Phenotype measure:   Chesler2   pct_daily_deprivation

ID, description, units MPD:43483   pct_daily_deprivation   percentage of time spent sleeping, following sleep deprivation   [%]
Data set, strains Chesler2   CC diallel w/par   48 strains     sex: both     age: 7-15wks
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  STRAIN COMPARISON PLOT
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Chesler2 - percentage of time spent sleeping, following sleep deprivation



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 25.6 27.4 13.8 33.6 45.1 33.6
A ♀ 18.8 40.1 30.8 26.9 32.9
B6 ♀ 30.8 30.2 34.7 37.3 27.8 29.5
CAST ♀ 23.3 9.31 20.4 20.3 22.8 20.6
NOD ♀ 26.9 25.6 38.6 40.5
NZO ♀ 49.9 41.3 34.8 6.47 20.5
PWK ♀ 38.8 25.8 20.5 17.9
WSB ♀ 32.1 16.2 20.6 21.7 20.2 27.2

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 50.0 45.5 29.9 32.7 57.0 29.2 20.9
A ♀ 31.5 32.5 34.3 32.5 27.5 28.6 23.2
B6 ♀ 36.4 34.3 38.2 26.4 39.9 15.4 27.3
CAST ♀ 33.6 25.7 17.0 38.8 30.2 21.1 11.9
NOD ♀ 22.5 37.9 39.6 27.9 40.3 40.1 31.6
NZO ♀ 47.1 45.4 43.4
PWK ♀ 27.3 20.2 45.6 36.2
WSB ♀ 29.3 31.4 25.2 30.1 32.4 21.6

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested42 strains48 strains
Mean of the strain means27.6   % 32.2   %
Median of the strain means27.0   % 31.6   %
SD of the strain means± 9.41 ± 9.31
Coefficient of variation (CV)0.340 0.289
Min–max range of strain means6.47   –   49.9   % 11.9   –   57.0   %
Mean sample size per strain2.1   mice 2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 634.8979 634.8979 12.6405 0.0007
strain 13 4591.5574 353.1967 7.0319 < 0.0001
sex:strain 13 1894.9903 145.7685 2.9022 0.0019
Residuals 75 3767.0597 50.2275


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 50.0 0.0   1   0.0 0.0 50.0, 50.0 1.91
129SAF1 f 25.6 9.64   3 5.57 0.376 20.0, 36.8 -0.22
129SAF1 m 45.5 10.4   5 4.63 0.228 29.1, 55.9 1.43
129SB6F1 f 27.4 7.66   2   5.42 0.28 22.0, 32.8 -0.03
129SB6F1 m 29.9 7.79   5 3.48 0.261 24.0, 43.1 -0.25
129SCASTF1 f 13.8 0.0   1   0.0 0.0 13.8, 13.8 -1.47
129SCASTF1 m 32.7 0.0   1   0.0 0.0 32.7, 32.7 0.05
129SNODF1 f 33.6 0.0   1   0.0 0.0 33.6, 33.6 0.63
129SNZOF1 f 45.1 0.0   1   0.0 0.0 45.1, 45.1 1.86
129SNZOF1 m 57.0 5.8   3 3.35 0.102 50.3, 60.4 2.66
129SPWKF1 f 33.6 3.83   3 2.21 0.114 30.1, 37.7 0.63
129SPWKF1 m 29.2 0.0   1   0.0 0.0 29.2, 29.2 -0.32
129SWSBF1 m 20.9 0.0   1   0.0 0.0 20.9, 20.9 -1.22
AB6F1 f 18.8 0.0   1   0.0 0.0 18.8, 18.8 -0.94
AB6F1 m 32.5 6.13   2   4.33 0.188 28.2, 36.9 0.03
ACASTF1 f 40.1 2.09   4 1.05 0.0522 38.2, 43.1 1.32
ACASTF1 m 34.3 7.56   4 3.78 0.221 28.6, 45.3 0.22
A/J m 31.5 4.21   3 2.43 0.133 29.1, 36.4 -0.08
ANODF1 f 30.8 0.0   1   0.0 0.0 30.8, 30.8 0.34
ANODF1 m 32.5 6.82   6 2.78 0.21 23.6, 41.8 0.03
ANZOF1 f 26.9 0.0   1   0.0 0.0 26.9, 26.9 -0.08
ANZOF1 m 27.5 0.0   1   0.0 0.0 27.5, 27.5 -0.51
APWKF1 f 32.9 8.11   3 4.68 0.247 24.1, 40.1 0.56
APWKF1 m 28.6 3.38   4 1.69 0.118 24.2, 31.6 -0.39
AWSBF1 m 23.2 0.0   1   0.0 0.0 23.2, 23.2 -0.97
B6129SF1/J f 30.8 1.17   2   0.825 0.0379 30.0, 31.6 0.34
B6129SF1/J m 36.4 0.998   3 0.576 0.0274 35.7, 37.6 0.45
B6AF1/J f 30.2 2.96   2   2.09 0.0978 28.1, 32.3 0.27
B6AF1/J m 34.3 3.71   2   2.62 0.108 31.7, 36.9 0.22
B6CASTF1 m 26.4 0.0   1   0.0 0.0 26.4, 26.4 -0.63
B6NODF1 f 34.7 0.0   1   0.0 0.0 34.7, 34.7 0.75
B6NODF1 m 39.9 0.0   1   0.0 0.0 39.9, 39.9 0.82
B6NZOF1 f 37.3 4.78   2   3.38 0.128 33.9, 40.6 1.03
B6NZOF1 m 15.4 0.0   1   0.0 0.0 15.4, 15.4 -1.81
B6PWKF1 f 27.8 1.7   2   1.21 0.0613 26.6, 29.0 0.02
B6WSBF1 f 29.5 14.5   5 6.47 0.491 4.53, 40.8 0.2
B6WSBF1 m 27.3 0.0   1   0.0 0.0 27.3, 27.3 -0.53
C57BL/6J m 38.2 4.3   3 2.48 0.113 34.0, 42.6 0.64
CAST129SF1 m 33.6 8.6   5 3.85 0.256 19.3, 41.0 0.15
CASTAF1 f 23.3 0.0   1   0.0 0.0 23.3, 23.3 -0.46
CASTB6F1 f 9.31 0.0   1   0.0 0.0 9.31, 9.31 -1.95
CASTB6F1 m 25.7 6.63   3 3.82 0.258 19.1, 32.4 -0.7
CAST/EiJ f 20.4 3.76   3 2.17 0.184 18.2, 24.8 -0.77
CAST/EiJ m 17.0 5.14   2   3.63 0.302 13.4, 20.7 -1.63
CASTNODF1 m 38.8 7.46   6 3.04 0.192 25.3, 45.5 0.71
CASTNZOF1 f 20.3 3.28   2   2.32 0.161 18.0, 22.6 -0.78
CASTNZOF1 m 30.2 0.0   1   0.0 0.0 30.2, 30.2 -0.22
CASTPWKF1 f 22.8 4.73   5 2.11 0.207 19.2, 30.9 -0.52
CASTPWKF1 m 21.1 5.44   6 2.22 0.258 15.2, 29.5 -1.19
CASTWSBF1 f 20.6 0.0   1   0.0 0.0 20.6, 20.6 -0.75
CASTWSBF1 m 11.9 0.0   1   0.0 0.0 11.9, 11.9 -2.18
NOD129SF1 f 26.9 0.0   1   0.0 0.0 26.9, 26.9 -0.08
NOD129SF1 m 22.5 0.0   1   0.0 0.0 22.5, 22.5 -1.04
NODAF1 f 25.6 0.0   1   0.0 0.0 25.6, 25.6 -0.22
NODAF1 m 37.9 0.0   1   0.0 0.0 37.9, 37.9 0.61
NODB6F1 m 39.6 8.29   2   5.86 0.21 33.7, 45.4 0.79
NODCASTF1 m 27.9 3.77   2   2.66 0.135 25.2, 30.5 -0.46
NODNZOF1 f 38.6 10.2   2   7.23 0.265 31.4, 45.9 1.16
NODNZOF1 m 40.1 9.95   3 5.74 0.248 29.1, 48.3 0.85
NODPWKF1 f 40.5 5.97   2   4.22 0.147 36.3, 44.7 1.37
NODPWKF1 m 31.6 7.74   8 2.74 0.245 19.7, 43.0 -0.07
NOD/ShiLtJ m 40.3 0.0   1   0.0 0.0 40.3, 40.3 0.87
NZO129SF1 f 49.9 0.0   1   0.0 0.0 49.9, 49.9 2.37
