Phenotype measure:   HMDPpheno7   lactate

ID, description, units MPD:50213   lactate   liver lactate (16h fast), relative abundance  
Data set, strains HMDPpheno7   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno7 - liver lactate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means28647777   None
Median of the strain means26158098   None
SD of the strain means± 12202342
Coefficient of variation (CV)0.426
Min–max range of strain means8357052   –   65987018   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 8231081604557680.0 391956266883699.0 5.5764 < 0.0001
Residuals 34 2389789130164890.0 70287915593085.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 19772260.0 0.0   1   0.0 0.0 19772260.0, 19772260.0 -0.73
A/J m 33736447.0 10978519.0   2   7762985.0 0.325 25973462.0, 41499432.0 0.42
AKR/J m 24961398.0 0.0   1   0.0 0.0 24961398.0, 24961398.0 -0.3
AXB10/PgnJ m 38890492.0 0.0   1   0.0 0.0 38890492.0, 38890492.0 0.84
AXB12/PgnJ m 17089786.0 0.0   1   0.0 0.0 17089786.0, 17089786.0 -0.95
AXB13/PgnJ m 22156330.0 0.0   1   0.0 0.0 22156330.0, 22156330.0 -0.53
AXB15/PgnJ m 24187560.0 0.0   1   0.0 0.0 24187560.0, 24187560.0 -0.37
AXB19a/PgnJ m 52613404.0 0.0   1   0.0 0.0 52613404.0, 52613404.0 1.96
AXB19b/PgnJ m 43662104.0 9755856.0   2   6898432.0 0.223 36763672.0, 50560536.0 1.23
AXB19/PgnJ m 44824336.0 0.0   1   0.0 0.0 44824336.0, 44824336.0 1.33
AXB1/PgnJ m 14750693.0 0.0   1   0.0 0.0 14750693.0, 14750693.0 -1.14
AXB23/PgnJ m 21575830.0 0.0   1   0.0 0.0 21575830.0, 21575830.0 -0.58
AXB24/PgnJ m 38469470.0 19961260.0   2   14114742.0 0.519 24354728.0, 52584212.0 0.8
AXB2/PgnJ m 13810505.0 0.0   1   0.0 0.0 13810505.0, 13810505.0 -1.22
AXB4/PgnJ m 22738068.0 0.0   1   0.0 0.0 22738068.0, 22738068.0 -0.48
AXB5/PgnJ m 25587872.0 0.0   1   0.0 0.0 25587872.0, 25587872.0 -0.25
AXB6/PgnJ m 23674894.0 0.0   1   0.0 0.0 23674894.0, 23674894.0 -0.41
AXB8/PgnJ m 35059664.0 0.0   1   0.0 0.0 35059664.0, 35059664.0 0.53
BALB/cJ m 26795101.0 10827483.0   3 6251250.0 0.404 18142212.0, 38936916.0 -0.15
BTBR T+ Itpr3tf/J m 28698404.0 0.0   1   0.0 0.0 28698404.0, 28698404.0 0.0
BUB/BnJ m 17475056.0 0.0   1   0.0 0.0 17475056.0, 17475056.0 -0.92
BXA11/PgnJ m 16991642.0 0.0   1   0.0 0.0 16991642.0, 16991642.0 -0.96
BXA12/PgnJ m 12830346.0 0.0   1   0.0 0.0 12830346.0, 12830346.0 -1.3
BXA13/PgnJ m 32042806.0 0.0   1   0.0 0.0 32042806.0, 32042806.0 0.28
BXA14/PgnJ m 62850440.0 0.0   1   0.0 0.0 62850440.0, 62850440.0 2.8
BXA16/PgnJ m 33450844.0 363628.0   2   257124.0 0.0109 33193720.0, 33707968.0 0.39
BXA1/PgnJ m 32490170.0 0.0   1   0.0 0.0 32490170.0, 32490170.0 0.31
BXA24/PgnJ m 44459024.0 0.0   1   0.0 0.0 44459024.0, 44459024.0 1.3
BXA25/PgnJ m 25082920.0 0.0   1   0.0 0.0 25082920.0, 25082920.0 -0.29
BXA26/PgnJ m 31399094.0 0.0   1   0.0 0.0 31399094.0, 31399094.0 0.23
BXA2/PgnJ m 36024836.0 0.0   1   0.0 0.0 36024836.0, 36024836.0 0.6
BXA4/PgnJ m 33424138.0 0.0   1   0.0 0.0 33424138.0, 33424138.0 0.39
BXA7/PgnJ m 30597004.0 0.0   1   0.0 0.0 30597004.0, 30597004.0 0.16
BXA8/PgnJ m 33632100.0 0.0   1   0.0 0.0 33632100.0, 33632100.0 0.41
BXD11/TyJ m 15811837.0 0.0   1   0.0 0.0 15811837.0, 15811837.0 -1.05
BXD12/TyJ m 14188110.0 0.0   1   0.0 0.0 14188110.0, 14188110.0 -1.18
BXD13/TyJ m 27217900.0 0.0   1   0.0 0.0 27217900.0, 27217900.0 -0.12
BXD14/TyJ m 48943916.0 0.0   1   0.0 0.0 48943916.0, 48943916.0 1.66
BXD15/TyJ m 14696699.0 0.0   1   0.0 0.0 14696699.0, 14696699.0 -1.14
BXD18/TyJ m 15903334.0 0.0   1   0.0 0.0 15903334.0, 15903334.0 -1.04
BXD19/TyJ m 27152960.0 426315.0   2   301450.0 0.0157 26851510.0, 27454410.0 -0.12
BXD1/TyJ m 25803700.0 0.0   1   0.0 0.0 25803700.0, 25803700.0 -0.23
BXD20/TyJ m 22312568.0 0.0   1   0.0 0.0 22312568.0, 22312568.0 -0.52
BXD21/TyJ m 25314552.0 0.0   1   0.0 0.0 25314552.0, 25314552.0 -0.27
BXD22/TyJ m 21446184.0 0.0   1   0.0 0.0 21446184.0, 21446184.0 -0.59
BXD24/TyJ m 15741007.0 0.0   1   0.0 0.0 15741007.0, 15741007.0 -1.06
BXD24/TyJ-Cep290rd16/J m 14331209.0 0.0   1   0.0 0.0 14331209.0, 14331209.0 -1.17
BXD28/TyJ m 28061169.0 1444459.0   2   1021387.0 0.0515 27039782.0, 29082556.0 -0.05
BXD29-Tlr4lps-2J/J m 18799274.0 0.0   1   0.0 0.0 18799274.0, 18799274.0 -0.81
BXD2/TyJ m 28222662.0 0.0   1   0.0 0.0 28222662.0, 28222662.0 -0.03
BXD32/TyJ m 27492212.0 0.0   1   0.0 0.0 27492212.0, 27492212.0 -0.09
BXD33/TyJ m 34470132.0 0.0   1   0.0 0.0 34470132.0, 34470132.0 0.48
BXD34/TyJ m 11498528.0 0.0   1   0.0 0.0 11498528.0, 11498528.0 -1.41
BXD36/TyJ m 18630248.0 0.0   1   0.0 0.0 18630248.0, 18630248.0 -0.82
BXD38/TyJ m 11268772.0 0.0   1   0.0 0.0 11268772.0, 11268772.0 -1.42
BXD39/TyJ m 36676252.0 0.0   1   0.0 0.0 36676252.0, 36676252.0 0.66
BXD40/TyJ m 16550459.0 0.0   1   0.0 0.0 16550459.0, 16550459.0 -0.99
BXD42/TyJ m 22768672.0 0.0   1   0.0 0.0 22768672.0, 22768672.0 -0.48
BXD5/TyJ m 41354220.0 0.0   1   0.0 0.0 41354220.0, 41354220.0 1.04
BXD6/TyJ m 27109550.0 0.0   1   0.0 0.0 27109550.0, 27109550.0 -0.13
BXD8/TyJ m 26212270.0 0.0   1   0.0 0.0 26212270.0, 26212270.0 -0.2
BXD9/TyJ m 25068884.0 0.0   1   0.0 0.0 25068884.0, 25068884.0 -0.29
BXH10/TyJ m 26103926.0 0.0   1   0.0 0.0 26103926.0, 26103926.0 -0.21
BXH19/TyJ m 65512216.0 0.0   1   0.0 0.0 65512216.0, 65512216.0 3.02
BXH20/KccJ m 39770616.0 0.0   1   0.0 0.0 39770616.0, 39770616.0 0.91
BXH22/KccJ m 19511440.0 0.0   1   0.0 0.0 19511440.0, 19511440.0 -0.75
BXH2/TyJ m 36333048.0 0.0   1   0.0 0.0 36333048.0, 36333048.0 0.63
BXH4/TyJ m 31709097.0 10598992.0   2   7494619.0 0.334 24214478.0, 39203716.0 0.25
BXH6/TyJ m 38152424.0 0.0   1   0.0 0.0 38152424.0, 38152424.0 0.78
BXH7/TyJ m 20289136.0 0.0   1   0.0 0.0 20289136.0, 20289136.0 -0.69
BXH8/TyJ m 49123024.0 0.0   1   0.0 0.0 49123024.0, 49123024.0 1.68
BXH9/TyJ m 29159598.0 0.0   1   0.0 0.0 29159598.0, 29159598.0 0.04
C3H/HeJ m 34963185.0 6682480.0   2   4725227.0 0.191 30237958.0, 39688412.0 0.52
C57BL/6J m 26407535.0 8355324.0   5 3736615.0 0.316 14653545.0, 37730804.0 -0.18
C57L/J m 8357052.0 0.0   1   0.0 0.0 8357052.0, 8357052.0 -1.66
C58/J m 22546750.0 0.0   1   0.0 0.0 22546750.0, 22546750.0 -0.5
CAST/EiJ m 31731210.0 0.0   1   0.0 0.0 31731210.0, 31731210.0 0.25
CBA/J m 20982618.0 0.0   1   0.0 0.0 20982618.0, 20982618.0 -0.63
CE/J m 24370614.0 0.0   1   0.0 0.0 24370614.0, 24370614.0 -0.35
CXB11/HiAJ m 29345332.0 4065887.0   2   2875016.0 0.139 26470316.0, 32220348.0 0.06
CXB12/HiAJ m 37262828.0 3603671.0   2   2548180.0 0.0967 34714648.0, 39811008.0 0.71
CXB13/HiAJ m 39157765.0 11444017.0   3 6607206.0 0.292 26124914.0, 47564728.0 0.86
CXB1/ByJ m 54484679.0 7860449.0   3 4538232.0 0.144 46378688.0, 62074104.0 2.12
CXB2/ByJ m 28604341.0 10423277.0   3 6017882.0 0.364 16770281.0, 36421628.0 0.0
CXB3/ByJ m 47219054.0 2114382.0   2   1495094.0 0.0448 45723960.0, 48714148.0 1.52
CXB4/ByJ m 65987018.0 10803344.0   2   7639118.0 0.164 58347900.0, 73626136.0 3.06
CXB6/ByJ m 25159224.0 2791747.0   3 1611816.0 0.111 23206452.0, 28356840.0 -0.29
CXB7/ByJ m 49073712.0 1392039.0   2   984320.0 0.0284 48089392.0, 50058032.0 1.67
CXB8/HiAJ m 59177779.0 8860761.0   3 5115763.0 0.15 50442828.0, 68159208.0 2.5
CXB9/HiAJ m 42954265.0 9124860.0   3 5268240.0 0.212 33564116.0, 51788408.0 1.17
DBA/2J m 18416947.0 1628007.0   4 814003.0 0.0884 16275951.0, 20098030.0 -0.84
FVB/NJ m 17990342.0 0.0   1   0.0 0.0 17990342.0, 17990342.0 -0.87
