m 9674.0 0.0   1   0.0 0.0 9674.0, 9674.0 -1.26
MA/MyJ m 15220.0 0.0   1   0.0 0.0 15220.0, 15220.0 -0.73
NOD/ShiLtJ m 10689.0 0.0   1   0.0 0.0 10689.0, 10689.0 -1.16
NON/ShiLtJ m 23449.0 0.0   1   0.0 0.0 23449.0, 23449.0 0.07
NZW/LacJ m 12998.0 0.0   1   0.0 0.0 12998.0, 12998.0 -0.94
PL/J m 19335.0 0.0   1   0.0 0.0 19335.0, 19335.0 -0.33
RIIIS/J m 34299.0 0.0   1   0.0 0.0 34299.0, 34299.0 1.11
SEA/GnJ m 28600.0 0.0   1   0.0 0.0 28600.0, 28600.0 0.56
SJL/J m 17043.0 0.0   1   0.0 0.0 17043.0, 17043.0 -0.55
SM/J m 14653.0 0.0   1   0.0 0.0 14653.0, 14653.0 -0.78
SWR/J m 22628.0 0.0   1   0.0 0.0 22628.0, 22628.0 -0.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
AXB19b/PgnJ m 21122.55 6706.2958 34838.4651 7406.6349
AXB24/PgnJ m 21302.15 6706.2958 35018.0651 7586.2349
BALB/cJ m 18651.3 5475.6676 29850.2977 7452.3023
BXD19/TyJ m 23365.25 6706.2958 37081.1651 9649.3349
BXD28/TyJ m 28436.75 6706.2958 42152.6651 14720.8349
BXH4/TyJ m 33680.1 6706.2958 47396.0151 19964.1849
C3H/HeJ m 24886.55 6706.2958 38602.4651 11170.6349
C57BL/6J m 17679.44 4241.4339 26354.1464 9004.7336
CXB11/HiAJ m 20763.25 6706.2958 34479.1651 7047.3349
CXB12/HiAJ m 26670.4 6706.2958 40386.3151 12954.4849
CXB13/HiAJ m 21241.25 6706.2958 34957.1651 7525.3349
CXB1/ByJ m 31069.8333 5475.6676 42268.8311 19870.8356
CXB2/ByJ m 16796.25 6706.2958 30512.1651 3080.3349
CXB4/ByJ m 21727.05 6706.2958 35442.9651 8011.1349
CXB6/ByJ m 33194.4333 5475.6676 44393.4311 21995.4356
CXB7/ByJ m 52085.2 6706.2958 65801.1151 38369.2849
CXB8/HiAJ m 36410.4 5475.6676 47609.3977 25211.4023
CXB9/HiAJ m 37500.8333 5475.6676 48699.8311 26301.8356
DBA/2J m 13922.55 4742.0673 23621.1665 4223.9335




  GWAS USING LINEAR MIXED MODELS