Project measure / variable:   Chesler2   MCH

ID, description, units MPD:43424   MCH   mean RBC corpuscular hemoglobin (MCH)   [pg]  
Data set, strains Chesler2   CC diallel w/par   49 strains     sex: both     age: 7-15wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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Chesler2 - mean RBC corpuscular hemoglobin (MCH)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 18.1 14.5 14.6 14.5 — — 14.4 —
A ♀ — 17.9 14.8 — — 14.6 — —
B6 ♀ 15.4 16.1 14.2 — 15.1 14.3 14.6 —
CAST ♀ — 14.0 13.5 12.9 — 14.5 14.2 14.4
NOD ♀ — 15.2 14.9 — 23.0 15.2 — —
NZO ♀ 14.5 14.2 — — — — — 14.0
PWK ♀ 15.0 14.8 — — 15.4 — 17.8 —
WSB ♀ 14.7 14.8 14.4 — 15.2 14.7 15.7 13.3

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 17.6 13.9 14.2 — 14.8 14.3 — —
A ♀ — 15.7 14.7 — 15.5 — 13.6 14.0
B6 ♀ — 14.7 13.8 — 15.1 14.9 — —
CAST ♀ 14.1 13.4 13.9 12.1 14.4 13.9 13.5 —
NOD ♀ — — — — 19.2 15.3 — —
NZO ♀ — — 14.6 — 17.6 14.6 — —
PWK ♀ — 14.2 — — — — 14.7 —
WSB ♀ — 14.9 14.3 13.9 14.1 15.0 — 13.5

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested38 strains34 strains
Mean of the strain means15.1   pg 14.6   pg
Median of the strain means14.6   pg 14.4   pg
SD of the strain means± 1.71 ± 1.32
Coefficient of variation (CV)0.114 0.0900
Min–max range of strain means12.9   –   23.0   pg 12.1   –   19.2   pg
Mean sample size per strain1.9   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9.1371 9.1371 11.3838 0.0011
strain 10 321.0666 32.1067 40.0012 < 0.0001
sex:strain 10 29.1577 2.9158 3.6327 0.0004
Residuals 99 79.4616 0.8026


