Phenotype measure:   Chesler2   MPV

ID, description, units MPD:43429   MPV   mean platelet volume (MPV)   [fL]
Data set, strains Chesler2   CC diallel w/par   38 strains     sex: both     age: 7-15wks
Procedure complete blood count
Ontology mappings

  STRAIN COMPARISON PLOT
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Chesler2 - mean platelet volume (MPV)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 5.53 5.60 5.77 6.14 5.12
A ♀ 6.04 6.06 5.93
B6 ♀ 6.25 6.49 5.79 5.88 6.20 5.34
CAST ♀ 7.30 5.30 6.87 5.70 5.48 5.90
NOD ♀ 5.26 5.94 5.90 6.02
NZO ♀ 6.42 5.74 4.96
PWK ♀ 5.60 5.94 5.43 6.71
WSB ♀ 4.91 5.43 5.26 5.14 5.32 4.90 4.46

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 5.61 5.76 5.35 5.97 5.81
A ♀ 5.72 6.01 5.65 5.71 5.83
B6 ♀ 5.53 5.32 6.06 5.76
CAST ♀ 6.04 6.58 5.63 8.32 5.34 6.26 5.67
NOD ♀ 5.47 5.60
NZO ♀ 5.86 6.28 6.71
PWK ♀ 5.02 8.39
WSB ♀ 5.64 5.30 6.15 5.24 5.56 5.53

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested38 strains34 strains
Mean of the strain means5.74   fL 5.90   fL
Median of the strain means5.75   fL 5.71   fL
SD of the strain means± 0.581 ± 0.722
Coefficient of variation (CV)0.101 0.122
Min–max range of strain means4.46   –   7.30   fL 5.02   –   8.39   fL
Mean sample size per strain1.9   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.8081 0.8081 1.9768 0.1628
strain 10 48.7809 4.8781 11.9325 < 0.0001
sex:strain 10 10.4686 1.0469 2.5608 0.0085
Residuals 100 40.8806 0.4088


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.53 0.106   2   0.075 0.0192 5.45, 5.6 -0.36
129S1/SvImJ m 5.61 0.53   2   0.375 0.0946 5.23, 5.98 -0.4
129SAF1 f 5.6 0.0   1   0.0 0.0 5.6, 5.6 -0.24
129SAF1 m 5.76 0.29   2   0.205 0.0503 5.56, 5.97 -0.2
129SB6F1 f 5.77 0.424   2   0.3 0.0735 5.47, 6.07 0.06
129SB6F1 m 5.35 0.339   2   0.24 0.0634 5.11, 5.59 -0.76
129SCASTF1 f 6.14 0.636   2   0.45 0.104 5.69, 6.59 0.69
129SNODF1 m 5.97 0.0141   2   0.01 0.00237 5.96, 5.98 0.09
129SNZOF1 m 5.81 0.0849   2   0.06 0.0146 5.75, 5.87 -0.13
129SPWKF1 f 5.12 0.0   1   0.0 0.0 5.12, 5.12 -1.06
AB6F1 f 6.06 0.0   1   0.0 0.0 6.06, 6.06 0.55
AB6F1 m 6.01 0.299   4 0.149 0.0497 5.7, 6.36 0.15
A/J f 6.04 0.622   2   0.44 0.103 5.6, 6.48 0.52
A/J m 5.72 0.518   6 0.211 0.0905 5.24, 6.49 -0.25
ANODF1 m 5.65 0.37   7 0.14 0.0654 5.11, 6.13 -0.35
ANZOF1 f 5.93 0.0   1   0.0 0.0 5.93, 5.93 0.33
APWKF1 m 5.71 0.0   1   0.0 0.0 5.71, 5.71 -0.27
AWSBF1 m 5.83 0.0   1   0.0 0.0 5.83, 5.83 -0.1
B6129SF1/J f 6.25 0.191   2   0.135 0.0305 6.12, 6.39 0.88
B6AF1/J f 6.49 0.0   1   0.0 0.0 6.49, 6.49 1.29
B6AF1/J m 5.53 0.0   1   0.0 0.0 5.53, 5.53 -0.52
B6NODF1 f 5.88 0.0   1   0.0 0.0 5.88, 5.88 0.25
B6NODF1 m 6.06 0.262   2   0.185 0.0431 5.88, 6.25 0.22
B6NZOF1 f 6.2 0.0   1   0.0 0.0 6.2, 6.2 0.8
B6NZOF1 m 5.76 0.0   1   0.0 0.0 5.76, 5.76 -0.2
B6PWKF1 f 5.34 0.0   1   0.0 0.0 5.34, 5.34 -0.68
C57BL/6J f 5.79 0.373   20 0.0835 0.0645 5.17, 6.53 0.09
C57BL/6J m 5.32 0.249   37 0.0409 0.0468 4.93, 5.96 -0.81
CAST129SF1 m 6.04 0.0566   2   0.04 0.00937 6.0, 6.08 0.19
CASTAF1 f 7.3 0.0   1   0.0 0.0 7.3, 7.3 2.69
CASTAF1 m 6.58 0.601   2   0.425 0.0913 6.16, 7.01 0.94
CASTB6F1 f 5.3 0.0   1   0.0 0.0 5.3, 5.3 -0.75
CASTB6F1 m 5.63 0.566   3 0.327 0.101 4.98, 5.98 -0.38
CAST/EiJ f 6.87 0.354   5 0.158 0.0515 6.47, 7.27 1.95
CAST/EiJ m 8.32 0.792   2   0.56 0.0952 7.76, 8.88 3.35
CASTNODF1 m 5.34 0.0   1   0.0 0.0 5.34, 5.34 -0.78
CASTNZOF1 f 5.7 0.579   4 0.29 0.102 5.19, 6.29 -0.06
CASTNZOF1 m 6.26 0.0   1   0.0 0.0 6.26, 6.26 0.5
CASTPWKF1 f 5.48 0.417   5 0.186 0.0761 5.03, 6.07 -0.44
CASTPWKF1 m 5.67 0.291   6 0.119 0.0514 5.18, 5.87 -0.32
CASTWSBF1 f 5.9 0.24   2   0.17 0.0407 5.73, 6.07 0.28
NODAF1 f 5.26 0.0   1   0.0 0.0 5.26, 5.26 -0.82
NODB6F1 f 5.94 0.216   3 0.125 0.0364 5.7, 6.12 0.35
NODNZOF1 f 6.02 0.523   2   0.37 0.0869 5.65, 6.39 0.49
NODNZOF1 m 5.6 0.58   2   0.41 0.104 5.19, 6.01 -0.42
NOD/ShiLtJ f 5.9 0.241   3 0.139 0.0409 5.7, 6.17 0.28
NOD/ShiLtJ m 5.47 0.287   3 0.166 0.0526 5.14, 5.68 -0.6
NZO129SF1 f 6.42 0.0   1   0.0 0.0 6.42, 6.42 1.17
NZOAF1 f 5.74 0.0   1   0.0 0.0 5.74, 5.74 0.0
NZOB6F1 m 5.86 0.0   1   0.0 0.0 5.86, 5.86 -0.06
NZO/HlLtJ m 6.71 0.0   1   0.0 0.0 6.71, 6.71 1.12
NZONODF1 m 6.28 0.0   1   0.0 0.0 6.28, 6.28 0.52
NZOWSBF1 f 4.96 0.127   3 0.0731 0.0255 4.82, 5.06 -1.34
PWK129SF1 f 5.6 0.0   1   0.0 0.0 5.6, 5.6 -0.24
PWKAF1 f 5.94 0.0   1   0.0 0.0 5.94, 5.94 0.35
PWKAF1 m 5.02 0.0   1   0.0 0.0 5.02, 5.02 -1.22
PWKNODF1 f 5.43 0.0   1   0.0 0.0 5.43, 5.43 -0.53
PWK/PhJ f 6.71 0.587   2   0.415 0.0874 6.3, 7.13 1.67
PWK/PhJ m 8.39 2.94   4 1.47 0.35 6.62, 12.8 3.44
WSB129SF1 f 4.91 0.0   1   0.0 0.0 4.91, 4.91 -1.42
WSBAF1 f 5.43 0.0   1   0.0 0.0 5.43, 5.43 -0.53
WSBAF1 m 5.64 0.509   2   0.36 0.0903 5.28, 6.0 -0.36
WSBB6F1 f 5.26 0.339   2   0.24 0.0645 5.02, 5.5 -0.82
WSBB6F1 m 5.3 0.337   3 0.195 0.0636 4.92, 5.57 -0.83
WSBCASTF1 m 6.15 0.136   3 0.0784 0.0221 5.99, 6.23 0.34
WSB/EiJ f 4.46 0.00707   2   0.005 0.00159 4.45, 4.46 -2.2
WSB/EiJ m 5.53 0.0   1   0.0 0.0 5.53, 5.53 -0.52
WSBNODF1 f 5.14 0.0   1   0.0 0.0 5.14, 5.14 -1.03
WSBNODF1 m 5.24 0.467   2   0.33 0.0891 4.91, 5.57 -0.92
WSBNZOF1 f 5.32 0.73   6 0.298 0.137 4.73, 6.63 -0.72
WSBNZOF1 m 5.56 0.656   4 0.328 0.118 4.91, 6.45 -0.47
WSBPWKF1 f 4.9 0.0566   2   0.04 0.0115 4.86, 4.94 -1.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.525 0.4521 6.422 4.628
129S1/SvImJ m 5.605 0.4521 6.502 4.708
129SB6F1 f 5.77 0.4521 6.667 4.873
129SB6F1 m 5.35 0.4521 6.247 4.453
A/J f 6.04 0.4521 6.937 5.143
A/J m 5.7217 0.261 6.2395 5.2038
C57BL/6J f 5.7915 0.143 6.0751 5.5079
C57BL/6J m 5.3181 0.1051 5.5266 5.1096
CAST/EiJ f 6.868 0.2859 7.4353 6.3007
CAST/EiJ m 8.32 0.4521 9.217 7.423
CASTPWKF1 f 5.48 0.2859 6.0473 4.9127
CASTPWKF1 m 5.67 0.261 6.1879 5.1521
NODNZOF1 f 6.02 0.4521 6.917 5.123
NODNZOF1 m 5.6 0.4521 6.497 4.703
NOD/ShiLtJ f 5.9033 0.3691 6.6357 5.171
NOD/ShiLtJ m 5.4667 0.3691 6.199 4.7343
PWK/PhJ f 6.715 0.4521 7.612 5.818
PWK/PhJ m 8.3925 0.3197 9.0268 7.7582
WSBB6F1 f 5.26 0.4521 6.157 4.363
WSBB6F1 m 5.2967 0.3691 6.029 4.5643
WSBNZOF1 f 5.3233 0.261 5.8412 4.8055
WSBNZOF1 m 5.5625 0.3197 6.1968 4.9282


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.565 0.3197 6.1993 4.9307
129SB6F1 both 5.56 0.3197 6.1943 4.9257
A/J both 5.8808 0.261 6.3987 5.363
C57BL/6J both 5.5548 0.0887 5.7308 5.3788
CAST/EiJ both 7.594 0.2675 8.1247 7.0633
CASTPWKF1 both 5.575 0.1936 5.9591 5.1909
NODNZOF1 both 5.81 0.3197 6.4443 5.1757
NOD/ShiLtJ both 5.685 0.261 6.2029 5.1671
PWK/PhJ both 7.5537 0.2769 8.103 7.0045
WSBB6F1 both 5.2783 0.2918 5.8573 4.6993
WSBNZOF1 both 5.4429 0.2064 5.8523 5.0335




  GENOME-WIDE ASSOCIATION (GWAS) STATIC PLOT
Plot generated with EMMA / pyLMM using 132K SNP array. Click on plot to view at larger size.