Project measure / variable:   HMDPpheno7   ascorbate

ID, description, units MPD:50225   ascorbate   liver ascorbate (Vitamin C) (16h fast), relative abundance    
Data set, strains HMDPpheno7   HMDP   94 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno7 - liver ascorbate (Vitamin C) (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested94 strains
Mean of the strain means1217181   None
Median of the strain means960345   None
SD of the strain means± 1124135
Coefficient of variation (CV)0.924
Min–max range of strain means5622   –   7035027   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 17 19468404473464.5 1145200263144.97 0.7987 0.6809
Residuals 28 40145205096174.8 1433757324863.39


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J m 191281.0 0.0   1   0.0 0.0 191281.0, 191281.0 -0.91
AXB12/PgnJ m 307652.0 0.0   1   0.0 0.0 307652.0, 307652.0 -0.81
AXB13/PgnJ m 960725.0 0.0   1   0.0 0.0 960725.0, 960725.0 -0.23
AXB15/PgnJ m 447380.0 0.0   1   0.0 0.0 447380.0, 447380.0 -0.68
AXB19a/PgnJ m 901489.0 0.0   1   0.0 0.0 901489.0, 901489.0 -0.28
AXB19b/PgnJ m 2243586.0 520902.0   2   368333.0 0.232 1875252.0, 2611919.0 0.91
AXB19/PgnJ m 1145439.0 0.0   1   0.0 0.0 1145439.0, 1145439.0 -0.06
AXB1/PgnJ m 891837.0 0.0   1   0.0 0.0 891837.0, 891837.0 -0.29
AXB23/PgnJ m 764946.0 0.0   1   0.0 0.0 764946.0, 764946.0 -0.4
AXB24/PgnJ m 1254893.0 490607.0   2   346912.0 0.391 907981.0, 1601804.0 0.03
AXB2/PgnJ m 274452.0 0.0   1   0.0 0.0 274452.0, 274452.0 -0.84
AXB4/PgnJ m 392616.0 0.0   1   0.0 0.0 392616.0, 392616.0 -0.73
AXB5/PgnJ m 793799.0 0.0   1   0.0 0.0 793799.0, 793799.0 -0.38
AXB6/PgnJ m 1577626.0 0.0   1   0.0 0.0 1577626.0, 1577626.0 0.32
AXB8/PgnJ m 843260.0 0.0   1   0.0 0.0 843260.0, 843260.0 -0.33
BALB/cJ m 598838.0 316087.0   3 182493.0 0.528 257991.0, 882304.0 -0.55
BUB/BnJ m 906329.0 0.0   1   0.0 0.0 906329.0, 906329.0 -0.28
BXA11/PgnJ m 229543.0 0.0   1   0.0 0.0 229543.0, 229543.0 -0.88
BXA13/PgnJ m 1476922.0 0.0   1   0.0 0.0 1476922.0, 1476922.0 0.23
BXA14/PgnJ m 1913823.0 0.0   1   0.0 0.0 1913823.0, 1913823.0 0.62
BXA16/PgnJ m 135713.0 0.0   1   0.0 0.0 135713.0, 135713.0 -0.96
BXA1/PgnJ m 933527.0 0.0   1   0.0 0.0 933527.0, 933527.0 -0.25
BXA24/PgnJ m 969953.0 0.0   1   0.0 0.0 969953.0, 969953.0 -0.22
BXA26/PgnJ m 2038505.0 0.0   1   0.0 0.0 2038505.0, 2038505.0 0.73
BXA2/PgnJ m 681419.0 0.0   1   0.0 0.0 681419.0, 681419.0 -0.48
BXA7/PgnJ m 1204143.0 0.0   1   0.0 0.0 1204143.0, 1204143.0 -0.01
BXA8/PgnJ m 1349439.0 0.0   1   0.0 0.0 1349439.0, 1349439.0 0.12
BXD12/TyJ m 4286149.0 0.0   1   0.0 0.0 4286149.0, 4286149.0 2.73
BXD14/TyJ m 4358433.0 0.0   1   0.0 0.0 4358433.0, 4358433.0 2.79
BXD15/TyJ m 133066.0 0.0   1   0.0 0.0 133066.0, 133066.0 -0.96
BXD18/TyJ m 535550.0 0.0   1   0.0 0.0 535550.0, 535550.0 -0.61
BXD19/TyJ m 1724019.0 1117924.0   2   790491.0 0.648 933527.0, 2514510.0 0.45
BXD1/TyJ m 7035027.0 0.0   1   0.0 0.0 7035027.0, 7035027.0 5.18
BXD20/TyJ m 2215277.0 0.0   1   0.0 0.0 2215277.0, 2215277.0 0.89
BXD21/TyJ m 1076184.0 0.0   1   0.0 0.0 1076184.0, 1076184.0 -0.13
BXD22/TyJ m 1530481.0 0.0   1   0.0 0.0 1530481.0, 1530481.0 0.28
BXD24/TyJ m 546298.0 0.0   1   0.0 0.0 546298.0, 546298.0 -0.6
BXD24/TyJ-Cep290rd16/J m 20209.0 0.0   1   0.0 0.0 20209.0, 20209.0 -1.06
BXD28/TyJ m 566849.0 414864.0   2   293353.0 0.732 273496.0, 860202.0 -0.58
BXD29-Tlr4lps-2J/J m 3936956.0 0.0   1   0.0 0.0 3936956.0, 3936956.0 2.42
BXD2/TyJ m 359424.0 0.0   1   0.0 0.0 359424.0, 359424.0 -0.76
BXD32/TyJ m 126644.0 0.0   1   0.0 0.0 126644.0, 126644.0 -0.97
BXD33/TyJ m 1770676.0 0.0   1   0.0 0.0 1770676.0, 1770676.0 0.49
BXD34/TyJ m 817461.0 0.0   1   0.0 0.0 817461.0, 817461.0 -0.36
BXD36/TyJ m 29743.0 0.0   1   0.0 0.0 29743.0, 29743.0 -1.06
BXD38/TyJ m 970343.0 0.0   1   0.0 0.0 970343.0, 970343.0 -0.22
BXD39/TyJ m 3328574.0 0.0   1   0.0 0.0 3328574.0, 3328574.0 1.88
BXD40/TyJ m 881987.0 0.0   1   0.0 0.0 881987.0, 881987.0 -0.3
BXD42/TyJ m 3508805.0 0.0   1   0.0 0.0 3508805.0, 3508805.0 2.04
BXD5/TyJ m 2831271.0 0.0   1   0.0 0.0 2831271.0, 2831271.0 1.44
BXD6/TyJ m 1137385.0 0.0   1   0.0 0.0 1137385.0, 1137385.0 -0.07
BXD8/TyJ m 515264.0 0.0   1   0.0 0.0 515264.0, 515264.0 -0.62
BXD9/TyJ m 933527.0 0.0   1   0.0 0.0 933527.0, 933527.0 -0.25
BXH10/TyJ m 2229966.0 0.0   1   0.0 0.0 2229966.0, 2229966.0 0.9
BXH20/KccJ m 479838.0 0.0   1   0.0 0.0 479838.0, 479838.0 -0.66
BXH22/KccJ m 1463150.0 0.0   1   0.0 0.0 1463150.0, 1463150.0 0.22
BXH2/TyJ m 515436.0 0.0   1   0.0 0.0 515436.0, 515436.0 -0.62
BXH4/TyJ m 2081494.0 1532070.0   2   1083337.0 0.736 998157.0, 3164831.0 0.77
BXH6/TyJ m 297576.0 0.0   1   0.0 0.0 297576.0, 297576.0 -0.82
BXH7/TyJ m 1501583.0 0.0   1   0.0 0.0 1501583.0, 1501583.0 0.25
BXH8/TyJ m 193084.0 0.0   1   0.0 0.0 193084.0, 193084.0 -0.91
BXH9/TyJ m 5622.0 0.0   1   0.0 0.0 5622.0, 5622.0 -1.08
C3H/HeJ m 349177.0 155434.0   2   109908.0 0.445 239269.0, 459086.0 -0.77
C57BL/6J m 1159199.0 1268136.0   5 567127.0 1.09 116852.0, 3131253.0 -0.05
C58/J m 1095285.0 0.0   1   0.0 0.0 1095285.0, 1095285.0 -0.11
CAST/EiJ m 2455832.0 0.0   1   0.0 0.0 2455832.0, 2455832.0 1.1
CBA/J m 1667892.0 0.0   1   0.0 0.0 1667892.0, 1667892.0 0.4
CE/J m 44321.0 0.0   1   0.0 0.0 44321.0, 44321.0 -1.04
CXB11/HiAJ m 1509035.0 422193.0   2   298536.0 0.28 1210499.0, 1807570.0 0.26
CXB12/HiAJ m 933527.0 0.0   1   0.0 0.0 933527.0, 933527.0 -0.25
CXB13/HiAJ m 1634826.0 584668.0   2   413423.0 0.358 1221404.0, 2048249.0 0.37
CXB1/ByJ m 1143909.0 992451.0   3 572992.0 0.868 431903.0, 2277565.0 -0.07
CXB2/ByJ m 515379.0 568813.0   2   402211.0 1.1 113168.0, 917591.0 -0.62
CXB3/ByJ m 53376.0 38671.0   2   27344.0 0.724 26032.0, 80720.0 -1.04
CXB4/ByJ m 683696.0 0.0   1   0.0 0.0 683696.0, 683696.0 -0.47
CXB6/ByJ m 1630627.0 758858.0   3 438127.0 0.465 892471.0, 2408617.0 0.37
CXB7/ByJ m 1468112.0 272797.0   2   192897.0 0.186 1275215.0, 1661009.0 0.22
CXB8/HiAJ m 2720299.0 3172232.0   3 1831489.0 1.17 343292.0, 6322396.0 1.34
CXB9/HiAJ m 1227985.0 481724.0   3 278123.0 0.392 929485.0, 1783722.0 0.01
DBA/2J m 1657680.0 1235043.0   4 617522.0 0.745 593832.0, 3415081.0 0.39
FVB/NJ m 18500.0 0.0   1   0.0 0.0 18500.0, 18500.0 -1.07
I/LnJ m 959965.0 0.0   1   0.0 0.0 959965.0, 959965.0 -0.23
KK/HlJ m 2333956.0 0.0   1   0.0 0.0 2333956.0, 2333956.0 0.99
LG/J m 58800.0 0.0   1   0.0 0.0 58800.0, 58800.0 -1.03
MA/MyJ m 536995.0 0.0   1   0.0 0.0 536995.0, 536995.0 -0.61
NOD/ShiLtJ m 104042.0 0.0   1   0.0 0.0 104042.0, 104042.0 -0.99
NON/ShiLtJ m 106457.0 0.0   1   0.0 0.0 106457.0, 106457.0 -0.99
NZW/LacJ m 1102068.0 0.0   1   0.0 0.0 1102068.0, 1102068.0 -0.1
PL/J m 1077542.0 0.0   1   0.0 0.0 1077542.0, 1077542.0 -0.12
RIIIS/J m 899566.0 0.0   1   0.0 0.0 899566.0, 899566.0 -0.28
SEA/GnJ m 1857495.0 0.0   1   0.0 0.0 1857495.0, 1857495.0 0.57
SJL/J m 1023648.0 0.0   1   0.0 0.0 1023648.0, 1023648.0 -0.17
SM/J m 2326661.0 0.0   1   0.0 0.0 2326661.0, 2326661.0 0.99
SWR/J m 686649.0 0.0   1   0.0 0.0 686649.0, 686649.0 -0.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
AXB19b/PgnJ m 2243585.65 846686.8739 3977945.0894 509226.2106
AXB24/PgnJ m 1254892.65 846686.8739 2989252.0894 0.0
BALB/cJ m 598837.9667 691316.9377 2014936.519 0.0
BXD19/TyJ m 1724018.6 846686.8739 3458378.0394 0.0
BXD28/TyJ m 566848.8 846686.8739 2301208.2394 0.0
BXH4/TyJ m 2081493.8 846686.8739 3815853.2394 347134.3606
C3H/HeJ m 349177.35 846686.8739 2083536.7894 0.0
C57BL/6J m 1159198.82 535491.7973 2256104.042 62293.598
CXB11/HiAJ m 1509034.75 846686.8739 3243394.1894 0.0
CXB13/HiAJ m 1634826.05 846686.8739 3369185.4894 0.0
CXB1/ByJ m 1143908.7333 691316.9377 2560007.2857 0.0
CXB2/ByJ m 515379.3 846686.8739 2249738.7394 0.0
CXB3/ByJ m 53375.9 846686.8739 1787735.3394 0.0
CXB6/ByJ m 1630626.9 691316.9377 3046725.4523 214528.3477
CXB7/ByJ m 1468112.0 846686.8739 3202471.4394 0.0
CXB8/HiAJ m 2720298.9333 691316.9377 4136397.4857 1304200.381
CXB9/HiAJ m 1227984.9333 691316.9377 2644083.4857 0.0
DBA/2J m 1657679.775 598698.0301 2884057.0956 431302.4544




  GWAS USING LINEAR MIXED MODELS