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 18.1 0.0849   2   0.06 0.00469 18.0, 18.2 1.76
129S1/SvImJ m 17.6 0.438   2   0.31 0.025 17.2, 17.9 2.24
129SAF1 f 14.5 0.0   1   0.0 0.0 14.5, 14.5 -0.34
129SAF1 m 13.9 0.106   2   0.075 0.00764 13.8, 14.0 -0.57
129SB6F1 f 14.6 0.573   2   0.405 0.0392 14.2, 15.0 -0.29
129SB6F1 m 14.2 0.0566   2   0.04 0.00398 14.2, 14.3 -0.34
129SCASTF1 f 14.5 0.559   2   0.395 0.0385 14.1, 14.9 -0.34
129SNODF1 m 14.8 0.297   2   0.21 0.0201 14.6, 15.0 0.12
129SNZOF1 m 14.3 0.0141   2   0.01 0.000992 14.2, 14.3 -0.26
129SPWKF1 f 14.4 0.0   1   0.0 0.0 14.4, 14.4 -0.4
AB6F1 f 14.8 0.0   1   0.0 0.0 14.8, 14.8 -0.17
AB6F1 m 14.7 0.649   4 0.324 0.0441 14.2, 15.7 0.04
A/J f 17.9 0.212   2   0.15 0.0118 17.8, 18.1 1.64
A/J m 15.7 2.1   6 0.856 0.134 14.0, 18.7 0.8
ANODF1 m 15.5 0.347   7 0.131 0.0223 15.2, 16.0 0.65
ANZOF1 f 14.6 0.0   1   0.0 0.0 14.6, 14.6 -0.29
APWKF1 m 13.6 0.0   1   0.0 0.0 13.6, 13.6 -0.79
AWSBF1 m 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.49
B6129SF1/J f 15.4 1.13   2   0.8 0.0735 14.6, 16.2 0.18
B6AF1/J f 16.1 0.0   1   0.0 0.0 16.1, 16.1 0.59
B6AF1/J m 14.7 0.0   1   0.0 0.0 14.7, 14.7 0.04
B6NODF1 f 15.1 0.0   1   0.0 0.0 15.1, 15.1 0.01
B6NODF1 m 15.1 0.0495   2   0.035 0.00327 15.1, 15.2 0.34
B6NZOF1 f 14.3 0.0   1   0.0 0.0 14.3, 14.3 -0.46
B6NZOF1 m 14.9 0.0   1   0.0 0.0 14.9, 14.9 0.19
B6PWKF1 f 14.6 0.0   1   0.0 0.0 14.6, 14.6 -0.29
C57BL/6J f 14.2 0.204   20 0.0455 0.0144 13.8, 14.6 -0.52
C57BL/6J m 13.8 0.321   37 0.0527 0.0232 13.1, 14.6 -0.64
CAST129SF1 m 14.1 0.0707   2   0.05 0.00502 14.0, 14.1 -0.41
CASTAF1 f 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.64
CASTAF1 m 13.4 0.156   2   0.11 0.0117 13.2, 13.5 -0.95
CASTB6F1 f 13.5 0.0   1   0.0 0.0 13.5, 13.5 -0.93
CASTB6F1 m 13.9 0.0924   3 0.0533 0.00665 13.8, 13.9 -0.57
CAST/EiJ f 12.9 0.636   5 0.284 0.0494 11.8, 13.3 -1.28
CAST/EiJ m 12.1 0.106   2   0.075 0.00873 12.1, 12.2 -1.93
CASTNODF1 m 14.4 0.0   1   0.0 0.0 14.4, 14.4 -0.19
CASTNZOF1 f 14.5 0.97   4 0.485 0.0671 13.7, 15.9 -0.34
CASTNZOF1 m 13.9 0.0   1   0.0 0.0 13.9, 13.9 -0.57
CASTPWKF1 f 14.2 0.269   5 0.12 0.0189 13.8, 14.5 -0.52
CASTPWKF1 m 13.5 0.194   6 0.0792 0.0144 13.1, 13.7 -0.87
CASTWSBF1 f 14.4 1.5   2   1.06 0.104 13.3, 15.4 -0.4
NODAF1 f 15.2 0.0   1   0.0 0.0 15.2, 15.2 0.06
NODB6F1 f 14.9 0.321   3 0.185 0.0216 14.5, 15.2 -0.11
NODNZOF1 f 15.2 0.184   2   0.13 0.0121 15.1, 15.3 0.06
NODNZOF1 m 15.3 0.721   2   0.51 0.0471 14.8, 15.8 0.5
NOD/ShiLtJ f 23.0 3.51   2   2.48 0.152 20.6, 25.5 4.62
NOD/ShiLtJ m 19.2 0.43   3 0.248 0.0224 18.7, 19.5 3.45
NZO129SF1 f 14.5 0.0   1   0.0 0.0 14.5, 14.5 -0.34
NZOAF1 f 14.2 0.0   1   0.0 0.0 14.2, 14.2 -0.52
