Phenotype measure:   Chesler2   pct_GRA

ID, description, units MPD:43419   pct_GRA   granulocyte differential (GRA; percentage of total viable WBC)   [%]
Data set, strains Chesler2   CC diallel w/par   38 strains     sex: both     age: 7-15wks
Procedure complete blood count
Ontology mappings

  STRAIN COMPARISON PLOT
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Chesler2 - granulocyte differential (GRA; percentage of total viable WBC)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 29.5 50.4 40.0 51.4 31.7
A ♀ 47.5 41.3 38.0
B6 ♀ 45.6 47.6 28.1 35.9 46.0 34.1
CAST ♀ 45.2 44.8 36.7 38.8 32.8 45.3
NOD ♀ 42.2 45.0 47.9 50.5
NZO ♀ 49.2 47.9 46.6
PWK ♀ 31.5 43.3 53.4 38.7
WSB ♀ 32.7 34.8 43.2 30.3 39.1 27.5 33.5

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ 38.5 40.5 33.2 51.5 47.4
A ♀ 45.1 40.2 46.2 32.2 51.1
B6 ♀ 37.4 29.9 50.9 43.3
CAST ♀ 45.1 46.8 36.9 36.2 48.1 36.2 33.5
NOD ♀ 49.2 45.9
NZO ♀ 40.5 45.4
PWK ♀ 28.0 42.4
WSB ♀ 49.2 44.0 44.2 43.6 40.3 44.6

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested38 strains33 strains
Mean of the strain means40.7   % 42.0   %
Median of the strain means41.8   % 43.6   %
SD of the strain means± 7.28 ± 6.26
Coefficient of variation (CV)0.179 0.149
Min–max range of strain means27.5   –   53.4   % 28.0   –   51.5   %
Mean sample size per strain1.9   mice 2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2877 0.2877 0.006 0.9386
strain 10 5506.9644 550.6964 11.4187 < 0.0001
sex:strain 10 193.0999 19.31 0.4004 0.9436
Residuals 100 4822.7419 48.2274


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 29.5 0.495   2   0.35 0.0168 29.1, 29.8 -1.54
129S1/SvImJ m 38.5 9.48   2   6.7 0.246 31.8, 45.2 -0.57
129SAF1 f 50.4 0.0   1   0.0 0.0 50.4, 50.4 1.33
129SAF1 m 40.5 7.78   2   5.5 0.192 35.0, 46.0 -0.25
129SB6F1 f 40.0 3.46   2   2.45 0.0867 37.5, 42.4 -0.1
129SB6F1 m 33.2 0.354   2   0.25 0.0106 33.0, 33.5 -1.41
129SCASTF1 f 51.4 8.77   2   6.2 0.171 45.2, 57.6 1.46
129SNODF1 m 51.5 2.05   2   1.45 0.0398 50.1, 53.0 1.51
129SNZOF1 m 47.4 1.27   2   0.9 0.0269 46.5, 48.3 0.86
129SPWKF1 f 31.7 0.0   1   0.0 0.0 31.7, 31.7 -1.24
AB6F1 f 41.3 0.0   1   0.0 0.0 41.3, 41.3 0.08
AB6F1 m 40.2 3.12   4 1.56 0.0776 36.6, 43.9 -0.29
A/J f 47.5 4.03   2   2.85 0.0849 44.6, 50.3 0.93
A/J m 45.1 6.12   6 2.5 0.136 34.7, 52.2 0.49
ANODF1 m 46.2 3.83   7 1.45 0.0828 40.2, 50.8 0.66
ANZOF1 f 38.0 0.0   1   0.0 0.0 38.0, 38.0 -0.38
APWKF1 m 32.2 0.0   1   0.0 0.0 32.2, 32.2 -1.57
AWSBF1 m 51.1 0.0   1   0.0 0.0 51.1, 51.1 1.45
B6129SF1/J f 45.6 4.1   2   2.9 0.0899 42.7, 48.5 0.67
B6AF1/J f 47.6 0.0   1   0.0 0.0 47.6, 47.6 0.94
B6AF1/J m 37.4 0.0   1   0.0 0.0 37.4, 37.4 -0.74
B6NODF1 f 35.9 0.0   1   0.0 0.0 35.9, 35.9 -0.66
B6NODF1 m 50.9 1.2   2   0.85 0.0236 50.0, 51.7 1.41
B6NZOF1 f 46.0 0.0   1   0.0 0.0 46.0, 46.0 0.72
B6NZOF1 m 43.3 0.0   1   0.0 0.0 43.3, 43.3 0.2
B6PWKF1 f 34.1 0.0   1   0.0 0.0 34.1, 34.1 -0.91
C57BL/6J f 28.1 6.74   20 1.51 0.24 18.3, 40.9 -1.74
C57BL/6J m 29.9 6.86   37 1.13 0.23 20.6, 44.5 -1.94
CAST129SF1 m 45.1 2.4   2   1.7 0.0533 43.4, 46.8 0.49
CASTAF1 f 45.2 0.0   1   0.0 0.0 45.2, 45.2 0.61
CASTAF1 m 46.8 5.09   2   3.6 0.109 43.2, 50.4 0.76
CASTB6F1 f 44.8 0.0   1   0.0 0.0 44.8, 44.8 0.56
CASTB6F1 m 36.9 8.46   3 4.88 0.229 29.1, 45.9 -0.82
CAST/EiJ f 36.7 5.71   5 2.55 0.156 27.9, 42.4 -0.55
CAST/EiJ m 36.2 4.31   2   3.05 0.119 33.2, 39.3 -0.93
CASTNODF1 m 48.1 0.0   1   0.0 0.0 48.1, 48.1 0.97
CASTNZOF1 f 38.8 7.09   4 3.55 0.183 28.8, 45.5 -0.27
CASTNZOF1 m 36.2 0.0   1   0.0 0.0 36.2, 36.2 -0.93
CASTPWKF1 f 32.8 4.49   5 2.01 0.137 28.8, 40.1 -1.09
CASTPWKF1 m 33.5 7.7   6 3.15 0.23 23.2, 42.3 -1.36
CASTWSBF1 f 45.3 8.06   2   5.7 0.178 39.6, 51.0 0.63
NODAF1 f 42.2 0.0   1   0.0 0.0 42.2, 42.2 0.2
NODB6F1 f 45.0 5.26   3 3.04 0.117 40.0, 50.5 0.59
NODNZOF1 f 50.5 3.61   2   2.55 0.0715 47.9, 53.0 1.34
NODNZOF1 m 45.9 12.9   2   9.1 0.28 36.8, 55.0 0.62
NOD/ShiLtJ f 47.9 4.46   3 2.58 0.0931 42.9, 51.4 0.98
NOD/ShiLtJ m 49.2 4.24   3 2.45 0.0863 44.3, 52.1 1.14
NZO129SF1 f 49.2 0.0   1   0.0 0.0 49.2, 49.2 1.16
NZOAF1 f 47.9 0.0   1   0.0 0.0 47.9, 47.9 0.98
NZOB6F1 m 40.5 0.0   1   0.0 0.0 40.5, 40.5 -0.25
NZO/HlLtJ m 45.4 0.0   1   0.0 0.0 45.4, 45.4 0.54
NZOWSBF1 f 46.6 18.3   3 10.6 0.394 31.5, 67.0 0.81
PWK129SF1 f 31.5 0.0   1   0.0 0.0 31.5, 31.5 -1.27
PWKAF1 f 43.3 0.0   1   0.0 0.0 43.3, 43.3 0.35
PWKAF1 m 28.0 0.0   1   0.0 0.0 28.0, 28.0 -2.24
PWKNODF1 f 53.4 0.0   1   0.0 0.0 53.4, 53.4 1.74
PWK/PhJ f 38.7 0.707   2   0.5 0.0183 38.2, 39.2 -0.28
PWK/PhJ m 42.4 12.0   4 6.0 0.283 33.1, 59.8 0.06
WSB129SF1 f 32.7 0.0   1   0.0 0.0 32.7, 32.7 -1.1
WSBAF1 f 34.8 0.0   1   0.0 0.0 34.8, 34.8 -0.82
WSBAF1 m 49.2 5.87   2   4.15 0.119 45.1, 53.4 1.14
WSBB6F1 f 43.2 6.36   2   4.5 0.147 38.7, 47.7 0.34
WSBB6F1 m 44.0 5.16   3 2.98 0.117 39.7, 49.7 0.31
WSBCASTF1 m 44.2 4.82   3 2.78 0.109 38.6, 47.1 0.34
WSB/EiJ f 33.5 2.76   2   1.95 0.0824 31.5, 35.4 -0.99
WSB/EiJ m 44.6 0.0   1   0.0 0.0 44.6, 44.6 0.41
WSBNODF1 f 30.3 0.0   1   0.0 0.0 30.3, 30.3 -1.43
WSBNODF1 m 43.6 3.25   2   2.3 0.0746 41.3, 45.9 0.25
WSBNZOF1 f 39.1 8.28   6 3.38 0.212 30.4, 51.9 -0.22
WSBNZOF1 m 40.3 10.2   4 5.1 0.253 30.9, 54.8 -0.28
WSBPWKF1 f 27.5 2.12   2   1.5 0.0771 26.0, 29.0 -1.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 29.45 4.9106 39.1924 19.7076
129S1/SvImJ m 38.5 4.9106 48.2424 28.7576
129SB6F1 f 39.95 4.9106 49.6924 30.2076
129SB6F1 m 33.25 4.9106 42.9924 23.5076
A/J f 47.45 4.9106 57.1924 37.7076
A/J m 45.05 2.8351 50.6748 39.4252
C57BL/6J f 28.085 1.5529 31.1658 25.0042
C57BL/6J m 29.8595 1.1417 32.1245 27.5944
CAST/EiJ f 36.7 3.1057 42.8617 30.5383
CAST/EiJ m 36.25 4.9106 45.9924 26.5076
CASTPWKF1 f 32.82 3.1057 38.9817 26.6583
CASTPWKF1 m 33.4667 2.8351 39.0915 27.8419
NODNZOF1 f 50.45 4.9106 60.1924 40.7076
NODNZOF1 m 45.9 4.9106 55.6424 36.1576
NOD/ShiLtJ f 47.9333 4.0095 55.888 39.9787
NOD/ShiLtJ m 49.1667 4.0095 57.1213 41.212
PWK/PhJ f 38.7 4.9106 48.4424 28.9576
PWK/PhJ m 42.375 3.4723 49.2639 35.4861
WSBB6F1 f 43.2 4.9106 52.9424 33.4576
WSBB6F1 m 43.9667 4.0095 51.9213 36.012
WSBNZOF1 f 39.1333 2.8351 44.7581 33.5085
WSBNZOF1 m 40.3 3.4723 47.1889 33.4111


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 33.975 3.4723 40.8639 27.0861
129SB6F1 both 36.6 3.4723 43.4889 29.7111
A/J both 46.25 2.8351 51.8748 40.6252
C57BL/6J both 28.9722 0.9637 30.8842 27.0603
CAST/EiJ both 36.475 2.9051 42.2387 30.7113
CASTPWKF1 both 33.1433 2.1026 37.3148 28.9719
NODNZOF1 both 48.175 3.4723 55.0639 41.2861
NOD/ShiLtJ both 48.55 2.8351 54.1748 42.9252
PWK/PhJ both 40.5375 3.0071 46.5035 34.5715
WSBB6F1 both 43.5833 3.1698 49.872 37.2946
WSBNZOF1 both 39.7167 2.2414 44.1635 35.2699




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA