Phenotype measure:   HMDPpheno7   threonate

ID, description, units MPD:50228   threonate   liver threonate (16h fast), relative abundance  
Data set, strains HMDPpheno7   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno7 - liver threonate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means136377   None
Median of the strain means135410   None
SD of the strain means± 44432
Coefficient of variation (CV)0.326
Min–max range of strain means33156   –   246556   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 64780130193.3873 3084768104.447 1.5635 0.1201
Residuals 34 67080473477.6825 1972955102.2848


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 82760.0 0.0   1   0.0 0.0 82760.0, 82760.0 -1.21
A/J m 140317.0 54459.0   2   38508.0 0.388 101809.0, 178826.0 0.09
AKR/J m 197538.0 0.0   1   0.0 0.0 197538.0, 197538.0 1.38
AXB10/PgnJ m 60905.0 0.0   1   0.0 0.0 60905.0, 60905.0 -1.7
AXB12/PgnJ m 103704.0 0.0   1   0.0 0.0 103704.0, 103704.0 -0.74
AXB13/PgnJ m 58252.0 0.0   1   0.0 0.0 58252.0, 58252.0 -1.76
AXB15/PgnJ m 152487.0 0.0   1   0.0 0.0 152487.0, 152487.0 0.36
AXB19a/PgnJ m 118783.0 0.0   1   0.0 0.0 118783.0, 118783.0 -0.4
AXB19b/PgnJ m 116156.0 12943.0   2   9152.0 0.111 107004.0, 125308.0 -0.46
AXB19/PgnJ m 83150.0 0.0   1   0.0 0.0 83150.0, 83150.0 -1.2
AXB1/PgnJ m 64294.0 0.0   1   0.0 0.0 64294.0, 64294.0 -1.62
AXB23/PgnJ m 91053.0 0.0   1   0.0 0.0 91053.0, 91053.0 -1.02
AXB24/PgnJ m 130426.0 4732.0   2   3346.0 0.0363 127080.0, 133772.0 -0.13
AXB2/PgnJ m 131908.0 0.0   1   0.0 0.0 131908.0, 131908.0 -0.1
AXB4/PgnJ m 118798.0 0.0   1   0.0 0.0 118798.0, 118798.0 -0.4
AXB5/PgnJ m 87318.0 0.0   1   0.0 0.0 87318.0, 87318.0 -1.1
AXB6/PgnJ m 59327.0 0.0   1   0.0 0.0 59327.0, 59327.0 -1.73
AXB8/PgnJ m 157169.0 0.0   1   0.0 0.0 157169.0, 157169.0 0.47
BALB/cJ m 194781.0 13963.0   3 8061.0 0.0717 180987.0, 208907.0 1.31
BTBR T+ Itpr3tf/J m 215334.0 0.0   1   0.0 0.0 215334.0, 215334.0 1.78
BUB/BnJ m 113065.0 0.0   1   0.0 0.0 113065.0, 113065.0 -0.52
BXA11/PgnJ m 166228.0 0.0   1   0.0 0.0 166228.0, 166228.0 0.67
BXA12/PgnJ m 103946.0 0.0   1   0.0 0.0 103946.0, 103946.0 -0.73
BXA13/PgnJ m 144070.0 0.0   1   0.0 0.0 144070.0, 144070.0 0.17
BXA14/PgnJ m 143961.0 0.0   1   0.0 0.0 143961.0, 143961.0 0.17
BXA16/PgnJ m 108828.0 7215.0   2   5101.0 0.0663 103726.0, 113929.0 -0.62
BXA1/PgnJ m 134055.0 0.0   1   0.0 0.0 134055.0, 134055.0 -0.05
BXA24/PgnJ m 126447.0 0.0   1   0.0 0.0 126447.0, 126447.0 -0.22
BXA25/PgnJ m 49062.0 0.0   1   0.0 0.0 49062.0, 49062.0 -1.97
BXA26/PgnJ m 75690.0 0.0   1   0.0 0.0 75690.0, 75690.0 -1.37
BXA2/PgnJ m 111026.0 0.0   1   0.0 0.0 111026.0, 111026.0 -0.57
BXA4/PgnJ m 204023.0 0.0   1   0.0 0.0 204023.0, 204023.0 1.52
BXA7/PgnJ m 102778.0 0.0   1   0.0 0.0 102778.0, 102778.0 -0.76
BXA8/PgnJ m 168159.0 0.0   1   0.0 0.0 168159.0, 168159.0 0.72
BXD11/TyJ m 165100.0 0.0   1   0.0 0.0 165100.0, 165100.0 0.65
BXD12/TyJ m 120005.0 0.0   1   0.0 0.0 120005.0, 120005.0 -0.37
BXD13/TyJ m 67144.0 0.0   1   0.0 0.0 67144.0, 67144.0 -1.56
BXD14/TyJ m 162363.0 0.0   1   0.0 0.0 162363.0, 162363.0 0.58
BXD15/TyJ m 153579.0 0.0   1   0.0 0.0 153579.0, 153579.0 0.39
BXD18/TyJ m 130046.0 0.0   1   0.0 0.0 130046.0, 130046.0 -0.14
BXD19/TyJ m 124335.0 7226.0   2   5110.0 0.0581 119225.0, 129445.0 -0.27
BXD1/TyJ m 175923.0 0.0   1   0.0 0.0 175923.0, 175923.0 0.89
BXD20/TyJ m 188820.0 0.0   1   0.0 0.0 188820.0, 188820.0 1.18
BXD21/TyJ m 160151.0 0.0   1   0.0 0.0 160151.0, 160151.0 0.54
BXD22/TyJ m 169740.0 0.0   1   0.0 0.0 169740.0, 169740.0 0.75
BXD24/TyJ m 215806.0 0.0   1   0.0 0.0 215806.0, 215806.0 1.79
BXD24/TyJ-Cep290rd16/J m 124546.0 0.0   1   0.0 0.0 124546.0, 124546.0 -0.27
BXD28/TyJ m 131386.0 6007.0   2   4248.0 0.0457 127138.0, 135634.0 -0.11
BXD29-Tlr4lps-2J/J m 142563.0 0.0   1   0.0 0.0 142563.0, 142563.0 0.14
BXD2/TyJ m 114490.0 0.0   1   0.0 0.0 114490.0, 114490.0 -0.49
BXD32/TyJ m 91022.0 0.0   1   0.0 0.0 91022.0, 91022.0 -1.02
BXD33/TyJ m 181556.0 0.0   1   0.0 0.0 181556.0, 181556.0 1.02
BXD34/TyJ m 109803.0 0.0   1   0.0 0.0 109803.0, 109803.0 -0.6
BXD36/TyJ m 153827.0 0.0   1   0.0 0.0 153827.0, 153827.0 0.39
BXD38/TyJ m 155170.0 0.0   1   0.0 0.0 155170.0, 155170.0 0.42
BXD39/TyJ m 221580.0 0.0   1   0.0 0.0 221580.0, 221580.0 1.92
BXD40/TyJ m 118628.0 0.0   1   0.0 0.0 118628.0, 118628.0 -0.4
BXD42/TyJ m 182714.0 0.0   1   0.0 0.0 182714.0, 182714.0 1.04
BXD5/TyJ m 143839.0 0.0   1   0.0 0.0 143839.0, 143839.0 0.17
BXD6/TyJ m 181994.0 0.0   1   0.0 0.0 181994.0, 181994.0 1.03
BXD8/TyJ m 236130.0 0.0   1   0.0 0.0 236130.0, 236130.0 2.25
BXD9/TyJ m 110735.0 0.0   1   0.0 0.0 110735.0, 110735.0 -0.58
BXH10/TyJ m 70939.0 0.0   1   0.0 0.0 70939.0, 70939.0 -1.47
BXH19/TyJ m 33156.0 0.0   1   0.0 0.0 33156.0, 33156.0 -2.32
BXH20/KccJ m 162201.0 0.0   1   0.0 0.0 162201.0, 162201.0 0.58
BXH22/KccJ m 97148.0 0.0   1   0.0 0.0 97148.0, 97148.0 -0.88
BXH2/TyJ m 99679.0 0.0   1   0.0 0.0 99679.0, 99679.0 -0.83
BXH4/TyJ m 153261.0 20735.0   2   14662.0 0.135 138600.0, 167923.0 0.38
BXH6/TyJ m 106824.0 0.0   1   0.0 0.0 106824.0, 106824.0 -0.67
BXH7/TyJ m 148885.0 0.0   1   0.0 0.0 148885.0, 148885.0 0.28
BXH8/TyJ m 116412.0 0.0   1   0.0 0.0 116412.0, 116412.0 -0.45
BXH9/TyJ m 178328.0 0.0   1   0.0 0.0 178328.0, 178328.0 0.94
C3H/HeJ m 156576.0 129779.0   2   91767.0 0.829 64808.0, 248344.0 0.45
C57BL/6J m 116074.0 24955.0   5 11160.0 0.215 94913.0, 154315.0 -0.46
C57L/J m 56954.0 0.0   1   0.0 0.0 56954.0, 56954.0 -1.79
C58/J m 88048.0 0.0   1   0.0 0.0 88048.0, 88048.0 -1.09
CAST/EiJ m 126207.0 0.0   1   0.0 0.0 126207.0, 126207.0 -0.23
CBA/J m 115160.0 0.0   1   0.0 0.0 115160.0, 115160.0 -0.48
CE/J m 189230.0 0.0   1   0.0 0.0 189230.0, 189230.0 1.19
CXB11/HiAJ m 168996.0 57191.0   2   40440.0 0.338 128555.0, 209436.0 0.73
CXB12/HiAJ m 139313.0 7429.0   2   5253.0 0.0533 134060.0, 144566.0 0.07
CXB13/HiAJ m 148807.0 59056.0   3 34096.0 0.397 82827.0, 196716.0 0.28
CXB1/ByJ m 144334.0 25568.0   3 14762.0 0.177 122868.0, 172621.0 0.18
CXB2/ByJ m 149963.0 51375.0   3 29661.0 0.343 102321.0, 204395.0 0.31
CXB3/ByJ m 116794.0 11805.0   2   8347.0 0.101 108447.0, 125142.0 -0.44
CXB4/ByJ m 139334.0 10901.0   2   7708.0 0.0782 131625.0, 147042.0 0.07
CXB6/ByJ m 138351.0 4865.0   3 2809.0 0.0352 133041.0, 142592.0 0.04
CXB7/ByJ m 151592.0 26804.0   2   18953.0 0.177 132639.0, 170546.0 0.34
CXB8/HiAJ m 136764.0 24777.0   3 14305.0 0.181 119320.0, 165125.0 0.01
CXB9/HiAJ m 117499.0 19722.0   3 11386.0 0.168 102117.0, 139733.0 -0.42
DBA/2J m 246556.0 88908.0   4 44454.0 0.361 174075.0, 369247.0 2.48
FVB/NJ m 121058.0 0.0   1   0.0 0.0 121058.0, 121058.0 -0.34
I/LnJ m 173726.0 0.0   1   0.0 0.0 173726.0, 173726.0 0.84
KK/HlJ m 150617.0 0.0   1   0.0 0.0 150617.0, 150617.0 0.32
LG/J m 213567.0 0.0   1   0.0 0.0 213567.0, 213567.0 1.74
LP/J m 211734.0 0.0   1   0.0 0.0 211734.0, 211734.0 1.7
MA/MyJ m 124371.0 0.0   1   0.0 0.0 124371.0, 124371.0 -0.27
NOD/ShiLtJ m 65524.0 0.0   1   0.0 0.0 65524.0, 65524.0 -1.59
NON/ShiLtJ m 149548.0 0.0   1   0.0 0.0 149548.0, 149548.0 0.3
NZW/LacJ m 102348.0 0.0   1   0.0 0.0 102348.0, 102348.0 -0.77
PL/J m 147644.0 0.0   1   0.0 0.0 147644.0, 147644.0 0.25
RIIIS/J m 240475.0 0.0   1   0.0 0.0 240475.0, 240475.0 2.34
SEA/GnJ m 111963.0 0.0   1   0.0 0.0 111963.0, 111963.0 -0.55
SJL/J m 214218.0 0.0   1   0.0 0.0 214218.0, 214218.0 1.75
SM/J m 112387.0 0.0   1   0.0 0.0 112387.0, 112387.0 -0.54
SWR/J m 154622.0 0.0   1   0.0 0.0 154622.0, 154622.0 0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 140317.25 31408.2402 204146.4737 76488.0263
AXB19b/PgnJ m 116155.75 31408.2402 179984.9737 52326.5263
AXB24/PgnJ m 130426.05 31408.2402 194255.2737 66596.8263
BALB/cJ m 194780.8667 25644.7207 246897.2095 142664.5238
BXA16/PgnJ m 108827.75 31408.2402 172656.9737 44998.5263
BXD19/TyJ m 124335.1 31408.2402 188164.3237 60505.8763
BXD28/TyJ m 131385.65 31408.2402 195214.8737 67556.4263
BXH4/TyJ m 153261.35 31408.2402 217090.5737 89432.1263
C3H/HeJ m 156576.0 31408.2402 220405.2237 92746.7763
C57BL/6J m 116074.0 19864.3153 156443.1456 75704.8544
CXB11/HiAJ m 168995.8 31408.2402 232825.0237 105166.5763
CXB12/HiAJ m 139313.0 31408.2402 203142.2237 75483.7763
CXB13/HiAJ m 148807.2667 25644.7207 200923.6095 96690.9238
CXB1/ByJ m 144333.5667 25644.7207 196449.9095 92217.2238
CXB2/ByJ m 149963.3333 25644.7207 202079.6762 97846.9905
CXB3/ByJ m 116794.5 31408.2402 180623.7237 52965.2763
CXB4/ByJ m 139333.75 31408.2402 203162.9737 75504.5263
CXB6/ByJ m 138351.2333 25644.7207 190467.5762 86234.8905
CXB7/ByJ m 151592.4 31408.2402 215421.6237 87763.1763
CXB8/HiAJ m 136764.2 25644.7207 188880.5429 84647.8571
CXB9/HiAJ m 117499.3667 25644.7207 169615.7095 65383.0238
DBA/2J m 246556.275 22208.9796 291690.3519 201422.1981




  GWAS USING LINEAR MIXED MODELS