NZOB6F1 m 14.6 0.0   1   0.0 0.0 14.6, 14.6 -0.04
NZO/HlLtJ m 14.6 0.0   1   0.0 0.0 14.6, 14.6 -0.04
NZONODF1 m 17.6 0.0   1   0.0 0.0 17.6, 17.6 2.24
NZOWSBF1 f 14.0 0.0721   3 0.0416 0.00515 13.9, 14.1 -0.64
PWK129SF1 f 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.05
PWKAF1 f 14.8 0.0   1   0.0 0.0 14.8, 14.8 -0.17
PWKAF1 m 14.2 0.0   1   0.0 0.0 14.2, 14.2 -0.34
PWKNODF1 f 15.4 0.0   1   0.0 0.0 15.4, 15.4 0.18
PWK/PhJ f 17.8 0.686   2   0.485 0.0385 17.3, 18.3 1.58
PWK/PhJ m 14.7 3.1   4 1.55 0.211 11.6, 17.5 0.04
WSB129SF1 f 14.7 0.0   1   0.0 0.0 14.7, 14.7 -0.23
WSBAF1 f 14.8 0.0   1   0.0 0.0 14.8, 14.8 -0.17
WSBAF1 m 14.9 0.771   2   0.545 0.0518 14.3, 15.4 0.19
WSBB6F1 f 14.4 0.424   2   0.3 0.0294 14.2, 14.8 -0.4
WSBB6F1 m 14.3 0.49   3 0.283 0.0343 13.7, 14.7 -0.26
WSBCASTF1 m 13.9 0.753   3 0.435 0.054 13.1, 14.6 -0.57
WSB/EiJ f 13.3 0.785   2   0.555 0.0589 12.8, 13.9 -1.04
WSB/EiJ m 13.5 0.0   1   0.0 0.0 13.5, 13.5 -0.87
WSBNODF1 f 15.2 0.0   1   0.0 0.0 15.2, 15.2 0.06
WSBNODF1 m 14.1 0.82   2   0.58 0.0582 13.5, 14.7 -0.41
WSBNZOF1 f 14.7 0.737   6 0.301 0.0503 14.1, 16.1 -0.23
WSBNZOF1 m 15.0 1.22   4 0.608 0.0813 14.0, 16.7 0.27
WSBPWKF1 f 15.7 1.14   2   0.805 0.0723 14.9, 16.6 0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 18.1 0.6335 19.357 16.843
129S1/SvImJ m 17.56 0.6335 18.817 16.303
129SB6F1 f 14.595 0.6335 15.852 13.338
129SB6F1 m 14.22 0.6335 15.477 12.963
A/J f 17.94 0.6335 19.197 16.683
A/J m 15.6583 0.3658 16.3841 14.9326
C57BL/6J f 14.1675 0.2003 14.565 13.77
C57BL/6J m 13.8354 0.1473 14.1277 13.5432
CAST/EiJ f 12.884 0.4007 13.679 12.089
CAST/EiJ m 12.145 0.6335 13.402 10.888
CASTPWKF1 f 14.242 0.4007 15.037 13.447
CASTPWKF1 m 13.5117 0.3658 14.2374 12.7859
NODNZOF1 f 15.19 0.6335 16.447 13.933
NODNZOF1 m 15.31 0.6335 16.567 14.053
NOD/ShiLtJ f 23.04 0.6335 24.297 21.783
NOD/ShiLtJ m 19.1733 0.5173 20.1997 18.147
PWK/PhJ f 17.815 0.6335 19.072 16.558
PWK/PhJ m 14.6575 0.448 15.5463 13.7687
WSBB6F1 f 14.45 0.6335 15.707 13.193
WSBB6F1 m 14.2833 0.5173 15.3097 13.257
WSBNZOF1 f 14.6633 0.3658 15.3891 13.9376
WSBNZOF1 m 14.9675 0.448 15.8563 14.0787


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 17.83 0.448 18.7188 16.9412
129SB6F1 both 14.4075 0.448 15.2963 13.5187
A/J both 16.7992 0.3658 17.5249 16.0734
C57BL/6J both 14.0015 0.1243 14.2481 13.7548
CAST/EiJ both 12.5145 0.3748 13.2582 11.7708
CASTPWKF1 both 13.8768 0.2712 14.415 13.3386
NODNZOF1 both 15.25 0.448 16.1388 14.3612
NOD/ShiLtJ both 21.1067 0.4089 21.9181 20.2953
PWK/PhJ both 16.2363 0.3879 17.006 15.4665
WSBB6F1 both 14.3667 0.4089 15.1781 13.5553
WSBNZOF1 both 14.8154 0.2892 15.3892 14.2417




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA