Phenotype measure:   HMDPpheno7   biopterin

ID, description, units MPD:50229   biopterin   liver biopterin (16h fast), relative abundance  
Data set, strains HMDPpheno7   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno7 - liver biopterin (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means112465   None
Median of the strain means110842   None
SD of the strain means± 23612
Coefficient of variation (CV)0.210
Min–max range of strain means56698   –   172480   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 9619127941.5013 458053711.5001 1.4796 0.151
Residuals 34 10525505908.4608 309573703.19


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 84110.0 0.0   1   0.0 0.0 84110.0, 84110.0 -1.2
A/J m 117048.0 13741.0   2   9717.0 0.117 107331.0, 126764.0 0.19
AKR/J m 83049.0 0.0   1   0.0 0.0 83049.0, 83049.0 -1.25
AXB10/PgnJ m 130211.0 0.0   1   0.0 0.0 130211.0, 130211.0 0.75
AXB12/PgnJ m 118205.0 0.0   1   0.0 0.0 118205.0, 118205.0 0.24
AXB13/PgnJ m 118861.0 0.0   1   0.0 0.0 118861.0, 118861.0 0.27
AXB15/PgnJ m 133304.0 0.0   1   0.0 0.0 133304.0, 133304.0 0.88
AXB19a/PgnJ m 140751.0 0.0   1   0.0 0.0 140751.0, 140751.0 1.2
AXB19b/PgnJ m 121974.0 39033.0   2   27600.0 0.32 94373.0, 149574.0 0.4
AXB19/PgnJ m 154433.0 0.0   1   0.0 0.0 154433.0, 154433.0 1.78
AXB1/PgnJ m 104680.0 0.0   1   0.0 0.0 104680.0, 104680.0 -0.33
AXB23/PgnJ m 103631.0 0.0   1   0.0 0.0 103631.0, 103631.0 -0.37
AXB24/PgnJ m 123942.0 6356.0   2   4494.0 0.0513 119448.0, 128436.0 0.49
AXB2/PgnJ m 73492.0 0.0   1   0.0 0.0 73492.0, 73492.0 -1.65
AXB4/PgnJ m 172480.0 0.0   1   0.0 0.0 172480.0, 172480.0 2.54
AXB5/PgnJ m 74416.0 0.0   1   0.0 0.0 74416.0, 74416.0 -1.61
AXB6/PgnJ m 92067.0 0.0   1   0.0 0.0 92067.0, 92067.0 -0.86
AXB8/PgnJ m 155943.0 0.0   1   0.0 0.0 155943.0, 155943.0 1.84
BALB/cJ m 111150.0 22400.0   3 12933.0 0.202 97914.0, 137013.0 -0.06
BTBR T+ Itpr3tf/J m 135472.0 0.0   1   0.0 0.0 135472.0, 135472.0 0.97
BUB/BnJ m 134610.0 0.0   1   0.0 0.0 134610.0, 134610.0 0.94
BXA11/PgnJ m 144891.0 0.0   1   0.0 0.0 144891.0, 144891.0 1.37
BXA12/PgnJ m 95983.0 0.0   1   0.0 0.0 95983.0, 95983.0 -0.7
BXA13/PgnJ m 89684.0 0.0   1   0.0 0.0 89684.0, 89684.0 -0.96
BXA14/PgnJ m 126016.0 0.0   1   0.0 0.0 126016.0, 126016.0 0.57
BXA16/PgnJ m 127518.0 18177.0   2   12853.0 0.143 114664.0, 140371.0 0.64
BXA1/PgnJ m 115542.0 0.0   1   0.0 0.0 115542.0, 115542.0 0.13
BXA24/PgnJ m 101672.0 0.0   1   0.0 0.0 101672.0, 101672.0 -0.46
BXA25/PgnJ m 120928.0 0.0   1   0.0 0.0 120928.0, 120928.0 0.36
BXA26/PgnJ m 85705.0 0.0   1   0.0 0.0 85705.0, 85705.0 -1.13
BXA2/PgnJ m 90283.0 0.0   1   0.0 0.0 90283.0, 90283.0 -0.94
BXA4/PgnJ m 111862.0 0.0   1   0.0 0.0 111862.0, 111862.0 -0.03
BXA7/PgnJ m 105398.0 0.0   1   0.0 0.0 105398.0, 105398.0 -0.3
BXA8/PgnJ m 77029.0 0.0   1   0.0 0.0 77029.0, 77029.0 -1.5
BXD11/TyJ m 97267.0 0.0   1   0.0 0.0 97267.0, 97267.0 -0.64
