Phenotype measure:   HMDPpheno7   ketogulonate

ID, description, units MPD:50216   ketogulonate   liver 2-ketogulonate (16h fast), relative abundance  
Data set, strains HMDPpheno7   HMDP   97 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno7 - liver 2-ketogulonate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested97 strains
Mean of the strain means276729   None
Median of the strain means251766   None
SD of the strain means± 146135
Coefficient of variation (CV)0.528
Min–max range of strain means36773   –   742402   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 19 290458377488.119 15287283025.6905 1.0321 0.4565
Residuals 31 459156339526.771 14811494823.4442


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 168526.0 0.0   1   0.0 0.0 168526.0, 168526.0 -0.74
A/J m 202630.0 71607.0   2   50634.0 0.353 151997.0, 253264.0 -0.51
AKR/J m 87128.0 0.0   1   0.0 0.0 87128.0, 87128.0 -1.3
AXB10/PgnJ m 406111.0 0.0   1   0.0 0.0 406111.0, 406111.0 0.89
AXB12/PgnJ m 167596.0 0.0   1   0.0 0.0 167596.0, 167596.0 -0.75
AXB13/PgnJ m 404440.0 0.0   1   0.0 0.0 404440.0, 404440.0 0.87
AXB15/PgnJ m 254013.0 0.0   1   0.0 0.0 254013.0, 254013.0 -0.16
AXB19a/PgnJ m 159221.0 0.0   1   0.0 0.0 159221.0, 159221.0 -0.8
AXB19b/PgnJ m 299447.0 104541.0   2   73922.0 0.349 225525.0, 373369.0 0.16
AXB19/PgnJ m 353394.0 0.0   1   0.0 0.0 353394.0, 353394.0 0.52
AXB1/PgnJ m 177824.0 0.0   1   0.0 0.0 177824.0, 177824.0 -0.68
AXB23/PgnJ m 215636.0 0.0   1   0.0 0.0 215636.0, 215636.0 -0.42
AXB24/PgnJ m 133110.0 0.0   1   0.0 0.0 133110.0, 133110.0 -0.98
AXB2/PgnJ m 273531.0 0.0   1   0.0 0.0 273531.0, 273531.0 -0.02
AXB4/PgnJ m 36773.0 0.0   1   0.0 0.0 36773.0, 36773.0 -1.64
AXB5/PgnJ m 105272.0 0.0   1   0.0 0.0 105272.0, 105272.0 -1.17
AXB8/PgnJ m 251338.0 0.0   1   0.0 0.0 251338.0, 251338.0 -0.17
BALB/cJ m 219850.0 49968.0   2   35333.0 0.227 184517.0, 255182.0 -0.39
BUB/BnJ m 252515.0 0.0   1   0.0 0.0 252515.0, 252515.0 -0.17
BXA11/PgnJ m 229076.0 0.0   1   0.0 0.0 229076.0, 229076.0 -0.33
BXA12/PgnJ m 235375.0 0.0   1   0.0 0.0 235375.0, 235375.0 -0.28
BXA13/PgnJ m 234747.0 0.0   1   0.0 0.0 234747.0, 234747.0 -0.29
BXA14/PgnJ m 196992.0 0.0   1   0.0 0.0 196992.0, 196992.0 -0.55
BXA16/PgnJ m 414203.0 216624.0   2   153176.0 0.523 261027.0, 567379.0 0.94
BXA1/PgnJ m 274197.0 0.0   1   0.0 0.0 274197.0, 274197.0 -0.02
BXA24/PgnJ m 251427.0 0.0   1   0.0 0.0 251427.0, 251427.0 -0.17
BXA25/PgnJ m 227762.0 0.0   1   0.0 0.0 227762.0, 227762.0 -0.34
BXA26/PgnJ m 351719.0 0.0   1   0.0 0.0 351719.0, 351719.0 0.51
BXA2/PgnJ m 344997.0 0.0   1   0.0 0.0 344997.0, 344997.0 0.47
BXA4/PgnJ m 139038.0 0.0   1   0.0 0.0 139038.0, 139038.0 -0.94
BXA7/PgnJ m 184153.0 0.0   1   0.0 0.0 184153.0, 184153.0 -0.63
BXA8/PgnJ m 176244.0 0.0   1   0.0 0.0 176244.0, 176244.0 -0.69
BXD11/TyJ m 322199.0 0.0   1   0.0 0.0 322199.0, 322199.0 0.31
BXD12/TyJ m 317294.0 0.0   1   0.0 0.0 317294.0, 317294.0 0.28
BXD13/TyJ m 294597.0 0.0   1   0.0 0.0 294597.0, 294597.0 0.12
BXD14/TyJ m 231866.0 0.0   1   0.0 0.0 231866.0, 231866.0 -0.31
BXD15/TyJ m 368487.0 0.0   1   0.0 0.0 368487.0, 368487.0 0.63
BXD18/TyJ m 260376.0 0.0   1   0.0 0.0 260376.0, 260376.0 -0.11
BXD19/TyJ m 493211.0 520401.0   2   367979.0 1.06 125232.0, 861191.0 1.48
BXD1/TyJ m 646468.0 0.0   1   0.0 0.0 646468.0, 646468.0 2.53
BXD20/TyJ m 497154.0 0.0   1   0.0 0.0 497154.0, 497154.0 1.51
BXD22/TyJ m 311971.0 0.0   1   0.0 0.0 311971.0, 311971.0 0.24
BXD24/TyJ m 394063.0 0.0   1   0.0 0.0 394063.0, 394063.0 0.8
BXD24/TyJ-Cep290rd16/J m 538809.0 0.0   1   0.0 0.0 538809.0, 538809.0 1.79
BXD28/TyJ m 255528.0 7538.0   2   5330.0 0.0295 250198.0, 260859.0 -0.15
BXD29-Tlr4lps-2J/J m 521181.0 0.0   1   0.0 0.0 521181.0, 521181.0 1.67
BXD32/TyJ m 305908.0 0.0   1   0.0 0.0 305908.0, 305908.0 0.2
BXD33/TyJ m 580154.0 0.0   1   0.0 0.0 580154.0, 580154.0 2.08
BXD34/TyJ m 135709.0 0.0   1   0.0 0.0 135709.0, 135709.0 -0.97
BXD36/TyJ m 104664.0 0.0   1   0.0 0.0 104664.0, 104664.0 -1.18
BXD38/TyJ m 742402.0 0.0   1   0.0 0.0 742402.0, 742402.0 3.19
BXD39/TyJ m 566628.0 0.0   1   0.0 0.0 566628.0, 566628.0 1.98
BXD40/TyJ m 88497.0 0.0   1   0.0 0.0 88497.0, 88497.0 -1.29
BXD42/TyJ m 493028.0 0.0   1   0.0 0.0 493028.0, 493028.0 1.48
BXD5/TyJ m 531385.0 0.0   1   0.0 0.0 531385.0, 531385.0 1.74
BXD8/TyJ m 683757.0 0.0   1   0.0 0.0 683757.0, 683757.0 2.79
BXH10/TyJ m 68850.0 0.0   1   0.0 0.0 68850.0, 68850.0 -1.42
BXH19/TyJ m 146210.0 0.0   1   0.0 0.0 146210.0, 146210.0 -0.89
BXH20/KccJ m 183484.0 0.0   1   0.0 0.0 183484.0, 183484.0 -0.64
BXH22/KccJ m 154657.0 0.0   1   0.0 0.0 154657.0, 154657.0 -0.84
BXH2/TyJ m 143097.0 0.0   1   0.0 0.0 143097.0, 143097.0 -0.91
BXH4/TyJ m 95426.0 0.0   1   0.0 0.0 95426.0, 95426.0 -1.24
BXH8/TyJ m 178427.0 0.0   1   0.0 0.0 178427.0, 178427.0 -0.67
BXH9/TyJ m 144125.0 0.0   1   0.0 0.0 144125.0, 144125.0 -0.91
C3H/HeJ m 181402.0 5395.0   2   3815.0 0.0297 177588.0, 185217.0 -0.65
C57BL/6J m 267802.0 41605.0   5 18606.0 0.155 240675.0, 340519.0 -0.06
C57L/J m 202469.0 0.0   1   0.0 0.0 202469.0, 202469.0 -0.51
CAST/EiJ m 220984.0 0.0   1   0.0 0.0 220984.0, 220984.0 -0.38
CBA/J m 255556.0 0.0   1   0.0 0.0 255556.0, 255556.0 -0.14
CE/J m 179440.0 0.0   1   0.0 0.0 179440.0, 179440.0 -0.67
CXB11/HiAJ m 165463.0 93348.0   2   66007.0 0.564 99456.0, 231470.0 -0.76
CXB12/HiAJ m 273080.0 23857.0   2   16870.0 0.0874 256211.0, 289950.0 -0.02
CXB13/HiAJ m 215162.0 84370.0   3 48711.0 0.392 130182.0, 298909.0 -0.42
CXB1/ByJ m 253600.0 40433.0   3 23344.0 0.159 212626.0, 293469.0 -0.16
CXB2/ByJ m 294184.0 40655.0   3 23472.0 0.138 247243.0, 318131.0 0.12
CXB3/ByJ m 437841.0 104559.0   2   73934.0 0.239 363907.0, 511775.0 1.1
CXB4/ByJ m 308339.0 115080.0   2   81374.0 0.373 226965.0, 389712.0 0.22
CXB6/ByJ m 297065.0 39301.0   3 22690.0 0.132 255101.0, 333008.0 0.14
CXB7/ByJ m 372939.0 74282.0   2   52526.0 0.199 320414.0, 425465.0 0.66
CXB8/HiAJ m 247087.0 136028.0   3 78536.0 0.551 108076.0, 379922.0 -0.2
CXB9/HiAJ m 282830.0 76515.0   3 44176.0 0.271 227356.0, 370120.0 0.04
DBA/2J m 332195.0 37664.0   4 18832.0 0.113 285011.0, 374946.0 0.38
FVB/NJ m 114272.0 0.0   1   0.0 0.0 114272.0, 114272.0 -1.11
I/LnJ m 119158.0 0.0   1   0.0 0.0 119158.0, 119158.0 -1.08
KK/HlJ m 250972.0 0.0   1   0.0 0.0 250972.0, 250972.0 -0.18
LG/J m 156132.0 0.0   1   0.0 0.0 156132.0, 156132.0 -0.83
LP/J m 161986.0 0.0   1   0.0 0.0 161986.0, 161986.0 -0.79
MA/MyJ m 342818.0 0.0   1   0.0 0.0 342818.0, 342818.0 0.45
NOD/ShiLtJ m 264205.0 0.0   1   0.0 0.0 264205.0, 264205.0 -0.09
NON/ShiLtJ m 114010.0 0.0   1   0.0 0.0 114010.0, 114010.0 -1.11
NZW/LacJ m 180242.0 0.0   1   0.0 0.0 180242.0, 180242.0 -0.66
PL/J m 251766.0 0.0   1   0.0 0.0 251766.0, 251766.0 -0.17
RIIIS/J m 285190.0 0.0   1   0.0 0.0 285190.0, 285190.0 0.06
SEA/GnJ m 298134.0 0.0   1   0.0 0.0 298134.0, 298134.0 0.15
SJL/J m 150714.0 0.0   1   0.0 0.0 150714.0, 150714.0 -0.86
SM/J m 673963.0 0.0   1   0.0 0.0 673963.0, 673963.0 2.72
SWR/J m 463829.0 0.0   1   0.0 0.0 463829.0, 463829.0 1.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 202630.4 86056.6523 378144.0996 27116.7004
AXB19b/PgnJ m 299446.75 86056.6523 474960.4496 123933.0504
BALB/cJ m 219849.75 86056.6523 395363.4496 44336.0504
BXA16/PgnJ m 414202.65 86056.6523 589716.3496 238688.9504
BXD19/TyJ m 493211.2 86056.6523 668724.8996 317697.5004
BXD28/TyJ m 255528.5 86056.6523 431042.1996 80014.8004
C3H/HeJ m 181402.25 86056.6523 356915.9496 5888.5504
C57BL/6J m 267801.76 54427.0058 378806.3703 156797.1497
CXB11/HiAJ m 165463.0 86056.6523 340976.6996 0.0
CXB12/HiAJ m 273080.35 86056.6523 448594.0496 97566.6504
CXB13/HiAJ m 215162.0333 70264.9624 358468.369 71855.6977
CXB1/ByJ m 253600.3333 70264.9624 396906.669 110293.9977
CXB2/ByJ m 294184.4 70264.9624 437490.7356 150878.0644
CXB3/ByJ m 437841.1 86056.6523 613354.7996 262327.4004
CXB4/ByJ m 308338.6 86056.6523 483852.2996 132824.9004
CXB6/ByJ m 297064.9 70264.9624 440371.2356 153758.5644
CXB7/ByJ m 372939.3 86056.6523 548452.9996 197425.6004
CXB8/HiAJ m 247087.0667 70264.9624 390393.4023 103780.731
CXB9/HiAJ m 282830.2667 70264.9624 426136.6023 139523.931
DBA/2J m 332195.375 60851.2424 456302.3022 208088.4478




  GWAS USING LINEAR MIXED MODELS