I/LnJ m 26282042.0 0.0   1   0.0 0.0 26282042.0, 26282042.0 -0.19
KK/HlJ m 20063462.0 0.0   1   0.0 0.0 20063462.0, 20063462.0 -0.7
LG/J m 17353338.0 0.0   1   0.0 0.0 17353338.0, 17353338.0 -0.93
LP/J m 23138878.0 0.0   1   0.0 0.0 23138878.0, 23138878.0 -0.45
MA/MyJ m 13369329.0 0.0   1   0.0 0.0 13369329.0, 13369329.0 -1.25
NOD/ShiLtJ m 17756378.0 0.0   1   0.0 0.0 17756378.0, 17756378.0 -0.89
NON/ShiLtJ m 39475308.0 0.0   1   0.0 0.0 39475308.0, 39475308.0 0.89
NZW/LacJ m 24964980.0 0.0   1   0.0 0.0 24964980.0, 24964980.0 -0.3
PL/J m 23889820.0 0.0   1   0.0 0.0 23889820.0, 23889820.0 -0.39
RIIIS/J m 14894400.0 0.0   1   0.0 0.0 14894400.0, 14894400.0 -1.13
SEA/GnJ m 20911404.0 0.0   1   0.0 0.0 20911404.0, 20911404.0 -0.63
SJL/J m 22402192.0 0.0   1   0.0 0.0 22402192.0, 22402192.0 -0.51
SM/J m 15066794.0 0.0   1   0.0 0.0 15066794.0, 15066794.0 -1.11
SWR/J m 38386976.0 0.0   1   0.0 0.0 38386976.0, 38386976.0 0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 33736447.0 5928233.9526 45784067.9001 21688826.0999
AXB19b/PgnJ m 43662104.0 5928233.9526 55709724.9001 31614483.0999
AXB24/PgnJ m 38469470.0 5928233.9526 50517090.9001 26421849.0999
BALB/cJ m 26795101.3333 4840382.7532 36631942.6066 16958260.0601
BXA16/PgnJ m 33450844.0 5928233.9526 45498464.9001 21403223.0999
BXD19/TyJ m 27152960.0 5928233.9526 39200580.9001 15105339.0999
BXD28/TyJ m 28061169.0 5928233.9526 40108789.9001 16013548.0999
BXH4/TyJ m 31709097.0 5928233.9526 43756717.9001 19661476.0999
C3H/HeJ m 34963185.0 5928233.9526 47010805.9001 22915564.0999
C57BL/6J m 26407535.4 3749344.3585 34027119.8861 18787950.9139
CXB11/HiAJ m 29345332.0 5928233.9526 41392952.9001 17297711.0999
CXB12/HiAJ m 37262828.0 5928233.9526 49310448.9001 25215207.0999
CXB13/HiAJ m 39157764.6667 4840382.7532 48994605.9399 29320923.3934
CXB1/ByJ m 54484678.6667 4840382.7532 64321519.9399 44647837.3934
CXB2/ByJ m 28604341.0 4840382.7532 38441182.2732 18767499.7268
CXB3/ByJ m 47219054.0 5928233.9526 59266674.9001 35171433.0999
CXB4/ByJ m 65987018.0 5928233.9526 78034638.9001 53939397.0999
CXB6/ByJ m 25159224.0 4840382.7532 34996065.2732 15322382.7268
CXB7/ByJ m 49073712.0 5928233.9526 61121332.9001 37026091.0999
CXB8/HiAJ m 59177778.6667 4840382.7532 69014619.9399 49340937.3934
CXB9/HiAJ m 42954265.3333 4840382.7532 52791106.6066 33117424.0601
DBA/2J m 18416946.75 4191894.4283 26935901.1856 9897992.3144




  GWAS USING LINEAR MIXED MODELS