Phenotype measure:   Chesler2   distance3_OFT


  STRAIN COMPARISON PLOT
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Chesler2 - distance traveled during first 3 min, 10 min test



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 182 1081 1368 1343 1563 719 1504 1706
A ♀ 1394 835 1533
B6 ♀ 1073 1402 2035 1133 1583
CAST ♀ 1256 1498 1159 959 1315
NOD ♀ 1309 1144 2369 1931 841 2213
NZO ♀ 1023 810 450 1053
PWK ♀ 1255 934 1922
WSB ♀ 1374 1705 1757 1874 902 1693 1972

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 942 1605 1229 1228 553 2438 1225
A ♀ 1046 1172 1297 1320 1837
B6 ♀ 1197 2067 2129 986
CAST ♀ 1389 1160 1667 1166 1111 891 2046
NOD ♀ 902 1088 1891 1805 997
NZO ♀ 729 1018 834
PWK ♀ 886 1636 1684
WSB ♀ 1368 1706 1521 1535 614

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested41 strains39 strains
Mean of the strain means1346   cm 1331   cm
Median of the strain means1343   cm 1228   cm
SD of the strain means± 466 ± 443
Coefficient of variation (CV)0.347 0.333
Min–max range of strain means182   –   2369   cm 553   –   2438   cm
Mean sample size per strain2.1   mice 2.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 131793.1168 131793.1168 1.3933 0.2439
strain 10 11754248.2034 1175424.8203 12.4266 < 0.0001
sex:strain 10 563150.3445 56315.0344 0.5954 0.8093
Residuals 46 4351125.1815 94589.6779


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 182.0 0.0   1   0.0 0.0 182.0, 182.0 -2.49
129SAF1 f 1081.0 764.0   2   540.0 0.707 540.0, 1621.0 -0.57
129SAF1 m 942.0 379.0   3 219.0 0.403 515.0, 1239.0 -0.88
129SB6F1 f 1368.0 369.0   3 213.0 0.27 1055.0, 1775.0 0.05
129SB6F1 m 1605.0 363.0   4 181.0 0.226 1091.0, 1945.0 0.62
129SCASTF1 f 1343.0 951.0   2   672.0 0.708 670.0, 2015.0 -0.01
129SCASTF1 m 1229.0 0.0   1   0.0 0.0 1229.0, 1229.0 -0.23
129SNODF1 f 1563.0 0.0   1   0.0 0.0 1563.0, 1563.0 0.47
129SNODF1 m 1228.0 69.1   2   48.9 0.0563 1179.0, 1277.0 -0.23
129SNZOF1 f 719.0 0.0   1   0.0 0.0 719.0, 719.0 -1.34
129SNZOF1 m 553.0 282.0   3 163.0 0.51 241.0, 792.0 -1.76
129SPWKF1 f 1504.0 434.0   4 217.0 0.288 938.0, 1947.0 0.34
129SPWKF1 m 2438.0 0.0   1   0.0 0.0 2438.0, 2438.0 2.5
129SWSBF1 f 1706.0 284.0   4 142.0 0.167 1305.0, 1977.0 0.77
129SWSBF1 m 1225.0 227.0   2   160.0 0.185 1065.0, 1386.0 -0.24
AB6F1 f 1394.0 0.0   1   0.0 0.0 1394.0, 1394.0 0.1
AB6F1 m 1046.0 300.0   3 173.0 0.286 719.0, 1307.0 -0.64
ACASTF1 m 1172.0 0.0   1   0.0 0.0 1172.0, 1172.0 -0.36
ANODF1 m 1297.0 338.0   5 151.0 0.261 753.0, 1677.0 -0.08
ANZOF1 f 835.0 190.0   2   134.0 0.228 700.0, 969.0 -1.09
APWKF1 f 1533.0 0.0   1   0.0 0.0 1533.0, 1533.0 0.4
APWKF1 m 1320.0 0.0   1   0.0 0.0 1320.0, 1320.0 -0.03
AWSBF1 m 1837.0 0.0   1   0.0 0.0 1837.0, 1837.0 1.14
B6129SF1/J f 1073.0 146.0   2   103.0 0.136 970.0, 1176.0 -0.58
B6AF1/J f 1402.0 0.0   1   0.0 0.0 1402.0, 1402.0 0.12
B6AF1/J m 1197.0 240.0   2   170.0 0.201 1027.0, 1367.0 -0.3
B6CASTF1 m 2067.0 34.1   2   24.1 0.0165 2043.0, 2091.0 1.66
B6NODF1 f 2035.0 657.0   2   465.0 0.323 1570.0, 2500.0 1.48
B6NODF1 m 2129.0 879.0   2   622.0 0.413 1508.0, 2751.0 1.8
B6NZOF1 f 1133.0 111.0   4 55.7 0.0984 1067.0, 1299.0 -0.46
B6NZOF1 m 986.0 118.0   2   83.5 0.12 903.0, 1070.0 -0.78
B6PWKF1 f 1583.0 47.4   2   33.5 0.03 1550.0, 1617.0 0.51
CAST129SF1 m 1389.0 302.0   3 174.0 0.217 1048.0, 1625.0 0.13
CASTAF1 f 1256.0 0.0   1   0.0 0.0 1256.0, 1256.0 -0.19
CASTAF1 m 1160.0 367.0   2   259.0 0.316 901.0, 1419.0 -0.39
CASTB6F1 f 1498.0 0.0   1   0.0 0.0 1498.0, 1498.0 0.33
CASTB6F1 m 1667.0 253.0   3 146.0 0.152 1392.0, 1892.0 0.76
CASTNODF1 m 1166.0 139.0   3 80.4 0.119 1041.0, 1317.0 -0.37
CASTNZOF1 f 1159.0 412.0   3 238.0 0.356 780.0, 1597.0 -0.4
CASTNZOF1 m 1111.0 0.0   1   0.0 0.0 1111.0, 1111.0 -0.5
CASTPWKF1 f 959.0 175.0   5 78.4 0.183 773.0, 1213.0 -0.83
CASTPWKF1 m 891.0 147.0   6 60.2 0.166 689.0, 1097.0 -0.99
CASTWSBF1 f 1315.0 150.0   2   106.0 0.114 1209.0, 1421.0 -0.07
CASTWSBF1 m 2046.0 0.0   1   0.0 0.0 2046.0, 2046.0 1.62
NOD129SF1 f 1309.0 0.0   1   0.0 0.0 1309.0, 1309.0 -0.08
NOD129SF1 m 902.0 122.0   2   86.1 0.135 816.0, 988.0 -0.97
NODAF1 f 1144.0 0.0   1   0.0 0.0 1144.0, 1144.0 -0.43
NODAF1 m 1088.0 0.0   1   0.0 0.0 1088.0, 1088.0 -0.55
NODB6F1 f 2369.0 0.0   1   0.0 0.0 2369.0, 2369.0 2.19
NODB6F1 m 1891.0 136.0   2   96.2 0.0719 1795.0, 1988.0 1.26
NODCASTF1 f 1931.0 190.0   5 84.9 0.0983 1726.0, 2121.0 1.25
NODCASTF1 m 1805.0 16.4   2   11.6 0.0091 1793.0, 1816.0 1.07
NODNZOF1 f 841.0 81.7   2   57.8 0.0972 783.0, 899.0 -1.08
NODNZOF1 m 997.0 169.0   3 97.7 0.17 822.0, 1160.0 -0.75
NODPWKF1 f 2213.0 0.0   1   0.0 0.0 2213.0, 2213.0 1.86
NZO129SF1 f 1023.0 19.9   2   14.1 0.0195 1009.0, 1037.0 -0.69
NZO129SF1 m 729.0 0.0   1   0.0 0.0 729.0, 729.0 -1.36
NZOAF1 f 810.0 316.0   3 182.0 0.39 575.0, 1169.0 -1.15
NZOB6F1 m 1018.0 0.0   1   0.0 0.0 1018.0, 1018.0 -0.71
NZONODF1 f 450.0 0.0   1   0.0 0.0 450.0, 450.0 -1.92
NZONODF1 m 834.0 49.5   2   35.0 0.0594 799.0, 869.0 -1.12
NZOWSBF1 f 1053.0 401.0   3 232.0 0.381 787.0, 1514.0 -0.63
PWK129SF1 f 1255.0 745.0   4 373.0 0.594 756.0, 2359.0 -0.19
PWKAF1 f 934.0 151.0   2   107.0 0.162 828.0, 1041.0 -0.88
PWKAF1 m 886.0 163.0   2   115.0 0.184 771.0, 1001.0 -1.01
PWKB6F1 m 1636.0 445.0   2   314.0 0.272 1322.0, 1951.0 0.69
PWKNODF1 f 1922.0 0.0   1   0.0 0.0 1922.0, 1922.0 1.24
PWKNODF1 m 1684.0 26.4   2   18.7 0.0157 1665.0, 1702.0 0.8
WSB129SF1 f 1374.0 426.0   3 246.0 0.31 883.0, 1624.0 0.06
WSBAF1 f 1705.0 0.0   1   0.0 0.0 1705.0, 1705.0 0.77
WSBAF1 m 1368.0 46.7   2   33.0 0.0342 1335.0, 1401.0 0.08
WSBB6F1 f 1757.0 191.0   2   135.0 0.109 1622.0, 1892.0 0.88
WSBB6F1 m 1706.0 163.0   3 93.9 0.0954 1543.0, 1868.0 0.85
WSBCASTF1 m 1521.0 297.0   4 148.0 0.195 1304.0, 1960.0 0.43
WSB/EiJ f 1972.0 583.0   2   412.0 0.296 1560.0, 2384.0 1.34
WSBNODF1 f 1874.0 0.0   1   0.0 0.0 1874.0, 1874.0 1.13
WSBNODF1 m 1535.0 807.0   2   570.0 0.525 965.0, 2106.0 0.46
WSBNZOF1 f 902.0 369.0   6 151.0 0.41 586.0, 1416.0 -0.95
WSBNZOF1 m 614.0 3.88   2   2.74 0.00632 611.0, 617.0 -1.62
WSBPWKF1 f 1693.0 331.0   2   234.0 0.196 1458.0, 1927.0 0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 f 1080.655 217.4738 1518.407 642.903
129SAF1 m 942.1633 177.5666 1299.5863 584.7403
129SB6F1 f 1368.2533 177.5666 1725.6763 1010.8303
129SB6F1 m 1604.935 153.7772 1914.4724 1295.3976
129SWSBF1 f 1705.6875 153.7772 2015.2249 1396.1501
129SWSBF1 m 1225.455 217.4738 1663.207 787.703
B6NODF1 f 2034.755 217.4738 2472.507 1597.003
B6NODF1 m 2129.475 217.4738 2567.227 1691.723
B6NZOF1 f 1132.755 153.7772 1442.2924 823.2176
B6NZOF1 m 986.345 217.4738 1424.097 548.593
CASTPWKF1 f 958.782 137.5425 1235.6407 681.9233
CASTPWKF1 m 890.855 125.5585 1143.5912 638.1188
NODCASTF1 f 1930.818 137.5425 2207.6767 1653.9593
NODCASTF1 m 1804.57 217.4738 2242.322 1366.818
NODNZOF1 f 840.89 217.4738 1278.642 403.138
NODNZOF1 m 996.83 177.5666 1354.253 639.407
PWKAF1 f 934.385 217.4738 1372.137 496.633
PWKAF1 m 885.68 217.4738 1323.432 447.928
WSBB6F1 f 1757.015 217.4738 2194.767 1319.263
WSBB6F1 m 1706.04 177.5666 2063.463 1348.617
WSBNZOF1 f 902.1533 125.5585 1154.8896 649.4171
WSBNZOF1 m 614.075 217.4738 1051.827 176.323


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SAF1 both 1011.4092 140.3787 1293.9769 728.8415
129SB6F1 both 1486.5942 117.4493 1723.0073 1250.1811
129SWSBF1 both 1465.5713 133.1749 1733.6385 1197.504
B6NODF1 both 2082.115 153.7772 2391.6524 1772.5776
B6NZOF1 both 1059.55 133.1749 1327.6173 791.4827
CASTPWKF1 both 924.8185 93.1167 1112.2527 737.3843
NODCASTF1 both 1867.694 128.6592 2126.6716 1608.7164
NODNZOF1 both 918.86 140.3787 1201.4277 636.2923
PWKAF1 both 910.0325 153.7772 1219.5699 600.4951
WSBB6F1 both 1731.5275 140.3787 2014.0952 1448.9598
WSBNZOF1 both 758.1142 125.5585 1010.8504 505.3779




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CKB, or AXBBXA