Phenotype measure:   Chesler2   pct_sleep_dark

ID, description, units MPD:43482   pct_sleep_dark   percentage of time spent sleeping during dark period, baseline   [%]
Data set, strains Chesler2   CC diallel w/par   51 strains     sex: both     age: 7-15wks
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Ontology mappings

  STRAIN COMPARISON PLOT
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Chesler2 - percentage of time spent sleeping during dark period, baseline



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 17.4 20.7 13.5 17.4 40.6 27.8
A ♀ 16.5 27.5 16.6 27.6 22.6
B6 ♀ 22.1 17.4 22.1 24.3 17.6 16.5
CAST ♀ 8.52 8.18 9.98 13.8 13.4 20.7
NOD ♀ 16.0 19.1 19.0 26.7 31.3
NZO ♀ 49.8 39.8 24.2 27.4 19.1
PWK ♀ 19.8 9.79 12.2 11.6
WSB ♀ 22.5 17.5 14.3 10.2 20.0 17.0 19.3

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 42.7 37.6 29.5 24.1 24.7 54.5 15.2 16.3
A ♀ 22.7 25.8 25.0 21.7 46.5 20.6 17.5
B6 ♀ 25.9 29.6 26.2 17.3 33.2 15.2 20.1
CAST ♀ 23.6 20.9 11.2 11.5 30.6 25.7 11.8 10.6
NOD ♀ 24.0 25.3 28.9 23.1 33.4 29.2 23.6
NZO ♀ 53.8 48.8 29.0 41.4
PWK ♀ 14.6 23.1 29.0 25.5
WSB ♀ 17.8 22.3 16.0 17.3 16.2 12.5

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested44 strains51 strains
Mean of the strain means20.2   % 25.3   %
Median of the strain means19.1   % 24.0   %
SD of the strain means± 8.52 ± 10.5
Coefficient of variation (CV)0.421 0.414
Min–max range of strain means8.18   –   49.8   % 10.6   –   54.5   %
Mean sample size per strain3.0   mice 3.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2069.7802 2069.7802 31.7013 < 0.0001
strain 20 7135.3955 356.7698 5.4644 < 0.0001
sex:strain 20 3272.6102 163.6305 2.5062 0.0009
Residuals 147 9597.6425 65.2901


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 42.7 0.0   1   0.0 0.0 42.7, 42.7 1.65
129SAF1 f 17.4 3.29   3 1.9 0.189 13.8, 20.1 -0.33
129SAF1 m 37.6 13.7   6 5.61 0.365 14.4, 49.9 1.17
129SB6F1 f 20.7 6.28   6 2.56 0.303 13.0, 29.9 0.06
129SB6F1 m 29.5 10.1   5 4.51 0.342 18.4, 43.7 0.4
129SCASTF1 f 13.5 2.41   2   1.71 0.178 11.8, 15.2 -0.79
129SCASTF1 m 24.1 0.0   1   0.0 0.0 24.1, 24.1 -0.12
129SNODF1 f 17.4 6.86   8 2.43 0.395 11.6, 31.4 -0.33
129SNODF1 m 24.7 9.84   3 5.68 0.398 17.7, 36.0 -0.06
129SNZOF1 f 40.6 0.0   1   0.0 0.0 40.6, 40.6 2.39
129SNZOF1 m 54.5 10.6   5 4.75 0.195 36.6, 62.4 2.78
129SPWKF1 f 27.8 5.99   3 3.46 0.215 21.0, 32.3 0.89
129SPWKF1 m 15.2 0.0   1   0.0 0.0 15.2, 15.2 -0.97
129SWSBF1 m 16.3 0.0   1   0.0 0.0 16.3, 16.3 -0.86
AB6F1 f 16.5 7.08   4 3.54 0.43 9.33, 25.8 -0.44
AB6F1 m 25.8 5.93   6 2.42 0.23 15.2, 31.2 0.04
ACASTF1 f 27.5 6.57   4 3.29 0.239 19.1, 33.3 0.86
ACASTF1 m 25.0 7.3   4 3.65 0.292 18.1, 35.1 -0.03
A/J m 22.7 3.61   3 2.08 0.159 18.7, 25.8 -0.25
ANODF1 f 16.6 0.0   1   0.0 0.0 16.6, 16.6 -0.42
ANODF1 m 21.7 9.51   7 3.59 0.438 11.2, 36.3 -0.35
ANZOF1 f 27.6 0.0   1   0.0 0.0 27.6, 27.6 0.87
ANZOF1 m 46.5 0.0   1   0.0 0.0 46.5, 46.5 2.02
APWKF1 f 22.6 7.49   3 4.32 0.331 14.4, 29.0 0.28
APWKF1 m 20.6 8.79   5 3.93 0.427 12.2, 35.5 -0.45
AWSBF1 m 17.5 0.0   1   0.0 0.0 17.5, 17.5 -0.75
B6129SF1/J f 22.1 5.66   6 2.31 0.257 16.8, 32.5 0.22
B6129SF1/J m 25.9 8.58   11 2.59 0.332 11.7, 37.4 0.05
B6AF1/J f 17.4 6.3   5 2.82 0.362 10.3, 27.5 -0.33
B6AF1/J m 29.6 7.22   4 3.61 0.244 21.0, 38.2 0.41
B6CASTF1 m 17.3 0.0   1   0.0 0.0 17.3, 17.3 -0.77
B6NODF1 f 22.1 15.8   2   11.2 0.715 10.9, 33.3 0.22
B6NODF1 m 33.2 13.8   2   9.73 0.415 23.4, 42.9 0.75
B6NZOF1 f 24.3 11.9   3 6.89 0.491 11.7, 35.4 0.48
B6NZOF1 m 15.2 13.6   2   9.61 0.897 5.55, 24.8 -0.97
B6PWKF1 f 17.6 5.36   2   3.79 0.305 13.8, 21.4 -0.31
B6WSBF1 f 16.5 5.69   8 2.01 0.345 5.97, 25.3 -0.44
B6WSBF1 m 20.1 4.46   3 2.58 0.222 16.7, 25.2 -0.5
C57BL/6J m 26.2 9.42   3 5.44 0.36 17.3, 36.0 0.08
CAST129SF1 m 23.6 11.2   6 4.59 0.476 7.66, 35.7 -0.17
CASTAF1 f 8.52 0.0   1   0.0 0.0 8.52, 8.52 -1.37
CASTAF1 m 20.9 0.0   1   0.0 0.0 20.9, 20.9 -0.42
CASTB6F1 f 8.18 0.0   1   0.0 0.0 8.18, 8.18 -1.41
CASTB6F1 m 11.2 1.05   3 0.608 0.0939 10.0, 12.0 -1.35
CAST/EiJ f 9.98 0.665   3 0.384 0.0666 9.33, 10.7 -1.2
CAST/EiJ m 11.5 2.02   2   1.42 0.175 10.1, 12.9 -1.32
CASTNODF1 m 30.6 6.07   6 2.48 0.198 24.1, 40.8 0.5
CASTNZOF1 f 13.8 1.75   3 1.01 0.126 12.8, 15.9 -0.75
CASTNZOF1 m 25.7 0.0   1   0.0 0.0 25.7, 25.7 0.03
CASTPWKF1 f 13.4 2.91   5 1.3 0.217 10.1, 18.0 -0.8
CASTPWKF1 m 11.8 4.19   6 1.71 0.355 8.87, 18.5 -1.29
CASTWSBF1 f 20.7 0.0   1   0.0 0.0 20.7, 20.7 0.06
CASTWSBF1 m 10.6 0.0   1   0.0 0.0 10.6, 10.6 -1.4
NOD129SF1 f 16.0 0.0   1   0.0 0.0 16.0, 16.0 -0.49
NOD129SF1 m 24.0 0.0   1   0.0 0.0 24.0, 24.0 -0.13
NODAF1 f 19.1 15.3   3 8.84 0.8 5.91, 35.9 -0.13
NODAF1 m 25.3 12.4   4 6.21 0.49 9.03, 38.9 0.0
NODB6F1 f 19.0 0.0   1   0.0 0.0 19.0, 19.0 -0.14
NODB6F1 m 28.9 4.0   2   2.83 0.138 26.0, 31.7 0.34
NODCASTF1 m 23.1 4.13   2   2.92 0.179 20.2, 26.0 -0.21
NODNZOF1 f 26.7 8.1   6 3.31 0.303 17.6, 38.3 0.76
NODNZOF1 m 29.2 12.8   8 4.52 0.437 15.3, 54.8 0.37
NODPWKF1 f 31.3 2.64   2   1.87 0.0844 29.4, 33.2 1.3
NODPWKF1 m 23.6 6.33   8 2.24 0.268 11.8, 34.9 -0.17
NOD/ShiLtJ m 33.4 0.0   1   0.0 0.0 33.4, 33.4 0.77
NZO129SF1 f 49.8 0.0   1   0.0 0.0 49.8, 49.8 3.47
NZO129SF1 m 53.8 0.0   1   0.0 0.0 53.8, 53.8 2.71
NZOAF1 f 39.8 0.0   1   0.0 0.0 39.8, 39.8 2.3
NZOB6F1 f 24.2 8.65   5 3.87 0.357 16.0, 38.6 0.47
NZOB6F1 m 48.8 7.69   8 2.72 0.158 39.2, 63.4 2.23
NZO/HlLtJ m 41.4 0.0   1   0.0 0.0 41.4, 41.4 1.53
NZONODF1 f 27.4 0.0   1   0.0 0.0 27.4, 27.4 0.84
NZONODF1 m 29.0 0.0   1   0.0 0.0 29.0, 29.0 0.35
NZOWSBF1 f 19.1 6.73   3 3.88 0.353 12.0, 25.4 -0.13
PWK129SF1 f 19.8 7.98   8 2.82 0.402 9.26, 31.1 -0.05
PWKAF1 f 9.79 0.0495   2   0.035 0.00506 9.75, 9.82 -1.22
PWKAF1 m 14.6 0.0   1   0.0 0.0 14.6, 14.6 -1.02
PWKB6F1 m 23.1 0.0   1   0.0 0.0 23.1, 23.1 -0.21
PWKNODF1 f 12.2 0.0   1   0.0 0.0 12.2, 12.2 -0.94
PWKNODF1 m 29.0 0.0   1   0.0 0.0 29.0, 29.0 0.35
PWK/PhJ f 11.6 4.19   4 2.09 0.361 6.77, 17.0 -1.01
PWK/PhJ m 25.5 2.12   3 1.23 0.0831 23.7, 27.9 0.01
WSB129SF1 f 22.5 2.26   2   1.6 0.101 20.9, 24.1 0.27
WSBAF1 f 17.5 2.23   2   1.57 0.127 15.9, 19.1 -0.32
WSBAF1 m 17.8 0.693   2   0.49 0.0389 17.3, 18.3 -0.72
WSBB6F1 f 14.3 0.0   1   0.0 0.0 14.3, 14.3 -0.69
WSBB6F1 m 22.3 2.43   3 1.41 0.109 20.1, 24.9 -0.29
WSBCASTF1 m 16.0 3.28   5 1.47 0.204 11.7, 20.0 -0.89
WSB/EiJ f 19.3 6.97   3 4.02 0.362 13.4, 27.0 -0.11
WSB/EiJ m 12.5 5.5   3 3.18 0.439 9.16, 18.9 -1.22
WSBNODF1 f 10.2 0.0   1   0.0 0.0 10.2, 10.2 -1.18
WSBNODF1 m 17.3 6.24   2   4.41 0.361 12.9, 21.7 -0.77
WSBNZOF1 f 20.0 7.51   6 3.07 0.376 11.3, 29.9 -0.02
WSBNZOF1 m 16.2 4.62   3 2.67 0.285 11.7, 20.9 -0.87
WSBPWKF1 f 17.0 6.78   3 3.91 0.399 10.5, 24.0 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f 17.4167 4.6651 26.636 8.1973
129SAF1 m 37.6483 3.2987 44.1674 31.1293
129SB6F1 f 20.7417 3.2987 27.2607 14.2226
129SB6F1 m 29.534 3.6136 36.6753 22.3927
129SNODF1 f 17.3738 2.8568 23.0194 11.7281
129SNODF1 m 24.6967 4.6651 33.916 15.4773
AB6F1 f 16.4575 4.0401 24.4417 8.4733
AB6F1 m 25.7783 3.2987 32.2974 19.2593
ACASTF1 f 27.4775 4.0401 35.4617 19.4933
ACASTF1 m 25.0225 4.0401 33.0067 17.0383
APWKF1 f 22.5867 4.6651 31.806 13.3673
APWKF1 m 20.606 3.6136 27.7473 13.4647
B6129SF1/J f 22.0517 3.2987 28.5707 15.5326
B6129SF1/J m 25.8845 2.4363 30.6992 21.0699
B6AF1/J f 17.386 3.6136 24.5273 10.2447
B6AF1/J m 29.57 4.0401 37.5542 21.5858
B6NODF1 f 22.09 5.7136 33.3814 10.7986
B6NODF1 m 33.175 5.7136 44.4664 21.8836
B6NZOF1 f 24.29 4.6651 33.5094 15.0706
B6NZOF1 m 15.165 5.7136 26.4564 3.8736
B6WSBF1 f 16.5038 2.8568 22.1494 10.8581
B6WSBF1 m 20.1067 4.6651 29.326 10.8873
CAST/EiJ f 9.9833 4.6651 19.2027 0.764
CAST/EiJ m 11.495 5.7136 22.7864 0.2036
CASTPWKF1 f 13.426 3.6136 20.5673 6.2847
CASTPWKF1 m 11.7983 3.2987 18.3174 5.2793
NODAF1 f 19.14 4.6651 28.3594 9.9206
NODAF1 m 25.3425 4.0401 33.3267 17.3583
NODNZOF1 f 26.7433 3.2987 33.2624 20.2243
NODNZOF1 m 29.2287 2.8568 34.8744 23.5831
NODPWKF1 f 31.32 5.7136 42.6114 20.0286
NODPWKF1 m 23.5712 2.8568 29.2169 17.9256
NZOB6F1 f 24.216 3.6136 31.3573 17.0747
NZOB6F1 m 48.76 2.8568 54.4057 43.1143
PWK/PhJ f 11.5875 4.0401 19.5717 3.6033
PWK/PhJ m 25.5367 4.6651 34.756 16.3173
WSBAF1 f 17.475 5.7136 28.7664 6.1836
WSBAF1 m 17.8 5.7136 29.0914 6.5086
WSB/EiJ f 19.26 4.6651 28.4794 10.0406
WSB/EiJ m 12.5133 4.6651 21.7327 3.294
WSBNZOF1 f 19.98 3.2987 26.4991 13.4609
WSBNZOF1 m 16.2333 4.6651 25.4527 7.014


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 27.5325 2.8568 33.1782 21.8868
129SB6F1 both 25.1378 2.4464 29.9725 20.3032
129SNODF1 both 21.0352 2.7352 26.4405 15.6299
AB6F1 both 21.1179 2.6079 26.2717 15.9641
ACASTF1 both 26.25 2.8568 31.8957 20.6043
APWKF1 both 21.5963 2.9505 27.4272 15.7655
B6129SF1/J both 23.9681 2.0504 28.0202 19.916
B6AF1/J both 23.478 2.7102 28.834 18.122
B6NODF1 both 27.6325 4.0401 35.6167 19.6483
B6NZOF1 both 19.7275 3.6881 27.0161 12.4389
B6WSBF1 both 18.3052 2.7352 23.7105 12.8999
CAST/EiJ both 10.7392 3.6881 18.0277 3.4506
CASTPWKF1 both 12.6122 2.4464 17.4468 7.7775
NODAF1 both 22.2412 3.0857 28.3393 16.1432
NODNZOF1 both 27.986 2.1819 32.298 23.6741
NODPWKF1 both 27.4456 3.194 33.7577 21.1336
NZOB6F1 both 36.488 2.3032 41.0397 31.9363
PWK/PhJ both 18.5621 3.0857 24.6601 12.464
WSBAF1 both 17.6375 4.0401 25.6217 9.6533
WSB/EiJ both 15.8867 3.2987 22.4057 9.3676
WSBNZOF1 both 18.1067 2.8568 23.7524 12.461




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA