Phenotype measure:   Chesler2   center1_OFT

ID, description, units MPD:43454   center1_OFT   time spent in center during first minute, 10 min test   [s]
Data set, strains Chesler2   CC diallel w/par   41 strains     sex: both     age: 7-15wks
Procedure open field test
Ontology mappings

  STRAIN COMPARISON PLOT
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Chesler2 - time spent in center during first minute, 10 min test



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 60.0 36.7 24.8 16.2 18.7 34.8 19.7 15.4
A ♀ 20.0 35.2 6.87
B6 ♀ 10.3 23.7 36.1 29.1 17.7
CAST ♀ 10.3 15.6 10.9 9.05 6.73
NOD ♀ 29.4 24.6 25.0 12.5 40.8 21.6
NZO ♀ 21.9 17.1 60.0 36.4
PWK ♀ 35.0 9.58 15.0
WSB ♀ 29.9 4.00 25.6 18.4 21.1 9.54 11.3

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 21.1 32.1 27.7 18.2 29.0 12.3 12.7
A ♀ 38.1 6.01 31.5 19.8 16.0
B6 ♀ 36.2 16.4 37.4 33.2
CAST ♀ 16.6 9.34 16.3 20.2 24.3 6.12 5.94
NOD ♀ 48.2 23.2 24.3 15.2 28.8
NZO ♀ 29.5 46.6 22.3
PWK ♀ 37.3 38.8 19.3
WSB ♀ 7.65 19.9 12.9 12.0 17.5

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested41 strains39 strains
Mean of the strain means22.6   s 22.8   s
Median of the strain means20.0   s 20.2   s
SD of the strain means± 12.9 ± 11.1
Coefficient of variation (CV)0.571 0.488
Min–max range of strain means4.00   –   60.0   s 5.94   –   48.2   s
Mean sample size per strain2.1   mice 2.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 10.0212 10.0212 0.1136 0.7377
strain 10 5664.0521 566.4052 6.4186 < 0.0001
sex:strain 10 1448.0445 144.8044 1.641 0.125
Residuals 46 4059.2127 88.2438


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 60.0 0.0   1   0.0 0.0 60.0, 60.0 2.9
129SAF1 f 36.7 20.2   2   14.2 0.55 22.4, 50.9 1.09
129SAF1 m 21.1 1.5   3 0.866 0.0711 19.7, 22.7 -0.15
129SB6F1 f 24.8 1.86   3 1.08 0.0753 22.6, 26.1 0.17
129SB6F1 m 32.1 7.57   4 3.78 0.236 22.4, 39.3 0.83
129SCASTF1 f 16.2 5.32   2   3.76 0.329 12.4, 19.9 -0.5
129SCASTF1 m 27.7 0.0   1   0.0 0.0 27.7, 27.7 0.44
129SNODF1 f 18.7 0.0   1   0.0 0.0 18.7, 18.7 -0.3
129SNODF1 m 18.2 9.02   2   6.37 0.496 11.8, 24.6 -0.41
129SNZOF1 f 34.8 0.0   1   0.0 0.0 34.8, 34.8 0.94
129SNZOF1 m 29.0 7.88   3 4.55 0.272 22.9, 37.9 0.55
129SPWKF1 f 19.7 7.44   4 3.72 0.378 11.9, 28.7 -0.22
129SPWKF1 m 12.3 0.0   1   0.0 0.0 12.3, 12.3 -0.94
129SWSBF1 f 15.4 6.04   4 3.02 0.392 7.21, 20.5 -0.56
129SWSBF1 m 12.7 0.849   2   0.6 0.0669 12.1, 13.3 -0.91
AB6F1 f 20.0 0.0   1   0.0 0.0 20.0, 20.0 -0.2
AB6F1 m 38.1 6.06   3 3.5 0.159 32.1, 44.2 1.37
ACASTF1 m 6.01 0.0   1   0.0 0.0 6.01, 6.01 -1.51
ANODF1 m 31.5 9.94   5 4.45 0.316 18.1, 44.6 0.78
ANZOF1 f 35.2 15.5   2   11.0 0.442 24.2, 46.2 0.98
APWKF1 f 6.87 0.0   1   0.0 0.0 6.87, 6.87 -1.22
APWKF1 m 19.8 0.0   1   0.0 0.0 19.8, 19.8 -0.27
AWSBF1 m 16.0 0.0   1   0.0 0.0 16.0, 16.0 -0.61
B6129SF1/J f 10.3 14.4   2   10.2 1.4 0.13, 20.4 -0.95
B6AF1/J f 23.7 0.0   1   0.0 0.0 23.7, 23.7 0.09
B6AF1/J m 36.2 6.15   2   4.35 0.17 31.9, 40.6 1.2
B6CASTF1 m 16.4 10.9   2   7.71 0.665 8.68, 24.1 -0.58
B6NODF1 f 36.1 2.39   2   1.69 0.0662 34.4, 37.8 1.05
B6NODF1 m 37.4 7.45   2   5.27 0.199 32.1, 42.7 1.31
B6NZOF1 f 29.1 11.0   4 5.52 0.379 18.8, 42.7 0.5
B6NZOF1 m 33.2 6.53   2   4.62 0.197 28.6, 37.8 0.93
B6PWKF1 f 17.7 7.04   2   4.97 0.397 12.8, 22.7 -0.38
CAST129SF1 m 16.6 5.58   3 3.22 0.336 11.5, 22.6 -0.56
CASTAF1 f 10.3 0.0   1   0.0 0.0 10.3, 10.3 -0.95
CASTAF1 m 9.34 4.33   2   3.06 0.464 6.27, 12.4 -1.21
CASTB6F1 f 15.6 0.0   1   0.0 0.0 15.6, 15.6 -0.54
CASTB6F1 m 16.3 4.73   3 2.73 0.29 10.9, 19.4 -0.59
CASTNODF1 m 20.2 10.1   3 5.81 0.498 8.88, 28.2 -0.24
CASTNZOF1 f 10.9 6.26   3 3.61 0.574 4.0, 16.2 -0.91
CASTNZOF1 m 24.3 0.0   1   0.0 0.0 24.3, 24.3 0.13
CASTPWKF1 f 9.05 3.28   5 1.47 0.363 3.4, 11.5 -1.05
CASTPWKF1 m 6.12 1.84   6 0.75 0.3 3.6, 9.21 -1.5
CASTWSBF1 f 6.73 3.2   2   2.27 0.476 4.47, 9.0 -1.23
CASTWSBF1 m 5.94 0.0   1   0.0 0.0 5.94, 5.94 -1.51
NOD129SF1 f 29.4 0.0   1   0.0 0.0 29.4, 29.4 0.53
NOD129SF1 m 48.2 13.7   2   9.67 0.284 38.5, 57.9 2.28
NODAF1 f 24.6 0.0   1   0.0 0.0 24.6, 24.6 0.15
NODAF1 m 23.2 0.0   1   0.0 0.0 23.2, 23.2 0.03
NODB6F1 f 25.0 0.0   1   0.0 0.0 25.0, 25.0 0.19
NODB6F1 m 24.3 4.08   2   2.88 0.168 21.4, 27.2 0.13
NODCASTF1 f 12.5 3.68   5 1.65 0.295 8.68, 18.6 -0.78
NODCASTF1 m 15.2 0.94   2   0.665 0.0618 14.6, 15.9 -0.68
NODNZOF1 f 40.8 7.61   2   5.38 0.187 35.4, 46.1 1.41
NODNZOF1 m 28.8 21.3   3 12.3 0.739 4.8, 45.4 0.54
NODPWKF1 f 21.6 0.0   1   0.0 0.0 21.6, 21.6 -0.08
NZO129SF1 f 21.9 20.0   2   14.1 0.911 7.81, 36.1 -0.05
NZO129SF1 m 29.5 0.0   1   0.0 0.0 29.5, 29.5 0.6
NZOAF1 f 17.1 8.65   3 4.99 0.505 9.21, 26.4 -0.43
NZOB6F1 m 46.6 0.0   1   0.0 0.0 46.6, 46.6 2.13
NZONODF1 f 60.0 0.0   1   0.0 0.0 60.0, 60.0 2.9
NZONODF1 m 22.3 16.5   2   11.7 0.741 10.6, 34.0 -0.05
NZOWSBF1 f 36.4 13.4   3 7.74 0.369 27.7, 51.8 1.07
PWK129SF1 f 35.0 17.9   4 8.96 0.511 13.3, 52.3 0.96
PWKAF1 f 9.58 1.56   2   1.1 0.162 8.48, 10.7 -1.01
PWKAF1 m 37.3 24.9   2   17.6 0.667 19.7, 54.9 1.3
PWKB6F1 m 38.8 6.37   2   4.51 0.164 34.3, 43.3 1.43
PWKNODF1 f 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.59
PWKNODF1 m 19.3 4.53   2   3.2 0.235 16.1, 22.5 -0.32
WSB129SF1 f 29.9 16.3   3 9.43 0.546 18.2, 48.6 0.57
WSBAF1 f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -1.44
WSBAF1 m 7.65 5.43   2   3.84 0.71 3.81, 11.5 -1.36
WSBB6F1 f 25.6 10.6   2   7.47 0.413 18.1, 33.1 0.23
WSBB6F1 m 19.9 11.6   3 6.68 0.582 6.54, 27.2 -0.26
WSBCASTF1 m 12.9 4.59   4 2.29 0.354 6.14, 16.0 -0.89
WSB/EiJ f 11.3 7.27   2   5.14 0.644 6.14, 16.4 -0.87
WSBNODF1 f 18.4 0.0   1   0.0 0.0 18.4, 18.4 -0.33
WSBNODF1 m 12.0 2.31   2   1.63 0.193 10.3, 13.6 -0.97
WSBNZOF1 f 21.1 12.7   6 5.2 0.602 0.67, 38.6 -0.12
WSBNZOF1 m 17.5 1.27   2   0.9 0.0726 16.6, 18.4 -0.48
WSBPWKF1 f 9.54 3.87   2   2.73 0.405 6.81, 12.3 -1.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f 36.67 6.6424 50.0405 23.2995
129SAF1 m 21.0833 5.4235 32.0003 10.1664
129SB6F1 f 24.7533 5.4235 35.6703 13.8364
129SB6F1 m 32.0975 4.6969 41.5519 22.6431
129SWSBF1 f 15.4 4.6969 24.8544 5.9456
129SWSBF1 m 12.68 6.6424 26.0505 0.0
B6NODF1 f 36.09 6.6424 49.4605 22.7195
B6NODF1 m 37.4 6.6424 50.7705 24.0295
B6NZOF1 f 29.1325 4.6969 38.5869 19.6781
B6NZOF1 m 33.22 6.6424 46.5905 19.8495
CASTPWKF1 f 9.046 4.201 17.5023 0.5897
CASTPWKF1 m 6.1183 3.835 13.8378 0.0
NODCASTF1 f 12.468 4.201 20.9243 4.0117
NODCASTF1 m 15.215 6.6424 28.5855 1.8445
NODNZOF1 f 40.75 6.6424 54.1205 27.3795
NODNZOF1 m 28.76 5.4235 39.677 17.843
PWKAF1 f 9.58 6.6424 22.9505 0.0
PWKAF1 m 37.275 6.6424 50.6455 23.9045
WSBB6F1 f 25.6 6.6424 38.9705 12.2295
WSBB6F1 m 19.8867 5.4235 30.8036 8.9697
WSBNZOF1 f 21.14 3.835 28.8595 13.4205
WSBNZOF1 m 17.52 6.6424 30.8905 4.1495


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 28.8767 4.2877 37.5073 20.246
129SB6F1 both 28.4254 3.5873 35.6463 21.2045
129SWSBF1 both 14.04 4.0676 22.2277 5.8523
B6NODF1 both 36.745 4.6969 46.1994 27.2906
B6NZOF1 both 31.1763 4.0676 39.364 22.9885
CASTPWKF1 both 7.5822 2.8441 13.3071 1.8573
NODCASTF1 both 13.8415 3.9297 21.7516 5.9314
NODNZOF1 both 34.755 4.2877 43.3856 26.1244
PWKAF1 both 23.4275 4.6969 32.8819 13.9731
WSBB6F1 both 22.7433 4.2877 31.374 14.1127
WSBNZOF1 both 19.33 3.835 27.0495 11.6105




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CKB, or AXBBXA