Phenotype measure:   HMDPpheno7   sorbitol

ID, description, units MPD:50207   sorbitol   liver sorbitol (16h fast), relative abundance  
Data set, strains HMDPpheno7   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno7 - liver sorbitol (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means359763   None
Median of the strain means303664   None
SD of the strain means± 243626
Coefficient of variation (CV)0.677
Min–max range of strain means34947   –   1315025   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 2475782407187.27 117894400342.251 2.3953 0.0114
Residuals 34 1673422455583.81 49218307517.1708


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 180173.0 0.0   1   0.0 0.0 180173.0, 180173.0 -0.74
A/J m 190366.0 192135.0   2   135860.0 1.01 54506.0, 326226.0 -0.7
AKR/J m 272733.0 0.0   1   0.0 0.0 272733.0, 272733.0 -0.36
AXB10/PgnJ m 401018.0 0.0   1   0.0 0.0 401018.0, 401018.0 0.17
AXB12/PgnJ m 195986.0 0.0   1   0.0 0.0 195986.0, 195986.0 -0.67
AXB13/PgnJ m 550206.0 0.0   1   0.0 0.0 550206.0, 550206.0 0.78
AXB15/PgnJ m 138635.0 0.0   1   0.0 0.0 138635.0, 138635.0 -0.91
AXB19a/PgnJ m 531659.0 0.0   1   0.0 0.0 531659.0, 531659.0 0.71
AXB19b/PgnJ m 465831.0 143400.0   2   101399.0 0.308 364432.0, 567230.0 0.44
AXB19/PgnJ m 466970.0 0.0   1   0.0 0.0 466970.0, 466970.0 0.44
AXB1/PgnJ m 54047.0 0.0   1   0.0 0.0 54047.0, 54047.0 -1.25
AXB23/PgnJ m 263780.0 0.0   1   0.0 0.0 263780.0, 263780.0 -0.39
AXB24/PgnJ m 750605.0 785581.0   2   555490.0 1.05 195116.0, 1306095.0 1.6
AXB2/PgnJ m 73279.0 0.0   1   0.0 0.0 73279.0, 73279.0 -1.18
AXB4/PgnJ m 300355.0 0.0   1   0.0 0.0 300355.0, 300355.0 -0.24
AXB5/PgnJ m 432566.0 0.0   1   0.0 0.0 432566.0, 432566.0 0.3
AXB6/PgnJ m 440530.0 0.0   1   0.0 0.0 440530.0, 440530.0 0.33
AXB8/PgnJ m 253922.0 0.0   1   0.0 0.0 253922.0, 253922.0 -0.43
BALB/cJ m 276504.0 196276.0   3 113320.0 0.71 66590.0, 455464.0 -0.34
BTBR T+ Itpr3tf/J m 456544.0 0.0   1   0.0 0.0 456544.0, 456544.0 0.4
BUB/BnJ m 79275.0 0.0   1   0.0 0.0 79275.0, 79275.0 -1.15
BXA11/PgnJ m 293452.0 0.0   1   0.0 0.0 293452.0, 293452.0 -0.27
BXA12/PgnJ m 59403.0 0.0   1   0.0 0.0 59403.0, 59403.0 -1.23
BXA13/PgnJ m 178131.0 0.0   1   0.0 0.0 178131.0, 178131.0 -0.75
BXA14/PgnJ m 654762.0 0.0   1   0.0 0.0 654762.0, 654762.0 1.21
BXA16/PgnJ m 422238.0 189660.0   2   134110.0 0.449 288128.0, 556347.0 0.26
BXA1/PgnJ m 712151.0 0.0   1   0.0 0.0 712151.0, 712151.0 1.45
BXA24/PgnJ m 684589.0 0.0   1   0.0 0.0 684589.0, 684589.0 1.33
BXA25/PgnJ m 145714.0 0.0   1   0.0 0.0 145714.0, 145714.0 -0.88
BXA26/PgnJ m 314965.0 0.0   1   0.0 0.0 314965.0, 314965.0 -0.18
BXA2/PgnJ m 783845.0 0.0   1   0.0 0.0 783845.0, 783845.0 1.74
BXA4/PgnJ m 165529.0 0.0   1   0.0 0.0 165529.0, 165529.0 -0.8
BXA7/PgnJ m 545265.0 0.0   1   0.0 0.0 545265.0, 545265.0 0.76
BXA8/PgnJ m 514229.0 0.0   1   0.0 0.0 514229.0, 514229.0 0.63
BXD11/TyJ m 92013.0 0.0   1   0.0 0.0 92013.0, 92013.0 -1.1
BXD12/TyJ m 126382.0 0.0   1   0.0 0.0 126382.0, 126382.0 -0.96
BXD13/TyJ m 654907.0 0.0   1   0.0 0.0 654907.0, 654907.0 1.21
BXD14/TyJ m 458039.0 0.0   1   0.0 0.0 458039.0, 458039.0 0.4
BXD15/TyJ m 460694.0 0.0   1   0.0 0.0 460694.0, 460694.0 0.41
BXD18/TyJ m 216463.0 0.0   1   0.0 0.0 216463.0, 216463.0 -0.59
BXD19/TyJ m 497838.0 198313.0   2   140229.0 0.398 357610.0, 638067.0 0.57
BXD1/TyJ m 579836.0 0.0   1   0.0 0.0 579836.0, 579836.0 0.9
BXD20/TyJ m 457532.0 0.0   1   0.0 0.0 457532.0, 457532.0 0.4
BXD21/TyJ m 164721.0 0.0   1   0.0 0.0 164721.0, 164721.0 -0.8
BXD22/TyJ m 922671.0 0.0   1   0.0 0.0 922671.0, 922671.0 2.31
BXD24/TyJ m 146563.0 0.0   1   0.0 0.0 146563.0, 146563.0 -0.88
BXD24/TyJ-Cep290rd16/J m 306636.0 0.0   1   0.0 0.0 306636.0, 306636.0 -0.22
BXD28/TyJ m 583460.0 261911.0   2   185199.0 0.449 398261.0, 768659.0 0.92
BXD29-Tlr4lps-2J/J m 237038.0 0.0   1   0.0 0.0 237038.0, 237038.0 -0.5
BXD2/TyJ m 332149.0 0.0   1   0.0 0.0 332149.0, 332149.0 -0.11
BXD32/TyJ m 533822.0 0.0   1   0.0 0.0 533822.0, 533822.0 0.71
BXD33/TyJ m 246905.0 0.0   1   0.0 0.0 246905.0, 246905.0 -0.46
BXD34/TyJ m 108977.0 0.0   1   0.0 0.0 108977.0, 108977.0 -1.03
BXD36/TyJ m 278717.0 0.0   1   0.0 0.0 278717.0, 278717.0 -0.33
BXD38/TyJ m 35088.0 0.0   1   0.0 0.0 35088.0, 35088.0 -1.33
BXD39/TyJ m 692913.0 0.0   1   0.0 0.0 692913.0, 692913.0 1.37
BXD40/TyJ m 167804.0 0.0   1   0.0 0.0 167804.0, 167804.0 -0.79
BXD42/TyJ m 492100.0 0.0   1   0.0 0.0 492100.0, 492100.0 0.54
BXD5/TyJ m 764235.0 0.0   1   0.0 0.0 764235.0, 764235.0 1.66
BXD6/TyJ m 927422.0 0.0   1   0.0 0.0 927422.0, 927422.0 2.33
BXD8/TyJ m 86330.0 0.0   1   0.0 0.0 86330.0, 86330.0 -1.12
BXD9/TyJ m 667441.0 0.0   1   0.0 0.0 667441.0, 667441.0 1.26
BXH10/TyJ m 313539.0 0.0   1   0.0 0.0 313539.0, 313539.0 -0.19
BXH19/TyJ m 361185.0 0.0   1   0.0 0.0 361185.0, 361185.0 0.01
BXH20/KccJ m 774787.0 0.0   1   0.0 0.0 774787.0, 774787.0 1.7
BXH22/KccJ m 376967.0 0.0   1   0.0 0.0 376967.0, 376967.0 0.07
BXH2/TyJ m 662204.0 0.0   1   0.0 0.0 662204.0, 662204.0 1.24
BXH4/TyJ m 1093419.0 202619.0   2   143273.0 0.185 950146.0, 1236692.0 3.01
BXH6/TyJ m 1315025.0 0.0   1   0.0 0.0 1315025.0, 1315025.0 3.92
BXH7/TyJ m 416707.0 0.0   1   0.0 0.0 416707.0, 416707.0 0.23
BXH8/TyJ m 605808.0 0.0   1   0.0 0.0 605808.0, 605808.0 1.01
BXH9/TyJ m 245374.0 0.0   1   0.0 0.0 245374.0, 245374.0 -0.47
C3H/HeJ m 177345.0 55336.0   2   39128.0 0.312 138217.0, 216473.0 -0.75
C57BL/6J m 191252.0 120342.0   5 53818.0 0.629 73044.0, 355013.0 -0.69
C57L/J m 34947.0 0.0   1   0.0 0.0 34947.0, 34947.0 -1.33
C58/J m 214634.0 0.0   1   0.0 0.0 214634.0, 214634.0 -0.6
CAST/EiJ m 316529.0 0.0   1   0.0 0.0 316529.0, 316529.0 -0.18
CBA/J m 318863.0 0.0   1   0.0 0.0 318863.0, 318863.0 -0.17
CE/J m 94994.0 0.0   1   0.0 0.0 94994.0, 94994.0 -1.09
CXB11/HiAJ m 202736.0 108455.0   2   76689.0 0.535 126048.0, 279425.0 -0.64
CXB12/HiAJ m 233716.0 3504.0   2   2478.0 0.015 231238.0, 236193.0 -0.52
CXB13/HiAJ m 441678.0 220027.0   3 127033.0 0.498 188421.0, 585834.0 0.34
CXB1/ByJ m 437981.0 135206.0   3 78061.0 0.309 299533.0, 569692.0 0.32
CXB2/ByJ m 364953.0 437771.0   3 252747.0 1.2 75756.0, 868602.0 0.02
CXB3/ByJ m 474353.0 77118.0   2   54531.0 0.163 419822.0, 528883.0 0.47
CXB4/ByJ m 737660.0 29684.0   2   20989.0 0.0402 716670.0, 758649.0 1.55
CXB6/ByJ m 234045.0 183641.0   3 106025.0 0.785 125009.0, 446067.0 -0.52
CXB7/ByJ m 380763.0 175529.0   2   124118.0 0.461 256645.0, 504880.0 0.09
CXB8/HiAJ m 395939.0 63883.0   3 36883.0 0.161 347236.0, 468269.0 0.15
CXB9/HiAJ m 300692.0 89786.0   3 51838.0 0.299 197880.0, 363660.0 -0.24
DBA/2J m 153596.0 77455.0   4 38727.0 0.504 77706.0, 223376.0 -0.85
FVB/NJ m 102591.0 0.0   1   0.0 0.0 102591.0, 102591.0 -1.06
I/LnJ m 126829.0 0.0   1   0.0 0.0 126829.0, 126829.0 -0.96
KK/HlJ m 149806.0 0.0   1   0.0 0.0 149806.0, 149806.0 -0.86
LG/J m 276237.0 0.0   1   0.0 0.0 276237.0, 276237.0 -0.34
LP/J m 243238.0 0.0   1   0.0 0.0 243238.0, 243238.0 -0.48
MA/MyJ m 88052.0 0.0   1   0.0 0.0 88052.0, 88052.0 -1.12
NOD/ShiLtJ m 71842.0 0.0   1   0.0 0.0 71842.0, 71842.0 -1.18
NON/ShiLtJ m 155632.0 0.0   1   0.0 0.0 155632.0, 155632.0 -0.84
NZW/LacJ m 376121.0 0.0   1   0.0 0.0 376121.0, 376121.0 0.07
PL/J m 147094.0 0.0   1   0.0 0.0 147094.0, 147094.0 -0.87
RIIIS/J m 315941.0 0.0   1   0.0 0.0 315941.0, 315941.0 -0.18
SEA/GnJ m 129452.0 0.0   1   0.0 0.0 129452.0, 129452.0 -0.95
SJL/J m 259791.0 0.0   1   0.0 0.0 259791.0, 259791.0 -0.41
SM/J m 41528.0 0.0   1   0.0 0.0 41528.0, 41528.0 -1.31
SWR/J m 291050.0 0.0   1   0.0 0.0 291050.0, 291050.0 -0.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 190366.25 156873.0498 509170.6441 0.0
AXB19b/PgnJ m 465830.9 156873.0498 784635.2941 147026.5059
AXB24/PgnJ m 750605.3 156873.0498 1069409.6941 431800.9059
BALB/cJ m 276504.2333 128086.3088 536806.9311 16201.5355
BXA16/PgnJ m 422237.6 156873.0498 741041.9941 103433.2059
BXD19/TyJ m 497838.45 156873.0498 816642.8441 179034.0559
BXD28/TyJ m 583460.05 156873.0498 902264.4441 264655.6559
BXH4/TyJ m 1093419.35 156873.0498 1412223.7441 774614.9559
C3H/HeJ m 177344.85 156873.0498 496149.2441 0.0
C57BL/6J m 191252.28 99215.2282 392881.8827 0.0
CXB11/HiAJ m 202736.45 156873.0498 521540.8441 0.0
CXB12/HiAJ m 233715.55 156873.0498 552519.9441 0.0
CXB13/HiAJ m 441678.3667 128086.3088 701981.0645 181375.6689
CXB1/ByJ m 437981.3667 128086.3088 698284.0645 177678.6689
CXB2/ByJ m 364952.9 128086.3088 625255.5978 104650.2022
CXB3/ByJ m 474352.65 156873.0498 793157.0441 155548.2559
CXB4/ByJ m 737659.55 156873.0498 1056463.9441 418855.1559
CXB6/ByJ m 234045.2667 128086.3088 494347.9645 0.0
CXB7/ByJ m 380762.55 156873.0498 699566.9441 61958.1559
CXB8/HiAJ m 395938.6333 128086.3088 656241.3311 135635.9355
CXB9/HiAJ m 300692.0333 128086.3088 560994.7311 40389.3355
DBA/2J m 153595.75 110925.9973 379024.499 0.0




  GWAS USING LINEAR MIXED MODELS