NZO129SF1 m 47.1 0.0   1   0.0 0.0 47.1, 47.1 1.6
NZOAF1 f 41.3 0.0   1   0.0 0.0 41.3, 41.3 1.45
NZOB6F1 f 34.8 8.59   5 3.84 0.247 26.1, 48.4 0.76
NZOB6F1 m 45.4 7.14   8 2.52 0.157 28.8, 50.8 1.42
NZO/HlLtJ m 43.4 0.0   1   0.0 0.0 43.4, 43.4 1.2
NZONODF1 f 6.47 0.0   1   0.0 0.0 6.47, 6.47 -2.25
NZOWSBF1 f 20.5 12.0   3 6.9 0.583 11.7, 34.1 -0.76
PWK129SF1 f 38.8 2.7   2   1.91 0.0696 36.9, 40.7 1.19
PWKAF1 f 25.8 0.339   2   0.24 0.0132 25.5, 26.0 -0.2
PWKAF1 m 27.3 0.0   1   0.0 0.0 27.3, 27.3 -0.53
PWKB6F1 m 20.2 0.0   1   0.0 0.0 20.2, 20.2 -1.29
PWKNODF1 f 20.5 0.0   1   0.0 0.0 20.5, 20.5 -0.76
PWKNODF1 m 45.6 0.0   1   0.0 0.0 45.6, 45.6 1.44
PWK/PhJ f 17.9 11.6   4 5.79 0.647 0.89, 26.5 -1.04
PWK/PhJ m 36.2 4.73   3 2.73 0.131 31.2, 40.6 0.43
WSB129SF1 f 32.1 8.22   2   5.81 0.256 26.3, 37.9 0.47
WSBAF1 f 16.2 0.0   1   0.0 0.0 16.2, 16.2 -1.22
WSBAF1 m 29.3 0.0212   2   0.015 0.000725 29.2, 29.3 -0.31
WSBB6F1 m 31.4 10.6   2   7.48 0.337 23.9, 38.9 -0.09
WSBCASTF1 m 25.2 5.23   5 2.34 0.207 19.3, 33.2 -0.75
WSB/EiJ f 27.2 8.93   3 5.15 0.329 16.9, 33.4 -0.05
WSB/EiJ m 21.6 5.09   3 2.94 0.235 18.2, 27.5 -1.14
WSBNODF1 f 20.6 0.0   1   0.0 0.0 20.6, 20.6 -0.75
WSBNODF1 m 30.1 3.82   2   2.7 0.127 27.4, 32.8 -0.23
WSBNZOF1 f 21.7 5.34   5 2.39 0.247 15.3, 29.3 -0.63
WSBNZOF1 m 32.4 0.651   2   0.46 0.0201 32.0, 32.9 0.02
WSBPWKF1 f 20.2 4.26   3 2.46 0.211 16.2, 24.7 -0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f 25.6233 4.0918 33.7745 17.4721
129SAF1 m 45.496 3.1695 51.8099 39.1821
129SB6F1 f 27.385 5.0114 37.3681 17.4019
129SB6F1 m 29.87 3.1695 36.1839 23.5561
ACASTF1 f 40.09 3.5436 47.1491 33.0309
ACASTF1 m 34.295 3.5436 41.3541 27.2359
APWKF1 f 32.8833 4.0918 41.0345 24.7321
APWKF1 m 28.6475 3.5436 35.7066 21.5884
B6129SF1/J f 30.795 5.0114 40.7781 20.8119
B6129SF1/J m 36.4333 4.0918 44.5845 28.2821
B6AF1/J f 30.22 5.0114 40.2031 20.2369
B6AF1/J m 34.305 5.0114 44.2881 24.3219
CAST/EiJ f 20.41 4.0918 28.5612 12.2588
CAST/EiJ m 17.035 5.0114 27.0181 7.0519
CASTPWKF1 f 22.814 3.1695 29.1279 16.5001
CASTPWKF1 m 21.1133 2.8933 26.8771 15.3496
NODNZOF1 f 38.645 5.0114 48.6281 28.6619
NODNZOF1 m 40.1467 4.0918 48.2979 31.9955
NODPWKF1 f 40.48 5.0114 50.4631 30.4969
NODPWKF1 m 31.5862 2.5057 36.5778 26.5947
NZOB6F1 f 34.754 3.1695 41.0679 28.4401
NZOB6F1 m 45.395 2.5057 50.3866 40.4034
PWK/PhJ f 17.8925 3.5436 24.9516 10.8334
PWK/PhJ m 36.1667 4.0918 44.3179 28.0155
WSB/EiJ f 27.16 4.0918 35.3112 19.0088
WSB/EiJ m 21.6367 4.0918 29.7879 13.4855
WSBNZOF1 f 21.654 3.1695 27.9679 15.3401
WSBNZOF1 m 32.42 5.0114 42.4031 22.4369


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 35.5597 2.5879 40.7149 30.4044
129SB6F1 both 28.6275 2.9648 34.5336 22.7214
ACASTF1 both 37.1925 2.5057 42.1841 32.2009
APWKF1 both 30.7654 2.7064 36.1569 25.3739
B6129SF1/J both 33.6142 3.2348 40.0583 27.1701
B6AF1/J both 32.2625 3.5436 39.3216 25.2034
CAST/EiJ both 18.7225 3.2348 25.1666 12.2784
CASTPWKF1 both 21.9637 2.1457 26.2382 17.6891
NODNZOF1 both 39.3958 3.2348 45.8399 32.9517
NODPWKF1 both 36.0331 2.8014 41.6139 30.4524
NZOB6F1 both 40.0745 2.0201 44.0988 36.0502
PWK/PhJ both 27.0296 2.7064 32.4211 21.6381
WSB/EiJ both 24.3983 2.8933 30.1621 18.6346
WSBNZOF1 both 27.037 2.9648 32.9431 21.1309




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA