Project measure / variable:   Chesler2   MCHC

ID, description, units MPD:43425   MCHC   mean RBC corpuscular hemoglobin concentration (MCHC)   [g/dL]  
Data set, strains Chesler2   CC diallel w/par   49 strains     sex: both     age: 7-15wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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Chesler2 - mean RBC corpuscular hemoglobin concentration (MCHC)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 37.6 31.1 31.6 30.6 — — 30.7 —
A ♀ — 38.2 32.5 — — 32.5 — —
B6 ♀ 33.4 35.3 31.1 — 32.5 32.1 31.6 —
CAST ♀ — 30.1 31.3 29.8 — 32.7 30.2 31.9
NOD ♀ — 31.9 32.3 — 45.5 32.7 — —
NZO ♀ 31.6 32.0 — — — — — 31.6
PWK ♀ 30.8 30.3 — — 31.9 — 37.1 —
WSB ♀ 31.0 31.3 31.3 — 31.6 33.1 32.9 29.4

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 37.5 30.4 31.8 — 31.6 31.3 — —
A ♀ — 33.2 32.8 — 32.1 — 29.6 30.7
B6 ♀ — 32.3 31.0 — 32.3 32.9 — —
CAST ♀ 31.1 30.1 31.5 28.5 31.2 31.8 29.8 —
NOD ♀ — — — — 39.4 32.9 — —
NZO ♀ — — 32.6 — 34.0 33.0 — —
PWK ♀ — 29.8 — — — — 33.6 —
WSB ♀ — 31.9 31.2 30.5 30.9 31.5 — 29.4

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested38 strains34 strains
Mean of the strain means32.5   g/dL 31.9   g/dL
Median of the strain means31.8   g/dL 31.6   g/dL
SD of the strain means± 2.92 ± 2.11
Coefficient of variation (CV)0.0900 0.0661
Min–max range of strain means29.4   –   45.5   g/dL 28.5   –   39.4   g/dL
Mean sample size per strain1.9   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 31.0685 31.0685 9.0604 0.0033
strain 10 1013.5138 101.3514 29.5566 < 0.0001
sex:strain 10 87.9741 8.7974 2.5655 0.0084
Residuals 100 342.9057 3.4291


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 37.6 0.141   2   0.1 0.00376 37.5, 37.7 1.74
129S1/SvImJ m 37.5 0.707   2   0.5 0.0189 37.0, 38.0 2.66
129SAF1 f 31.1 0.0   1   0.0 0.0 31.1, 31.1 -0.48
129SAF1 m 30.4 0.707   2   0.5 0.0232 29.9, 30.9 -0.71
129SB6F1 f 31.6 1.2   2   0.845 0.0378 30.7, 32.4 -0.31
129SB6F1 m 31.8 0.113   2   0.08 0.00356 31.7, 31.8 -0.04
129SCASTF1 f 30.6 0.198   2   0.14 0.00648 30.4, 30.7 -0.65
129SNODF1 m 31.6 0.247   2   0.175 0.00783 31.4, 31.8 -0.14
129SNZOF1 m 31.3 0.269   2   0.19 0.00858 31.1, 31.5 -0.28
129SPWKF1 f 30.7 0.0   1   0.0 0.0 30.7, 30.7 -0.62
AB6F1 f 32.5 0.0   1   0.0 0.0 32.5, 32.5 0.0
AB6F1 m 32.8 1.8   4 0.902 0.055 31.3, 35.4 0.43
A/J f 38.2 0.318   2   0.225 0.00832 38.0, 38.5 1.95
A/J m 33.2 4.76   6 1.94 0.143 29.6, 40.0 0.62
ANODF1 m 32.1 0.744   7 0.281 0.0232 31.2, 33.0 0.1
ANZOF1 f 32.5 0.0   1   0.0 0.0 32.5, 32.5 0.0
APWKF1 m 29.6 0.0   1   0.0 0.0 29.6, 29.6 -1.09
AWSBF1 m 30.7 0.0   1   0.0 0.0 30.7, 30.7 -0.56
B6129SF1/J f 33.4 3.49   2   2.47 0.104 31.0, 35.9 0.31
B6AF1/J f 35.3 0.0   1   0.0 0.0 35.3, 35.3 0.96
B6AF1/J m 32.3 0.0   1   0.0 0.0 32.3, 32.3 0.2
B6NODF1 f 32.5 0.0   1   0.0 0.0 32.5, 32.5 0.0
B6NODF1 m 32.3 0.0778   2   0.055 0.00241 32.2, 32.3 0.2
B6NZOF1 f 32.1 0.0   1   0.0 0.0 32.1, 32.1 -0.14
B6NZOF1 m 32.9 0.0   1   0.0 0.0 32.9, 32.9 0.48
B6PWKF1 f 31.6 0.0   1   0.0 0.0 31.6, 31.6 -0.31
C57BL/6J f 31.1 0.62   20 0.139 0.0199 30.1, 32.1 -0.48
C57BL/6J m 31.0 0.591   37 0.0971 0.019 29.7, 32.3 -0.42
CAST129SF1 m 31.1 1.4   2   0.99 0.045 30.1, 32.1 -0.37
CASTAF1 f 30.1 0.0   1   0.0 0.0 30.1, 30.1 -0.82
CASTAF1 m 30.1 0.764   2   0.54 0.0254 29.6, 30.6 -0.85
CASTB6F1 f 31.3 0.0   1   0.0 0.0 31.3, 31.3 -0.41
CASTB6F1 m 31.5 0.267   3 0.154 0.0085 31.1, 31.6 -0.18
CAST/EiJ f 29.8 0.302   5 0.135 0.0101 29.5, 30.2 -0.92
CAST/EiJ m 28.5 0.955   2   0.675 0.0335 27.8, 29.1 -1.61
CASTNODF1 m 31.2 0.0   1   0.0 0.0 31.2, 31.2 -0.33
CASTNZOF1 f 32.7 2.13   4 1.06 0.0651 31.2, 35.8 0.07
CASTNZOF1 m 31.8 0.0   1   0.0 0.0 31.8, 31.8 -0.04
CASTPWKF1 f 30.2 0.887   5 0.397 0.0294 28.8, 31.1 -0.79
CASTPWKF1 m 29.8 0.438   6 0.179 0.0147 28.9, 30.1 -0.99
CASTWSBF1 f 31.9 3.2   2   2.26 0.101 29.6, 34.1 -0.21
NODAF1 f 31.9 0.0   1   0.0 0.0 31.9, 31.9 -0.21
NODB6F1 f 32.3 0.57   3 0.329 0.0177 31.6, 32.6 -0.07
NODNZOF1 f 32.7 0.431   2   0.305 0.0132 32.4, 33.0 0.07
NODNZOF1 m 32.9 0.976   2   0.69 0.0297 32.2, 33.6 0.48
NOD/ShiLtJ f 45.5 6.62   3 3.82 0.146 40.9, 53.1 4.44
NOD/ShiLtJ m 39.4 0.533   3 0.307 0.0135 38.9, 39.9 3.57
NZO129SF1 f 31.6 0.0   1   0.0 0.0 31.6, 31.6 -0.31
NZOAF1 f 32.0 0.0   1   0.0 0.0 32.0, 32.0 -0.17
NZOB6F1 m 32.6 0.0   1   0.0 0.0 32.6, 32.6 0.34
NZO/HlLtJ m 33.0 0.0   1   0.0 0.0 33.0, 33.0 0.53
NZONODF1 m 34.0 0.0   1   0.0 0.0 34.0, 34.0 1.0
NZOWSBF1 f 31.6 0.457   3 0.264 0.0144 31.1, 31.9 -0.31
PWK129SF1 f 30.8 0.0   1   0.0 0.0 30.8, 30.8 -0.58
PWKAF1 f 30.3 0.0   1   0.0 0.0 30.3, 30.3 -0.75
PWKAF1 m 29.8 0.0   1   0.0 0.0 29.8, 29.8 -0.99
PWKNODF1 f 31.9 0.0   1   0.0 0.0 31.9, 31.9 -0.21
PWK/PhJ f 37.1 1.65   2   1.16 0.0444 35.9, 38.3 1.57
PWK/PhJ m 33.6 5.42   4 2.71 0.161 26.1, 38.0 0.81
WSB129SF1 f 31.0 0.0   1   0.0 0.0 31.0, 31.0 -0.51
WSBAF1 f 31.3 0.0   1   0.0 0.0 31.3, 31.3 -0.41
WSBAF1 m 31.9 1.53   2   1.08 0.0478 30.9, 33.0 0.01
WSBB6F1 f 31.3 0.714   2   0.505 0.0228 30.8, 31.8 -0.41
WSBB6F1 m 31.2 0.774   3 0.447 0.0248 30.5, 32.1 -0.33
WSBCASTF1 m 30.5 0.915   3 0.528 0.03 29.5, 31.1 -0.66
WSB/EiJ f 29.4 2.02   2   1.43 0.0689 27.9, 30.8 -1.06
WSB/EiJ m 29.4 0.0   1   0.0 0.0 29.4, 29.4 -1.18
WSBNODF1 f 31.6 0.0   1   0.0 0.0 31.6, 31.6 -0.31
WSBNODF1 m 30.9 0.297   2   0.21 0.00962 30.6, 31.1 -0.47
WSBNZOF1 f 33.1 1.78   6 0.725 0.0536 31.6, 36.5 0.2
WSBNZOF1 m 31.5 1.27   4 0.636 0.0404 29.8, 32.9 -0.18
WSBPWKF1 f 32.9 2.82   2   1.99 0.0857 30.9, 34.9 0.14


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 37.58 1.3094 40.1778 34.9822
129S1/SvImJ m 37.51 1.3094 40.1078 34.9122
129SB6F1 f 31.585 1.3094 34.1828 28.9872
129SB6F1 m 31.76 1.3094 34.3578 29.1622
A/J f 38.235 1.3094 40.8328 35.6372
A/J m 33.185 0.756 34.6848 31.6852
C57BL/6J f 31.142 0.4141 31.9635 30.3205
C57BL/6J m 31.0268 0.3044 31.6307 30.4228
CAST/EiJ f 29.806 0.8281 31.449 28.163
CAST/EiJ m 28.465 1.3094 31.0628 25.8672
CASTPWKF1 f 30.2 0.8281 31.843 28.557
CASTPWKF1 m 29.755 0.756 31.2548 28.2552
NODNZOF1 f 32.715 1.3094 35.3128 30.1172
NODNZOF1 m 32.88 1.3094 35.4778 30.2822
NOD/ShiLtJ f 45.4633 1.0691 47.5844 43.3422
NOD/ShiLtJ m 39.41 1.0691 41.5311 37.2889
PWK/PhJ f 37.105 1.3094 39.7028 34.5072
PWK/PhJ m 33.6125 0.9259 35.4494 31.7756
WSBB6F1 f 31.265 1.3094 33.8628 28.6672
WSBB6F1 m 31.2267 1.0691 33.3478 29.1056
WSBNZOF1 f 33.115 0.756 34.6148 31.6152
WSBNZOF1 m 31.4725 0.9259 33.3094 29.6356


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 37.545 0.9259 39.3819 35.7081
129SB6F1 both 31.6725 0.9259 33.5094 29.8356
A/J both 35.71 0.756 37.2098 34.2102
C57BL/6J both 31.0844 0.257 31.5942 30.5746
CAST/EiJ both 29.1355 0.7747 30.6724 27.5986
CASTPWKF1 both 29.9775 0.5607 31.0898 28.8652
NODNZOF1 both 32.7975 0.9259 34.6344 30.9606
NOD/ShiLtJ both 42.4367 0.756 43.9365 40.9368
PWK/PhJ both 35.3588 0.8018 36.9496 33.7679
WSBB6F1 both 31.2458 0.8452 32.9227 29.569
WSBNZOF1 both 32.2938 0.5977 33.4795 31.108




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA