Phenotype measure:   HMDPpheno7   glucarate

ID, description, units MPD:50226   glucarate   liver glucarate (saccharate) (16h fast), relative abundance  
Data set, strains HMDPpheno7   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno7 - liver glucarate (saccharate) (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means229112   None
Median of the strain means161686   None
SD of the strain means± 229625
Coefficient of variation (CV)1.00
Min–max range of strain means47134   –   1479713   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 400634557194.931 19077836056.9015 3.5755 0.0005
Residuals 34 181412424474.718 5335659543.3741


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 101895.0 0.0   1   0.0 0.0 101895.0, 101895.0 -0.55
A/J m 80354.0 5810.0   2   4108.0 0.0723 76246.0, 84462.0 -0.65
AKR/J m 152718.0 0.0   1   0.0 0.0 152718.0, 152718.0 -0.33
AXB10/PgnJ m 139794.0 0.0   1   0.0 0.0 139794.0, 139794.0 -0.39
AXB12/PgnJ m 348157.0 0.0   1   0.0 0.0 348157.0, 348157.0 0.52
AXB13/PgnJ m 238493.0 0.0   1   0.0 0.0 238493.0, 238493.0 0.04
AXB15/PgnJ m 331266.0 0.0   1   0.0 0.0 331266.0, 331266.0 0.44
AXB19a/PgnJ m 132777.0 0.0   1   0.0 0.0 132777.0, 132777.0 -0.42
AXB19b/PgnJ m 317930.0 78545.0   2   55540.0 0.247 262390.0, 373470.0 0.39
AXB19/PgnJ m 292587.0 0.0   1   0.0 0.0 292587.0, 292587.0 0.28
AXB1/PgnJ m 167840.0 0.0   1   0.0 0.0 167840.0, 167840.0 -0.27
AXB23/PgnJ m 80572.0 0.0   1   0.0 0.0 80572.0, 80572.0 -0.65
AXB24/PgnJ m 233222.0 36733.0   2   25974.0 0.158 207247.0, 259196.0 0.02
AXB2/PgnJ m 93530.0 0.0   1   0.0 0.0 93530.0, 93530.0 -0.59
AXB4/PgnJ m 253811.0 0.0   1   0.0 0.0 253811.0, 253811.0 0.11
AXB5/PgnJ m 47134.0 0.0   1   0.0 0.0 47134.0, 47134.0 -0.79
AXB6/PgnJ m 89954.0 0.0   1   0.0 0.0 89954.0, 89954.0 -0.61
AXB8/PgnJ m 189773.0 0.0   1   0.0 0.0 189773.0, 189773.0 -0.17
BALB/cJ m 132255.0 26866.0   3 15511.0 0.203 108882.0, 161607.0 -0.42
BTBR T+ Itpr3tf/J m 71607.0 0.0   1   0.0 0.0 71607.0, 71607.0 -0.69
BUB/BnJ m 100624.0 0.0   1   0.0 0.0 100624.0, 100624.0 -0.56
BXA11/PgnJ m 485178.0 0.0   1   0.0 0.0 485178.0, 485178.0 1.12
BXA12/PgnJ m 88916.0 0.0   1   0.0 0.0 88916.0, 88916.0 -0.61
BXA13/PgnJ m 203428.0 0.0   1   0.0 0.0 203428.0, 203428.0 -0.11
BXA14/PgnJ m 310166.0 0.0   1   0.0 0.0 310166.0, 310166.0 0.35
BXA16/PgnJ m 229627.0 40324.0   2   28513.0 0.176 201114.0, 258141.0 0.0
BXA1/PgnJ m 103966.0 0.0   1   0.0 0.0 103966.0, 103966.0 -0.55
BXA24/PgnJ m 197072.0 0.0   1   0.0 0.0 197072.0, 197072.0 -0.14
BXA25/PgnJ m 66067.0 0.0   1   0.0 0.0 66067.0, 66067.0 -0.71
BXA26/PgnJ m 96903.0 0.0   1   0.0 0.0 96903.0, 96903.0 -0.58
BXA2/PgnJ m 271750.0 0.0   1   0.0 0.0 271750.0, 271750.0 0.19
BXA4/PgnJ m 195399.0 0.0   1   0.0 0.0 195399.0, 195399.0 -0.15
BXA7/PgnJ m 211110.0 0.0   1   0.0 0.0 211110.0, 211110.0 -0.08
BXA8/PgnJ m 223284.0 0.0   1   0.0 0.0 223284.0, 223284.0 -0.03
BXD11/TyJ m 610177.0 0.0   1   0.0 0.0 610177.0, 610177.0 1.66
BXD12/TyJ m 171610.0 0.0   1   0.0 0.0 171610.0, 171610.0 -0.25
BXD13/TyJ m 269881.0 0.0   1   0.0 0.0 269881.0, 269881.0 0.18
BXD14/TyJ m 100559.0 0.0   1   0.0 0.0 100559.0, 100559.0 -0.56
BXD15/TyJ m 139178.0 0.0   1   0.0 0.0 139178.0, 139178.0 -0.39
BXD18/TyJ m 167194.0 0.0   1   0.0 0.0 167194.0, 167194.0 -0.27
BXD19/TyJ m 225859.0 238455.0   2   168613.0 1.06 57246.0, 394472.0 -0.01
BXD1/TyJ m 491255.0 0.0   1   0.0 0.0 491255.0, 491255.0 1.14
BXD20/TyJ m 1068604.0 0.0   1   0.0 0.0 1068604.0, 1068604.0 3.66
BXD21/TyJ m 281245.0 0.0   1   0.0 0.0 281245.0, 281245.0 0.23
BXD22/TyJ m 111201.0 0.0   1   0.0 0.0 111201.0, 111201.0 -0.51
BXD24/TyJ m 631060.0 0.0   1   0.0 0.0 631060.0, 631060.0 1.75
BXD24/TyJ-Cep290rd16/J m 448834.0 0.0   1   0.0 0.0 448834.0, 448834.0 0.96
BXD28/TyJ m 81366.0 20189.0   2   14276.0 0.248 67090.0, 95642.0 -0.64
BXD29-Tlr4lps-2J/J m 232215.0 0.0   1   0.0 0.0 232215.0, 232215.0 0.01
BXD2/TyJ m 252033.0 0.0   1   0.0 0.0 252033.0, 252033.0 0.1
BXD32/TyJ m 214656.0 0.0   1   0.0 0.0 214656.0, 214656.0 -0.06
BXD33/TyJ m 279801.0 0.0   1   0.0 0.0 279801.0, 279801.0 0.22
BXD34/TyJ m 172501.0 0.0   1   0.0 0.0 172501.0, 172501.0 -0.25
BXD36/TyJ m 67566.0 0.0   1   0.0 0.0 67566.0, 67566.0 -0.7
BXD38/TyJ m 1479713.0 0.0   1   0.0 0.0 1479713.0, 1479713.0 5.45
BXD39/TyJ m 873956.0 0.0   1   0.0 0.0 873956.0, 873956.0 2.81
BXD40/TyJ m 127188.0 0.0   1   0.0 0.0 127188.0, 127188.0 -0.44
BXD42/TyJ m 1056887.0 0.0   1   0.0 0.0 1056887.0, 1056887.0 3.6
BXD5/TyJ m 150068.0 0.0   1   0.0 0.0 150068.0, 150068.0 -0.34
BXD6/TyJ m 323199.0 0.0   1   0.0 0.0 323199.0, 323199.0 0.41
BXD8/TyJ m 969239.0 0.0   1   0.0 0.0 969239.0, 969239.0 3.22
BXD9/TyJ m 86695.0 0.0   1   0.0 0.0 86695.0, 86695.0 -0.62
BXH10/TyJ m 159600.0 0.0   1   0.0 0.0 159600.0, 159600.0 -0.3
BXH19/TyJ m 143934.0 0.0   1   0.0 0.0 143934.0, 143934.0 -0.37
BXH20/KccJ m 112978.0 0.0   1   0.0 0.0 112978.0, 112978.0 -0.51
BXH22/KccJ m 246203.0 0.0   1   0.0 0.0 246203.0, 246203.0 0.07
BXH2/TyJ m 92695.0 0.0   1   0.0 0.0 92695.0, 92695.0 -0.59
BXH4/TyJ m 84482.0 3639.0   2   2573.0 0.0431 81910.0, 87055.0 -0.63
BXH6/TyJ m 93592.0 0.0   1   0.0 0.0 93592.0, 93592.0 -0.59
BXH7/TyJ m 212940.0 0.0   1   0.0 0.0 212940.0, 212940.0 -0.07
BXH8/TyJ m 179954.0 0.0   1   0.0 0.0 179954.0, 179954.0 -0.21
BXH9/TyJ m 84385.0 0.0   1   0.0 0.0 84385.0, 84385.0 -0.63
C3H/HeJ m 78865.0 9843.0   2   6960.0 0.125 71905.0, 85825.0 -0.65
C57BL/6J m 306046.0 114999.0   5 51429.0 0.376 177836.0, 458915.0 0.34
C57L/J m 250246.0 0.0   1   0.0 0.0 250246.0, 250246.0 0.09
C58/J m 78234.0 0.0   1   0.0 0.0 78234.0, 78234.0 -0.66
CAST/EiJ m 73536.0 0.0   1   0.0 0.0 73536.0, 73536.0 -0.68
CBA/J m 61315.0 0.0   1   0.0 0.0 61315.0, 61315.0 -0.73
CE/J m 114490.0 0.0   1   0.0 0.0 114490.0, 114490.0 -0.5
CXB11/HiAJ m 86343.0 40253.0   2   28463.0 0.466 57879.0, 114806.0 -0.62
CXB12/HiAJ m 119088.0 10260.0   2   7255.0 0.0862 111834.0, 126344.0 -0.48
CXB13/HiAJ m 284931.0 96443.0   3 55681.0 0.338 175677.0, 358240.0 0.24
CXB1/ByJ m 215629.0 38716.0   3 22353.0 0.18 172257.0, 246701.0 -0.06
CXB2/ByJ m 303693.0 51258.0   3 29594.0 0.169 255563.0, 357591.0 0.32
CXB3/ByJ m 154802.0 17180.0   2   12148.0 0.111 142654.0, 166950.0 -0.32
CXB4/ByJ m 145428.0 6191.0   2   4378.0 0.0426 141050.0, 149805.0 -0.36
CXB6/ByJ m 122205.0 20099.0   3 11604.0 0.164 102520.0, 142694.0 -0.47
CXB7/ByJ m 356487.0 34707.0   2   24542.0 0.0974 331945.0, 381029.0 0.55
CXB8/HiAJ m 259426.0 71790.0   3 41448.0 0.277 214841.0, 342241.0 0.13
CXB9/HiAJ m 217629.0 58507.0   3 33779.0 0.269 153510.0, 268118.0 -0.05
DBA/2J m 229615.0 64373.0   4 32186.0 0.28 182565.0, 324555.0 0.0
FVB/NJ m 58681.0 0.0   1   0.0 0.0 58681.0, 58681.0 -0.74
I/LnJ m 252578.0 0.0   1   0.0 0.0 252578.0, 252578.0 0.1
KK/HlJ m 163773.0 0.0   1   0.0 0.0 163773.0, 163773.0 -0.28
LG/J m 69821.0 0.0   1   0.0 0.0 69821.0, 69821.0 -0.69
LP/J m 100096.0 0.0   1   0.0 0.0 100096.0, 100096.0 -0.56
MA/MyJ m 83909.0 0.0   1   0.0 0.0 83909.0, 83909.0 -0.63
NOD/ShiLtJ m 91169.0 0.0   1   0.0 0.0 91169.0, 91169.0 -0.6
NON/ShiLtJ m 78836.0 0.0   1   0.0 0.0 78836.0, 78836.0 -0.65
NZW/LacJ m 85295.0 0.0   1   0.0 0.0 85295.0, 85295.0 -0.63
PL/J m 80248.0 0.0   1   0.0 0.0 80248.0, 80248.0 -0.65
RIIIS/J m 159496.0 0.0   1   0.0 0.0 159496.0, 159496.0 -0.3
SEA/GnJ m 72876.0 0.0   1   0.0 0.0 72876.0, 72876.0 -0.68
SJL/J m 73369.0 0.0   1   0.0 0.0 73369.0, 73369.0 -0.68
SM/J m 533238.0 0.0   1   0.0 0.0 533238.0, 533238.0 1.32
SWR/J m 150839.0 0.0   1   0.0 0.0 150839.0, 150839.0 -0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 80353.85 51651.0384 185321.3893 0.0
AXB19b/PgnJ m 317930.15 51651.0384 422897.6893 212962.6107
AXB24/PgnJ m 233221.7 51651.0384 338189.2393 128254.1607
BALB/cJ m 132254.7 42172.8963 217960.3369 46549.0631
BXA16/PgnJ m 229627.15 51651.0384 334594.6893 124659.6107
BXD19/TyJ m 225859.0 51651.0384 330826.5393 120891.4607
BXD28/TyJ m 81366.1 51651.0384 186333.6393 0.0
BXH4/TyJ m 84482.45 51651.0384 189449.9893 0.0
C3H/HeJ m 78865.15 51651.0384 183832.6893 0.0
C57BL/6J m 306046.46 32666.985 372433.7609 239659.1591
CXB11/HiAJ m 86342.6 51651.0384 191310.1393 0.0
CXB12/HiAJ m 119088.5 51651.0384 224056.0393 14120.9607
CXB13/HiAJ m 284930.7333 42172.8963 370636.3703 199225.0964
CXB1/ByJ m 215628.9667 42172.8963 301334.6036 129923.3297
CXB2/ByJ m 303692.6333 42172.8963 389398.2703 217986.9964
CXB3/ByJ m 154801.6 51651.0384 259769.1393 49834.0607
CXB4/ByJ m 145427.5 51651.0384 250395.0393 40459.9607
CXB6/ByJ m 122204.9667 42172.8963 207910.6036 36499.3297
CXB7/ByJ m 356486.8 51651.0384 461454.3393 251519.2607
CXB8/HiAJ m 259426.5 42172.8963 345132.1369 173720.8631
CXB9/HiAJ m 217629.0333 42172.8963 303334.6703 131923.3964
DBA/2J m 229614.925 36522.7995 303838.1838 155391.6662




  GWAS USING LINEAR MIXED MODELS