Phenotype measure:   Chesler2   center10_OFT

ID, description, units MPD:43455   center10_OFT   time spent in center, 10 min test   [s]
Data set, strains Chesler2   CC diallel w/par   41 strains     sex: both     age: 7-15wks
Procedure open field test
Ontology mappings

  STRAIN COMPARISON PLOT
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Chesler2 - time spent in center, 10 min test



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 6.80 6.04 3.59 2.29 3.31 5.50 3.05 3.16
A ♀ 3.40 2.67 1.51
B6 ♀ 3.69 4.01 5.14 4.74 2.73
CAST ♀ 1.87 4.46 2.40 2.02 2.26
NOD ♀ 3.77 2.05 4.68 2.22 4.33 3.63
NZO ♀ 2.94 1.58 6.89 3.70
PWK ♀ 5.16 1.44 3.87
WSB ♀ 4.32 0.860 4.18 3.57 3.76 1.44 2.54

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 4.81 6.42 5.58 3.70 2.99 2.52 2.13
A ♀ 3.89 1.15 4.95 2.19 2.83
B6 ♀ 4.67 3.58 6.16 3.58
CAST ♀ 2.53 2.02 2.80 3.40 3.27 1.35 2.31
NOD ♀ 4.70 4.70 4.76 3.25 4.20
NZO ♀ 3.32 4.63 2.12
PWK ♀ 3.61 3.71 3.06
WSB ♀ 3.03 3.35 2.15 3.63 3.40

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested41 strains39 strains
Mean of the strain means3.45   s 3.50   s
Median of the strain means3.57   s 3.40   s
SD of the strain means± 1.44 ± 1.22
Coefficient of variation (CV)0.418 0.348
Min–max range of strain means0.860   –   6.89   s 1.15   –   6.42   s
Mean sample size per strain2.1   mice 2.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.9899 0.9899 0.4933 0.486
strain 10 112.2329 11.2233 5.5923 < 0.0001
sex:strain 10 28.0419 2.8042 1.3973 0.2118
Residuals 46 92.3175 2.0069


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 6.8 0.0   1   0.0 0.0 6.8, 6.8 2.32
129SAF1 f 6.04 5.03   2   3.55 0.833 2.48, 9.59 1.79
129SAF1 m 4.81 2.53   3 1.46 0.527 1.93, 6.71 1.08
129SB6F1 f 3.59 0.826   3 0.477 0.23 2.7, 4.33 0.09
129SB6F1 m 6.42 0.77   4 0.385 0.12 6.01, 7.57 2.4
129SCASTF1 f 2.29 1.05   2   0.745 0.459 1.55, 3.04 -0.81
129SCASTF1 m 5.58 0.0   1   0.0 0.0 5.58, 5.58 1.71
129SNODF1 f 3.31 0.0   1   0.0 0.0 3.31, 3.31 -0.1
129SNODF1 m 3.7 0.728   2   0.515 0.197 3.18, 4.21 0.17
129SNZOF1 f 5.5 0.0   1   0.0 0.0 5.5, 5.5 1.42
129SNZOF1 m 2.99 0.994   3 0.574 0.332 1.85, 3.65 -0.42
129SPWKF1 f 3.05 0.272   4 0.136 0.0892 2.84, 3.45 -0.28
129SPWKF1 m 2.52 0.0   1   0.0 0.0 2.52, 2.52 -0.8
129SWSBF1 f 3.16 1.21   4 0.605 0.382 2.05, 4.86 -0.2
129SWSBF1 m 2.13 0.629   2   0.445 0.295 1.69, 2.58 -1.12
AB6F1 f 3.4 0.0   1   0.0 0.0 3.4, 3.4 -0.04
AB6F1 m 3.89 1.5   3 0.869 0.386 2.98, 5.63 0.32
ACASTF1 m 1.15 0.0   1   0.0 0.0 1.15, 1.15 -1.93
ANODF1 m 4.95 0.915   5 0.409 0.185 3.91, 5.95 1.19
ANZOF1 f 2.67 1.03   2   0.725 0.385 1.94, 3.39 -0.54
APWKF1 f 1.51 0.0   1   0.0 0.0 1.51, 1.51 -1.35
APWKF1 m 2.19 0.0   1   0.0 0.0 2.19, 2.19 -1.07
AWSBF1 m 2.83 0.0   1   0.0 0.0 2.83, 2.83 -0.55
B6129SF1/J f 3.69 0.346   2   0.245 0.094 3.44, 3.93 0.16
B6AF1/J f 4.01 0.0   1   0.0 0.0 4.01, 4.01 0.39
B6AF1/J m 4.67 2.16   2   1.53 0.463 3.14, 6.2 0.96
B6CASTF1 m 3.58 1.29   2   0.915 0.361 2.67, 4.5 0.07
B6NODF1 f 5.14 0.134   2   0.095 0.0261 5.05, 5.24 1.17
B6NODF1 m 6.16 0.474   2   0.335 0.077 5.82, 6.49 2.18
B6NZOF1 f 4.74 2.65   4 1.33 0.56 2.49, 8.4 0.89
B6NZOF1 m 3.58 0.962   2   0.68 0.269 2.9, 4.26 0.07
B6PWKF1 f 2.73 0.0566   2   0.04 0.0207 2.69, 2.77 -0.5
CAST129SF1 m 2.53 0.843   3 0.487 0.334 2.01, 3.5 -0.8
CASTAF1 f 1.87 0.0   1   0.0 0.0 1.87, 1.87 -1.1
CASTAF1 m 2.02 1.24   2   0.875 0.614 1.14, 2.89 -1.21
CASTB6F1 f 4.46 0.0   1   0.0 0.0 4.46, 4.46 0.7
CASTB6F1 m 2.8 0.769   3 0.444 0.275 2.28, 3.68 -0.57
CASTNODF1 m 3.4 0.682   3 0.394 0.2 2.99, 4.19 -0.08
CASTNZOF1 f 2.4 0.959   3 0.554 0.4 1.29, 2.98 -0.73
CASTNZOF1 m 3.27 0.0   1   0.0 0.0 3.27, 3.27 -0.19
CASTPWKF1 f 2.02 0.63   5 0.282 0.312 1.03, 2.64 -0.99
CASTPWKF1 m 1.35 0.136   6 0.0556 0.101 1.17, 1.49 -1.76
CASTWSBF1 f 2.26 1.03   2   0.73 0.457 1.53, 2.99 -0.83
CASTWSBF1 m 2.31 0.0   1   0.0 0.0 2.31, 2.31 -0.98
NOD129SF1 f 3.77 0.0   1   0.0 0.0 3.77, 3.77 0.22
NOD129SF1 m 4.7 3.45   2   2.44 0.734 2.26, 7.14 0.99
NODAF1 f 2.05 0.0   1   0.0 0.0 2.05, 2.05 -0.97
NODAF1 m 4.7 0.0   1   0.0 0.0 4.7, 4.7 0.99
NODB6F1 f 4.68 0.0   1   0.0 0.0 4.68, 4.68 0.85
NODB6F1 m 4.76 1.16   2   0.82 0.244 3.94, 5.58 1.04
NODCASTF1 f 2.22 0.627   5 0.281 0.283 1.58, 3.06 -0.85
NODCASTF1 m 3.25 0.679   2   0.48 0.209 2.77, 3.73 -0.2
NODNZOF1 f 4.33 0.58   2   0.41 0.134 3.92, 4.74 0.61
NODNZOF1 m 4.2 1.08   3 0.624 0.258 3.41, 5.43 0.58
NODPWKF1 f 3.63 0.0   1   0.0 0.0 3.63, 3.63 0.12
NZO129SF1 f 2.94 1.58   2   1.12 0.539 1.82, 4.06 -0.36
NZO129SF1 m 3.32 0.0   1   0.0 0.0 3.32, 3.32 -0.15
NZOAF1 f 1.58 0.801   3 0.462 0.506 0.8, 2.4 -1.3
NZOB6F1 m 4.63 0.0   1   0.0 0.0 4.63, 4.63 0.93
NZONODF1 f 6.89 0.0   1   0.0 0.0 6.89, 6.89 2.38
NZONODF1 m 2.12 0.587   2   0.415 0.276 1.71, 2.54 -1.13
NZOWSBF1 f 3.7 0.865   3 0.5 0.234 2.98, 4.66 0.17
PWK129SF1 f 5.16 3.36   4 1.68 0.65 2.1, 8.38 1.18
PWKAF1 f 1.44 0.219   2   0.155 0.153 1.28, 1.59 -1.39
PWKAF1 m 3.61 1.73   2   1.22 0.478 2.39, 4.83 0.09
PWKB6F1 m 3.71 0.955   2   0.675 0.258 3.03, 4.38 0.17
PWKNODF1 f 3.87 0.0   1   0.0 0.0 3.87, 3.87 0.29
PWKNODF1 m 3.06 0.636   2   0.45 0.208 2.61, 3.51 -0.36
WSB129SF1 f 4.32 2.92   3 1.68 0.675 2.22, 7.65 0.6
WSBAF1 f 0.86 0.0   1   0.0 0.0 0.86, 0.86 -1.8
WSBAF1 m 3.03 0.163   2   0.115 0.0538 2.91, 3.14 -0.38
WSBB6F1 f 4.18 0.325   2   0.23 0.0778 3.95, 4.41 0.5
WSBB6F1 m 3.35 1.82   3 1.05 0.543 2.18, 5.44 -0.12
WSBCASTF1 m 2.15 0.862   4 0.431 0.4 1.31, 3.24 -1.11
WSB/EiJ f 2.54 0.0919   2   0.065 0.0361 2.48, 2.61 -0.63
WSBNODF1 f 3.57 0.0   1   0.0 0.0 3.57, 3.57 0.08
WSBNODF1 m 3.63 1.16   2   0.82 0.319 2.81, 4.45 0.11
WSBNZOF1 f 3.76 1.22   6 0.5 0.325 2.09, 5.08 0.21
WSBNZOF1 m 3.4 0.594   2   0.42 0.175 2.98, 3.82 -0.08
WSBPWKF1 f 1.44 0.318   2   0.225 0.222 1.21, 1.66 -1.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f 6.035 1.0017 8.0514 4.0186
129SAF1 m 4.8067 0.8179 6.453 3.1603
129SB6F1 f 3.5933 0.8179 5.2397 1.947
129SB6F1 m 6.415 0.7083 7.8408 4.9892
129SWSBF1 f 3.1625 0.7083 4.5883 1.7367
129SWSBF1 m 2.135 1.0017 4.1514 0.1186
B6NODF1 f 5.145 1.0017 7.1614 3.1286
B6NODF1 m 6.155 1.0017 8.1714 4.1386
B6NZOF1 f 4.74 0.7083 6.1658 3.3142
B6NZOF1 m 3.58 1.0017 5.5964 1.5636
CASTPWKF1 f 2.018 0.6335 3.2933 0.7427
CASTPWKF1 m 1.3517 0.5783 2.5158 0.1875
NODCASTF1 f 2.216 0.6335 3.4913 0.9407
NODCASTF1 m 3.25 1.0017 5.2664 1.2336
NODNZOF1 f 4.33 1.0017 6.3464 2.3136
NODNZOF1 m 4.1967 0.8179 5.843 2.5503
PWKAF1 f 1.435 1.0017 3.4514 0.0
PWKAF1 m 3.61 1.0017 5.6264 1.5936
WSBB6F1 f 4.18 1.0017 6.1964 2.1636
WSBB6F1 m 3.3467 0.8179 4.993 1.7003
WSBNZOF1 f 3.7633 0.5783 4.9275 2.5992
WSBNZOF1 m 3.4 1.0017 5.4164 1.3836


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 5.4208 0.6466 6.7224 4.1193
129SB6F1 both 5.0042 0.541 6.0931 3.9152
129SWSBF1 both 2.6487 0.6134 3.8835 1.414
B6NODF1 both 5.65 0.7083 7.0758 4.2242
B6NZOF1 both 4.16 0.6134 5.3948 2.9252
CASTPWKF1 both 1.6848 0.4289 2.5482 0.8215
NODCASTF1 both 2.733 0.5926 3.9259 1.5401
NODNZOF1 both 4.2633 0.6466 5.5649 2.9618
PWKAF1 both 2.5225 0.7083 3.9483 1.0967
WSBB6F1 both 3.7633 0.6466 5.0649 2.4618
WSBNZOF1 both 3.5817 0.5783 4.7458 2.4175




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA