Phenotype measure:   HMDPpheno7   fructose

ID, description, units MPD:50204   fructose   liver fructose (16h fast), relative abundance  
Data set, strains HMDPpheno7   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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HMDPpheno7 - liver fructose (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means1575489   None
Median of the strain means1485589   None
SD of the strain means± 517412
Coefficient of variation (CV)0.328
Min–max range of strain means484072   –   3451557   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 9642889263768.55 459185203036.598 2.015 0.0335
Residuals 34 7748059069566.5 227884090281.368


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 1320732.0 0.0   1   0.0 0.0 1320732.0, 1320732.0 -0.49
A/J m 1584230.0 329237.0   2   232806.0 0.208 1351425.0, 1817036.0 0.02
AKR/J m 1451237.0 0.0   1   0.0 0.0 1451237.0, 1451237.0 -0.24
AXB10/PgnJ m 1575336.0 0.0   1   0.0 0.0 1575336.0, 1575336.0 0.0
AXB12/PgnJ m 1322288.0 0.0   1   0.0 0.0 1322288.0, 1322288.0 -0.49
AXB13/PgnJ m 1358816.0 0.0   1   0.0 0.0 1358816.0, 1358816.0 -0.42
AXB15/PgnJ m 1530332.0 0.0   1   0.0 0.0 1530332.0, 1530332.0 -0.09
AXB19a/PgnJ m 2408636.0 0.0   1   0.0 0.0 2408636.0, 2408636.0 1.61
AXB19b/PgnJ m 1978050.0 65086.0   2   46022.0 0.0329 1932028.0, 2024073.0 0.78
AXB19/PgnJ m 2212124.0 0.0   1   0.0 0.0 2212124.0, 2212124.0 1.23
AXB1/PgnJ m 1173824.0 0.0   1   0.0 0.0 1173824.0, 1173824.0 -0.78
AXB23/PgnJ m 1634939.0 0.0   1   0.0 0.0 1634939.0, 1634939.0 0.11
AXB24/PgnJ m 2446540.0 2012630.0   2   1423144.0 0.823 1023396.0, 3869684.0 1.68
AXB2/PgnJ m 1053037.0 0.0   1   0.0 0.0 1053037.0, 1053037.0 -1.01
AXB4/PgnJ m 1759577.0 0.0   1   0.0 0.0 1759577.0, 1759577.0 0.36
AXB5/PgnJ m 1556241.0 0.0   1   0.0 0.0 1556241.0, 1556241.0 -0.04
AXB6/PgnJ m 1851661.0 0.0   1   0.0 0.0 1851661.0, 1851661.0 0.53
AXB8/PgnJ m 1251336.0 0.0   1   0.0 0.0 1251336.0, 1251336.0 -0.63
BALB/cJ m 1350337.0 374549.0   3 216246.0 0.277 924594.0, 1629122.0 -0.44
BTBR T+ Itpr3tf/J m 2602004.0 0.0   1   0.0 0.0 2602004.0, 2602004.0 1.98
BUB/BnJ m 972360.0 0.0   1   0.0 0.0 972360.0, 972360.0 -1.17
BXA11/PgnJ m 1497640.0 0.0   1   0.0 0.0 1497640.0, 1497640.0 -0.15
BXA12/PgnJ m 484072.0 0.0   1   0.0 0.0 484072.0, 484072.0 -2.11
BXA13/PgnJ m 1236348.0 0.0   1   0.0 0.0 1236348.0, 1236348.0 -0.66
BXA14/PgnJ m 3451557.0 0.0   1   0.0 0.0 3451557.0, 3451557.0 3.63
BXA16/PgnJ m 1722964.0 874096.0   2   618079.0 0.507 1104884.0, 2341043.0 0.29
BXA1/PgnJ m 1767379.0 0.0   1   0.0 0.0 1767379.0, 1767379.0 0.37
BXA24/PgnJ m 1925763.0 0.0   1   0.0 0.0 1925763.0, 1925763.0 0.68
BXA25/PgnJ m 1354684.0 0.0   1   0.0 0.0 1354684.0, 1354684.0 -0.43
BXA26/PgnJ m 1320520.0 0.0   1   0.0 0.0 1320520.0, 1320520.0 -0.49
BXA2/PgnJ m 2746676.0 0.0   1   0.0 0.0 2746676.0, 2746676.0 2.26
BXA4/PgnJ m 956912.0 0.0   1   0.0 0.0 956912.0, 956912.0 -1.2
BXA7/PgnJ m 1879448.0 0.0   1   0.0 0.0 1879448.0, 1879448.0 0.59
BXA8/PgnJ m 1393222.0 0.0   1   0.0 0.0 1393222.0, 1393222.0 -0.35
BXD11/TyJ m 856933.0 0.0   1   0.0 0.0 856933.0, 856933.0 -1.39
BXD12/TyJ m 1304213.0 0.0   1   0.0 0.0 1304213.0, 1304213.0 -0.52
BXD13/TyJ m 1986067.0 0.0   1   0.0 0.0 1986067.0, 1986067.0 0.79
BXD14/TyJ m 1632376.0 0.0   1   0.0 0.0 1632376.0, 1632376.0 0.11
BXD15/TyJ m 1510333.0 0.0   1   0.0 0.0 1510333.0, 1510333.0 -0.13
BXD18/TyJ m 1292573.0 0.0   1   0.0 0.0 1292573.0, 1292573.0 -0.55
BXD19/TyJ m 1473538.0 13302.0   2   9406.0 0.00903 1464132.0, 1482943.0 -0.2
BXD1/TyJ m 2294920.0 0.0   1   0.0 0.0 2294920.0, 2294920.0 1.39
BXD20/TyJ m 2202538.0 0.0   1   0.0 0.0 2202538.0, 2202538.0 1.21
BXD21/TyJ m 1653511.0 0.0   1   0.0 0.0 1653511.0, 1653511.0 0.15
BXD22/TyJ m 2770584.0 0.0   1   0.0 0.0 2770584.0, 2770584.0 2.31
BXD24/TyJ m 1128238.0 0.0   1   0.0 0.0 1128238.0, 1128238.0 -0.86
BXD24/TyJ-Cep290rd16/J m 1173998.0 0.0   1   0.0 0.0 1173998.0, 1173998.0 -0.78
BXD28/TyJ m 2071410.0 786419.0   2   556082.0 0.38 1515328.0, 2627492.0 0.96
BXD29-Tlr4lps-2J/J m 1465934.0 0.0   1   0.0 0.0 1465934.0, 1465934.0 -0.21
BXD2/TyJ m 1524265.0 0.0   1   0.0 0.0 1524265.0, 1524265.0 -0.1
BXD32/TyJ m 1563937.0 0.0   1   0.0 0.0 1563937.0, 1563937.0 -0.02
BXD33/TyJ m 1394362.0 0.0   1   0.0 0.0 1394362.0, 1394362.0 -0.35
BXD34/TyJ m 1046854.0 0.0   1   0.0 0.0 1046854.0, 1046854.0 -1.02
BXD36/TyJ m 1061944.0 0.0   1   0.0 0.0 1061944.0, 1061944.0 -0.99
BXD38/TyJ m 694788.0 0.0   1   0.0 0.0 694788.0, 694788.0 -1.7
BXD39/TyJ m 2513680.0 0.0   1   0.0 0.0 2513680.0, 2513680.0 1.81
BXD40/TyJ m 928034.0 0.0   1   0.0 0.0 928034.0, 928034.0 -1.25
BXD42/TyJ m 1894061.0 0.0   1   0.0 0.0 1894061.0, 1894061.0 0.62
BXD5/TyJ m 1982189.0 0.0   1   0.0 0.0 1982189.0, 1982189.0 0.79
BXD6/TyJ m 1862666.0 0.0   1   0.0 0.0 1862666.0, 1862666.0 0.56
BXD8/TyJ m 1423400.0 0.0   1   0.0 0.0 1423400.0, 1423400.0 -0.29
BXD9/TyJ m 1866011.0 0.0   1   0.0 0.0 1866011.0, 1866011.0 0.56
BXH10/TyJ m 944183.0 0.0   1   0.0 0.0 944183.0, 944183.0 -1.22
BXH19/TyJ m 2493864.0 0.0   1   0.0 0.0 2493864.0, 2493864.0 1.77
BXH20/KccJ m 1946817.0 0.0   1   0.0 0.0 1946817.0, 1946817.0 0.72
BXH22/KccJ m 1654300.0 0.0   1   0.0 0.0 1654300.0, 1654300.0 0.15
BXH2/TyJ m 1955793.0 0.0   1   0.0 0.0 1955793.0, 1955793.0 0.74
BXH4/TyJ m 2662510.0 10132.0   2   7164.0 0.00381 2655346.0, 2669674.0 2.1
BXH6/TyJ m 2390310.0 0.0   1   0.0 0.0 2390310.0, 2390310.0 1.57
BXH7/TyJ m 1539227.0 0.0   1   0.0 0.0 1539227.0, 1539227.0 -0.07
BXH8/TyJ m 2535524.0 0.0   1   0.0 0.0 2535524.0, 2535524.0 1.86
BXH9/TyJ m 1393184.0 0.0   1   0.0 0.0 1393184.0, 1393184.0 -0.35
C3H/HeJ m 1549016.0 90891.0   2   64270.0 0.0587 1484746.0, 1613286.0 -0.05
C57BL/6J m 1306093.0 277062.0   5 123906.0 0.212 972742.0, 1719415.0 -0.52
C57L/J m 692433.0 0.0   1   0.0 0.0 692433.0, 692433.0 -1.71
C58/J m 2190465.0 0.0   1   0.0 0.0 2190465.0, 2190465.0 1.19
CAST/EiJ m 1390729.0 0.0   1   0.0 0.0 1390729.0, 1390729.0 -0.36
CBA/J m 1513938.0 0.0   1   0.0 0.0 1513938.0, 1513938.0 -0.12
CE/J m 1220877.0 0.0   1   0.0 0.0 1220877.0, 1220877.0 -0.69
CXB11/HiAJ m 972035.0 283821.0   2   200692.0 0.292 771343.0, 1172726.0 -1.17
CXB12/HiAJ m 1224910.0 174864.0   2   123648.0 0.143 1101262.0, 1348558.0 -0.68
CXB13/HiAJ m 1361666.0 347852.0   3 200833.0 0.255 1128594.0, 1761502.0 -0.41
CXB1/ByJ m 1556069.0 158256.0   3 91369.0 0.102 1428014.0, 1732997.0 -0.04
CXB2/ByJ m 1176978.0 340689.0   3 196697.0 0.289 882770.0, 1550246.0 -0.77
CXB3/ByJ m 1576108.0 71603.0   2   50631.0 0.0454 1525478.0, 1626740.0 0.0
CXB4/ByJ m 2196577.0 63349.0   2   44794.0 0.0288 2151783.0, 2241372.0 1.2
CXB6/ByJ m 963315.0 353061.0   3 203840.0 0.367 730217.0, 1369520.0 -1.18
CXB7/ByJ m 1801376.0 149118.0   2   105443.0 0.0828 1695933.0, 1906819.0 0.44
CXB8/HiAJ m 1856602.0 300536.0   3 173514.0 0.162 1629266.0, 2197340.0 0.54
CXB9/HiAJ m 1210882.0 258745.0   3 149386.0 0.214 918322.0, 1409651.0 -0.7
DBA/2J m 1368098.0 353787.0   4 176894.0 0.259 964740.0, 1822628.0 -0.4
FVB/NJ m 1075560.0 0.0   1   0.0 0.0 1075560.0, 1075560.0 -0.97
I/LnJ m 1435017.0 0.0   1   0.0 0.0 1435017.0, 1435017.0 -0.27
KK/HlJ m 1376394.0 0.0   1   0.0 0.0 1376394.0, 1376394.0 -0.38
LG/J m 1294188.0 0.0   1   0.0 0.0 1294188.0, 1294188.0 -0.54
LP/J m 1678889.0 0.0   1   0.0 0.0 1678889.0, 1678889.0 0.2
MA/MyJ m 1180494.0 0.0   1   0.0 0.0 1180494.0, 1180494.0 -0.76
NOD/ShiLtJ m 1111171.0 0.0   1   0.0 0.0 1111171.0, 1111171.0 -0.9
NON/ShiLtJ m 1019451.0 0.0   1   0.0 0.0 1019451.0, 1019451.0 -1.07
NZW/LacJ m 2089776.0 0.0   1   0.0 0.0 2089776.0, 2089776.0 0.99
PL/J m 1174214.0 0.0   1   0.0 0.0 1174214.0, 1174214.0 -0.78
RIIIS/J m 1114140.0 0.0   1   0.0 0.0 1114140.0, 1114140.0 -0.89
SEA/GnJ m 1194663.0 0.0   1   0.0 0.0 1194663.0, 1194663.0 -0.74
SJL/J m 1625165.0 0.0   1   0.0 0.0 1625165.0, 1625165.0 0.1
SM/J m 908217.0 0.0   1   0.0 0.0 908217.0, 908217.0 -1.29
SWR/J m 1376388.0 0.0   1   0.0 0.0 1376388.0, 1376388.0 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 1584230.25 337553.0257 2270220.533 898239.967
AXB19b/PgnJ m 1978050.3 337553.0257 2664040.583 1292060.017
AXB24/PgnJ m 2446540.15 337553.0257 3132530.433 1760549.867
BALB/cJ m 1350336.6333 275610.8913 1910445.354 790227.9127
BXA16/PgnJ m 1722963.6 337553.0257 2408953.883 1036973.317
BXD19/TyJ m 1473537.65 337553.0257 2159527.933 787547.367
BXD28/TyJ m 2071410.2 337553.0257 2757400.483 1385419.917
BXH4/TyJ m 2662510.05 337553.0257 3348500.333 1976519.767
C3H/HeJ m 1549015.65 337553.0257 2235005.933 863025.367
C57BL/6J m 1306093.14 213487.2784 1739951.4894 872234.7906
CXB11/HiAJ m 972034.85 337553.0257 1658025.133 286044.567
CXB12/HiAJ m 1224909.9 337553.0257 1910900.183 538919.617
CXB13/HiAJ m 1361665.5667 275610.8913 1921774.2873 801556.846
CXB1/ByJ m 1556068.7667 275610.8913 2116177.4873 995960.046
CXB2/ByJ m 1176977.9333 275610.8913 1737086.654 616869.2127
CXB3/ByJ m 1576108.5 337553.0257 2262098.783 890118.217
CXB4/ByJ m 2196577.4 337553.0257 2882567.683 1510587.117
CXB6/ByJ m 963314.6667 275610.8913 1523423.3873 403205.946
CXB7/ByJ m 1801375.95 337553.0257 2487366.233 1115385.667
CXB8/HiAJ m 1856602.1667 275610.8913 2416710.8873 1296493.446
CXB9/HiAJ m 1210882.4667 275610.8913 1770991.1873 650773.746
DBA/2J m 1368097.925 238686.0335 1853166.306 883029.544




  GWAS USING LINEAR MIXED MODELS