Phenotype measure:   Chesler2   pct_dark_deprivation

ID, description, units MPD:43484   pct_dark_deprivation   percentage of time spent sleeping during dark period, following sleep deprivation   [%]
Data set, strains Chesler2   CC diallel w/par   48 strains     sex: both     age: 7-15wks
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  STRAIN COMPARISON PLOT
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Chesler2 - percentage of time spent sleeping during dark period, following sleep deprivation



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 16.0 20.3 8.49 23.8 47.5 29.2
A ♀ 9.73 33.3 16.9 13.2 26.4
B6 ♀ 17.9 24.6 27.9 31.7 20.9 20.2
CAST ♀ 16.7 5.36 10.6 9.95 13.2 7.36
NOD ♀ 18.0 14.8 35.5 34.5
NZO ♀ 51.7 33.2 24.9 0.840 15.8
PWK ♀ 32.2 15.9 7.06 10.1
WSB ♀ 22.8 18.4 12.8 12.1 8.86 18.2

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 41.6 42.5 22.4 31.9 58.9 30.8 18.5
A ♀ 23.1 22.2 26.9 24.3 25.6 20.1 16.9
B6 ♀ 26.6 32.7 31.6 24.7 46.4 18.8 14.9
CAST ♀ 29.1 17.7 9.23 33.0 23.8 12.6 5.99
NOD ♀ 22.5 36.2 41.0 21.6 28.4 36.0 22.9
NZO ♀ 48.3 49.7 33.4
PWK ♀ 16.3 17.4 44.5 24.0
WSB ♀ 22.1 24.3 19.2 20.8 26.6 11.9

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested42 strains48 strains
Mean of the strain means20.0   % 27.1   %
Median of the strain means17.9   % 24.3   %
SD of the strain means± 11.0 ± 11.2
Coefficient of variation (CV)0.552 0.413
Min–max range of strain means0.840   –   51.7   % 5.99   –   58.9   %
Mean sample size per strain2.1   mice 2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1428.4794 1428.4794 16.066 0.0001
strain 13 8160.7401 627.7492 7.0602 < 0.0001
sex:strain 13 3632.8473 279.4498 3.143 0.0009
Residuals 75 6668.4886 88.9132


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 41.6 0.0   1   0.0 0.0 41.6, 41.6 1.3
129SAF1 f 16.0 8.23   3 4.75 0.513 9.86, 25.4 -0.36
129SAF1 m 42.5 18.2   5 8.12 0.427 12.9, 57.4 1.38
129SB6F1 f 20.3 8.03   2   5.68 0.396 14.6, 26.0 0.03
129SB6F1 m 22.4 10.4   5 4.63 0.463 12.1, 38.3 -0.42
129SCASTF1 f 8.49 0.0   1   0.0 0.0 8.49, 8.49 -1.04
129SCASTF1 m 31.9 0.0   1   0.0 0.0 31.9, 31.9 0.43
129SNODF1 f 23.8 0.0   1   0.0 0.0 23.8, 23.8 0.35
129SNZOF1 f 47.5 0.0   1   0.0 0.0 47.5, 47.5 2.5
129SNZOF1 m 58.9 11.2   3 6.44 0.19 47.1, 69.3 2.85
129SPWKF1 f 29.2 3.43   3 1.98 0.117 25.5, 32.2 0.84
129SPWKF1 m 30.8 0.0   1   0.0 0.0 30.8, 30.8 0.33
129SWSBF1 m 18.5 0.0   1   0.0 0.0 18.5, 18.5 -0.77
AB6F1 f 9.73 0.0   1   0.0 0.0 9.73, 9.73 -0.93
AB6F1 m 22.2 10.3   2   7.27 0.464 14.9, 29.4 -0.44
ACASTF1 f 33.3 4.66   4 2.33 0.14 26.6, 37.5 1.21
ACASTF1 m 26.9 12.4   4 6.18 0.459 19.1, 45.2 -0.02
A/J m 23.1 3.4   3 1.96 0.147 19.8, 26.6 -0.36
ANODF1 f 16.9 0.0   1   0.0 0.0 16.9, 16.9 -0.28
ANODF1 m 24.3 10.1   6 4.13 0.416 11.1, 39.0 -0.25
ANZOF1 f 13.2 0.0   1   0.0 0.0 13.2, 13.2 -0.61
ANZOF1 m 25.6 0.0   1   0.0 0.0 25.6, 25.6 -0.13
APWKF1 f 26.4 7.1   3 4.1 0.269 18.2, 30.7 0.58
APWKF1 m 20.1 4.71   4 2.35 0.234 15.1, 26.4 -0.62
AWSBF1 m 16.9 0.0   1   0.0 0.0 16.9, 16.9 -0.91
B6129SF1/J f 17.9 0.467   2   0.33 0.0261 17.6, 18.2 -0.19
B6129SF1/J m 26.6 3.07   3 1.77 0.116 23.2, 29.2 -0.04
B6AF1/J f 24.6 9.14   2   6.46 0.372 18.1, 31.0 0.42
B6AF1/J m 32.7 5.18   2   3.66 0.158 29.0, 36.4 0.5
B6CASTF1 m 24.7 0.0   1   0.0 0.0 24.7, 24.7 -0.21
B6NODF1 f 27.9 0.0   1   0.0 0.0 27.9, 27.9 0.72
B6NODF1 m 46.4 0.0   1   0.0 0.0 46.4, 46.4 1.73
B6NZOF1 f 31.7 8.38   2   5.93 0.264 25.8, 37.6 1.06
B6NZOF1 m 18.8 0.0   1   0.0 0.0 18.8, 18.8 -0.74
B6PWKF1 f 20.9 1.86   2   1.31 0.0891 19.6, 22.2 0.08
B6WSBF1 f 20.2 6.95   5 3.11 0.343 9.05, 26.6 0.02
B6WSBF1 m 14.9 0.0   1   0.0 0.0 14.9, 14.9 -1.09
C57BL/6J m 31.6 5.92   3 3.42 0.187 25.7, 37.5 0.4
CAST129SF1 m 29.1 11.7   5 5.23 0.402 11.8, 42.7 0.18
CASTAF1 f 16.7 0.0   1   0.0 0.0 16.7, 16.7 -0.3
CASTB6F1 f 5.36 0.0   1   0.0 0.0 5.36, 5.36 -1.33
CASTB6F1 m 17.7 5.55   3 3.21 0.314 11.9, 22.9 -0.84
CAST/EiJ f 10.6 4.45   3 2.57 0.418 6.7, 15.5 -0.85
CAST/EiJ m 9.23 5.06   2   3.57 0.548 5.65, 12.8 -1.6
CASTNODF1 m 33.0 7.9   6 3.23 0.24 21.7, 42.8 0.53
CASTNZOF1 f 9.95 5.64   2   3.99 0.567 5.96, 13.9 -0.91
CASTNZOF1 m 23.8 0.0   1   0.0 0.0 23.8, 23.8 -0.29
CASTPWKF1 f 13.2 3.82   5 1.71 0.29 7.86, 18.1 -0.61
CASTPWKF1 m 12.6 5.28   6 2.16 0.418 6.32, 19.9 -1.3
CASTWSBF1 f 7.36 0.0   1   0.0 0.0 7.36, 7.36 -1.14
CASTWSBF1 m 5.99 0.0   1   0.0 0.0 5.99, 5.99 -1.89
NOD129SF1 f 18.0 0.0   1   0.0 0.0 18.0, 18.0 -0.18
NOD129SF1 m 22.5 0.0   1   0.0 0.0 22.5, 22.5 -0.41
NODAF1 f 14.8 0.0   1   0.0 0.0 14.8, 14.8 -0.47
NODAF1 m 36.2 0.0   1   0.0 0.0 36.2, 36.2 0.82
NODB6F1 m 41.0 18.6   2   13.1 0.453 27.9, 54.1 1.25
NODCASTF1 m 21.6 0.665   2   0.47 0.0308 21.1, 22.1 -0.49
NODNZOF1 f 35.5 8.78   2   6.21 0.248 29.3, 41.7 1.41
NODNZOF1 m 36.0 12.6   3 7.28 0.351 22.4, 47.4 0.8
NODPWKF1 f 34.5 8.97   2   6.35 0.26 28.2, 40.9 1.32
NODPWKF1 m 22.9 8.95   8 3.16 0.392 8.39, 37.8 -0.37
NOD/ShiLtJ m 28.4 0.0   1   0.0 0.0 28.4, 28.4 0.12
NZO129SF1 f 51.7 0.0   1   0.0 0.0 51.7, 51.7 2.88
NZO129SF1 m 48.3 0.0   1   0.0 0.0 48.3, 48.3 1.9
NZOAF1 f 33.2 0.0   1   0.0 0.0 33.2, 33.2 1.2
NZOB6F1 f 24.9 13.7   5 6.15 0.551 12.7, 47.5 0.45
NZOB6F1 m 49.7 11.2   8 3.94 0.224 23.8, 58.2 2.02
NZO/HlLtJ m 33.4 0.0   1   0.0 0.0 33.4, 33.4 0.57
NZONODF1 f 0.84 0.0   1   0.0 0.0 0.84, 0.84 -1.74
NZOWSBF1 f 15.8 10.4   3 5.99 0.655 7.41, 27.4 -0.38
PWK129SF1 f 32.2 1.88   2   1.33 0.0585 30.8, 33.5 1.11
PWKAF1 f 15.9 6.33   2   4.47 0.398 11.4, 20.4 -0.37
PWKAF1 m 16.3 0.0   1   0.0 0.0 16.3, 16.3 -0.96
PWKB6F1 m 17.4 0.0   1   0.0 0.0 17.4, 17.4 -0.87
PWKNODF1 f 7.06 0.0   1   0.0 0.0 7.06, 7.06 -1.17
PWKNODF1 m 44.5 0.0   1   0.0 0.0 44.5, 44.5 1.56
PWK/PhJ f 10.1 9.3   4 4.65 0.925 0.75, 22.2 -0.9
PWK/PhJ m 24.0 1.84   3 1.06 0.0764 22.6, 26.1 -0.28
WSB129SF1 f 22.8 4.93   2   3.49 0.217 19.3, 26.2 0.26
WSBAF1 f 18.4 0.0   1   0.0 0.0 18.4, 18.4 -0.14
WSBAF1 m 22.1 1.58   2   1.12 0.0718 20.9, 23.2 -0.45
WSBB6F1 m 24.3 7.9   2   5.59 0.324 18.8, 29.9 -0.25
WSBCASTF1 m 19.2 5.79   5 2.59 0.302 11.8, 27.2 -0.71
WSB/EiJ f 18.2 13.1   3 7.56 0.717 4.58, 30.7 -0.16
WSB/EiJ m 11.9 9.08   3 5.24 0.764 4.91, 22.1 -1.36
WSBNODF1 f 12.8 0.0   1   0.0 0.0 12.8, 12.8 -0.65
WSBNODF1 m 20.8 9.39   2   6.64 0.452 14.2, 27.4 -0.56
WSBNZOF1 f 12.1 7.01   5 3.14 0.577 3.77, 23.2 -0.71
WSBNZOF1 m 26.6 2.35   2   1.66 0.0884 25.0, 28.3 -0.04
WSBPWKF1 f 8.86 6.81   3 3.93 0.769 1.7, 15.3 -1.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f 16.0367 5.4441 26.8818 5.1916
129SAF1 m 42.528 4.2169 50.9286 34.1274
129SB6F1 f 20.29 6.6676 33.5725 7.0075
129SB6F1 m 22.354 4.2169 30.7546 13.9534
ACASTF1 f 33.33 4.7147 42.7221 23.9379
ACASTF1 m 26.9075 4.7147 36.2996 17.5154
APWKF1 f 26.44 5.4441 37.2851 15.5949
APWKF1 m 20.0825 4.7147 29.4746 10.6904
B6129SF1/J f 17.89 6.6676 31.1725 4.6075
B6129SF1/J m 26.55 5.4441 37.3951 15.7049
B6AF1/J f 24.55 6.6676 37.8325 11.2675
B6AF1/J m 32.69 6.6676 45.9725 19.4075
CAST/EiJ f 10.6367 5.4441 21.4818 0.0
CAST/EiJ m 9.225 6.6676 22.5075 0.0
CASTPWKF1 f 13.152 4.2169 21.5526 4.7514
CASTPWKF1 m 12.64 3.8495 20.3087 4.9713
NODNZOF1 f 35.47 6.6676 48.7525 22.1875
NODNZOF1 m 35.9667 5.4441 46.8118 25.1216
NODPWKF1 f 34.525 6.6676 47.8075 21.2425
NODPWKF1 m 22.85 3.3338 29.4912 16.2088
NZOB6F1 f 24.938 4.2169 33.3386 16.5374
NZOB6F1 m 49.69 3.3338 56.3312 43.0488
PWK/PhJ f 10.055 4.7147 19.4471 0.6629
PWK/PhJ m 24.04 5.4441 34.8851 13.1949
WSB/EiJ f 18.2433 5.4441 29.0884 7.3982
WSB/EiJ m 11.8867 5.4441 22.7318 1.0416
WSBNZOF1 f 12.146 4.2169 20.5466 3.7454
WSBNZOF1 m 26.625 6.6676 39.9075 13.3425


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 29.2823 3.4431 36.1414 22.4233
129SB6F1 both 21.322 3.9446 29.18 13.464
ACASTF1 both 30.1187 3.3338 36.76 23.4775
APWKF1 both 23.2613 3.6009 30.4346 16.0879
B6129SF1/J both 22.22 4.3039 30.7938 13.6462
B6AF1/J both 28.62 4.7147 38.0121 19.2279
CAST/EiJ both 9.9308 4.3039 18.5046 1.357
CASTPWKF1 both 12.896 2.8549 18.5832 7.2088
NODNZOF1 both 35.7183 4.3039 44.2921 27.1445
NODPWKF1 both 28.6875 3.7273 36.1126 21.2624
NZOB6F1 both 37.314 2.6878 42.6683 31.9597
PWK/PhJ both 17.0475 3.6009 24.2209 9.8741
WSB/EiJ both 15.065 3.8495 22.7337 7.3963
WSBNZOF1 both 19.3855 3.9446 27.2435 11.5275




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA