Project measure / variable:   Harrill2   ALT_trt

ID, description, units MPD:44112   ALT_trt   alanine transaminase (serum ALT)   [IU/L]  DB289  
DB289 study
Data set, strains Harrill2   inbred   34 strains     sex: f     age: 6-8wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Harrill2 - alanine transaminase (serum ALT) DB289



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested34 strains
Mean of the strain means102   IU/L
Median of the strain means102   IU/L
SD of the strain means± 45.5
Coefficient of variation (CV)0.447
Min–max range of strain means25.8   –   207   IU/L
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 329548.0126 9986.3034 8.1323 < 0.0001
Residuals 132 162094.0595 1227.9853


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 123.0 22.7   5 10.2 0.185 83.2, 138.0 0.47
A/J f 207.0 19.9   5 8.91 0.0965 172.0, 220.0 2.32
AKR/J f 131.0 12.7   5 5.68 0.0967 118.0, 146.0 0.65
BALB/cByJ f 40.7 20.5   5 9.15 0.503 18.8, 65.9 -1.34
BTBR T+ Itpr3tf/J f 86.8 20.3   5 9.09 0.234 70.3, 122.0 -0.33
BUB/BnJ f 125.0 30.5   5 13.6 0.243 79.0, 161.0 0.51
C3H/HeJ f 45.3 6.92   5 3.09 0.153 38.1, 56.6 -1.24
C57BL/6J f 82.5 73.8   5 33.0 0.895 40.2, 214.0 -0.42
C57BLKS/J f 71.2 17.3   5 7.75 0.243 60.8, 102.0 -0.67
C57BR/cdJ f 134.0 17.8   4 8.89 0.133 112.0, 149.0 0.71
C58/J f 102.0 71.2   4 35.6 0.696 3.6, 173.0 0.01
CBA/J f 86.4 55.2   5 24.7 0.639 50.9, 178.0 -0.34
CE/J f 116.0 19.5   5 8.71 0.167 95.3, 140.0 0.32
DBA/2J f 76.2 50.6   5 22.6 0.664 37.2, 163.0 -0.56
FVB/NJ f 60.9 21.2   5 9.47 0.348 45.8, 97.3 -0.9
I/LnJ f 57.4 35.8   5 16.0 0.623 29.0, 110.0 -0.97
KK/HlJ f 25.8 8.24   5 3.68 0.319 16.8, 39.2 -1.67
LG/J f 122.0 15.2   5 6.8 0.124 101.0, 137.0 0.45
LP/J f 62.8 16.7   5 7.47 0.266 44.1, 82.3 -0.85
MA/MyJ f 162.0 56.4   5 25.2 0.348 61.2, 193.0 1.33
MRL/MpJ f 179.0 39.7   5 17.8 0.222 139.0, 242.0 1.7
NOD/ShiLtJ f 136.0 51.2   5 22.9 0.375 92.5, 221.0 0.76
NON/ShiLtJ f 63.1 6.72   5 3.0 0.106 54.5, 70.2 -0.85
NOR/LtJ f 142.0 52.2   5 23.4 0.368 86.1, 221.0 0.89
NZW/LacJ f 80.1 28.7   5 12.8 0.358 46.3, 111.0 -0.47
P/J f 125.0 33.0   5 14.8 0.265 87.7, 172.0 0.51
PL/J f 101.0 40.6   5 18.2 0.402 57.6, 147.0 -0.01
PWK/PhJ f 56.9 28.0   5 12.5 0.491 35.6, 106.0 -0.98
RIIIS/J f 32.7 9.2   5 4.11 0.281 21.1, 44.2 -1.52
SEA/GnJ f 122.0 36.9   5 16.5 0.301 79.1, 163.0 0.45
SJL/J f 64.9 20.2   5 9.05 0.312 34.0, 83.9 -0.81
SM/J f 104.0 44.9   5 20.1 0.433 65.8, 180.0 0.05
SWR/J f 135.0 20.3   4 10.2 0.15 105.0, 147.0 0.73
WSB/EiJ f 196.0 34.6   4 17.3 0.177 154.0, 237.0 2.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 122.92 15.6715 153.9198 91.9202
A/J f 206.56 15.6715 237.5598 175.5602
AKR/J f 131.3 15.6715 162.2998 100.3002
BALB/cByJ f 40.66 15.6715 71.6598 9.6602
BTBR T+ Itpr3tf/J f 86.76 15.6715 117.7598 55.7602
BUB/BnJ f 125.48 15.6715 156.4798 94.4802
C3H/HeJ f 45.26 15.6715 76.2598 14.2602
C57BL/6J f 82.46 15.6715 113.4598 51.4602
C57BLKS/J f 71.24 15.6715 102.2398 40.2402
C57BR/cdJ f 133.575 17.5213 168.2339 98.9161
C58/J f 102.35 17.5213 137.0089 67.6911
CBA/J f 86.38 15.6715 117.3798 55.3802
CE/J f 116.5 15.6715 147.4998 85.5002
DBA/2J f 76.18 15.6715 107.1798 45.1802
FVB/NJ f 60.86 15.6715 91.8598 29.8602
I/LnJ f 57.44 15.6715 88.4398 26.4402
KK/HlJ f 25.82 15.6715 56.8198 0.0
LG/J f 122.2 15.6715 153.1998 91.2002
LP/J f 62.78 15.6715 93.7798 31.7802
MA/MyJ f 161.74 15.6715 192.7398 130.7402
MRL/MpJ f 179.06 15.6715 210.0598 148.0602
NOD/ShiLtJ f 136.32 15.6715 167.3198 105.3202
NON/ShiLtJ f 63.1 15.6715 94.0998 32.1002
NOR/LtJ f 141.86 15.6715 172.8598 110.8602
NZW/LacJ f 80.14 15.6715 111.1398 49.1402
P/J f 124.54 15.6715 155.5398 93.5402
PL/J f 100.98 15.6715 131.9798 69.9802
PWK/PhJ f 56.94 15.6715 87.9398 25.9402
RIIIS/J f 32.68 15.6715 63.6798 1.6802
SEA/GnJ f 122.36 15.6715 153.3598 91.3602
SJL/J f 64.94 15.6715 95.9398 33.9402
SM/J f 103.82 15.6715 134.8198 72.8202
SWR/J f 135.05 17.5213 169.7089 100.3911
WSB/EiJ f 195.7 17.5213 230.3589 161.0411




  GWAS USING LINEAR MIXED MODELS