Phenotype measure:   Chesler2   MCV

ID, description, units MPD:43422   MCV   mean RBC corpuscular volume (MCV)   [fL]
Data set, strains Chesler2   CC diallel w/par   38 strains     sex: both     age: 7-15wks
Procedure complete blood count
Ontology mappings

  STRAIN COMPARISON PLOT
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Chesler2 - mean RBC corpuscular volume (MCV)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 48.0 47.0 46.0 47.5 47.0
A ♀ 47.0 45.0 45.0
B6 ♀ 46.0 45.0 45.5 46.0 45.0 46.0
CAST ♀ 47.0 43.0 43.2 44.2 47.0 45.0
NOD ♀ 47.0 46.3 49.0 46.5
NZO ♀ 46.0 44.0 44.3
PWK ♀ 49.0 49.0 48.0 48.0
WSB ♀ 47.0 47.0 46.0 48.0 44.5 47.5 45.5

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 47.0 45.5 45.0 46.5 45.5
A ♀ 47.3 45.0 48.4 46.0 46.0
B6 ♀ 45.0 44.6 47.0 45.0
CAST ♀ 45.5 44.5 44.0 42.5 46.0 44.0 45.2
NOD ♀ 48.7 46.5
NZO ♀ 45.0 52.0 44.0
PWK ♀ 48.0 43.5
WSB ♀ 46.5 45.7 45.7 45.5 47.8 46.0

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested38 strains34 strains
Mean of the strain means46.3   fL 45.9   fL
Median of the strain means46.1   fL 45.6   fL
SD of the strain means± 1.54 ± 1.76
Coefficient of variation (CV)0.0333 0.0383
Min–max range of strain means43.0   –   49.0   fL 42.5   –   52.0   fL
Mean sample size per strain1.9   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7.7029 7.7029 3.3281 0.0711
strain 10 173.8914 17.3891 7.5133 < 0.0001
sex:strain 10 63.473 6.3473 2.7425 0.0051
Residuals 99 229.1311 2.3145


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 48.0 0.0   2   0.0 0.0 48.0, 48.0 1.13
129S1/SvImJ m 47.0 0.0   2   0.0 0.0 47.0, 47.0 0.63
129SAF1 f 47.0 0.0   1   0.0 0.0 47.0, 47.0 0.48
129SAF1 m 45.5 0.707   2   0.5 0.0155 45.0, 46.0 -0.22
129SB6F1 f 46.0 0.0   2   0.0 0.0 46.0, 46.0 -0.17
129SB6F1 m 45.0 0.0   2   0.0 0.0 45.0, 45.0 -0.51
129SCASTF1 f 47.5 2.12   2   1.5 0.0447 46.0, 49.0 0.8
129SNODF1 m 46.5 0.707   2   0.5 0.0152 46.0, 47.0 0.34
129SNZOF1 m 45.5 0.707   2   0.5 0.0155 45.0, 46.0 -0.22
129SPWKF1 f 47.0 0.0   1   0.0 0.0 47.0, 47.0 0.48
AB6F1 f 45.0 0.0   1   0.0 0.0 45.0, 45.0 -0.82
AB6F1 m 45.0 1.15   4 0.577 0.0257 44.0, 46.0 -0.51
A/J f 47.0 0.0   2   0.0 0.0 47.0, 47.0 0.48
A/J m 47.3 1.03   6 0.422 0.0218 46.0, 49.0 0.8
ANODF1 m 48.4 0.535   7 0.202 0.011 48.0, 49.0 1.43
ANZOF1 f 45.0 0.0   1   0.0 0.0 45.0, 45.0 -0.82
APWKF1 m 46.0 0.0   1   0.0 0.0 46.0, 46.0 0.06
AWSBF1 m 46.0 0.0   1   0.0 0.0 46.0, 46.0 0.06
B6129SF1/J f 46.0 1.41   2   1.0 0.0307 45.0, 47.0 -0.17
B6AF1/J f 45.0 0.0   1   0.0 0.0 45.0, 45.0 -0.82
B6AF1/J m 45.0 0.0   1   0.0 0.0 45.0, 45.0 -0.51
B6NODF1 f 46.0 0.0   1   0.0 0.0 46.0, 46.0 -0.17
B6NODF1 m 47.0 0.0   2   0.0 0.0 47.0, 47.0 0.63
B6NZOF1 f 45.0 0.0   1   0.0 0.0 45.0, 45.0 -0.82
B6NZOF1 m 45.0 0.0   1   0.0 0.0 45.0, 45.0 -0.51
B6PWKF1 f 46.0 0.0   1   0.0 0.0 46.0, 46.0 -0.17
C57BL/6J f 45.5 0.946   20 0.212 0.0208 44.0, 48.0 -0.5
C57BL/6J m 44.6 0.867   37 0.143 0.0195 42.0, 46.0 -0.74
CAST129SF1 m 45.5 2.12   2   1.5 0.0466 44.0, 47.0 -0.22
CASTAF1 f 47.0 0.0   1   0.0 0.0 47.0, 47.0 0.48
CASTAF1 m 44.5 0.707   2   0.5 0.0159 44.0, 45.0 -0.79
CASTB6F1 f 43.0 0.0   1   0.0 0.0 43.0, 43.0 -2.12
CASTB6F1 m 44.0 0.0   3 0.0 0.0 44.0, 44.0 -1.08
CAST/EiJ f 43.2 1.92   5 0.86 0.0445 40.0, 45.0 -1.99
CAST/EiJ m 42.5 0.707   2   0.5 0.0166 42.0, 43.0 -1.93
CASTNODF1 m 46.0 0.0   1   0.0 0.0 46.0, 46.0 0.06
CASTNZOF1 f 44.2 0.5   4 0.25 0.0113 44.0, 45.0 -1.34
CASTNZOF1 m 44.0 0.0   1   0.0 0.0 44.0, 44.0 -1.08
CASTPWKF1 f 47.0 0.707   5 0.316 0.015 46.0, 48.0 0.48
CASTPWKF1 m 45.2 0.408   6 0.167 0.00904 45.0, 46.0 -0.4
CASTWSBF1 f 45.0 0.0   2   0.0 0.0 45.0, 45.0 -0.82
NODAF1 f 47.0 0.0   1   0.0 0.0 47.0, 47.0 0.48
NODB6F1 f 46.3 0.577   3 0.333 0.0125 46.0, 47.0 0.02
NODNZOF1 f 46.5 0.707   2   0.5 0.0152 46.0, 47.0 0.15
NODNZOF1 m 46.5 0.707   2   0.5 0.0152 46.0, 47.0 0.34
NOD/ShiLtJ f 49.0 1.41   2   1.0 0.0289 48.0, 50.0 1.78
NOD/ShiLtJ m 48.7 0.577   3 0.333 0.0119 48.0, 49.0 1.6
NZO129SF1 f 46.0 0.0   1   0.0 0.0 46.0, 46.0 -0.17
NZOAF1 f 44.0 0.0   1   0.0 0.0 44.0, 44.0 -1.47
NZOB6F1 m 45.0 0.0   1   0.0 0.0 45.0, 45.0 -0.51
NZO/HlLtJ m 44.0 0.0   1   0.0 0.0 44.0, 44.0 -1.08
NZONODF1 m 52.0 0.0   1   0.0 0.0 52.0, 52.0 3.48
NZOWSBF1 f 44.3 0.577   3 0.333 0.013 44.0, 45.0 -1.27
PWK129SF1 f 49.0 0.0   1   0.0 0.0 49.0, 49.0 1.78
PWKAF1 f 49.0 0.0   1   0.0 0.0 49.0, 49.0 1.78
PWKAF1 m 48.0 0.0   1   0.0 0.0 48.0, 48.0 1.2
PWKNODF1 f 48.0 0.0   1   0.0 0.0 48.0, 48.0 1.13
PWK/PhJ f 48.0 0.0   2   0.0 0.0 48.0, 48.0 1.13
PWK/PhJ m 43.5 4.36   4 2.18 0.1 37.0, 46.0 -1.36
WSB129SF1 f 47.0 0.0   1   0.0 0.0 47.0, 47.0 0.48
WSBAF1 f 47.0 0.0   1   0.0 0.0 47.0, 47.0 0.48
WSBAF1 m 46.5 0.707   2   0.5 0.0152 46.0, 47.0 0.34
WSBB6F1 f 46.0 0.0   2   0.0 0.0 46.0, 46.0 -0.17
WSBB6F1 m 45.7 1.15   3 0.667 0.0253 45.0, 47.0 -0.11
WSBCASTF1 m 45.7 1.15   3 0.667 0.0253 45.0, 47.0 -0.11
WSB/EiJ f 45.5 0.707   2   0.5 0.0155 45.0, 46.0 -0.5
WSB/EiJ m 46.0 0.0   1   0.0 0.0 46.0, 46.0 0.06
WSBNODF1 f 48.0 0.0   1   0.0 0.0 48.0, 48.0 1.13
WSBNODF1 m 45.5 2.12   2   1.5 0.0466 44.0, 47.0 -0.22
WSBNZOF1 f 44.5 0.548   6 0.224 0.0123 44.0, 45.0 -1.14
WSBNZOF1 m 47.8 5.68   4 2.84 0.119 44.0, 56.0 1.08
WSBPWKF1 f 47.5 0.707   2   0.5 0.0149 47.0, 48.0 0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 48.0 1.0757 50.1345 45.8655
129S1/SvImJ m 47.0 1.0757 49.1345 44.8655
129SB6F1 f 46.0 1.0757 48.1345 43.8655
129SB6F1 m 45.0 1.0757 47.1345 42.8655
A/J f 47.0 1.0757 49.1345 44.8655
A/J m 47.3333 0.6211 48.5657 46.101
C57BL/6J f 45.5 0.3402 46.175 44.825
C57BL/6J m 44.5676 0.2501 45.0638 44.0713
CAST/EiJ f 43.2 0.6804 44.55 41.85
CAST/EiJ m 42.5 1.0757 44.6345 40.3655
CASTPWKF1 f 47.0 0.6804 48.35 45.65
CASTPWKF1 m 45.1667 0.6211 46.399 43.9343
NODNZOF1 f 46.5 1.0757 48.6345 44.3655
NODNZOF1 m 46.5 1.0757 48.6345 44.3655
NOD/ShiLtJ f 49.0 1.0757 51.1345 46.8655
NOD/ShiLtJ m 48.6667 0.8783 50.4095 46.9238
PWK/PhJ f 48.0 1.0757 50.1345 45.8655
PWK/PhJ m 43.5 0.7607 45.0093 41.9907
WSBB6F1 f 46.0 1.0757 48.1345 43.8655
WSBB6F1 m 45.6667 0.8783 47.4095 43.9238
WSBNZOF1 f 44.5 0.6211 45.7324 43.2676
WSBNZOF1 m 47.75 0.7607 49.2593 46.2407


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 47.5 0.7607 49.0093 45.9907
129SB6F1 both 45.5 0.7607 47.0093 43.9907
A/J both 47.1667 0.6211 48.399 45.9343
C57BL/6J both 45.0338 0.2111 45.4527 44.6149
CAST/EiJ both 42.85 0.6364 44.1128 41.5872
CASTPWKF1 both 46.0833 0.4606 46.9973 45.1694
NODNZOF1 both 46.5 0.7607 48.0093 44.9907
NOD/ShiLtJ both 48.8333 0.6944 50.2112 47.4555
PWK/PhJ both 45.75 0.6588 47.0571 44.4429
WSBB6F1 both 45.8333 0.6944 47.2112 44.4555
WSBNZOF1 both 46.125 0.491 47.0993 45.1507




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA