Project measure / variable:   Harrill2   ALT_ctrl

ID, description, units MPD:44111   ALT_ctrl   alanine transaminase (serum ALT)   [IU/L]  control  
DB289 study
Data set, strains Harrill2   inbred   34 strains     sex: f     age: 6-8wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Harrill2 - alanine transaminase (serum ALT) control



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested34 strains
Mean of the strain means29.9   IU/L
Median of the strain means24.4   IU/L
SD of the strain means± 19.2
Coefficient of variation (CV)0.643
Min–max range of strain means11.0   –   86.7   IU/L
Mean sample size per strain5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 60981.4969 1847.9241 7.3692 < 0.0001
Residuals 136 34103.764 250.763


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 16.8 2.82   5 1.26 0.168 11.9, 19.1 -0.68
A/J f 39.3 6.32   5 2.82 0.161 30.8, 46.4 0.49
AKR/J f 16.2 0.965   5 0.432 0.0597 15.1, 17.2 -0.71
BALB/cByJ f 79.9 41.9   5 18.8 0.525 14.5, 126.0 2.6
BTBR T+ Itpr3tf/J f 21.9 6.08   5 2.72 0.278 17.3, 32.4 -0.42
BUB/BnJ f 28.8 13.8   5 6.19 0.48 17.1, 50.0 -0.06
C3H/HeJ f 29.3 20.8   5 9.28 0.709 13.0, 54.4 -0.03
C57BL/6J f 23.6 7.61   5 3.4 0.323 14.6, 34.4 -0.33
C57BLKS/J f 24.6 3.15   5 1.41 0.128 20.5, 28.1 -0.28
C57BR/cdJ f 36.5 8.63   5 3.86 0.237 24.9, 47.8 0.34
C58/J f 36.4 9.63   5 4.31 0.265 20.8, 44.5 0.34
CBA/J f 14.8 2.3   5 1.03 0.155 12.1, 17.3 -0.78
CE/J f 56.2 41.1   5 18.4 0.732 23.1, 116.0 1.37
DBA/2J f 14.1 2.98   5 1.33 0.212 9.5, 17.5 -0.82
FVB/NJ f 33.0 10.8   5 4.84 0.328 22.6, 50.6 0.16
I/LnJ f 13.5 2.67   5 1.19 0.198 11.8, 18.2 -0.85
KK/HlJ f 15.4 4.18   5 1.87 0.272 12.3, 22.5 -0.75
LG/J f 22.4 7.66   5 3.43 0.342 15.7, 35.0 -0.39
LP/J f 23.0 8.87   5 3.97 0.386 8.2, 30.4 -0.36
MA/MyJ f 86.7 30.2   5 13.5 0.348 55.9, 125.0 2.96
MRL/MpJ f 24.1 6.9   5 3.09 0.286 14.9, 34.2 -0.3
NOD/ShiLtJ f 29.2 12.2   5 5.46 0.419 18.1, 47.8 -0.04
NON/ShiLtJ f 13.3 2.33   5 1.04 0.175 10.5, 15.5 -0.86
NOR/LtJ f 15.9 1.81   5 0.81 0.114 14.4, 17.9 -0.73
NZW/LacJ f 15.4 2.32   5 1.04 0.151 13.4, 19.4 -0.75
P/J f 14.7 3.02   5 1.35 0.206 10.4, 18.5 -0.79
PL/J f 25.0 7.21   5 3.23 0.288 17.0, 35.5 -0.25
PWK/PhJ f 56.5 42.6   5 19.1 0.754 25.7, 130.0 1.38
RIIIS/J f 11.0 1.39   5 0.624 0.127 9.5, 13.2 -0.98
SEA/GnJ f 21.5 4.24   5 1.9 0.197 16.5, 26.0 -0.44
SJL/J f 27.8 6.88   5 3.08 0.248 17.4, 36.4 -0.11
SM/J f 27.0 16.5   5 7.38 0.611 15.5, 55.5 -0.15
SWR/J f 28.7 10.5   5 4.71 0.366 15.0, 43.4 -0.06
WSB/EiJ f 73.7 19.7   5 8.79 0.267 43.7, 98.7 2.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 16.82 7.0818 30.8248 2.8152
A/J f 39.32 7.0818 53.3248 25.3152
AKR/J f 16.18 7.0818 30.1848 2.1752
BALB/cByJ f 79.9 7.0818 93.9048 65.8952
BTBR T+ Itpr3tf/J f 21.86 7.0818 35.8648 7.8552
BUB/BnJ f 28.82 7.0818 42.8248 14.8152
C3H/HeJ f 29.28 7.0818 43.2848 15.2752
C57BL/6J f 23.58 7.0818 37.5848 9.5752
C57BLKS/J f 24.64 7.0818 38.6448 10.6352
C57BR/cdJ f 36.48 7.0818 50.4848 22.4752
C58/J f 36.4 7.0818 50.4048 22.3952
CBA/J f 14.8 7.0818 28.8048 0.7952
CE/J f 56.24 7.0818 70.2448 42.2352
DBA/2J f 14.06 7.0818 28.0648 0.0552
FVB/NJ f 32.98 7.0818 46.9848 18.9752
I/LnJ f 13.5 7.0818 27.5048 0.0
KK/HlJ f 15.36 7.0818 29.3648 1.3552
LG/J f 22.4 7.0818 36.4048 8.3952
LP/J f 23.0 7.0818 37.0048 8.9952
MA/MyJ f 86.72 7.0818 100.7248 72.7152
MRL/MpJ f 24.1 7.0818 38.1048 10.0952
NOD/ShiLtJ f 29.16 7.0818 43.1648 15.1552
NON/ShiLtJ f 13.34 7.0818 27.3448 0.0
NOR/LtJ f 15.94 7.0818 29.9448 1.9352
NZW/LacJ f 15.4 7.0818 29.4048 1.3952
P/J f 14.68 7.0818 28.6848 0.6752
PL/J f 25.04 7.0818 39.0448 11.0352
PWK/PhJ f 56.52 7.0818 70.5248 42.5152
RIIIS/J f 11.0 7.0818 25.0048 0.0
SEA/GnJ f 21.52 7.0818 35.5248 7.5152
SJL/J f 27.78 7.0818 41.7848 13.7752
SM/J f 27.02 7.0818 41.0248 13.0152
SWR/J f 28.74 7.0818 42.7448 14.7352
WSB/EiJ f 73.66 7.0818 87.6648 59.6552




  GWAS USING LINEAR MIXED MODELS