BXD12/TyJ m 89326.0 0.0   1   0.0 0.0 89326.0, 89326.0 -0.98
BXD13/TyJ m 144710.0 0.0   1   0.0 0.0 144710.0, 144710.0 1.37
BXD14/TyJ m 124922.0 0.0   1   0.0 0.0 124922.0, 124922.0 0.53
BXD15/TyJ m 99970.0 0.0   1   0.0 0.0 99970.0, 99970.0 -0.53
BXD18/TyJ m 114061.0 0.0   1   0.0 0.0 114061.0, 114061.0 0.07
BXD19/TyJ m 98807.0 20260.0   2   14326.0 0.205 84481.0, 113134.0 -0.58
BXD1/TyJ m 93104.0 0.0   1   0.0 0.0 93104.0, 93104.0 -0.82
BXD20/TyJ m 93864.0 0.0   1   0.0 0.0 93864.0, 93864.0 -0.79
BXD21/TyJ m 96605.0 0.0   1   0.0 0.0 96605.0, 96605.0 -0.67
BXD22/TyJ m 104708.0 0.0   1   0.0 0.0 104708.0, 104708.0 -0.33
BXD24/TyJ m 109300.0 0.0   1   0.0 0.0 109300.0, 109300.0 -0.13
BXD24/TyJ-Cep290rd16/J m 142664.0 0.0   1   0.0 0.0 142664.0, 142664.0 1.28
BXD28/TyJ m 103794.0 140.0   2   99.3 0.00135 103695.0, 103894.0 -0.37
BXD29-Tlr4lps-2J/J m 78553.0 0.0   1   0.0 0.0 78553.0, 78553.0 -1.44
BXD2/TyJ m 106983.0 0.0   1   0.0 0.0 106983.0, 106983.0 -0.23
BXD32/TyJ m 145324.0 0.0   1   0.0 0.0 145324.0, 145324.0 1.39
BXD33/TyJ m 138086.0 0.0   1   0.0 0.0 138086.0, 138086.0 1.09
BXD34/TyJ m 74926.0 0.0   1   0.0 0.0 74926.0, 74926.0 -1.59
BXD36/TyJ m 157502.0 0.0   1   0.0 0.0 157502.0, 157502.0 1.91
BXD38/TyJ m 109089.0 0.0   1   0.0 0.0 109089.0, 109089.0 -0.14
BXD39/TyJ m 92694.0 0.0   1   0.0 0.0 92694.0, 92694.0 -0.84
BXD40/TyJ m 124990.0 0.0   1   0.0 0.0 124990.0, 124990.0 0.53
BXD42/TyJ m 56698.0 0.0   1   0.0 0.0 56698.0, 56698.0 -2.36
BXD5/TyJ m 104761.0 0.0   1   0.0 0.0 104761.0, 104761.0 -0.33
BXD6/TyJ m 113422.0 0.0   1   0.0 0.0 113422.0, 113422.0 0.04
BXD8/TyJ m 112013.0 0.0   1   0.0 0.0 112013.0, 112013.0 -0.02
BXD9/TyJ m 110706.0 0.0   1   0.0 0.0 110706.0, 110706.0 -0.07
BXH10/TyJ m 102819.0 0.0   1   0.0 0.0 102819.0, 102819.0 -0.41
BXH19/TyJ m 89960.0 0.0   1   0.0 0.0 89960.0, 89960.0 -0.95
BXH20/KccJ m 134634.0 0.0   1   0.0 0.0 134634.0, 134634.0 0.94
BXH22/KccJ m 105368.0 0.0   1   0.0 0.0 105368.0, 105368.0 -0.3
BXH2/TyJ m 121985.0 0.0   1   0.0 0.0 121985.0, 121985.0 0.4
BXH4/TyJ m 102185.0 15216.0   2   10759.0 0.149 91426.0, 112945.0 -0.44
BXH6/TyJ m 170367.0 0.0   1   0.0 0.0 170367.0, 170367.0 2.45
BXH7/TyJ m 116710.0 0.0   1   0.0 0.0 116710.0, 116710.0 0.18
BXH8/TyJ m 138559.0 0.0   1   0.0 0.0 138559.0, 138559.0 1.11
BXH9/TyJ m 160467.0 0.0   1   0.0 0.0 160467.0, 160467.0 2.03
C3H/HeJ m 118318.0 8999.0   2   6363.0 0.0761 111955.0, 124681.0 0.25
C57BL/6J m 120438.0 16935.0   5 7574.0 0.141 101332.0, 145447.0 0.34
C57L/J m 160226.0 0.0   1   0.0 0.0 160226.0, 160226.0 2.02
C58/J m 126894.0 0.0   1   0.0 0.0 126894.0, 126894.0 0.61
CAST/EiJ m 115977.0 0.0   1   0.0 0.0 115977.0, 115977.0 0.15
CBA/J m 69805.0 0.0   1   0.0 0.0 69805.0, 69805.0 -1.81
CE/J m 103252.0 0.0   1   0.0 0.0 103252.0, 103252.0 -0.39
CXB11/HiAJ m 125595.0 27810.0   2   19664.0 0.221 105930.0, 145259.0 0.56
CXB12/HiAJ m 88223.0 2728.0   2   1929.0 0.0309 86294.0, 90152.0 -1.03
CXB13/HiAJ m 112177.0 20499.0   3 11835.0 0.183 88692.0, 126483.0 -0.01
CXB1/ByJ m 107262.0 7281.0   3 4204.0 0.0679 99501.0, 113943.0 -0.22
CXB2/ByJ m 110977.0 13468.0   3 7776.0 0.121 95426.0, 118890.0 -0.06
CXB3/ByJ m 128820.0 17431.0   2   12326.0 0.135 116494.0, 141146.0 0.69
CXB4/ByJ m 104928.0 15250.0   2   10783.0 0.145 94145.0, 115712.0 -0.32
CXB6/ByJ m 81785.0 7193.0   3 4153.0 0.0879 74040.0, 88255.0 -1.3
CXB7/ByJ m 85098.0 18942.0   2   13394.0 0.223 71704.0, 98493.0 -1.16
CXB8/HiAJ m 110597.0 20286.0   3 11712.0 0.183 91144.0, 131624.0 -0.08
CXB9/HiAJ m 122905.0 11832.0   3 6831.0 0.0963 110338.0, 133832.0 0.44
DBA/2J m 96474.0 21422.0   4 10711.0 0.222 72520.0, 124614.0 -0.68
FVB/NJ m 111744.0 0.0   1   0.0 0.0 111744.0, 111744.0 -0.03
I/LnJ m 125113.0 0.0   1   0.0 0.0 125113.0, 125113.0 0.54
KK/HlJ m 103753.0 0.0   1   0.0 0.0 103753.0, 103753.0 -0.37
LG/J m 113720.0 0.0   1   0.0 0.0 113720.0, 113720.0 0.05
LP/J m 152775.0 0.0   1   0.0 0.0 152775.0, 152775.0 1.71
MA/MyJ m 83546.0 0.0   1   0.0 0.0 83546.0, 83546.0 -1.22
NOD/ShiLtJ m 99418.0 0.0   1   0.0 0.0 99418.0, 99418.0 -0.55
NON/ShiLtJ m 112335.0 0.0   1   0.0 0.0 112335.0, 112335.0 -0.01
NZW/LacJ m 98269.0 0.0   1   0.0 0.0 98269.0, 98269.0 -0.6
PL/J m 103963.0 0.0   1   0.0 0.0 103963.0, 103963.0 -0.36
RIIIS/J m 154836.0 0.0   1   0.0 0.0 154836.0, 154836.0 1.79
SEA/GnJ m 70662.0 0.0   1   0.0 0.0 70662.0, 70662.0 -1.77
SJL/J m 106530.0 0.0   1   0.0 0.0 106530.0, 106530.0 -0.25
SM/J m 89484.0 0.0   1   0.0 0.0 89484.0, 89484.0 -0.97
SWR/J m 147121.0 0.0   1   0.0 0.0 147121.0, 147121.0 1.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 117047.5 12441.3364 142331.3376 91763.6624
AXB19b/PgnJ m 121973.6 12441.3364 147257.4376 96689.7624
AXB24/PgnJ m 123941.75 12441.3364 149225.5876 98657.9124
BALB/cJ m 111149.7667 10158.3086 131793.9336 90505.5997
BXA16/PgnJ m 127517.5 12441.3364 152801.3376 102233.6624
BXD19/TyJ m 98807.25 12441.3364 124091.0876 73523.4124
BXD28/TyJ m 103794.5 12441.3364 129078.3376 78510.6624
BXH4/TyJ m 102185.45 12441.3364 127469.2876 76901.6124
C3H/HeJ m 118318.2 12441.3364 143602.0376 93034.3624
C57BL/6J m 120438.2 7868.592 136429.103 104447.297
CXB11/HiAJ m 125594.95 12441.3364 150878.7876 100311.1124
CXB12/HiAJ m 88223.3 12441.3364 113507.1376 62939.4624
CXB13/HiAJ m 112176.5667 10158.3086 132820.7336 91532.3997
CXB1/ByJ m 107261.8333 10158.3086 127906.0003 86617.6664
CXB2/ByJ m 110976.8667 10158.3086 131621.0336 90332.6997
CXB3/ByJ m 128819.8 12441.3364 154103.6376 103535.9624
CXB4/ByJ m 104928.1 12441.3364 130211.9376 79644.2624
CXB6/ByJ m 81785.1 10158.3086 102429.267 61140.933
CXB7/ByJ m 85098.4 12441.3364 110382.2376 59814.5624
CXB8/HiAJ m 110596.8 10158.3086 131240.967 89952.633
CXB9/HiAJ m 122904.8333 10158.3086 143549.0003 102260.6664
DBA/2J m 96473.925 8797.3533 114352.298 78595.552




  GWAS USING LINEAR MIXED MODELS